Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Vascular Neurology Fellowship, Dept. Of Neurology, Yale New Haven Hospital, Yale University School of Medicine 2016 - 2017
  • Neurology Residency, Dept. Of Neurology, Yale New Haven Hospital, Yale University School of Medicine 2013 - 2016
  • Internal Medicine Internship, Dept. Of Internal Medicine, Yale New Haven Hospital, Yale University School of Medicine 2012 - 2013
  • Internal Medicine Internship, Internal Medicine And General Surgery, St. Vincent's University Hospital 2011 - 2012
  • M.B.B.Ch., University College Dublin (Ireland) 2001
• Recognition
• 

  Awards & Honors

  • Fellowship of the American Heart Association (FAHA). American Heart Association. 2021
• Expertise
• 

  Subject Headings

  • Cerebrovascular disease
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Mac Grory, Brian, Matthew Schrag, Sven Poli, Chantal J. Boisvert, Martin S. Spitzer, Maximillian Schultheiss, Max Nedelmann, et al. “Structural and Functional Imaging of the Retina in Central Retinal Artery Occlusion - Current Approaches and Future Directions.” J Stroke Cerebrovasc Dis 30, no. 7 (July 2021): 105828. https://doi.org/10.1016/j.jstrokecerebrovasdis.2021.105828.
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    • Mac Grory, Brian, Sean R. Landman, Paul D. Ziegler, Chantal J. Boisvert, Shane P. Flood, Christoph Stretz, Tracy E. Madsen, et al. “Detection of Atrial Fibrillation After Central Retinal Artery Occlusion.” Stroke, June 7, 2021, STROKEAHA120033934. https://doi.org/10.1161/STROKEAHA.120.033934.
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    • Esparza, Rogelio, Julia R. Schneider, Brian Mac Grory, and Erez Nossek. “How I do it: endarterectomy for carotid web.” Acta Neurochir (Wien) 163, no. 6 (June 2021): 1763–66. https://doi.org/10.1007/s00701-021-04841-z.
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    • Mac Grory, Brian, Ian J. Saldanha, Eva A. Mistry, Christoph Stretz, Sven Poli, Marek Sykora, Lars Kellert, et al. “Thrombolytic therapy for wake-up stroke: A systematic review and meta-analysis.” Eur J Neurol 28, no. 6 (June 2021): 2006–16. https://doi.org/10.1111/ene.14839.
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    • Mac Grory, Brian, Matthew Schrag, Valérie Biousse, Karen L. Furie, Marie Gerhard-Herman, Patrick J. Lavin, Lucia Sobrin, et al. “Management of Central Retinal Artery Occlusion: A Scientific Statement From the American Heart Association.” Stroke 52, no. 6 (June 2021): e282–94. https://doi.org/10.1161/STR.0000000000000366.
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    • Romano, Jose G., Hannah Gardener, Iszet Campo-Bustillo, Yosef Khan, Sofie Tai, Nikesha Riley, Eric E. Smith, et al. “Predictors of Outcomes in Patients With Mild Ischemic Stroke Symptoms: MaRISS.” Stroke 52, no. 6 (June 2021): 1995–2004. https://doi.org/10.1161/STROKEAHA.120.032809.
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    • Yaghi, Shadi, Eytan Raz, Dixon Yang, Shawna Cutting, Brian Mac Grory, Mitchell Sv Elkind, and Adam de Havenon. “Lacunar stroke: mechanisms and therapeutic implications.” J Neurol Neurosurg Psychiatry, May 26, 2021. https://doi.org/10.1136/jnnp-2021-326308.
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    • Yaghi, Shadi, Adam de Havenon, Sara Rostanski, Alexandra Kvernland, Brian Mac Grory, Karen L. Furie, Anthony S. Kim, J Donald Easton, S Claiborne Johnston, and Nils Henninger. “Carotid Stenosis and Recurrent Ischemic Stroke: A Post-Hoc Analysis of the POINT Trial.” Stroke, May 4, 2021, STROKEAHA121034089. https://doi.org/10.1161/STROKEAHA.121.034089.
