Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Ph.D., Duke University 2001
• Publications & Artistic Works
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  Selected Publications

  • Books

    • El Baidouri, Fouad, Polona Zalar, Timothy Y. James, Amy S. Gladfelter, and Anthony S. Amend. Evolution and Physiology of Amphibious Yeasts. Vol. 75, 2021. https://doi.org/10.1146/annurev-micro-051421-121352.
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    • Langdon, Erin M., and Amy S. Gladfelter. A New Lens for RNA Localization: Liquid-Liquid Phase Separation. Vol. 72, 2018. https://doi.org/10.1146/annurev-micro-090817-062814.
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    • Khan, Anum, Molly McQuilken, and Amy S. Gladfelter. Septins and Generation of Asymmetries in Fungal Cells. Vol. 69, 2015. https://doi.org/10.1146/annurev-micro-091014-104250.
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  • Academic Articles

    • Cannon, Kevin S., Jose M. Vargas-Muniz, Neil Billington, Ian Seim, Joanne Ekena, James R. Sellers, and Amy S. Gladfelter. “A gene duplication of a septin reveals a developmentally regulated filament length control mechanism.” J Cell Biol 222, no. 3 (March 6, 2023). https://doi.org/10.1083/jcb.202204063.
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    • Mayer, A. J., M. Roper, A. S. Gladfelter, and G. McLaughlin. “The role of RNA condensation in reducing gene expression noise.” Biophysical Journal 122, no. 3S1 (February 10, 2023): 415a-416a. https://doi.org/10.1016/j.bpj.2022.11.2256.
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    • Seim, I., A. J. Graham, A. Mathijssen, and A. S. Gladfelter. “RNA structure controls composition and network dynamics of condensates.” Biophysical Journal 122, no. 3S1 (February 10, 2023). https://doi.org/10.1016/j.bpj.2022.11.1670.
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    • Shi, Wenzheng, Kevin S. Cannon, Brandy N. Curtis, Christopher Edelmaier, Amy S. Gladfelter, and Ehssan Nazockdast. “Curvature sensing as an emergent property of multiscale assembly of septins.” Proc Natl Acad Sci U S A 120, no. 6 (February 7, 2023): e2208253120. https://doi.org/10.1073/pnas.2208253120.
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    • Jacobs, Katherine C., Amy S. Gladfelter, and Daniel J. Lew. “Targeted secretion: Myosin V delivers vesicles through formin condensates.” Curr Biol 32, no. 21 (November 7, 2022): R1228–31. https://doi.org/10.1016/j.cub.2022.10.001.
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    • Roden, Christine A., Yifan Dai, Catherine A. Giannetti, Ian Seim, Myungwoon Lee, Rachel Sealfon, Grace A. McLaughlin, et al. “Double-stranded RNA drives SARS-CoV-2 nucleocapsid protein to undergo phase separation at specific temperatures.” Nucleic Acids Res 50, no. 14 (August 12, 2022): 8168–92. https://doi.org/10.1093/nar/gkac596.
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    • Bartholomai, Bradley M., Amy S. Gladfelter, Jennifer J. Loros, and Jay C. Dunlap. “PRD-2 mediates clock-regulated perinuclear localization of clock gene RNAs within the circadian cycle of Neurospora.” Proc Natl Acad Sci U S A 119, no. 31 (August 2, 2022): e2203078119. https://doi.org/10.1073/pnas.2203078119.
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    • Curtis, Brandy N., Ellysa J. D. Vogt, Kevin S. Cannon, and Amy S. Gladfelter. “Reconstitution of Septin Assembly at Membranes to Study Biophysical Properties and Functions.” J Vis Exp, no. 185 (July 28, 2022). https://doi.org/10.3791/64090.
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    • Seim, Ian, Christine A. Roden, and Amy S. Gladfelter. “Role of spatial patterning of N-protein interactions in SARS-CoV-2 genome packaging.” Biophys J 121, no. 8 (April 19, 2022): 1580. https://doi.org/10.1016/j.bpj.2022.03.034.
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    • Snead, Wilton T., Ameya P. Jalihal, Therese M. Gerbich, Ian Seim, Zhongxiu Hu, and Amy S. Gladfelter. “Membrane surfaces regulate assembly of ribonucleoprotein condensates.” Nat Cell Biol 24, no. 4 (April 2022): 461–70. https://doi.org/10.1038/s41556-022-00882-3.
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    • Seim, Ian, Ammon E. Posey, Wilton T. Snead, Benjamin M. Stormo, Daphne Klotsa, Rohit V. Pappu, and Amy S. Gladfelter. “Dilute phase oligomerization can oppose phase separation and modulate material properties of a ribonucleoprotein condensate.” Proc Natl Acad Sci U S A 119, no. 13 (March 29, 2022): e2120799119. https://doi.org/10.1073/pnas.2120799119.
