John Carroll Murray | Scholars@Duke

John Carroll Murray
Professor of Dermatology

My current clinic trials are examining how biologic therapies may control psoriasis. These trials are attempting to identify psoriasis patients not responding to TNF-antagonists and changing the biologic strategy to control psoriasis . Other trials are using new biologic agents, such as a monoclonal antibody to IL-22 to assess the efficacy and safety in treating psoriasis.
Our keloid clinic is a specialty clinic intended to study etiologies and treatmnet options for these disfiguring fibrotic tumors. At this time we do not have any trials active for keloids.
We have completed trials using topical antioxidants for UV protection form reactive oxygen species. Other trials have studies novel topical antifungal agents for onychomycosis ( laureth -4)

Current Appointments & Affiliations

Professor of Dermatology, Dermatology, Clinical Science Departments 2006

Contact Information

3339 Hosp South, Durham, NC 27710
Duke Box 2907, Durham, NC 27710
murra013@mc.duke.edu (919) 684-2393

Background
Education, Training, & Certifications
- M.D., Duke University 1977
Duke Appointment History
- Associate Professor of Dermatology in the Department of Medicine, Dermatology, Clinical Science Departments 1994 - 2006
- Associate Clinical Professor of Dermatology in the Department of Medicine, Dermatology, Clinical Science Departments 1994
- Assistant Professor of Medicine, Medicine, Clinical Science Departments 1983 - 1994
- Associate in the Department of Medicine, Medicine, Clinical Science Departments 1982 - 1983
Research
Selected Grants
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Murray, John C., James A. Burch, Robert D. Streilein, Mary Ann Iannacchione, Russell P. Hall, and Sheldon R. Pinnell. “A topical antioxidant solution containing vitamins C and E stabilized by ferulic acid provides protection for human skin against damage caused by ultraviolet irradiation.” J Am Acad Dermatol 59, no. 3 (September 2008): 418–25. https://doi.org/10.1016/j.jaad.2008.05.004.
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  - Fangman, William L., M Angelica Selim, and John C. Murray. “Diffuse hypopigmented macules.” Arch Dermatol 142, no. 2 (February 2006): 235–40. https://doi.org/10.1001/archderm.142.2.235-a.
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  - Stern, Robert S., and Robert S. PUVA Follow-up Study. “Inpatient hospital care for psoriasis: a vanishing practice in the United States.” J Am Acad Dermatol 49, no. 3 (September 2003): 445–50. https://doi.org/10.1067/s0190-9622(03)00858-2.
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  - Lucas, Chere R., Linda L. Sanders, John C. Murray, Sarah A. Myers, Russell P. Hall, and James M. Grichnik. “Early melanoma detection: nonuniform dermoscopic features and growth.” J Am Acad Dermatol 48, no. 5 (May 2003): 663–71. https://doi.org/10.1067/mjd.2003.283.
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  - DeBuys, H. V., S. B. Levy, J. C. Murray, D. L. Madey, and S. R. Pinnell. “Modern approaches to photoprotection.” Dermatol Clin 18, no. 4 (October 2000): 577–90. https://doi.org/10.1016/s0733-8635(05)70208-4.
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  - Stern, R. S., L. H. Väkevä, and L. H. PUVA Follow-up Study. “Noncutaneous malignant tumors in the PUVA follow-up study: 1975-1996.” J Invest Dermatol 108, no. 6 (June 1997): 897–900. https://doi.org/10.1111/1523-1747.ep12292698.
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  - Stern, R. S., and K. T. Nichols. “Therapy with orally administered methoxsalen and ultraviolet A radiation during childhood increases the risk of basal cell carcinoma. The PUVA Follow-up Study.” J Pediatr 129, no. 6 (December 1996): 915–17. https://doi.org/10.1016/s0022-3476(96)70039-2.
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  - Berg, D., J. A. Garcia, W. A. Schell, J. R. Perfect, and J. C. Murray. “Cutaneous infection caused by Curvularia pallescens: a case report and review of the spectrum of disease.” J Am Acad Dermatol 32, no. 2 Pt 2 (February 1995): 375–78. https://doi.org/10.1016/0190-9622(95)90408-5.
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  - Stern, R. S. “Ocular lens findings in patients treated with PUVA. Photochemotherapy Follow-Up-Study.” J Invest Dermatol 103, no. 4 (October 1994): 534–38. https://doi.org/10.1111/1523-1747.ep12395733.
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  - Darling, T. N., N. Sidhu-Malik, G. R. Corey, N. B. Allen, H. Kamino, and J. C. Murray. “Treatment of Mycobacterium haemophilum infection with an antibiotic regimen including clarithromycin.” Br J Dermatol 131, no. 3 (September 1994): 376–79. https://doi.org/10.1111/j.1365-2133.1994.tb08528.x.
