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Bharathi Upadhya

Associate Professor of Medicine
Medicine, Cardiology

Current Appointments & Affiliations


Associate Professor of Medicine · 2023 - Present Medicine, Cardiology, Medicine

Recent Publications


Effects of Blood Pressure Control on Arterial Stiffness Mechanisms in SPRINT: A Randomized Controlled Trial.

Journal Article Hypertension · June 2025 BACKGROUND: The longitudinal impact of blood pressure (BP) control on the components of arterial stiffness has not been studied. METHODS: The SPRINT (Systolic BP Intervention Trial) compared an intensive systolic BP goal (<120 mm Hg) to a standard goal (<1 ... Full text Link to item Cite

The role of echocardiography in the diagnosis of heart failure with preserved ejection fraction.

Journal Article Heart Fail Rev · May 12, 2025 Heart failure (HF) with preserved ejection fraction (HFpEF) is the most common form of HF in older adults. While manifest as distinct clinical phenotypes, almost all patients with HFpEF will present with exercise intolerance or exertional dyspnea. Distingu ... Full text Link to item Cite

Long-term Changes in Body Composition and Exercise Capacity Following Calorie Restriction and Exercise Training in Older Patients with Obesity and Heart Failure With Preserved Ejection Fraction.

Journal Article J Card Fail · March 2025 BACKGROUND: Obesity combined with heart failure with preserved ejection fraction (HFpEF) is the dominant form of HF among older persons. In a randomized trial, we previously showed that a 5-month calorie restriction (CR) program, with or without aerobic ex ... Full text Link to item Cite
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Recent Grants


Repurposing 99mTc-tilmanocept Imaging for Cardiac Sarcoidosis

ResearchCo Investigator · Awarded by The Foundation for Sarcoidosis Research · 2024 - 2026

Physical Rehabilitation for Older Patients with Acute HFpEF-The REHAB-HFpEF Trial - Site Administration

Clinical TrialCollaborating Investigator · Awarded by Wake Forest University Health Sciences · 2023 - 2026

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Education, Training & Certifications


University of Mysore (India) · 1995 M.B.B.S.