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The effects of femoral graft placement on cartilage thickness after anterior cruciate ligament reconstruction.

Publication ,  Journal Article
Okafor, EC; Utturkar, GM; Widmyer, MR; Abebe, ES; Collins, AT; Taylor, DC; Spritzer, CE; Moorman, CT; Garrett, WE; DeFrate, LE
Published in: J Biomech
January 3, 2014

Altered joint motion has been thought to be a contributing factor in the long-term development of osteoarthritis after ACL reconstruction. While many studies have quantified knee kinematics after ACL injury and reconstruction, there is limited in vivo data characterizing the effects of altered knee motion on cartilage thickness distributions. Thus, the objective of this study was to compare cartilage thickness distributions in two groups of patients with ACL reconstruction: one group in which subjects received a non-anatomic reconstruction that resulted in abnormal joint motion and another group in which subjects received an anatomically placed graft that more closely restored normal knee motion. Ten patients with anatomic graft placement (mean follow-up: 20 months) and 12 patients with non-anatomic graft placement (mean follow-up: 18 months) were scanned using high-resolution MR imaging. These images were used to generate 3D mesh models of both knees of each patient. The operative and contralateral knee models were registered to each other and a grid sampling system was used to make site-specific comparisons of cartilage thickness. Patients in the non-anatomic graft placement group demonstrated a significant decrease in cartilage thickness along the medial intercondylar notch in the operative knee relative to the intact knee (8%). In the anatomic graft placement group, no significant changes were observed. These findings suggest that restoring normal knee motion after ACL injury may help to slow the progression of degeneration. Therefore, graft placement may have important implications on the development of osteoarthritis after ACL reconstruction.

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Published In

J Biomech

DOI

EISSN

1873-2380

Publication Date

January 3, 2014

Volume

47

Issue

1

Start / End Page

96 / 101

Location

United States

Related Subject Headings

  • Young Adult
  • Plastic Surgery Procedures
  • Osteoarthritis
  • Movement
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging
  • Knee
  • Imaging, Three-Dimensional
  • Humans
 

Citation

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MLA
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Okafor, E. C., Utturkar, G. M., Widmyer, M. R., Abebe, E. S., Collins, A. T., Taylor, D. C., … DeFrate, L. E. (2014). The effects of femoral graft placement on cartilage thickness after anterior cruciate ligament reconstruction. J Biomech, 47(1), 96–101. https://doi.org/10.1016/j.jbiomech.2013.10.003
Okafor, Eziamaka C., Gangadhar M. Utturkar, Margaret R. Widmyer, Ermias S. Abebe, Amber T. Collins, Dean C. Taylor, Charles E. Spritzer, C. T. Moorman, William E. Garrett, and Louis E. DeFrate. “The effects of femoral graft placement on cartilage thickness after anterior cruciate ligament reconstruction.J Biomech 47, no. 1 (January 3, 2014): 96–101. https://doi.org/10.1016/j.jbiomech.2013.10.003.
Okafor EC, Utturkar GM, Widmyer MR, Abebe ES, Collins AT, Taylor DC, et al. The effects of femoral graft placement on cartilage thickness after anterior cruciate ligament reconstruction. J Biomech. 2014 Jan 3;47(1):96–101.
Okafor, Eziamaka C., et al. “The effects of femoral graft placement on cartilage thickness after anterior cruciate ligament reconstruction.J Biomech, vol. 47, no. 1, Jan. 2014, pp. 96–101. Pubmed, doi:10.1016/j.jbiomech.2013.10.003.
Okafor EC, Utturkar GM, Widmyer MR, Abebe ES, Collins AT, Taylor DC, Spritzer CE, Moorman CT, Garrett WE, DeFrate LE. The effects of femoral graft placement on cartilage thickness after anterior cruciate ligament reconstruction. J Biomech. 2014 Jan 3;47(1):96–101.
Journal cover image

Published In

J Biomech

DOI

EISSN

1873-2380

Publication Date

January 3, 2014

Volume

47

Issue

1

Start / End Page

96 / 101

Location

United States

Related Subject Headings

  • Young Adult
  • Plastic Surgery Procedures
  • Osteoarthritis
  • Movement
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging
  • Knee
  • Imaging, Three-Dimensional
  • Humans