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Luigi Racioppi

Associate Professor in Medicine
Medicine, Hematologic Malignancies and Cellular Therapy
103866 - 2006 GSRB1, Durham, NC 27710
905 S. LaSalle St, 2006 GSRB1, Durham, NC 27710

Current Appointments & Affiliations


Associate Professor in Medicine · 2021 - Present Medicine, Hematologic Malignancies and Cellular Therapy, Medicine
Member of the Duke Cancer Institute · 2022 - Present Duke Cancer Institute, Institutes and Centers

Recent Publications


CaMKK2 Regulates Macrophage Polarization Induced by Matrix Stiffness: Implications for Shaping the Immune Response in Stiffened Tissues.

Journal Article Adv Sci (Weinh) · April 2025 Macrophages are essential for immune responses and maintaining tissue homeostasis, exhibiting a wide range of phenotypes depending on their microenvironment. The extracellular matrix (ECM) is a vital component that provides structural support and organizat ... Full text Link to item Cite

Engineering biomaterials to tailor the microenvironment for macrophage–endothelium interactions

Journal Article Nature Reviews Materials · October 1, 2023 Macrophages and endothelial cells (ECs) have essential roles in physiological and pathological conditions by regulating inflammation, vascularization and tissue remodelling. Although the interactions between macrophages and ECs in tissue homeostasis and di ... Full text Cite
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Recent Grants


Creating non-human tended microphysiological systems (CHIPS)

ResearchInvestigator · Awarded by Baylor College of Medicine · 2024 - 2027

Immune-endothelial cell dysfunction in radiation-induced atherosclerosis

ResearchCollaborating Investigator · Awarded by American Heart Association · 2024 - 2025

Artery-on-a-chip for preclinical evaluation of countermeasures against endothelial damage

ResearchCo Investigator · Awarded by The Trustees of Columbia University · 2024 - 2025

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Education, Training & Certifications


University of Naples Federico II (Italy) · 1992 Ph.D.
University of Naples Federico II (Italy) · 1985 M.D.