Scholars@Duke
Arnaldo Carreira Rosario

Arnaldo Carreira Rosario

Assistant Professor of Biology
Biology
arnaldo.carreira@duke.edu
137 Bio Science, Box 90338, Durham, NC 27708
137 Bio Science, Box 90338, Durham, NC 27708

Selected Publications

Mechanosensory input during circuit formation shapes Drosophila motor behavior through patterned spontaneous network activity.

Journal Article Current biology : CB · December 2021 Neural activity sculpts circuit wiring in many animals. In vertebrates, patterned spontaneous network activity (PaSNA) generates sensory maps and establishes local circuits.1-3 However, it remains unclear how PaSNA might shape neuronal circuits ... Full text Cite

MDN brain descending neurons coordinately activate backward and inhibit forward locomotion.

Journal Article eLife · August 2018 Command-like descending neurons can induce many behaviors, such as backward locomotion, escape, feeding, courtship, egg-laying, or grooming (we define 'command-like neuron' as a neuron whose activation elicits or 'commands' a specific behavior). In most an ... Full text Cite

Neural circuits driving larval locomotion in Drosophila.

Journal Article Neural development · April 2018 More than 30 years of studies into Drosophila melanogaster neurogenesis have revealed fundamental insights into our understanding of axon guidance mechanisms, neural differentiation, and early cell fate decisions. What is less understood is how a group of ... Full text Cite

Repression of Pumilio Protein Expression by Rbfox1 Promotes Germ Cell Differentiation.

Journal Article Developmental cell · March 2016 RNA-binding Fox (Rbfox) proteins have well-established roles in regulating alternative splicing, but specific Rbfox isoforms lack nuclear localization signals and accumulate in the cytoplasm. The potential splicing-independent functions of these proteins r ... Full text Cite

A competitive cell fate switch.

Other Developmental cell · November 2014 Whereas tissue development and homeostasis depend on stem cell self-renewal and differentiation, the mechanisms that balance these processes remain incompletely understood. Pan et al. (2014) now show that competitive protein-protein interactions between Ba ... Full text Cite

Sepsis-induced potentiation of peritoneal macrophage migration is mitigated by programmed cell death receptor-1 gene deficiency.

Journal Article Journal of innate immunity · January 2014 The effect of programmed cell death receptor-1 (PD-1) on phagocyte function has not been extensively described. Here we report that experimental mouse sepsis, cecal ligation and puncture (CLP), induced a marked increase in peritoneal macrophage random migr ... Full text Cite

Recombineering homologous recombination constructs in Drosophila.

Journal Article Journal of visualized experiments : JoVE · July 2013 The continued development of techniques for fast, large-scale manipulation of endogenous gene loci will broaden the use of Drosophila melanogaster as a genetic model organism for human-disease related research. Recent years have seen technical advancements ... Full text Cite

Mei-p26 cooperates with Bam, Bgcn and Sxl to promote early germline development in the Drosophila ovary.

Journal Article PloS one · January 2013 In the Drosophila female germline, spatially and temporally specific translation of mRNAs governs both stem cell maintenance and the differentiation of their progeny. However, the mechanisms that control and coordinate different modes of translational repr ... Full text Cite