Journal ArticleNature communications · April 2025
Identifying cell types and states remains a time-consuming, error-prone challenge for spatial biology. While deep learning increasingly plays a role, it is difficult to generalize due to variability at the level of cells, neighborhoods, and niches in healt ...
Full textCite
Journal ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association · December 1, 2024
BACKGROUND: Single-cell technologies have revealed significant microglial cell heterogeneity across the human brain in both health and disease. However, the integration of high-plex protein and spatial information in single-cell approaches constitutes a ch ...
Full textCite
Other · November 15, 2024
<div>AbstractPurpose:<p>Androgen deprivation therapy (ADT) remains the backbone of prostate cancer treatment. Beyond the suppression of testosterone and tumor cell growth, emerging evidence suggests that ADT also modulates the immune tu ...
Full textCite