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    • Paciaroni, Maurizio, Giancarlo Agnelli, Michela Giustozzi, Valeria Caso, Elisabetta Toso, Filippo Angelini, Isabella Canavero, et al. “Risk Factors for Intracerebral Hemorrhage in Patients With Atrial Fibrillation on Non-Vitamin K Antagonist Oral Anticoagulants for Stroke Prevention.” Stroke 52, no. 4 (April 2021): 1450–54. https://doi.org/10.1161/STROKEAHA.120.031827.
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    • Schrag, Matthew, Brian Mac Grory, Alex Nackenoff, James Eaton, Eva Mistry, Howard Kirshner, Shadi Yaghi, and Christopher R. Ellis. “Left Atrial Appendage Closure for Patients with Cerebral Amyloid Angiopathy and Atrial Fibrillation: the LAA-CAA Cohort.” Transl Stroke Res 12, no. 2 (April 2021): 259–65. https://doi.org/10.1007/s12975-020-00838-5.
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    • Kim, Taewon, Christine Park, Pratik Y. Chhatbar, Jody Feld, Brian Mac Grory, Chang S. Nam, Pu Wang, Mengyue Chen, Xiaoning Jiang, and Wuwei Feng. “Effect of Low Intensity Transcranial Ultrasound Stimulation on Neuromodulation in Animals and Humans: An Updated Systematic Review.” Front Neurosci 15 (2021): 620863. https://doi.org/10.3389/fnins.2021.620863.
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    • Yaghi, S., N. Henninger, J. A. Giles, C. Leon Guerrero, E. Mistry, A. L. Liberman, D. Asad, et al. “Ischaemic stroke on anticoagulation therapy and early recurrence in acute cardioembolic stroke: The IAC study.” Journal of Neurology, Neurosurgery and Psychiatry, January 1, 2021. https://doi.org/10.1136/jnnp-2021-326166.
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    • Yaghi, Shadi, Seena Dehkharghani, Eytan Raz, Mahesh Jayaraman, Omar Tanweer, Brian Mac Grory, Nils Henninger, Maarten G. Lansberg, Gregory W. Albers, and Adam de Havenon. “The Effect of Hyperglycemia on Infarct Growth after Reperfusion: An Analysis of the DEFUSE 3 trial.” J Stroke Cerebrovasc Dis 30, no. 1 (January 2021): 105380. https://doi.org/10.1016/j.jstrokecerebrovasdis.2020.105380.
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    • Mac Grory, Brian, Bart J. Emmer, Stefan D. Roosendaal, David Zagzag, Shadi Yaghi, and Erez Nossek. “Carotid web: an occult mechanism of embolic stroke.” J Neurol Neurosurg Psychiatry 91, no. 12 (December 2020): 1283–89. https://doi.org/10.1136/jnnp-2020-323938.
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    • Mac Grory, Brian, and Shadi Yaghi. “Response by Mac Grory and Yaghi to Letter Regarding Article, "SARS-CoV-2 and Stroke in a New York Healthcare System".” Stroke 51, no. 12 (December 2020): e373–74. https://doi.org/10.1161/STROKEAHA.120.032519.
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    • Zhou, Eric, Aaron Lord, Amelia Boehme, Nils Henninger, Adam de Havenon, Farhaan Vahidy, Koto Ishida, et al. “Risk of Ischemic Stroke in Patients With Atrial Fibrillation After Extracranial Hemorrhage.” Stroke 51, no. 12 (December 2020): 3592–99. https://doi.org/10.1161/STROKEAHA.120.029959.
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    • Yaghi, Shadi, Tushar Trivedi, Nils Henninger, James Giles, Angela Liu, Muhammad Nagy, Ashutosh Kaushal, et al. “Anticoagulation Timing in Cardioembolic Stroke and Recurrent Event Risk.” Ann Neurol 88, no. 4 (October 2020): 807–16. https://doi.org/10.1002/ana.25844.
