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Multi-probe Metabolic Fluorescence Microscopy Captures Poor Tumor Immunogenicity

Publication ,  Conference
Mekha, S; Sunassee, E; Salgado, M; Madonna, M; Crouch, B; Nair, S; Ramanujam, N
Published in: Optical Molecular Probes Imaging and Drug Delivery Omp 2025 in Proceedings Optica Biophotonics Congress 2025 Part of Optica Biophotonics Congress Optics in the Life Sciences
January 1, 2025

Visualizing complex tumor-immune metabolic interactions is imperative to understanding cancer progression. Cocultures of 4T1 tumor cells and CD8+ T cells were imaged for glucose uptake and mitochondrial metabolism. Results point to poor immunogenic tumor phenotype.

Duke Scholars

Published In

Optical Molecular Probes Imaging and Drug Delivery Omp 2025 in Proceedings Optica Biophotonics Congress 2025 Part of Optica Biophotonics Congress Optics in the Life Sciences

DOI

Publication Date

January 1, 2025
 

Citation

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Mekha, S., Sunassee, E., Salgado, M., Madonna, M., Crouch, B., Nair, S., & Ramanujam, N. (2025). Multi-probe Metabolic Fluorescence Microscopy Captures Poor Tumor Immunogenicity. In Optical Molecular Probes Imaging and Drug Delivery Omp 2025 in Proceedings Optica Biophotonics Congress 2025 Part of Optica Biophotonics Congress Optics in the Life Sciences. https://doi.org/10.1364/OMP.2025.OM1E.3
Mekha, S., E. Sunassee, M. Salgado, M. Madonna, B. Crouch, S. Nair, and N. Ramanujam. “Multi-probe Metabolic Fluorescence Microscopy Captures Poor Tumor Immunogenicity.” In Optical Molecular Probes Imaging and Drug Delivery Omp 2025 in Proceedings Optica Biophotonics Congress 2025 Part of Optica Biophotonics Congress Optics in the Life Sciences, 2025. https://doi.org/10.1364/OMP.2025.OM1E.3.
Mekha S, Sunassee E, Salgado M, Madonna M, Crouch B, Nair S, et al. Multi-probe Metabolic Fluorescence Microscopy Captures Poor Tumor Immunogenicity. In: Optical Molecular Probes Imaging and Drug Delivery Omp 2025 in Proceedings Optica Biophotonics Congress 2025 Part of Optica Biophotonics Congress Optics in the Life Sciences. 2025.
Mekha, S., et al. “Multi-probe Metabolic Fluorescence Microscopy Captures Poor Tumor Immunogenicity.” Optical Molecular Probes Imaging and Drug Delivery Omp 2025 in Proceedings Optica Biophotonics Congress 2025 Part of Optica Biophotonics Congress Optics in the Life Sciences, 2025. Scopus, doi:10.1364/OMP.2025.OM1E.3.
Mekha S, Sunassee E, Salgado M, Madonna M, Crouch B, Nair S, Ramanujam N. Multi-probe Metabolic Fluorescence Microscopy Captures Poor Tumor Immunogenicity. Optical Molecular Probes Imaging and Drug Delivery Omp 2025 in Proceedings Optica Biophotonics Congress 2025 Part of Optica Biophotonics Congress Optics in the Life Sciences. 2025.

Published In

Optical Molecular Probes Imaging and Drug Delivery Omp 2025 in Proceedings Optica Biophotonics Congress 2025 Part of Optica Biophotonics Congress Optics in the Life Sciences

DOI

Publication Date

January 1, 2025