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  - Murray, J. C. “Keloids and hypertrophic scars.” Clin Dermatol 12, no. 1 (January 1994): 27–37. https://doi.org/10.1016/0738-081x(94)90254-2.
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  - Murray, J. C. “Scars and keloids.” Dermatol Clin 11, no. 4 (October 1993): 697–708.
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  - Hall, R. P., J. C. Murray, M. M. McCord, M. J. Rico, and R. D. Streilein. “Rabbits immunized with a peptide encoded for by the 230-kD bullous pemphigoid antigen cDNA develop an enhanced inflammatory response to UVB irradiation: a potential animal model for bullous pemphigoid.” J Invest Dermatol 101, no. 1 (July 1993): 9–14. https://doi.org/10.1111/1523-1747.ep12358276.
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  - Russell, L. C., and J. Murray. “Patient education: recommendations regarding sunscreens, drugs, and diet.” Ann Plast Surg 28, no. 1 (January 1992): 14–16. https://doi.org/10.1097/00000637-199201000-00006.
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  - Blum, F., G. Gilkeson, C. Greenberg, and J. Murray. “Superficial migratory thrombophlebitis and the lupus anticoagulant.” Int J Dermatol 29, no. 3 (April 1990): 190–92. https://doi.org/10.1111/j.1365-4362.1990.tb03797.x.
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  - Murray, J. C. “Pregnancy and the skin.” Dermatol Clin 8, no. 2 (April 1990): 327–34.
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  - Fisher, S. R., G. V. Burton, J. C. Murray, M. Borowitz, and I. R. Crocker. “Primary cutaneous lymphoma of the head and neck.” Laryngoscope 96, no. 6 (June 1986): 653–55. https://doi.org/10.1288/00005537-198606000-00011.
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  - Pizzo, S. V., J. C. Murray, and S. L. Gonias. “Atrophie blanche. A disorder associated with defective release of tissue plasminogen activator.” Arch Pathol Lab Med 110, no. 6 (June 1986): 517–19.
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  - Patterson, J. W., M. Ali, J. C. Murray, and T. A. Hazra. “Bullous pemphigoid. Occurrence in a patient with mycosis fungoides receiving PUVA and topical nitrogen mustard therapy.” Int J Dermatol 24, no. 3 (April 1985): 173–76. https://doi.org/10.1111/j.1365-4362.1985.tb05751.x.
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  - Patterson, J. W., M. Ali, J. C. Murray, and J. A. Hazka. “Bullous Pemphigoid: Occurrence in a Patient with Mycosis Fungoides Receiving PUVA and Topical Nitrogen Mustard Therapy.” International Journal of Dermatology 24, no. 1 (January 1, 1985): 173–76. https://doi.org/10.1111/j.1365-4362.1985.tb05416.x.
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  - Murray, J. C., S. V. Pollack, and S. R. Pinnell. “Keloids and hypertrophic scars.” Clin Dermatol 2, no. 3 (July 1984): 121–33. https://doi.org/10.1016/0738-081x(84)90035-x.
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  - Gange, R. W., P. Levins, J. Murray, R. R. Anderson, and J. A. Parrish. “Prolonged skin photosensitization induced by methoxsalen and subphototoxic UVA irradiation.” J Invest Dermatol 82, no. 3 (March 1984): 219–22. https://doi.org/10.1111/1523-1747.ep12260043.
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  - Murray, J. C., R. S. Gilgor, and G. S. Lazarus. “Serum triglyceride elevation following high-dose vitamin A treatment for pityriasis rubra pilaris.” Arch Dermatol 119, no. 8 (August 1983): 675–76.
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  - Murray, J. C., S. V. Pollack, and S. R. Pinnell. “Keloids: a review.” J Am Acad Dermatol 4, no. 4 (April 1981): 461–70. https://doi.org/10.1016/s0190-9622(81)70048-3.
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  - Murray, J. C., K. A. Lindberg, and S. R. Pinnell. “In vitro inhibition of chick embryo lysyl hydroxylase by homogentisic acid. A proposed connective tissue defect in alkaptonuria.” J Clin Invest 59, no. 6 (June 1977): 1071–79. https://doi.org/10.1172/JCI108730.
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  - Murray, J. C., R. H. Cassell, and S. R. Pinnell. “Inhibition of lysyl hydroxylase by catechol analogs.” Biochim Biophys Acta 481, no. 1 (March 15, 1977): 63–70. https://doi.org/10.1016/0005-2744(77)90137-1.
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  - Murray, J. C., K. A. Lindberg, and S. R. Pinnell. “In vitro inhibition of collagen cross links by catechol analogs.” J Invest Dermatol 68, no. 3 (March 1977): 146–50. https://doi.org/10.1111/1523-1747.ep12492467.
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Education, Training, & Certifications

Duke Appointment History

Selected Grants

Selected Publications

Academic Articles