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    • Reznik, Michael E., Nasir Fakhri, Scott Moody, Kayleigh Murray, Samantha Costa, Shadi Yaghi, Matthew Schrag, et al. “Arrival blood pressure in hypertensive and non-hypertensive spontaneous intracerebral hemorrhage.” J Neurol Sci 416 (September 15, 2020): 117000. https://doi.org/10.1016/j.jns.2020.117000.
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    • Yaghi, Shadi, Eva Mistry, Ava L. Liberman, James Giles, Syed Daniyal Asad, Angela Liu, Muhammad Nagy, et al. “Anticoagulation Type and Early Recurrence in Cardioembolic Stroke: The IAC Study.” Stroke 51, no. 9 (September 2020): 2724–32. https://doi.org/10.1161/STROKEAHA.120.028867.
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    • Mac Grory, Brian, and Matthew Schrag. “Re: Flaxel et al.: Retinal and ophthalmic artery occlusions Preferred Practice Pattern® (Ophthalmology. 2020;127:P259-P287).” Ophthalmology 127, no. 8 (August 2020): e59–60. https://doi.org/10.1016/j.ophtha.2020.04.022.
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    • Salwi, Sanjana, Shawna Cutting, Alan D. Salgado, Kiersten Espaillat, Matthew R. Fusco, Michael T. Froehler, Rohan V. Chitale, et al. “Mechanical Thrombectomy in Ischemic Stroke Patients with Severe Pre-Stroke Disability.” J Stroke Cerebrovasc Dis 29, no. 8 (August 2020): 104952. https://doi.org/10.1016/j.jstrokecerebrovasdis.2020.104952.
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    • Havenon, Adam de, Pooja Khatri, Shyam Prabhakaran, Sharon D. Yeatts, Cecilia Peterson, Daniel Sacchetti, Matthew Alexander, et al. “Hypoperfusion Distal to Anterior Circulation Intracranial Atherosclerosis is Associated with Recurrent Stroke.” J Neuroimaging 30, no. 4 (July 2020): 468–70. https://doi.org/10.1111/jon.12710.
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    • Mac Grory, Brian, Alex Nackenoff, Sven Poli, Martin S. Spitzer, Max Nedelmann, Benoit Guillon, Cécile Preterre, et al. “Intravenous Fibrinolysis for Central Retinal Artery Occlusion: A Cohort Study and Updated Patient-Level Meta-Analysis.” Stroke 51, no. 7 (July 2020): 2018–25. https://doi.org/10.1161/STROKEAHA.119.028743.
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    • Yaghi, Shadi, Koto Ishida, Jose Torres, Brian Mac Grory, Eytan Raz, Kelley Humbert, Nils Henninger, et al. “SARS-CoV-2 and Stroke in a New York Healthcare System.” Stroke 51, no. 7 (July 2020): 2002–11. https://doi.org/10.1161/STROKEAHA.120.030335.
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    • Yaghi, Shadi, Nils Henninger, Erica Scher, James Giles, Angela Liu, Muhammad Nagy, Ashutosh Kaushal, et al. “Early ischaemic and haemorrhagic complications after atrial fibrillation-related ischaemic stroke: analysis of the IAC study.” J Neurol Neurosurg Psychiatry 91, no. 7 (July 2020): 750–55. https://doi.org/10.1136/jnnp-2020-323041.
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    • Mahta, Ali, Shadi Yaghi, Michael E. Reznik, Bradford B. Thompson, Linda C. Wendell, Shyam Rao, Nicholas S. Potter, et al. “Serum alpha-1 antitrypsin in acute ischemic stroke: A prospective pilot study.” J Clin Neurosci 76 (June 2020): 20–24. https://doi.org/10.1016/j.jocn.2020.04.074.
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    • Peng, Teng J., Christoph Stretz, Razaz Mageid, Brian Mac Grory, Shadi Yaghi, Charles Matouk, and Joseph Schindler. “Carotid-Cavernous Fistula Presenting With Bilateral Abducens Palsy.” Stroke 51, no. 6 (June 2020): e107–10. https://doi.org/10.1161/STROKEAHA.120.029306.
