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Corneal biometry from volumetric SDOCT and comparison with existing clinical modalities.

Publication ,  Journal Article
Kuo, AN; McNabb, RP; Zhao, M; Larocca, F; Stinnett, SS; Farsiu, S; Izatt, JA
Published in: Biomed Opt Express
June 1, 2012

We present a comparison of corneal biometric values from dense volumetric spectral domain optical coherence tomography (SDOCT) scans to reference values in both phantoms and clinical subjects. We also present a new optically based "keratometric equivalent power" formula for SDOCT that eliminates previously described discrepancies between corneal power form SDOCT and existing clinical modalities. Phantom objects of varying radii of curvature and corneas of normal subjects were imaged with a clinical SDOCT system. The optically corrected three-dimensional surfaces were used to recover radii of curvature and power as appropriate. These were then compared to the manufacturer's reference values in phantoms and to measurements from topography and Scheimpflug photography in subjects. In phantom objects, paired differences between SDOCT and reference values for radii of curvature were not statistically significant. In subjects, there were no significant paired differences between SDOCT and reference values from the other modalities for anterior radius and corneal keratometric power. In contrast to other studies, we found that dense volumetric scans with available SDOCT can be used to recover corneal biometric values-including power-that correspond well with existing clinical measurements.

Duke Scholars

Published In

Biomed Opt Express

DOI

EISSN

2156-7085

Publication Date

June 1, 2012

Volume

3

Issue

6

Start / End Page

1279 / 1290

Location

United States

Related Subject Headings

  • 5102 Atomic, molecular and optical physics
  • 4003 Biomedical engineering
  • 3212 Ophthalmology and optometry
  • 0912 Materials Engineering
  • 0205 Optical Physics
 

Citation

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ICMJE
MLA
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Kuo, A. N., McNabb, R. P., Zhao, M., Larocca, F., Stinnett, S. S., Farsiu, S., & Izatt, J. A. (2012). Corneal biometry from volumetric SDOCT and comparison with existing clinical modalities. Biomed Opt Express, 3(6), 1279–1290. https://doi.org/10.1364/BOE.3.001279
Kuo, Anthony N., Ryan P. McNabb, Mingtao Zhao, Francesco Larocca, Sandra S. Stinnett, Sina Farsiu, and Joseph A. Izatt. “Corneal biometry from volumetric SDOCT and comparison with existing clinical modalities.Biomed Opt Express 3, no. 6 (June 1, 2012): 1279–90. https://doi.org/10.1364/BOE.3.001279.
Kuo AN, McNabb RP, Zhao M, Larocca F, Stinnett SS, Farsiu S, et al. Corneal biometry from volumetric SDOCT and comparison with existing clinical modalities. Biomed Opt Express. 2012 Jun 1;3(6):1279–90.
Kuo, Anthony N., et al. “Corneal biometry from volumetric SDOCT and comparison with existing clinical modalities.Biomed Opt Express, vol. 3, no. 6, June 2012, pp. 1279–90. Pubmed, doi:10.1364/BOE.3.001279.
Kuo AN, McNabb RP, Zhao M, Larocca F, Stinnett SS, Farsiu S, Izatt JA. Corneal biometry from volumetric SDOCT and comparison with existing clinical modalities. Biomed Opt Express. 2012 Jun 1;3(6):1279–1290.
Journal cover image

Published In

Biomed Opt Express

DOI

EISSN

2156-7085

Publication Date

June 1, 2012

Volume

3

Issue

6

Start / End Page

1279 / 1290

Location

United States

Related Subject Headings

  • 5102 Atomic, molecular and optical physics
  • 4003 Biomedical engineering
  • 3212 Ophthalmology and optometry
  • 0912 Materials Engineering
  • 0205 Optical Physics