Human lung air spaces: potential for MR imaging with hyperpolarized He-3.
Publication
, Journal Article
MacFall, JR; Charles, HC; Black, RD; Middleton, H; Swartz, JC; Saam, B; Driehuys, B; Erickson, C; Happer, W; Cates, GD; Johnson, GA; Ravin, CE
Published in: Radiology
August 1996
Two healthy volunteers who had inhaled approximately 0.75 L of laser-polarized helium-3 gas underwent magnetic resonance imaging at 1.5 T with fast gradient-echo pulse sequences and small flip angles ( < 10 degrees). Thick-section (20 mm) coronal images, time-course data (30 images collected every 1.8 seconds), and thin-section (6 mm) images were acquired. Subjects were able to breathe the gas (12% polarization) without difficulty. Thick-section images were of good quality and had a signal-to-noise ratio (S/N) of 32:1 near the surface coil and 16:1 farther away. The time images showed regional differences, which indicated potential value for quantitation. High-resolution images showed greater detail and a S/N of approximately 6:1.
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Published In
Radiology
DOI
ISSN
0033-8419
Publication Date
August 1996
Volume
200
Issue
2
Start / End Page
553 / 558
Location
United States
Related Subject Headings
- Nuclear Medicine & Medical Imaging
- Middle Aged
- Male
- Magnetic Resonance Imaging
- Lung
- Isotopes
- Image Enhancement
- Humans
- Helium
- Adult
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MacFall, J. R., Charles, H. C., Black, R. D., Middleton, H., Swartz, J. C., Saam, B., … Ravin, C. E. (1996). Human lung air spaces: potential for MR imaging with hyperpolarized He-3. Radiology, 200(2), 553–558. https://doi.org/10.1148/radiology.200.2.8685356
MacFall, J. R., H. C. Charles, R. D. Black, H. Middleton, J. C. Swartz, B. Saam, B. Driehuys, et al. “Human lung air spaces: potential for MR imaging with hyperpolarized He-3.” Radiology 200, no. 2 (August 1996): 553–58. https://doi.org/10.1148/radiology.200.2.8685356.
MacFall JR, Charles HC, Black RD, Middleton H, Swartz JC, Saam B, et al. Human lung air spaces: potential for MR imaging with hyperpolarized He-3. Radiology. 1996 Aug;200(2):553–8.
MacFall, J. R., et al. “Human lung air spaces: potential for MR imaging with hyperpolarized He-3.” Radiology, vol. 200, no. 2, Aug. 1996, pp. 553–58. Pubmed, doi:10.1148/radiology.200.2.8685356.
MacFall JR, Charles HC, Black RD, Middleton H, Swartz JC, Saam B, Driehuys B, Erickson C, Happer W, Cates GD, Johnson GA, Ravin CE. Human lung air spaces: potential for MR imaging with hyperpolarized He-3. Radiology. 1996 Aug;200(2):553–558.
Published In
Radiology
DOI
ISSN
0033-8419
Publication Date
August 1996
Volume
200
Issue
2
Start / End Page
553 / 558
Location
United States
Related Subject Headings
- Nuclear Medicine & Medical Imaging
- Middle Aged
- Male
- Magnetic Resonance Imaging
- Lung
- Isotopes
- Image Enhancement
- Humans
- Helium
- Adult