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    • Mac Grory, Brian, Patrick Lavin, Howard Kirshner, and Matthew Schrag. “Response by Mac Grory et al to Letter Regarding Article, "Thrombolytic Therapy for Acute Central Retinal Artery Occlusion".” Stroke 51, no. 5 (May 2020): e96. https://doi.org/10.1161/STROKEAHA.120.029609.
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    • Agarwal, Shashank, Erica Scher, Aaron Lord, Jennifer Frontera, Koto Ishida, Jose Torres, Sara Rostanski, et al. “Redefined Measure of Early Neurological Improvement Shows Treatment Benefit of Alteplase Over Placebo.” Stroke 51, no. 4 (April 2020): 1226–30. https://doi.org/10.1161/STROKEAHA.119.027476.
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    • Chang, Andrew D., Gian C. Ignacio, Ronald Akiki, Brian Mac Grory, Shawna S. Cutting, Tina Burton, Mahesh Jayaraman, et al. “Increased Left Atrial Appendage Density on Computerized Tomography is Associated with Cardioembolic Stroke.” J Stroke Cerebrovasc Dis 29, no. 4 (April 2020): 104604. https://doi.org/10.1016/j.jstrokecerebrovasdis.2019.104604.
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    • Yaghi, Shadi, Pooja Khatri, Adam de Havenon, Sharon Yeatts, Andrew D. Chang, Shawna Cutting, Brian Mac Grory, et al. “Peri-procedural stroke or death in stenting of symptomatic severe intracranial stenosis.” J Neurointerv Surg 12, no. 4 (April 2020): 374–79. https://doi.org/10.1136/neurintsurg-2019-015225.
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    • Agarwal, Shashank, Shawna Cutting, Brian Mac Grory, Tina Burton, Mahesh Jayaraman, Ryan McTaggart, Michael Reznik, et al. “Redefining Early Neurological Improvement After Reperfusion Therapy in Stroke.” J Stroke Cerebrovasc Dis 29, no. 2 (February 2020): 104526. https://doi.org/10.1016/j.jstrokecerebrovasdis.2019.104526.
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    • Mac Grory, Brian, Patrick Lavin, Howard Kirshner, and Matthew Schrag. “Thrombolytic Therapy for Acute Central Retinal Artery Occlusion.” Stroke 51, no. 2 (February 2020): 687–95. https://doi.org/10.1161/STROKEAHA.119.027478.
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    • Yaghi, Shadi, Andrew Chang, Gian Ignacio, Erica Scher, Nikhil Panda, Antony Chu, Michael Wu, et al. “Left Atrial Appendage Morphology Improves Prediction of Stagnant Flow and Stroke Risk in Atrial Fibrillation.” Circ Arrhythm Electrophysiol 13, no. 2 (February 2020): e008074. https://doi.org/10.1161/CIRCEP.119.008074.
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    • Brown, Stacy C., Guido J. Falcone, Ryan M. Hebert, Shadi Yaghi, Brian Mac Grory, and Christoph Stretz. “Stenting for Acute Carotid Artery Dissection.” Stroke 51, no. 1 (January 2020): e3–6. https://doi.org/10.1161/STROKEAHA.119.027827.
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    • Montalvo, Mayra, Eva Mistry, Andrew Davey Chang, Aleksandra Yakhkind, Katarina Dakay, Idrees Azher, Ashutosh Kaushal, et al. “Predicting symptomatic intracranial haemorrhage after mechanical thrombectomy: the TAG score.” J Neurol Neurosurg Psychiatry 90, no. 12 (December 2019): 1370–74. https://doi.org/10.1136/jnnp-2019-321184.
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    • Mac Grory, B., S. P. Flood, E. Apostolidou, and S. Yaghi. “Cryptogenic Stroke: Diagnostic Workup and Management.” Current Treatment Options in Cardiovascular Medicine 21, no. 11 (November 1, 2019). https://doi.org/10.1007/s11936-019-0786-4.
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    • Smith, Jonathan H., Brian Mac Grory, Richard J. Butterfield, Babar Khokhar, Bryce L. Falk, and Lisa A. Marks. “CSF Pressure, Volume, and Post-Dural Puncture Headache: A Case-Control Study and Systematic Review.” Headache 59, no. 8 (September 2019): 1324–38. https://doi.org/10.1111/head.13602.