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    • Roden, Christine A., and Amy S. Gladfelter. “Design considerations for analyzing protein translation regulation by condensates.” Rna 28, no. 1 (January 2022): 88–96. https://doi.org/10.1261/rna.079002.121.
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    • Hiiragi, Takashi, Amy S. Gladfelter, Irene Miguel-Aliaga, Hilary A. Coller, On Sun Lau, Heidi M. McBride, Kazuhiro Aoki, et al. “20 years of Developmental Cell: Looking forward.” Dev Cell 56, no. 23 (December 6, 2021): 3185–91. https://doi.org/10.1016/j.devcel.2021.11.017.
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    • Bartholomai, Bradley M., Amy S. Gladfelter, Jennifer J. Loros, and Jay C. Dunlap. “Quantitative single molecule RNA-FISH and RNase-free cell wall digestion in Neurospora crassa.” Fungal Genet Biol 156 (November 2021): 103615. https://doi.org/10.1016/j.fgb.2021.103615.
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    • Woods, Benjamin L., Kevin S. Cannon, Ellysa J. D. Vogt, John M. Crutchley, and Amy S. Gladfelter. “Interplay of septin amphipathic helices in sensing membrane-curvature and filament bundling.” Mol Biol Cell 32, no. 20 (October 1, 2021): br5. https://doi.org/10.1091/mbc.E20-05-0303.
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    • Snead, Wilton T., and Amy S. Gladfelter. “Getting droplets into shape.” Science 373, no. 6560 (September 10, 2021): 1198–99. https://doi.org/10.1126/science.abl6282.
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    • Seim, Ian, Christine A. Roden, and Amy S. Gladfelter. “Role of spatial patterning of N-protein interactions in SARS-CoV-2 genome packaging.” Biophys J 120, no. 14 (July 20, 2021): 2771–84. https://doi.org/10.1016/j.bpj.2021.06.018.
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    • Lenne, Pierre-François, Edwin Munro, Idse Heemskerk, Aryeh Warmflash, Laura Bocanegra-Moreno, Kasumi Kishi, Anna Kicheva, et al. “Roadmap for the multiscale coupling of biochemical and mechanical signals during development.” Phys Biol 18, no. 4 (April 14, 2021). https://doi.org/10.1088/1478-3975/abd0db.
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    • Gerbich, Therese M., and Amy S. Gladfelter. “Moving beyond disease to function: Physiological roles for polyglutamine-rich sequences in cell decisions.” Curr Opin Cell Biol 69 (April 2021): 120–26. https://doi.org/10.1016/j.ceb.2021.01.003.
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    • Mitchison-Field, Lorna M. Y., and Amy S. Gladfelter. “Culturing and Multiplexed Time-Lapse Imaging of Fungal Isolates from Marine and Coastal Environments.” Curr Protoc 1, no. 4 (April 2021): e94. https://doi.org/10.1002/cpz1.94.
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    • Roden, Christine, and Amy S. Gladfelter. “RNA contributions to the form and function of biomolecular condensates.” Nat Rev Mol Cell Biol 22, no. 3 (March 2021): 183–95. https://doi.org/10.1038/s41580-020-0264-6.
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    • Yu, Haiyang, Shan Lu, Kelsey Gasior, Digvijay Singh, Sonia Vazquez-Sanchez, Olga Tapia, Divek Toprani, et al. “HSP70 chaperones RNA-free TDP-43 into anisotropic intranuclear liquid spherical shells.” Science 371, no. 6529 (February 5, 2021). https://doi.org/10.1126/science.abb4309.
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    • Woods, Benjamin L., and Amy S. Gladfelter. “The state of the septin cytoskeleton from assembly to function.” Curr Opin Cell Biol 68 (February 2021): 105–12. https://doi.org/10.1016/j.ceb.2020.10.007.
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    • Iserman, Christiane, Christine A. Roden, Mark A. Boerneke, Rachel S. G. Sealfon, Grace A. McLaughlin, Irwin Jungreis, Ethan J. Fritch, et al. “Genomic RNA Elements Drive Phase Separation of the SARS-CoV-2 Nucleocapsid.” Mol Cell 80, no. 6 (December 17, 2020): 1078-1091.e6. https://doi.org/10.1016/j.molcel.2020.11.041.
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    • Selbmann, L., Z. Benkő, C. Coleine, S. de Hoog, C. Donati, I. Druzhinina, T. Emri, et al. “Shed light in the dark lineages of the fungal tree of life—stres.” Life 10, no. 12 (December 1, 2020): 1–13. https://doi.org/10.3390/life10120362.
