Current Appointments & Affiliations
Associate Professor in Medicine
·
2021 - Present
Medicine, Hematologic Malignancies and Cellular Therapy,
Medicine
Member of the Duke Cancer Institute
·
2022 - Present
Duke Cancer Institute,
Institutes and Centers
Recent Publications
CaMKK2 Regulates Macrophage Polarization Induced by Matrix Stiffness: Implications for Shaping the Immune Response in Stiffened Tissues.
Journal Article Adv Sci (Weinh) · April 2025 Macrophages are essential for immune responses and maintaining tissue homeostasis, exhibiting a wide range of phenotypes depending on their microenvironment. The extracellular matrix (ECM) is a vital component that provides structural support and organizat ... Full text Link to item CiteEngineering biomaterials to tailor the microenvironment for macrophage–endothelium interactions
Journal Article Nature Reviews Materials · October 1, 2023 Macrophages and endothelial cells (ECs) have essential roles in physiological and pathological conditions by regulating inflammation, vascularization and tissue remodelling. Although the interactions between macrophages and ECs in tissue homeostasis and di ... Full text CiteSupplementary Data from Increased CaMKK2 Expression Is an Adaptive Response That Maintains the Fitness of Tumor-Infiltrating Natural Killer Cells
Other · April 4, 2023 <p>Supplementary Figures and Tables: 5 figures, 3 tables</p> ... Full text CiteRecent Grants
Creating non-human tended microphysiological systems (CHIPS)
ResearchInvestigator · Awarded by Baylor College of Medicine · 2024 - 2027Artery-on-a-chip for preclinical evaluation of countermeasures against endothelial damage
ResearchCo Investigator · Awarded by The Trustees of Columbia University · 2024 - 2025CaMKK2 inhibition as an approach to increase tumor immunity in breast cancers
ResearchPrincipal Investigator · Awarded by Department of Defense · 2020 - 2024View All Grants
Education, Training & Certifications
University of Naples Federico II (Italy) ·
1992
Ph.D.
University of Naples Federico II (Italy) ·
1985
M.D.