Overview
Dr. Andrey Bortsov is an Assistant Professor in the Department of Anesthesiology and holds a faculty position in the Center for Translational Pain Medicine (CTPM). He earned his Doctor of Medicine degree (1999) from Pavlov State Medical University, Saint Petersburg, Russia, and his PhD in Epidemiology (2010) from the University of South Carolina at Columbia.
In 2010, he joined the faculty at UNC Department of Anesthesiology as a Research Assistant Professor, where he studied genetics and non-genetic risk factors of chronic pain development after traumatic stressful events. Dr. Bortsov has published more than 30 peer-reviewed articles and presented his work at major and national and international conferences.
Dr. Bortsov joined the faulty at Duke University in 2016, where he continues his work on pain genomics. His major area of interest is application of novel computational and statistical methods to big genomic datasets to develop prediction models for disease risk and treatment outcomes.
In 2010, he joined the faculty at UNC Department of Anesthesiology as a Research Assistant Professor, where he studied genetics and non-genetic risk factors of chronic pain development after traumatic stressful events. Dr. Bortsov has published more than 30 peer-reviewed articles and presented his work at major and national and international conferences.
Dr. Bortsov joined the faulty at Duke University in 2016, where he continues his work on pain genomics. His major area of interest is application of novel computational and statistical methods to big genomic datasets to develop prediction models for disease risk and treatment outcomes.
Current Duke Appointments & Affiliations
Assistant Professor in Anesthesiology
·
2021 - Present
Anesthesiology,
Clinical Science Departments
Recent Scholarly Works
Dynamic perioperative changes in baroreflex sensitivity predict postoperative pain.
Journal article Pain Med · April 1, 2026 OBJECTIVE: Although higher baroreflex sensitivity (BRS) is typically associated with reduced pain sensitivity, we previously reported that elevated preoperative BRS predicted greater postoperative pain after cardiothoracic surgery, a finding that challenge ... Full text Link to item CiteHow people resolve pain: insights from human transcriptomics into immune activation and therapeutic innovations.
Journal article Pain · November 1, 2025 Patients with chronic pain commonly exhibit elevated inflammatory markers in the blood that correlate with reported pain and pain-related disability. Although inflammation is traditionally seen as a driver of chronic pain, recent transcriptomic data challe ... Full text Link to item CiteBiological markers and psychosocial factors predict chronic pain conditions.
Journal article Nat Hum Behav · August 2025 Chronic pain is a multifactorial condition presenting significant diagnostic and prognostic challenges. Biomarkers for the classification and the prediction of chronic pain are therefore critically needed. Here, in this multidataset study of over 523,000 p ... Full text Link to item CiteRecent Grants
Targeting checkpoint inhibitors for pain control
ResearchCo Investigator · Awarded by National Institutes of Health · 2023 - 2027Identification and validation of LPA/LPAR signaling in temporomandibular disorder pain
ResearchCollaborator · Awarded by National Institutes of Health · 2024 - 2027Pain Management in Critical Combat Casualty Environments using Resorbable Poly(ester urea) Films for Sustained Delivery of Meloxicam and Bupivacaine
ResearchCo Investigator · Awarded by Department of Defense · 2022 - 2026View All Grants
Education
University of South Carolina, Columbia ·
2010
Ph.D.
St. Petersburg State University (Russia) ·
1999
M.D.