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    • Gasior, K., M. G. Forest, A. S. Gladfelter, and J. M. Newby. “Modeling the Mechanisms by Which Coexisting Biomolecular RNA-Protein Condensates Form.” Bull Math Biol 82, no. 12 (November 24, 2020): 153. https://doi.org/10.1007/s11538-020-00823-x.
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    • Jiao, Fang, Kevin S. Cannon, Yi-Chih Lin, Amy S. Gladfelter, and Simon Scheuring. “The hierarchical assembly of septins revealed by high-speed AFM.” Nat Commun 11, no. 1 (October 8, 2020): 5062. https://doi.org/10.1038/s41467-020-18778-x.
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    • Gerbich, Therese M., Grace A. McLaughlin, Katelyn Cassidy, Scott Gerber, David Adalsteinsson, and Amy S. Gladfelter. “Phosphoregulation provides specificity to biomolecular condensates in the cell cycle and cell polarity.” J Cell Biol 219, no. 7 (July 6, 2020). https://doi.org/10.1083/jcb.201910021.
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    • McLaughlin, Grace A., Erin M. Langdon, John M. Crutchley, Liam J. Holt, M Gregory Forest, Jay M. Newby, and Amy S. Gladfelter. “Spatial heterogeneity of the cytosol revealed by machine learning-based 3D particle tracking.” Mol Biol Cell 31, no. 14 (July 1, 2020): 1498–1511. https://doi.org/10.1091/mbc.E20-03-0210.
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    • Smith, Jean A., Ennessa G. Curry, R Eric Blue, Christine Roden, Samantha E. R. Dundon, Anthony Rodríguez-Vargas, Danielle C. Jordan, et al. “FXR1 splicing is important for muscle development and biomolecular condensates in muscle cells.” J Cell Biol 219, no. 4 (April 6, 2020). https://doi.org/10.1083/jcb.201911129.
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    • Johnson, Courtney R., Marc G. Steingesser, Andrew D. Weems, Anum Khan, Amy Gladfelter, Aurélie Bertin, and Michael A. McMurray. “Guanidine hydrochloride reactivates an ancient septin hetero-oligomer assembly pathway in budding yeast.” Elife 9 (January 28, 2020). https://doi.org/10.7554/eLife.54355.
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    • Mitchison-Field, Lorna M. Y., José M. Vargas-Muñiz, Benjamin M. Stormo, Ellysa J. D. Vogt, Sarah Van Dierdonck, James F. Pelletier, Christoph Ehrlich, Daniel J. Lew, Christine M. Field, and Amy S. Gladfelter. “Unconventional Cell Division Cycles from Marine-Derived Yeasts.” Curr Biol 29, no. 20 (October 21, 2019): 3439-3456.e5. https://doi.org/10.1016/j.cub.2019.08.050.
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    • Snead, Wilton T., and Amy S. Gladfelter. “The Control Centers of Biomolecular Phase Separation: How Membrane Surfaces, PTMs, and Active Processes Regulate Condensation.” Mol Cell 76, no. 2 (October 17, 2019): 295–305. https://doi.org/10.1016/j.molcel.2019.09.016.
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    • Cannon, Kevin S., Benjamin L. Woods, John M. Crutchley, and Amy S. Gladfelter. “An amphipathic helix enables septins to sense micrometer-scale membrane curvature.” J Cell Biol 218, no. 4 (April 1, 2019): 1128–37. https://doi.org/10.1083/jcb.201807211.
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    • Li, Hongda, Laura Saucedo-Cuevas, Ling Yuan, Danica Ross, Anide Johansen, Daniel Sands, Valentina Stanley, et al. “Zika Virus Protease Cleavage of Host Protein Septin-2 Mediates Mitotic Defects in Neural Progenitors.” Neuron 101, no. 6 (March 20, 2019): 1089-1098.e4. https://doi.org/10.1016/j.neuron.2019.01.010.
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    • Gladfelter, Amy S., Timothy Y. James, and Anthony S. Amend. “Marine fungi.” Curr Biol 29, no. 6 (March 18, 2019): R191–95. https://doi.org/10.1016/j.cub.2019.02.009.
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    • Amend, Anthony, Gaetan Burgaud, Michael Cunliffe, Virginia P. Edgcomb, Cassandra L. Ettinger, M. H. Gutiérrez, Joseph Heitman, et al. “Fungi in the Marine Environment: Open Questions and Unsolved Problems.” Mbio 10, no. 2 (March 5, 2019). https://doi.org/10.1128/mBio.01189-18.
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    • Alberti, Simon, Amy Gladfelter, and Tanja Mittag. “Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates.” Cell 176, no. 3 (January 24, 2019): 419–34. https://doi.org/10.1016/j.cell.2018.12.035.
