SGC-CAMKK2-1: A Chemical Probe for CAMKK2.
Publication
, Journal Article
Wells, C; Liang, Y; Pulliam, TL; Lin, C; Awad, D; Eduful, B; O'Byrne, S; Hossain, MA; Catta-Preta, CMC; Ramos, PZ; Gileadi, O; Gileadi, C ...
Published in: Cells
January 11, 2023
The serine/threonine protein kinase calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2) plays critical roles in a range of biological processes. Despite its importance, only a handful of inhibitors of CAMKK2 have been disclosed. Having a selective small molecule tool to interrogate this kinase will help demonstrate that CAMKK2 inhibition can be therapeutically beneficial. Herein, we disclose SGC-CAMKK2-1, a selective chemical probe that targets CAMKK2.
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Published In
Cells
DOI
EISSN
2073-4409
Publication Date
January 11, 2023
Volume
12
Issue
2
Location
Switzerland
Related Subject Headings
- 32 Biomedical and clinical sciences
- 31 Biological sciences
Citation
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Wells, C., Liang, Y., Pulliam, T. L., Lin, C., Awad, D., Eduful, B., … Drewry, D. H. (2023). SGC-CAMKK2-1: A Chemical Probe for CAMKK2. Cells, 12(2). https://doi.org/10.3390/cells12020287
Wells, Carrow, Yi Liang, Thomas L. Pulliam, Chenchu Lin, Dominik Awad, Benjamin Eduful, Sean O’Byrne, et al. “SGC-CAMKK2-1: A Chemical Probe for CAMKK2.” Cells 12, no. 2 (January 11, 2023). https://doi.org/10.3390/cells12020287.
Wells C, Liang Y, Pulliam TL, Lin C, Awad D, Eduful B, et al. SGC-CAMKK2-1: A Chemical Probe for CAMKK2. Cells. 2023 Jan 11;12(2).
Wells, Carrow, et al. “SGC-CAMKK2-1: A Chemical Probe for CAMKK2.” Cells, vol. 12, no. 2, Jan. 2023. Pubmed, doi:10.3390/cells12020287.
Wells C, Liang Y, Pulliam TL, Lin C, Awad D, Eduful B, O’Byrne S, Hossain MA, Catta-Preta CMC, Ramos PZ, Gileadi O, Gileadi C, Couñago RM, Stork B, Langendorf CG, Nay K, Oakhill JS, Mukherjee D, Racioppi L, Means AR, York B, McDonnell DP, Scott JW, Frigo DE, Drewry DH. SGC-CAMKK2-1: A Chemical Probe for CAMKK2. Cells. 2023 Jan 11;12(2).
Published In
Cells
DOI
EISSN
2073-4409
Publication Date
January 11, 2023
Volume
12
Issue
2
Location
Switzerland
Related Subject Headings
- 32 Biomedical and clinical sciences
- 31 Biological sciences