John Carroll Murray

My current clinic trials are examining how biologic therapies may control psoriasis. These trials are attempting to identify psoriasis patients not responding to TNF-antagonists and changing the biologic strategy to control psoriasis . Other trials are using new biologic agents, such as a monoclonal antibody to IL-22 to assess the efficacy and safety in treating psoriasis.
Our keloid clinic is a specialty clinic intended to study etiologies and treatmnet options for these disfiguring fibrotic tumors. At this time we do not have any trials active for keloids.
We have completed trials using topical antioxidants for UV protection form reactive oxygen species. Other trials have studies novel topical antifungal agents for onychomycosis ( laureth -4)

Current Appointments & Affiliations

Professor of Dermatology · 2006 - Present Dermatology, Clinical Science Departments

Recent Publications

Bilateral eccrine angiomatous hamartomas of the proximal interphalangeal joints.

Journal Article Dermatol Online J · April 15, 2023 Eccrine angiomatous hamartoma is an uncommon, benign clinical entity constituting a nodular proliferation of eccrine glands and vascular structures localized to the dermis that typically present as unilateral, flesh-colored, erythematous, or violaceous pap ... Full text Link to item Cite

A topical antioxidant solution containing vitamins C and E stabilized by ferulic acid provides protection for human skin against damage caused by ultraviolet irradiation.

Journal Article J Am Acad Dermatol · September 2008 BACKGROUND: Skin cancer and photoaging changes result from ultraviolet (UV)-induced oxidative stress. Topical antioxidants may protect skin from these effects. OBJECTIVE: We sought to determine whether a stable topical formulation of 15% L-ascorbic acid, 1 ... Full text Link to item Cite

Diffuse hypopigmented macules.

Journal Article Arch Dermatol · February 2006 Full text Link to item Cite

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Recent Grants

ESK-001-016 ONWARD1: A Multicenter, Randomized, Double-Blind, Placebo and Active Comparator Controlled Phase 3 Study to Evaluate the Efficacy and Safety of ESK-001 in Patients with Moderate to Severe Plaque Psoriasis

Clinical TrialPrincipal Investigator · Awarded by Alumis Inc. · 2024 - 2029

A Phase 3, Randomized, Multicenter, Double Blind, Placebo and Active Comparator-Controlled Study with a Randomized Withdrawal and Retreatment Period to Evaluate the Efficacy, Safety, and Tolerability of TAK-279 in subjects with moderate to severe

Clinical TrialPrincipal Investigator · Awarded by Takeda Development Center Americas, Inc · 2023 - 2026

Evaluation of the effect of moisturizers on the absorption of metronidazole and ivermectin into the stratum corneum of rosacea patients with tape stripping and liquid chromatography mass spectrometry

ResearchCo Investigator · Awarded by National Rosacea Society · 2023 - 2026

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Education, Training & Certifications

Duke University · 1977 M.D.