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    • Gasior, Kelsey, Jia Zhao, Grace McLaughlin, M Gregory Forest, Amy S. Gladfelter, and Jay Newby. “Partial demixing of RNA-protein complexes leads to intradroplet patterning in phase-separated biological condensates.” Phys Rev E 99, no. 1–1 (January 2019): 012411. https://doi.org/10.1103/PhysRevE.99.012411.
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    • Garcia, Hernan G., Dirk Benzinger, Marc Rullan, Andreas Milias-Argeitis, Mustafa Khammash, Adam M. Deutschbauer, Erin M. Langdon, and Amy S. Gladfelter. “Principles of Systems Biology, No. 30.” Cell Syst 7, no. 1 (July 25, 2018): 1–2. https://doi.org/10.1016/j.cels.2018.07.002.
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    • Langdon, Erin M., Yupeng Qiu, Amirhossein Ghanbari Niaki, Grace A. McLaughlin, Chase A. Weidmann, Therese M. Gerbich, Jean A. Smith, et al. “mRNA structure determines specificity of a polyQ-driven phase separation.” Science 360, no. 6391 (May 25, 2018): 922–27. https://doi.org/10.1126/science.aar7432.
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    • Fadero, Tanner C., Therese M. Gerbich, Kishan Rana, Aussie Suzuki, Matthew DiSalvo, Kristina N. Schaefer, Jennifer K. Heppert, et al. “LITE microscopy: Tilted light-sheet excitation of model organisms offers high resolution and low photobleaching.” J Cell Biol 217, no. 5 (May 7, 2018): 1869–82. https://doi.org/10.1083/jcb.201710087.
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    • Khan, Anum, Jay Newby, and Amy S. Gladfelter. “Control of septin filament flexibility and bundling by subunit composition and nucleotide interactions.” Mol Biol Cell 29, no. 6 (March 15, 2018): 702–12. https://doi.org/10.1091/mbc.E17-10-0608.
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    • Cannon, Kevin S., Benjamin L. Woods, and Amy S. Gladfelter. “The Unsolved Problem of How Cells Sense Micron-Scale Curvature.” Trends Biochem Sci 42, no. 12 (December 2017): 961–76. https://doi.org/10.1016/j.tibs.2017.10.001.
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    • Smith, Jean A., and Amy S. Gladfelter. “Lessons from Yeast on How to Avoid Stress Eating.” Dev Cell 43, no. 1 (October 9, 2017): 3–5. https://doi.org/10.1016/j.devcel.2017.09.015.
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    • Gladfelter, Amy S., and Mark Peifer. “What your PI forgot to tell you: why you actually might want a job running a research lab.” Mol Biol Cell 28, no. 13 (July 1, 2017): 1724–27. https://doi.org/10.1091/mbc.E17-02-0091.
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    • Russell, James J., Julie A. Theriot, Pranidhi Sood, Wallace F. Marshall, Laura F. Landweber, Lillian Fritz-Laylin, Jessica K. Polka, et al. “Non-model model organisms.” Bmc Biol 15, no. 1 (June 29, 2017): 55. https://doi.org/10.1186/s12915-017-0391-5.
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    • McQuilken, M., M. S. Jentzsch, A. Verma, S. B. Mehta, R. Oldenbourg, and A. S. Gladfelter. “Analysis of septin reorganization at cytokinesis using polarized fluorescence microscopy.” Frontiers in Cell and Developmental Biology 5, no. MAY (May 3, 2017). https://doi.org/10.3389/fcell.2017.00042.
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    • Bridges, Andrew A., and Amy S. Gladfelter. “Septin complexes assemble during a kinetic window of opportunity.” Cell Cycle 15, no. 21 (November 2016): 2858–59. https://doi.org/10.1080/15384101.2016.1215700.
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    • Mehta, Shalin B., Molly McQuilken, Patrick J. La Riviere, Patricia Occhipinti, Amitabh Verma, Rudolf Oldenbourg, Amy S. Gladfelter, and Tomomi Tani. “Dissection of molecular assembly dynamics by tracking orientation and position of single molecules in live cells.” Proc Natl Acad Sci U S A 113, no. 42 (October 18, 2016): E6352–61. https://doi.org/10.1073/pnas.1607674113.
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    • Dundon, Samantha E. R., Shyr-Shea Chang, Abhishek Kumar, Patricia Occhipinti, Hari Shroff, Marcus Roper, and Amy S. Gladfelter. “Clustered nuclei maintain autonomy and nucleocytoplasmic ratio control in a syncytium.” Mol Biol Cell 27, no. 13 (July 1, 2016): 2000–2007. https://doi.org/10.1091/mbc.E16-02-0129.
