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Deep image prior for undersampling high-speed photoacoustic microscopy.

Publication ,  Journal Article
Vu, T; DiSpirito, A; Li, D; Wang, Z; Zhu, X; Chen, M; Jiang, L; Zhang, D; Luo, J; Zhang, YS; Zhou, Q; Horstmeyer, R; Yao, J
Published in: Photoacoustics
June 2021

Photoacoustic microscopy (PAM) is an emerging imaging method combining light and sound. However, limited by the laser's repetition rate, state-of-the-art high-speed PAM technology often sacrifices spatial sampling density (i.e., undersampling) for increased imaging speed over a large field-of-view. Deep learning (DL) methods have recently been used to improve sparsely sampled PAM images; however, these methods often require time-consuming pre-training and large training dataset with ground truth. Here, we propose the use of deep image prior (DIP) to improve the image quality of undersampled PAM images. Unlike other DL approaches, DIP requires neither pre-training nor fully-sampled ground truth, enabling its flexible and fast implementation on various imaging targets. Our results have demonstrated substantial improvement in PAM images with as few as 1.4 % of the fully sampled pixels on high-speed PAM. Our approach outperforms interpolation, is competitive with pre-trained supervised DL method, and is readily translated to other high-speed, undersampling imaging modalities.

Duke Scholars

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Published In

Photoacoustics

DOI

EISSN

2213-5979

ISSN

2213-5979

Publication Date

June 2021

Volume

22

Start / End Page

100266
 

Citation

APA
Chicago
ICMJE
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Vu, T., DiSpirito, A., Li, D., Wang, Z., Zhu, X., Chen, M., … Yao, J. (2021). Deep image prior for undersampling high-speed photoacoustic microscopy. Photoacoustics, 22, 100266. https://doi.org/10.1016/j.pacs.2021.100266
Vu, Tri, Anthony DiSpirito, Daiwei Li, Zixuan Wang, Xiaoyi Zhu, Maomao Chen, Laiming Jiang, et al. “Deep image prior for undersampling high-speed photoacoustic microscopy.Photoacoustics 22 (June 2021): 100266. https://doi.org/10.1016/j.pacs.2021.100266.
Vu T, DiSpirito A, Li D, Wang Z, Zhu X, Chen M, et al. Deep image prior for undersampling high-speed photoacoustic microscopy. Photoacoustics. 2021 Jun;22:100266.
Vu, Tri, et al. “Deep image prior for undersampling high-speed photoacoustic microscopy.Photoacoustics, vol. 22, June 2021, p. 100266. Epmc, doi:10.1016/j.pacs.2021.100266.
Vu T, DiSpirito A, Li D, Wang Z, Zhu X, Chen M, Jiang L, Zhang D, Luo J, Zhang YS, Zhou Q, Horstmeyer R, Yao J. Deep image prior for undersampling high-speed photoacoustic microscopy. Photoacoustics. 2021 Jun;22:100266.
Journal cover image

Published In

Photoacoustics

DOI

EISSN

2213-5979

ISSN

2213-5979

Publication Date

June 2021

Volume

22

Start / End Page

100266