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Andrey V Bortsov

Assistant Professor in Anesthesiology
Anesthesiology

Overview


Dr. Andrey Bortsov is an Assistant Professor in the Department of Anesthesiology and holds a faculty position in the Center for Translational Pain Medicine (CTPM). He earned his Doctor of Medicine degree (1999) from Pavlov State Medical University, Saint Petersburg, Russia, and his PhD in Epidemiology (2010) from the University of South Carolina at Columbia.

In 2010, he joined the faculty at UNC Department of Anesthesiology as a Research Assistant Professor, where he studied genetics and non-genetic risk factors of chronic pain development after traumatic stressful events. Dr. Bortsov has published more than 30 peer-reviewed articles and presented his work at major and national and international conferences.

Dr. Bortsov joined the faulty at Duke University in 2016, where he continues his work on pain genomics. His major area of interest is application of novel computational and statistical methods to big genomic datasets to develop prediction models for disease risk and treatment outcomes.

Current Appointments & Affiliations


Assistant Professor in Anesthesiology · 2021 - Present Anesthesiology, Clinical Science Departments

Recent Publications


A mouse model of chronic primary pain that integrates clinically relevant genetic vulnerability, stress, and minor injury.

Journal Article Sci Transl Med · April 10, 2024 Chronic primary pain conditions (CPPCs) affect over 100 million Americans, predominantly women. They remain ineffectively treated, in large part because of a lack of valid animal models with translational relevance. Here, we characterized a CPPC mouse mode ... Full text Link to item Cite

Higher Cardiovagal Baroreflex Sensitivity Predicts Increased Pain Outcomes After Cardiothoracic Surgery.

Conference The journal of pain · January 2024 Excessive postoperative pain can lead to extended hospitalization and increased expenses, but factors that predict its severity are still unclear. Baroreceptor function could influence postoperative pain by modulating nociceptive processing and vagal-media ... Full text Cite

Biopsychosocial Factors Associated With Pain and Pain-Related Outcomes in Adults and Children With Sickle Cell Disease: A Multivariable Analysis of the GRNDaD Multicenter Registry.

Journal Article The journal of pain · January 2024 Pain is the primary symptomatic manifestation of sickle cell disease (SCD), an inherited hemoglobinopathy. The characteristics that influence pain experiences and outcomes in SCD are not fully understood. The primary objective of this study was to use mult ... Full text Cite
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Recent Grants


Predictors of Pain Severity and Pain-Related Outcomes in Individuals with Sickle Cell Disease

ResearchAdvisor · Awarded by National Heart, Lung, and Blood Institute · 2023 - 2028

Identification and validation of LPA/LPAR signaling in temporomandibular disorder pain

ResearchCollaborator · Awarded by National Institutes of Health · 2024 - 2027

Targeting checkpoint inhibitors for pain control

ResearchCo Investigator · Awarded by National Institutes of Health · 2023 - 2026

View All Grants