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Xuhui Bao

Adjunct Professor in the Department of Pathology
Pathology
Duke Box 3712, Durham, NC 27710
Duke Box 3712, Durham, NC 27710

Research Interests


My current research focuses on below two dimensions of cancer research, especially in the field of cancer immunological research: (1)The clinic-based discovery of novel antitumor targets and their relationships to those key carcinogenesis-related pathways and tumor immune microenvironment, using state-of-the-art omics data mining tools, CRISPR-Cas9 related gene editing technologies, and high-throughput screening methods; (2)The clinic-oriented development of novel antitumor strategies based on the above discoveries, to be initially validated at the preclinical level both in vitro and in vivo, and ultimately translated into clinical trials in the late stage.

Selected Grants


Targeting apoptotic caspases to enhance cancer radiotherapy

ResearchResearch Associate · Awarded by National Institutes of Health · 2017 - 2023

Necroptotic genes in cancer cellular response to radiation

ResearchResearch Associate · Awarded by National Institutes of Health · 2017 - 2023

A Genetically Modified Poliovirus and Immunotoxin for Malignant Brain Tumors

ResearchResearch Assistant · Awarded by Brain Tumor Research Charity · 2013 - 2017

Immunosequencing of poliovirus and immunotoxin treated brain tumor samples

ResearchResearch Assistant · Awarded by Uncle Kory Foundation · 2015 - 2016