
Generalized papular xanthomatosis in mycosis fungoides.
Publication
, Journal Article
Darwin, BS; Herzberg, AJ; Murray, JC; Olsen, EA
Published in: J Am Acad Dermatol
May 1992
Xanthomas can occur in association with underlying lymphoproliferative disease, or they can result from lipid deposition in damaged or altered skin. We report a case of generalized papular xanthomas that developed in a patient with Sézary syndrome. The xanthomas were composed of foamy histiocytes that were shown by immunoperoxidase staining to be of the monocyte/macrophage lineage. Electron microscopic studies revealed lipid vacuoles, lysosomes, and myelin figures but no Birbeck granules, features that are consistent with a non-X histiocytosis. Generalized papular xanthomatosis has not been previously described in a patient with cutaneous T-cell lymphoma.
Duke Scholars
Published In
J Am Acad Dermatol
DOI
ISSN
0190-9622
Publication Date
May 1992
Volume
26
Issue
5 Pt 2
Start / End Page
828 / 832
Location
United States
Related Subject Headings
- Xanthomatosis
- Staining and Labeling
- Skin Neoplasms
- Skin
- Sezary Syndrome
- Microscopy, Electron
- Humans
- Histiocytes
- Female
- Dermatology & Venereal Diseases
Citation
APA
Chicago
ICMJE
MLA
NLM
Darwin, B. S., Herzberg, A. J., Murray, J. C., & Olsen, E. A. (1992). Generalized papular xanthomatosis in mycosis fungoides. J Am Acad Dermatol, 26(5 Pt 2), 828–832. https://doi.org/10.1016/0190-9622(92)70115-v
Darwin, B. S., A. J. Herzberg, J. C. Murray, and E. A. Olsen. “Generalized papular xanthomatosis in mycosis fungoides.” J Am Acad Dermatol 26, no. 5 Pt 2 (May 1992): 828–32. https://doi.org/10.1016/0190-9622(92)70115-v.
Darwin BS, Herzberg AJ, Murray JC, Olsen EA. Generalized papular xanthomatosis in mycosis fungoides. J Am Acad Dermatol. 1992 May;26(5 Pt 2):828–32.
Darwin, B. S., et al. “Generalized papular xanthomatosis in mycosis fungoides.” J Am Acad Dermatol, vol. 26, no. 5 Pt 2, May 1992, pp. 828–32. Pubmed, doi:10.1016/0190-9622(92)70115-v.
Darwin BS, Herzberg AJ, Murray JC, Olsen EA. Generalized papular xanthomatosis in mycosis fungoides. J Am Acad Dermatol. 1992 May;26(5 Pt 2):828–832.

Published In
J Am Acad Dermatol
DOI
ISSN
0190-9622
Publication Date
May 1992
Volume
26
Issue
5 Pt 2
Start / End Page
828 / 832
Location
United States
Related Subject Headings
- Xanthomatosis
- Staining and Labeling
- Skin Neoplasms
- Skin
- Sezary Syndrome
- Microscopy, Electron
- Humans
- Histiocytes
- Female
- Dermatology & Venereal Diseases