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Cognitive effects of nicotine.

Publication ,  Journal Article
Rezvani, AH; Levin, ED
Published in: Biol Psychiatry
February 1, 2001

Nicotine and other nicotinic agonists have been found to improve performance on attention and memory tasks. Clinical studies using nicotine skin patches have demonstrated the efficacy of nicotine in treating cognitive impairments associated with Alzheimer's disease, schizophrenia, and attention-deficit/hyperactivity disorder. Experimental animal studies have demonstrated the persistence of nicotine-induced working memory improvement with chronic exposure, in addition to the efficacy of a variety of nicotinic agonists. Mechanistic studies have found that alpha7 and alpha4beta2 nicotinic receptors in the hippocampus are critical for nicotinic involvement in cognitive function. Clinical and experimental animal studies provide mutually supporting information for the development of novel nicotinic therapies for cognitive dysfunction.

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Published In

Biol Psychiatry

DOI

ISSN

0006-3223

Publication Date

February 1, 2001

Volume

49

Issue

3

Start / End Page

258 / 267

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Receptors, Nicotinic
  • Psychiatry
  • Nicotine
  • Neuropsychological Tests
  • Humans
  • Hippocampus
  • Cognition Disorders
  • Animals
  • Alzheimer Disease
 

Citation

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Rezvani, A. H., & Levin, E. D. (2001). Cognitive effects of nicotine. Biol Psychiatry, 49(3), 258–267. https://doi.org/10.1016/s0006-3223(00)01094-5
Rezvani, A. H., and E. D. Levin. “Cognitive effects of nicotine.Biol Psychiatry 49, no. 3 (February 1, 2001): 258–67. https://doi.org/10.1016/s0006-3223(00)01094-5.
Rezvani AH, Levin ED. Cognitive effects of nicotine. Biol Psychiatry. 2001 Feb 1;49(3):258–67.
Rezvani, A. H., and E. D. Levin. “Cognitive effects of nicotine.Biol Psychiatry, vol. 49, no. 3, Feb. 2001, pp. 258–67. Pubmed, doi:10.1016/s0006-3223(00)01094-5.
Rezvani AH, Levin ED. Cognitive effects of nicotine. Biol Psychiatry. 2001 Feb 1;49(3):258–267.
Journal cover image

Published In

Biol Psychiatry

DOI

ISSN

0006-3223

Publication Date

February 1, 2001

Volume

49

Issue

3

Start / End Page

258 / 267

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Receptors, Nicotinic
  • Psychiatry
  • Nicotine
  • Neuropsychological Tests
  • Humans
  • Hippocampus
  • Cognition Disorders
  • Animals
  • Alzheimer Disease