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    • Yaghi, Shadi, Brian Mac Grory, Shyam Prabhakaran, Sharon D. Yeatts, Shawna Cutting, Mahesh Jayaraman, Daniel Sacchetti, et al. “Infarct Pattern, Perfusion Mismatch Thresholds, and Recurrent Cerebrovascular Events in Symptomatic Intracranial Stenosis.” J Neuroimaging 29, no. 5 (September 2019): 640–44. https://doi.org/10.1111/jon.12630.
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    • Mac Grory, Brian, Shane Flood, Matthew Schrag, Maurizio Paciaroni, and Shadi Yaghi. “Anticoagulation Resumption After Stroke from Atrial Fibrillation.” Curr Atheroscler Rep 21, no. 8 (May 20, 2019): 29. https://doi.org/10.1007/s11883-019-0790-x.
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    • Azher, Idrees, Ashutosh Kaushal, Andrew Chang, Shawna Cutting, Brian Mac Grory, Tina Burton, Katarina Dakay, et al. “Serum Troponin Level in Acute Ischemic Stroke Identifies Patients with Visceral Infarcts.” J Stroke Cerebrovasc Dis 28, no. 5 (May 2019): 1173–77. https://doi.org/10.1016/j.jstrokecerebrovasdis.2019.01.004.
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    • Jayaraman, Mahesh V., Thomas Kishkovich, Grayson L. Baird, Morgan L. Hemendinger, Eric L. Tung, Shadi Yaghi, Shawna Cutting, et al. “Association between age and outcomes following thrombectomy for anterior circulation emergent large vessel occlusion is determined by degree of recanalisation.” J Neurointerv Surg 11, no. 2 (February 2019): 114–18. https://doi.org/10.1136/neurintsurg-2018-013964.
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    • Mac Grory, Brian, Derrick Cheng, Curt Doberstein, Mahesh V. Jayaraman, and Shadi Yaghi. “Ischemic Stroke and Internal Carotid Artery Web.” Stroke 50, no. 2 (February 2019): e31–34. https://doi.org/10.1161/STROKEAHA.118.024014.
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    • Reznik, Michael E., Shadi Yaghi, Mahesh V. Jayaraman, Ryan A. McTaggart, Morgan Hemendinger, Brian C. Mac Grory, Tina M. Burton, et al. “Baseline NIH Stroke Scale is an inferior predictor of functional outcome in the era of acute stroke intervention.” Int J Stroke 13, no. 8 (October 2018): 806–10. https://doi.org/10.1177/1747493018783759.
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    • Mac Grory, Brian, Andrew Chang, Michael K. Atalay, and Shadi Yaghi. “Left Atrial Appendage Thrombus and Embolic Stroke.” Stroke 49, no. 9 (September 2018): e286–89. https://doi.org/10.1161/STROKEAHA.118.022674.
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    • James, Brandon, Andrew D. Chang, Ryan A. McTaggart, Morgan Hemendinger, Brian Mac Grory, Shawna M. Cutting, Tina M. Burton, et al. “Predictors of symptomatic intracranial haemorrhage in patients with an ischaemic stroke with neurological deterioration after intravenous thrombolysis.” J Neurol Neurosurg Psychiatry 89, no. 8 (August 2018): 866–69. https://doi.org/10.1136/jnnp-2017-317341.
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    • Sacchetti, Daniel C., Shawna M. Cutting, Ryan A. McTaggart, Andrew D. Chang, Morgan Hemendinger, Brian Mac Grory, Matthew S. Siket, et al. “Perfusion imaging and recurrent cerebrovascular events in intracranial atherosclerotic disease or carotid occlusion.” Int J Stroke 13, no. 6 (August 2018): 592–99. https://doi.org/10.1177/1747493018764075.