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    • Bridges, Andrew A., Maximilian S. Jentzsch, Patrick W. Oakes, Patricia Occhipinti, and Amy S. Gladfelter. “Micron-scale plasma membrane curvature is recognized by the septin cytoskeleton.” J Cell Biol 213, no. 1 (April 11, 2016): 23–32. https://doi.org/10.1083/jcb.201512029.
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    • Lee, ChangHwan, Samantha E. Roberts, and Amy S. Gladfelter. “Quantitative spatial analysis of transcripts in multinucleate cells using single-molecule FISH.” Methods 98 (April 1, 2016): 124–33. https://doi.org/10.1016/j.ymeth.2015.12.007.
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    • Bridges, A. A., and A. S. Gladfelter. “In vitro reconstitution of septin assemblies on supported lipid bilayers.” Methods Cell Biol 136 (2016): 57–71. https://doi.org/10.1016/bs.mcb.2016.03.025.
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    • Roberts, Samantha E., and Amy S. Gladfelter. “Nuclear autonomy in multinucleate fungi.” Curr Opin Microbiol 28 (December 2015): 60–65. https://doi.org/10.1016/j.mib.2015.08.009.
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    • Gladfelter, Amy S. “How nontraditional model systems can save us.” Mol Biol Cell 26, no. 21 (November 1, 2015): 3687–89. https://doi.org/10.1091/mbc.E15-06-0429.
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    • Zhang, Huaiying, Shana Elbaum-Garfinkle, Erin M. Langdon, Nicole Taylor, Patricia Occhipinti, Andrew A. Bridges, Clifford P. Brangwynne, and Amy S. Gladfelter. “RNA Controls PolyQ Protein Phase Transitions.” Mol Cell 60, no. 2 (October 15, 2015): 220–30. https://doi.org/10.1016/j.molcel.2015.09.017.
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    • Hogan, Deborah A., and Amy S. Gladfelter. “Editorial overview: host-microbe interactions: fungi: heterogeneity in fungal cells, populations, and communities.” Curr Opin Microbiol 26 (August 2015): vii–ix. https://doi.org/10.1016/j.mib.2015.07.003.
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    • Roper, Marcus, ChangHwan Lee, Patrick C. Hickey, and Amy S. Gladfelter. “Life as a moving fluid: fate of cytoplasmic macromolecules in dynamic fungal syncytia.” Curr Opin Microbiol 26 (August 2015): 116–22. https://doi.org/10.1016/j.mib.2015.07.001.
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    • Bridges, Andrew A., and Amy S. Gladfelter. “Septin Form and Function at the Cell Cortex.” J Biol Chem 290, no. 28 (July 10, 2015): 17173–80. https://doi.org/10.1074/jbc.R114.634444.
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    • Kaplan, Charlotte, Bo Jing, Christian M. Winterflood, Andrew A. Bridges, Patricia Occhipinti, Jürgen Schmied, Sören Grinhagens, et al. “Absolute Arrangement of Subunits in Cytoskeletal Septin Filaments in Cells Measured by Fluorescence Microscopy.” Nano Lett 15, no. 6 (June 10, 2015): 3859–64. https://doi.org/10.1021/acs.nanolett.5b00693.
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    • McQuilken, Molly, Shalin B. Mehta, Amitabh Verma, Grant Harris, Rudolf Oldenbourg, and Amy S. Gladfelter. “Polarized Fluorescence Microscopy to Study Cytoskeleton Assembly and Organization in Live Cells.” Curr Protoc Cell Biol 67 (June 1, 2015): 4.29.1-4.29.13. https://doi.org/10.1002/0471143030.cb0429s67.
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    • Bezanilla, Magdalena, Amy S. Gladfelter, David R. Kovar, and Wei-Lih Lee. “Cytoskeletal dynamics: a view from the membrane.” J Cell Biol 209, no. 3 (May 11, 2015): 329–37. https://doi.org/10.1083/jcb.201502062.
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    • Dasgupta, Arko, Chen-Hui Chen, ChangHwan Lee, Amy S. Gladfelter, Jay C. Dunlap, and Jennifer J. Loros. “Biological Significance of Photoreceptor Photocycle Length: VIVID Photocycle Governs the Dynamic VIVID-White Collar Complex Pool Mediating Photo-adaptation and Response to Changes in Light Intensity.” Plos Genet 11, no. 5 (May 2015): e1005215. https://doi.org/10.1371/journal.pgen.1005215.
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    • Abrahamsson, Sara, Molly McQuilken, Shalin B. Mehta, Amitabh Verma, Johannes Larsch, Rob Ilic, Rainer Heintzmann, Cornelia I. Bargmann, Amy S. Gladfelter, and Rudolf Oldenbourg. “MultiFocus Polarization Microscope (MF-PolScope) for 3D polarization imaging of up to 25 focal planes simultaneously.” Opt Express 23, no. 6 (March 23, 2015): 7734–54. https://doi.org/10.1364/OE.23.007734.
