Acute allograft rejection: cellular and humoral processes.
Publication
, Journal Article
Martinu, T; Pavlisko, EN; Chen, D-F; Palmer, SM
Published in: Clin Chest Med
June 2011
Acute cellular rejection affects greater than one-third of lung transplant recipients. Alloreactive T-lymphocytes constitute the basis of lung allograft rejection. Recent evidence supports a more complex immune response to the allograft. Interaction between recipient genetics, immunosuppression therapies, and allograft environmental exposures likely contribute to high rejection rates after lung transplantation. A greater understanding of the heterogeneous mechanisms of lung rejection is critical to developing effective therapies that target the precise pathophysiology of the disease and ultimately improve long-term lung transplant outcomes.
Duke Scholars
Published In
Clin Chest Med
DOI
EISSN
1557-8216
Publication Date
June 2011
Volume
32
Issue
2
Start / End Page
295 / 310
Location
United States
Related Subject Headings
- Transplantation, Homologous
- Transplantation Immunology
- Risk Factors
- Respiratory System
- Lung Transplantation
- Immunity, Humoral
- Immunity, Cellular
- Humans
- Graft Rejection
- Acute Disease
Citation
APA
Chicago
ICMJE
MLA
NLM
Martinu, T., Pavlisko, E. N., Chen, D.-F., & Palmer, S. M. (2011). Acute allograft rejection: cellular and humoral processes. Clin Chest Med, 32(2), 295–310. https://doi.org/10.1016/j.ccm.2011.02.008
Martinu, Tereza, Elizabeth N. Pavlisko, Dong-Feng Chen, and Scott M. Palmer. “Acute allograft rejection: cellular and humoral processes.” Clin Chest Med 32, no. 2 (June 2011): 295–310. https://doi.org/10.1016/j.ccm.2011.02.008.
Martinu T, Pavlisko EN, Chen D-F, Palmer SM. Acute allograft rejection: cellular and humoral processes. Clin Chest Med. 2011 Jun;32(2):295–310.
Martinu, Tereza, et al. “Acute allograft rejection: cellular and humoral processes.” Clin Chest Med, vol. 32, no. 2, June 2011, pp. 295–310. Pubmed, doi:10.1016/j.ccm.2011.02.008.
Martinu T, Pavlisko EN, Chen D-F, Palmer SM. Acute allograft rejection: cellular and humoral processes. Clin Chest Med. 2011 Jun;32(2):295–310.
Published In
Clin Chest Med
DOI
EISSN
1557-8216
Publication Date
June 2011
Volume
32
Issue
2
Start / End Page
295 / 310
Location
United States
Related Subject Headings
- Transplantation, Homologous
- Transplantation Immunology
- Risk Factors
- Respiratory System
- Lung Transplantation
- Immunity, Humoral
- Immunity, Cellular
- Humans
- Graft Rejection
- Acute Disease