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Caffeine effects on cardiovascular and neuroendocrine responses to acute psychosocial stress and their relationship to level of habitual caffeine consumption.

Publication ,  Journal Article
Lane, JD; Adcock, RA; Williams, RB; Kuhn, CM
Published in: Psychosom Med
1990

The effects of a moderate dose of caffeine on cardiovascular and neuroendocrine stress reactivity were examined in 25 healthy male subjects selected as habitual or light consumers of caffeine. Measurements were taken under resting conditions before and after administration of caffeine (3.5 mg/kg) or placebo, during a stressful laboratory task, and in a post-stress recovery period. Caffeine elevated blood pressure and plasma norepinephrine levels at rest, effects which added significantly to the effects of stress. Caffeine potentiated stress-related increases in plasma epinephrine and cortisol stress, more than doubling the responses observed in the control condition. These effects were present in both habitual and light consumers and level of habitual caffeine consumption did not affect their magnitude. Results indicate that caffeine can potentiate both cardiovascular and neuroendocrine stress reactivity and that the habitual use of caffeine is not necessarily associated with the development of tolerance to these effects.

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Published In

Psychosom Med

DOI

ISSN

0033-3174

Publication Date

1990

Volume

52

Issue

3

Start / End Page

320 / 336

Location

United States

Related Subject Headings

  • Stress, Psychological
  • Social Environment
  • Psychiatry
  • Norepinephrine
  • Male
  • Hydrocortisone
  • Humans
  • Heart Rate
  • Epinephrine
  • Drug Tolerance
 

Citation

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Lane, J. D., Adcock, R. A., Williams, R. B., & Kuhn, C. M. (1990). Caffeine effects on cardiovascular and neuroendocrine responses to acute psychosocial stress and their relationship to level of habitual caffeine consumption. Psychosom Med, 52(3), 320–336. https://doi.org/10.1097/00006842-199005000-00006
Lane, J. D., R. A. Adcock, R. B. Williams, and C. M. Kuhn. “Caffeine effects on cardiovascular and neuroendocrine responses to acute psychosocial stress and their relationship to level of habitual caffeine consumption.Psychosom Med 52, no. 3 (1990): 320–36. https://doi.org/10.1097/00006842-199005000-00006.
Lane, J. D., et al. “Caffeine effects on cardiovascular and neuroendocrine responses to acute psychosocial stress and their relationship to level of habitual caffeine consumption.Psychosom Med, vol. 52, no. 3, 1990, pp. 320–36. Pubmed, doi:10.1097/00006842-199005000-00006.

Published In

Psychosom Med

DOI

ISSN

0033-3174

Publication Date

1990

Volume

52

Issue

3

Start / End Page

320 / 336

Location

United States

Related Subject Headings

  • Stress, Psychological
  • Social Environment
  • Psychiatry
  • Norepinephrine
  • Male
  • Hydrocortisone
  • Humans
  • Heart Rate
  • Epinephrine
  • Drug Tolerance