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    • Anderson, Cori A., Samantha Roberts, Huaiying Zhang, Courtney M. Kelly, Alexxy Kendall, ChangHwan Lee, John Gerstenberger, Aaron B. Koenig, Ruth Kabeche, and Amy S. Gladfelter. “Ploidy variation in multinucleate cells changes under stress.” Mol Biol Cell 26, no. 6 (March 15, 2015): 1129–40. https://doi.org/10.1091/mbc.E14-09-1375.
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    • Lee, ChangHwan, Patricia Occhipinti, and Amy S. Gladfelter. “PolyQ-dependent RNA-protein assemblies control symmetry breaking.” J Cell Biol 208, no. 5 (March 2, 2015): 533–44. https://doi.org/10.1083/jcb.201407105.
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    • Bridges, Andrew A., and Amy S. Gladfelter. “Fungal pathogens are platforms for discovering novel and conserved septin properties.” Curr Opin Microbiol 20 (August 2014): 42–48. https://doi.org/10.1016/j.mib.2014.04.004.
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    • Gladfelter, Amy S. “Cytoskeleton: cirque du septins.” Curr Biol 24, no. 11 (June 2, 2014): R526–28. https://doi.org/10.1016/j.cub.2014.04.030.
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    • Bridges, Andrew A., Huaiying Zhang, Shalin B. Mehta, Patricia Occhipinti, Tomomi Tani, and Amy S. Gladfelter. “Septin assemblies form by diffusion-driven annealing on membranes.” Proc Natl Acad Sci U S A 111, no. 6 (February 11, 2014): 2146–51. https://doi.org/10.1073/pnas.1314138111.
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    • Anderson, Cori A., Umut Eser, Therese Korndorf, Mark E. Borsuk, Jan M. Skotheim, and Amy S. Gladfelter. “Nuclear repulsion enables division autonomy in a single cytoplasm.” Curr Biol 23, no. 20 (October 21, 2013): 1999–2010. https://doi.org/10.1016/j.cub.2013.07.076.
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    • Lee, Changhwan, Huaiying Zhang, Amy E. Baker, Patricia Occhipinti, Mark E. Borsuk, and Amy S. Gladfelter. “Protein aggregation behavior regulates cyclin transcript localization and cell-cycle control.” Dev Cell 25, no. 6 (June 24, 2013): 572–84. https://doi.org/10.1016/j.devcel.2013.05.007.
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    • Meseroll, Rebecca A., Patricia Occhipinti, and Amy S. Gladfelter. “Septin phosphorylation and coiled-coil domains function in cell and septin ring morphology in the filamentous fungus Ashbya gossypii.” Eukaryot Cell 12, no. 2 (February 2013): 182–93. https://doi.org/10.1128/EC.00251-12.
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    • Meseroll, Rebecca A., Louisa Howard, and Amy S. Gladfelter. “Septin ring size scaling and dynamics require the coiled-coil region of Shs1p.” Mol Biol Cell 23, no. 17 (September 2012): 3391–3406. https://doi.org/10.1091/mbc.E12-03-0207.
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    • Gerstenberger, John P., Patricia Occhipinti, and Amy S. Gladfelter. “Heterogeneity in mitochondrial morphology and membrane potential is independent of the nuclear division cycle in multinucleate fungal cells.” Eukaryot Cell 11, no. 3 (March 2012): 353–67. https://doi.org/10.1128/EC.05257-11.
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    • Spiliotis, Elias T., and Amy S. Gladfelter. “Spatial guidance of cell asymmetry: septin GTPases show the way.” Traffic 13, no. 2 (February 2012): 195–203. https://doi.org/10.1111/j.1600-0854.2011.01268.x.
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    • Anker, Jonathan F., and Amy S. Gladfelter. “Axl2 integrates polarity establishment, maintenance, and environmental stress response in the filamentous fungus Ashbya gossypii.” Eukaryot Cell 10, no. 12 (December 2011): 1679–93. https://doi.org/10.1128/EC.05183-11.
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    • DeMay, Bradley S., Naoki Noda, Amy S. Gladfelter, and Rudolf Oldenbourg. “Rapid and quantitative imaging of excitation polarized fluorescence reveals ordered septin dynamics in live yeast.” Biophys J 101, no. 4 (August 17, 2011): 985–94. https://doi.org/10.1016/j.bpj.2011.07.008.
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    • DeMay, Bradley S., Xiaobo Bai, Louisa Howard, Patricia Occhipinti, Rebecca A. Meseroll, Elias T. Spiliotis, Rudolf Oldenbourg, and Amy S. Gladfelter. “Septin filaments exhibit a dynamic, paired organization that is conserved from yeast to mammals.” J Cell Biol 193, no. 6 (June 13, 2011): 1065–81. https://doi.org/10.1083/jcb.201012143.
