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Generalized papular xanthomatosis in mycosis fungoides.

Publication ,  Journal Article
Darwin, BS; Herzberg, AJ; Murray, JC; Olsen, EA
Published in: J Am Acad Dermatol
May 1992

Xanthomas can occur in association with underlying lymphoproliferative disease, or they can result from lipid deposition in damaged or altered skin. We report a case of generalized papular xanthomas that developed in a patient with Sézary syndrome. The xanthomas were composed of foamy histiocytes that were shown by immunoperoxidase staining to be of the monocyte/macrophage lineage. Electron microscopic studies revealed lipid vacuoles, lysosomes, and myelin figures but no Birbeck granules, features that are consistent with a non-X histiocytosis. Generalized papular xanthomatosis has not been previously described in a patient with cutaneous T-cell lymphoma.

Duke Scholars

Published In

J Am Acad Dermatol

DOI

ISSN

0190-9622

Publication Date

May 1992

Volume

26

Issue

5 Pt 2

Start / End Page

828 / 832

Location

United States

Related Subject Headings

  • Xanthomatosis
  • Staining and Labeling
  • Skin Neoplasms
  • Skin
  • Sezary Syndrome
  • Microscopy, Electron
  • Humans
  • Histiocytes
  • Female
  • Dermatology & Venereal Diseases
 

Citation

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Darwin, B. S., Herzberg, A. J., Murray, J. C., & Olsen, E. A. (1992). Generalized papular xanthomatosis in mycosis fungoides. J Am Acad Dermatol, 26(5 Pt 2), 828–832. https://doi.org/10.1016/0190-9622(92)70115-v
Darwin, B. S., A. J. Herzberg, J. C. Murray, and E. A. Olsen. “Generalized papular xanthomatosis in mycosis fungoides.J Am Acad Dermatol 26, no. 5 Pt 2 (May 1992): 828–32. https://doi.org/10.1016/0190-9622(92)70115-v.
Darwin BS, Herzberg AJ, Murray JC, Olsen EA. Generalized papular xanthomatosis in mycosis fungoides. J Am Acad Dermatol. 1992 May;26(5 Pt 2):828–32.
Darwin, B. S., et al. “Generalized papular xanthomatosis in mycosis fungoides.J Am Acad Dermatol, vol. 26, no. 5 Pt 2, May 1992, pp. 828–32. Pubmed, doi:10.1016/0190-9622(92)70115-v.
Darwin BS, Herzberg AJ, Murray JC, Olsen EA. Generalized papular xanthomatosis in mycosis fungoides. J Am Acad Dermatol. 1992 May;26(5 Pt 2):828–832.
Journal cover image

Published In

J Am Acad Dermatol

DOI

ISSN

0190-9622

Publication Date

May 1992

Volume

26

Issue

5 Pt 2

Start / End Page

828 / 832

Location

United States

Related Subject Headings

  • Xanthomatosis
  • Staining and Labeling
  • Skin Neoplasms
  • Skin
  • Sezary Syndrome
  • Microscopy, Electron
  • Humans
  • Histiocytes
  • Female
  • Dermatology & Venereal Diseases