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Feasibility of non-invasive determination of the stability of propagation reserve in patients

Publication ,  Journal Article
Idriss, SF; Krassowska Neu, W; Varadarajan, V; Antonijevic, T; Gilani, SS; Starobin, JM
Published in: Computing in Cardiology
December 1, 2012

This study investigates the feasibility of using surface ECG recordings to assess stability of cardiac propagation. Our novel method customizes a reaction-diffusion model of cardiac excitation using measurements of patient's repolarization dynamics. The customized model determines the stability-of-propagation reserve (SoPR) that measures the proximity of the patient's minimum level of refractoriness to the critical level associated with conduction instability. Using measurements from 15 patients, we compared SoPRs determined from the unipolar intracardiac electrograms and from the surface ECG leads. SoPRs computed from intracardiac and surface measurements correlated, and a formula was developed that estimated the intracardiac SoPR from surface measurements with 5% accuracy. Thus, this study may lead to new noninvasive tests for the risk of sudden cardiac death. © 2012 CCAL.

Duke Scholars

Published In

Computing in Cardiology

EISSN

2325-887X

ISSN

2325-8861

Publication Date

December 1, 2012

Volume

39

Start / End Page

353 / 356
 

Citation

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Idriss, S. F., Krassowska Neu, W., Varadarajan, V., Antonijevic, T., Gilani, S. S., & Starobin, J. M. (2012). Feasibility of non-invasive determination of the stability of propagation reserve in patients. Computing in Cardiology, 39, 353–356.
Idriss, S. F., W. Krassowska Neu, V. Varadarajan, T. Antonijevic, S. S. Gilani, and J. M. Starobin. “Feasibility of non-invasive determination of the stability of propagation reserve in patients.” Computing in Cardiology 39 (December 1, 2012): 353–56.
Idriss SF, Krassowska Neu W, Varadarajan V, Antonijevic T, Gilani SS, Starobin JM. Feasibility of non-invasive determination of the stability of propagation reserve in patients. Computing in Cardiology. 2012 Dec 1;39:353–6.
Idriss, S. F., et al. “Feasibility of non-invasive determination of the stability of propagation reserve in patients.” Computing in Cardiology, vol. 39, Dec. 2012, pp. 353–56.
Idriss SF, Krassowska Neu W, Varadarajan V, Antonijevic T, Gilani SS, Starobin JM. Feasibility of non-invasive determination of the stability of propagation reserve in patients. Computing in Cardiology. 2012 Dec 1;39:353–356.

Published In

Computing in Cardiology

EISSN

2325-887X

ISSN

2325-8861

Publication Date

December 1, 2012

Volume

39

Start / End Page

353 / 356