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Enzymatic nanolithography of a self-assembled oligonucleotide monolayer on gold.

Publication ,  Journal Article
Hyun, J; Kim, J; Craig, SL; Chilkoti, A
Published in: Journal of the American Chemical Society
April 2004

This paper describes a simple strategy to biochemically manipulate a surface at the nanoscale by enzyme dip-pen nanolithography using an endonuclease (DNase I) that is directly patterned on a self-assembled monolayer presenting a terminal oligonucleotide. Physisorbed nanopatterns of DNase I carried out nanoscale enzymology at the surface creating oligonucleotide patterns with the fidelity of the patterned enzyme because of the affinity of the enzyme for the immobilized, oligonucleotide substrate.

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Published In

Journal of the American Chemical Society

DOI

EISSN

1520-5126

ISSN

0002-7863

Publication Date

April 2004

Volume

126

Issue

15

Start / End Page

4770 / 4771

Related Subject Headings

  • Oligonucleotides
  • Nanotechnology
  • Microscopy, Atomic Force
  • Gold
  • General Chemistry
  • Deoxyribonuclease I
  • 40 Engineering
  • 34 Chemical sciences
  • 03 Chemical Sciences
 

Citation

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Chicago
ICMJE
MLA
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Hyun, J., Kim, J., Craig, S. L., & Chilkoti, A. (2004). Enzymatic nanolithography of a self-assembled oligonucleotide monolayer on gold. Journal of the American Chemical Society, 126(15), 4770–4771. https://doi.org/10.1021/ja049956q
Hyun, Jinho, Jeonghan Kim, Stephen L. Craig, and Ashutosh Chilkoti. “Enzymatic nanolithography of a self-assembled oligonucleotide monolayer on gold.Journal of the American Chemical Society 126, no. 15 (April 2004): 4770–71. https://doi.org/10.1021/ja049956q.
Hyun J, Kim J, Craig SL, Chilkoti A. Enzymatic nanolithography of a self-assembled oligonucleotide monolayer on gold. Journal of the American Chemical Society. 2004 Apr;126(15):4770–1.
Hyun, Jinho, et al. “Enzymatic nanolithography of a self-assembled oligonucleotide monolayer on gold.Journal of the American Chemical Society, vol. 126, no. 15, Apr. 2004, pp. 4770–71. Epmc, doi:10.1021/ja049956q.
Hyun J, Kim J, Craig SL, Chilkoti A. Enzymatic nanolithography of a self-assembled oligonucleotide monolayer on gold. Journal of the American Chemical Society. 2004 Apr;126(15):4770–4771.
Journal cover image

Published In

Journal of the American Chemical Society

DOI

EISSN

1520-5126

ISSN

0002-7863

Publication Date

April 2004

Volume

126

Issue

15

Start / End Page

4770 / 4771

Related Subject Headings

  • Oligonucleotides
  • Nanotechnology
  • Microscopy, Atomic Force
  • Gold
  • General Chemistry
  • Deoxyribonuclease I
  • 40 Engineering
  • 34 Chemical sciences
  • 03 Chemical Sciences