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    • Gladfelter, Amy S. “Guides to the final frontier of the cytoskeleton: septins in filamentous fungi.” Curr Opin Microbiol 13, no. 6 (December 2010): 720–26. https://doi.org/10.1016/j.mib.2010.09.012.
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    • Chen, Chen-Hui, Bradley S. DeMay, Amy S. Gladfelter, Jay C. Dunlap, and Jennifer J. Loros. “Physical interaction between VIVID and white collar complex regulates photoadaptation in Neurospora.” Proc Natl Acad Sci U S A 107, no. 38 (September 21, 2010): 16715–20. https://doi.org/10.1073/pnas.1011190107.
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    • Nair, Dhanalakshmi R., Cori A. D’Ausilio, Patricia Occhipinti, Mark E. Borsuk, and Amy S. Gladfelter. “A conserved G₁ regulatory circuit promotes asynchronous behavior of nuclei sharing a common cytoplasm.” Cell Cycle 9, no. 18 (September 15, 2010): 3771–79. https://doi.org/10.4161/cc.9.18.12999.
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    • Gladfelter, A. “Stuck in a checkpoint: A role for Ras deregulation in DNA damage checkpoint recovery.” Cell Cycle 9, no. 17 (September 1, 2010): 3398. https://doi.org/10.4161/cc.9.17.13071.
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    • DeMay, Bradley S., Rebecca A. Meseroll, Patricia Occhipinti, and Amy S. Gladfelter. “Cellular requirements for the small molecule forchlorfenuron to stabilize the septin cytoskeleton.” Cytoskeleton (Hoboken) 67, no. 6 (June 2010): 383–99. https://doi.org/10.1002/cm.20452.
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    • Gladfelter, Amy, and Judith Berman. “Dancing genomes: fungal nuclear positioning.” Nat Rev Microbiol 7, no. 12 (December 2009): 875–86. https://doi.org/10.1038/nrmicro2249.
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    • DeMay, Bradley S., Rebecca A. Meseroll, Patricia Occhipinti, and Amy S. Gladfelter. “Regulation of distinct septin rings in a single cell by Elm1p and Gin4p kinases.” Mol Biol Cell 20, no. 8 (April 2009): 2311–26. https://doi.org/10.1091/mbc.e08-12-1169.
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    • Sudbery, Peter E., and Amy S. Gladfelter. “Pathocycles.” Fungal Genet Biol 45, no. 1 (January 2008): 1–5. https://doi.org/10.1016/j.fgb.2007.02.009.
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    • Hungerbuehler, A Katrin, Peter Philippsen, and Amy S. Gladfelter. “Limited functional redundancy and oscillation of cyclins in multinucleated Ashbya gossypii fungal cells.” Eukaryot Cell 6, no. 3 (March 2007): 473–86. https://doi.org/10.1128/EC.00273-06.
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    • Gladfelter, Amy S., Nicoleta Sustreanu, A Katrin Hungerbuehler, Sylvia Voegeli, Virginie Galati, and Peter Philippsen. “The anaphase-promoting complex/cyclosome is required for anaphase progression in multinucleated Ashbya gossypii cells.” Eukaryot Cell 6, no. 2 (February 2007): 182–97. https://doi.org/10.1128/EC.00364-06.
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    • Gladfelter, Amy S. “Nuclear anarchy: asynchronous mitosis in multinucleated fungal hyphae.” Curr Opin Microbiol 9, no. 6 (December 2006): 547–52. https://doi.org/10.1016/j.mib.2006.09.002.
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    • Helfer, Hanspeter, and Amy S. Gladfelter. “AgSwe1p regulates mitosis in response to morphogenesis and nutrients in multinucleated Ashbya gossypii cells.” Mol Biol Cell 17, no. 10 (October 2006): 4494–4512. https://doi.org/10.1091/mbc.e06-03-0215.
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    • Gladfelter, A. S. “Erratum: Control of filamentous fungal cell shape by septins and formins (Nature Reviews Microbiology (2006) vol. 4 (223-229) 10.1038/nrmicro.1345).” Nature Reviews Microbiology 4, no. 4 (April 1, 2006): 318. https://doi.org/10.1038/nrmicro1402.
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    • Gladfelter, Amy S. “Control of filamentous fungal cell shape by septins and formins.” Nat Rev Microbiol 4, no. 3 (March 2006): 223–29. https://doi.org/10.1038/nrmicro1345.
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    • Gladfelter, Amy S., A Katrin Hungerbuehler, and Peter Philippsen. “Asynchronous nuclear division cycles in multinucleated cells.” J Cell Biol 172, no. 3 (January 30, 2006): 347–62. https://doi.org/10.1083/jcb.200507003.
