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Multimodal handheld adaptive optics scanning laser ophthalmoscope.

Publication ,  Journal Article
Hagan, K; DuBose, T; Cunefare, D; Waterman, G; Park, J; Simmerer, C; Kuo, AN; McNabb, RP; Izatt, JA; Farsiu, S
Published in: Opt Lett
September 1, 2020

Non-confocal adaptive optics scanning laser ophthalmoscopy (AOSLO) has enhanced the study of human retinal photoreceptors by providing complementary information to standard confocal AOSLO images. Previously we developed the first confocal handheld AOSLO (HAOSLO) capable of in vivo cone photoreceptor imaging in supine and non-cooperative patients. Here, we introduce the first multimodal (M-)HAOSLO for confocal and non-confocal split-detection (SD) imaging to allow for more comprehensive patient data collection. Aside from its unprecedented miniature size and weight, M-HAOSLO is also the first system to perform sensorless wavefront-corrected SD imaging of cone photoreceptors.

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Published In

Opt Lett

DOI

EISSN

1539-4794

Publication Date

September 1, 2020

Volume

45

Issue

17

Start / End Page

4940 / 4943

Location

United States

Related Subject Headings

  • Optics
  • Ophthalmoscopes
  • Lasers
  • Image Processing, Computer-Assisted
  • Humans
  • Equipment Design
  • Adult
  • 5102 Atomic, molecular and optical physics
  • 4009 Electronics, sensors and digital hardware
  • 4006 Communications engineering
 

Citation

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Hagan, K., DuBose, T., Cunefare, D., Waterman, G., Park, J., Simmerer, C., … Farsiu, S. (2020). Multimodal handheld adaptive optics scanning laser ophthalmoscope. Opt Lett, 45(17), 4940–4943. https://doi.org/10.1364/OL.402392
Hagan, Kristen, Theodore DuBose, David Cunefare, Gar Waterman, Jongwan Park, Corey Simmerer, Anthony N. Kuo, Ryan P. McNabb, Joseph A. Izatt, and Sina Farsiu. “Multimodal handheld adaptive optics scanning laser ophthalmoscope.Opt Lett 45, no. 17 (September 1, 2020): 4940–43. https://doi.org/10.1364/OL.402392.
Hagan K, DuBose T, Cunefare D, Waterman G, Park J, Simmerer C, et al. Multimodal handheld adaptive optics scanning laser ophthalmoscope. Opt Lett. 2020 Sep 1;45(17):4940–3.
Hagan, Kristen, et al. “Multimodal handheld adaptive optics scanning laser ophthalmoscope.Opt Lett, vol. 45, no. 17, Sept. 2020, pp. 4940–43. Pubmed, doi:10.1364/OL.402392.
Hagan K, DuBose T, Cunefare D, Waterman G, Park J, Simmerer C, Kuo AN, McNabb RP, Izatt JA, Farsiu S. Multimodal handheld adaptive optics scanning laser ophthalmoscope. Opt Lett. 2020 Sep 1;45(17):4940–4943.
Journal cover image

Published In

Opt Lett

DOI

EISSN

1539-4794

Publication Date

September 1, 2020

Volume

45

Issue

17

Start / End Page

4940 / 4943

Location

United States

Related Subject Headings

  • Optics
  • Ophthalmoscopes
  • Lasers
  • Image Processing, Computer-Assisted
  • Humans
  • Equipment Design
  • Adult
  • 5102 Atomic, molecular and optical physics
  • 4009 Electronics, sensors and digital hardware
  • 4006 Communications engineering