Automatic cone photoreceptor segmentation using graph theory and dynamic programming.
Publication
, Journal Article
Chiu, SJ; Lokhnygina, Y; Dubis, AM; Dubra, A; Carroll, J; Izatt, JA; Farsiu, S
Published in: Biomed Opt Express
June 1, 2013
Geometrical analysis of the photoreceptor mosaic can reveal subclinical ocular pathologies. In this paper, we describe a fully automatic algorithm to identify and segment photoreceptors in adaptive optics ophthalmoscope images of the photoreceptor mosaic. This method is an extension of our previously described closed contour segmentation framework based on graph theory and dynamic programming (GTDP). We validated the performance of the proposed algorithm by comparing it to the state-of-the-art technique on a large data set consisting of over 200,000 cones and posted the results online. We found that the GTDP method achieved a higher detection rate, decreasing the cone miss rate by over a factor of five.
Duke Scholars
Published In
Biomed Opt Express
DOI
ISSN
2156-7085
Publication Date
June 1, 2013
Volume
4
Issue
6
Start / End Page
924 / 937
Location
United States
Related Subject Headings
- 5102 Atomic, molecular and optical physics
- 4003 Biomedical engineering
- 3212 Ophthalmology and optometry
- 0912 Materials Engineering
- 0205 Optical Physics
Citation
APA
Chicago
ICMJE
MLA
NLM
Chiu, S. J., Lokhnygina, Y., Dubis, A. M., Dubra, A., Carroll, J., Izatt, J. A., & Farsiu, S. (2013). Automatic cone photoreceptor segmentation using graph theory and dynamic programming. Biomed Opt Express, 4(6), 924–937. https://doi.org/10.1364/BOE.4.000924
Chiu, Stephanie J., Yuliya Lokhnygina, Adam M. Dubis, Alfredo Dubra, Joseph Carroll, Joseph A. Izatt, and Sina Farsiu. “Automatic cone photoreceptor segmentation using graph theory and dynamic programming.” Biomed Opt Express 4, no. 6 (June 1, 2013): 924–37. https://doi.org/10.1364/BOE.4.000924.
Chiu SJ, Lokhnygina Y, Dubis AM, Dubra A, Carroll J, Izatt JA, et al. Automatic cone photoreceptor segmentation using graph theory and dynamic programming. Biomed Opt Express. 2013 Jun 1;4(6):924–37.
Chiu, Stephanie J., et al. “Automatic cone photoreceptor segmentation using graph theory and dynamic programming.” Biomed Opt Express, vol. 4, no. 6, June 2013, pp. 924–37. Pubmed, doi:10.1364/BOE.4.000924.
Chiu SJ, Lokhnygina Y, Dubis AM, Dubra A, Carroll J, Izatt JA, Farsiu S. Automatic cone photoreceptor segmentation using graph theory and dynamic programming. Biomed Opt Express. 2013 Jun 1;4(6):924–937.
Published In
Biomed Opt Express
DOI
ISSN
2156-7085
Publication Date
June 1, 2013
Volume
4
Issue
6
Start / End Page
924 / 937
Location
United States
Related Subject Headings
- 5102 Atomic, molecular and optical physics
- 4003 Biomedical engineering
- 3212 Ophthalmology and optometry
- 0912 Materials Engineering
- 0205 Optical Physics