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    • Gladfelter, Amy S., Lukasz Kozubowski, Trevin R. Zyla, and Daniel J. Lew. “Interplay between septin organization, cell cycle and cell shape in yeast.” J Cell Sci 118, no. Pt 8 (April 15, 2005): 1617–28. https://doi.org/10.1242/jcs.02286.
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    • Gladfelter, Amy S., Trevin R. Zyla, and Daniel J. Lew. “Genetic interactions among regulators of septin organization.” Eukaryot Cell 3, no. 4 (August 2004): 847–54. https://doi.org/10.1128/EC.3.4.847-854.2004.
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    • Irazoqui, Javier E., Amy S. Gladfelter, and Daniel J. Lew. “Cdc42p, GTP hydrolysis, and the cell's sense of direction.” Cell Cycle 3, no. 7 (July 2004): 861–64.
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    • Irazoqui, Javier E., Amy S. Gladfelter, and Daniel J. Lew. “Scaffold-mediated symmetry breaking by Cdc42p.” Nat Cell Biol 5, no. 12 (December 2003): 1062–70. https://doi.org/10.1038/ncb1068.
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    • Gladfelter, Amy S., Indrani Bose, Trevin R. Zyla, Elaine S. G. Bardes, and Daniel J. Lew. “Septin ring assembly involves cycles of GTP loading and hydrolysis by Cdc42p.” J Cell Biol 156, no. 2 (January 21, 2002): 315–26. https://doi.org/10.1083/jcb.200109062.
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    • Gladfelter, Amy. “A lab with a view: American postdocs abroad.” Cell Biol Educ 1, no. 4 (2002): 128–31. https://doi.org/10.1187/cbe.02-07-0015.
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    • Gladfelter, A. S., J. R. Pringle, and D. J. Lew. “The septin cortex at the yeast mother-bud neck.” Curr Opin Microbiol 4, no. 6 (December 2001): 681–89. https://doi.org/10.1016/s1369-5274(01)00269-7.
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    • Adamo, J. E., J. J. Moskow, A. S. Gladfelter, D. Viterbo, D. J. Lew, and P. J. Brennwald. “Yeast Cdc42 functions at a late step in exocytosis, specifically during polarized growth of the emerging bud.” J Cell Biol 155, no. 4 (November 12, 2001): 581–92. https://doi.org/10.1083/jcb.200106065.
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    • Adamo, J. E., J. J. Moskow, A. S. Gladfelter, D. Viterbo, D. J. Lew, and P. J. Brennwald. “Yeast Cdc42 functions at a late step in exocytosis, specifically during polarized growth of the emerging bud.” Journal of Cell Biology 155, no. 3 (October 29, 2001): 581–92. https://doi.org/10.1083/jcb.200106065.
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    • Gladfelter, A. S., J. J. Moskow, T. R. Zyla, and D. J. Lew. “Isolation and characterization of effector-loop mutants of CDC42 in yeast.” Mol Biol Cell 12, no. 5 (May 2001): 1239–55. https://doi.org/10.1091/mbc.12.5.1239.
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    • Moskow, J. J., A. S. Gladfelter, R. E. Lamson, P. M. Pryciak, and D. J. Lew. “Role of Cdc42p in pheromone-stimulated signal transduction in Saccharomyces cerevisiae.” Mol Cell Biol 20, no. 20 (October 2000): 7559–71. https://doi.org/10.1128/MCB.20.20.7559-7571.2000.
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  • Book Sections

    • Langdon, Erin M., and Amy S. Gladfelter. “Probing RNA Structure in Liquid-Liquid Phase Separation Using SHAPE-MaP.,” 611:67–79, 2018. https://doi.org/10.1016/bs.mie.2018.09.039.
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    • Gladfelter, A. S., and P. Sudbery. “Septins in Four Model Fungal Systems: Diversity in Form and Function.” In The Septins, 125–46, 2008. https://doi.org/10.1002/9780470779705.ch5.
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  • Conference Papers

    • Gladfelter, Amy S., and Cristina Montagna. “Seeking truth on Monte Verita. Workshop on the molecular biology and biochemistry of septins and septin function.” In Embo Rep, 8:1120–26, 2007. https://doi.org/10.1038/sj.embor.7401116.
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    • Martyanov, V., L. Elderon, A. Gladfelter, D. R. Nair, and R. H. Gross. “Identifying fungal regulatory motif patterns using SCOPE, an ensemble learning method motif finder.” In Proceedings of the 7th Ieee International Conference on Bioinformatics and Bioengineering, Bibe, 1183–87, 2007. https://doi.org/10.1109/BIBE.2007.4375712.
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