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    • Reznik, Michael E., Shadi Yaghi, Mahesh V. Jayaraman, Ryan A. McTaggart, Morgan Hemendinger, Brian C. Mac Grory, Tina M. Burton, et al. “Level of consciousness at discharge and associations with outcome after ischemic stroke.” J Neurol Sci 390 (July 15, 2018): 102–7. https://doi.org/10.1016/j.jns.2018.04.022.
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    • Ricci, Brittany, Andrew D. Chang, Morgan Hemendinger, Katarina Dakay, Shawna Cutting, Tina Burton, Brian Mac Grory, et al. “A Simple Score That Predicts Paroxysmal Atrial Fibrillation on Outpatient Cardiac Monitoring after Embolic Stroke of Unknown Source.” J Stroke Cerebrovasc Dis 27, no. 6 (June 2018): 1692–96. https://doi.org/10.1016/j.jstrokecerebrovasdis.2018.01.028.
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    • Yaghi, Shadi, Andrew D. Chang, Peter Hung, Brian Mac Grory, Scott Collins, Ajay Gupta, Jacques Reynolds, et al. “Left Atrial Appendage Morphology and Embolic Stroke of Undetermined Source: A Cross-Sectional Multicenter Pilot Study.” J Stroke Cerebrovasc Dis 27, no. 6 (June 2018): 1497–1501. https://doi.org/10.1016/j.jstrokecerebrovasdis.2017.12.036.
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    • Mac Grory, Brian, Linh Vu, Shawna Cutting, Evadne Marcolini, Christopher Gottschalk, and David Greer. “Distinguishing Characteristics of Headache in Nontraumatic Subarachnoid Hemorrhage.” Headache 58, no. 3 (March 2018): 364–70. https://doi.org/10.1111/head.13218.
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    • Yaghi, Shadi, Andrew D. Chang, Brittany A. Ricci, Mahesh V. Jayaraman, Ryan A. McTaggart, Morgan Hemendinger, Priya Narwal, et al. “Early Elevated Troponin Levels After Ischemic Stroke Suggests a Cardioembolic Source.” Stroke 49, no. 1 (January 2018): 121–26. https://doi.org/10.1161/STROKEAHA.117.019395.
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    • Taylor, Roslyn A., Che-Feng Chang, Brittany A. Goods, Matthew D. Hammond, Brian Mac Grory, Youxi Ai, Arthur F. Steinschneider, et al. “TGF-β1 modulates microglial phenotype and promotes recovery after intracerebral hemorrhage.” J Clin Invest 127, no. 1 (January 3, 2017): 280–92. https://doi.org/10.1172/JCI88647.
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    • Malhotra, Ajay, Joseph Schindler, Brian Mac Grory, Stacy Y. Chu, Teddy S. Youn, Charles Matouk, David M. Greer, and Matthew Schrag. “Cerebral Microhemorrhages and Meningeal Siderosis in Infective Endocarditis.” Cerebrovasc Dis 43, no. 1–2 (2017): 59–67. https://doi.org/10.1159/000452718.
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    • Mac Grory, Brian, Edward T. O’Connor, Ken D. O’Halloran, and James F. X. Jones. “The effect of pro-inflammatory cytokines on the discharge rate of vagal nerve paraganglia in the rat.” Respir Physiol Neurobiol 171, no. 2 (April 30, 2010): 122–27. https://doi.org/10.1016/j.resp.2010.03.001.
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  • Book Sections

    • Mac Grory, B., L. J. Hirsch, E. Gilmore, and K. N. Sheth. “Management of Postoperative Seizures.” In Neurocritical Care Management of the Neurosurgical Patient, 497–507, 2018. https://doi.org/10.1016/B978-0-323-32106-8.00049-2.
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    • Mac Grory, Brian. “High-Dose Atorvastatin after Stroke or Transient Ischemic Attack.” In 50 Studies Every Neurologist Should Know, 311–16. Oxford University Press, 2016. https://doi.org/10.1093/med/9780199377527.003.0046.
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    • Mac Grory, Brian. “Riluzole for Amyotrophic Lateral Sclerosis.” In 50 Studies Every Neurologist Should Know, 163–68. Oxford University Press, 2016. https://doi.org/10.1093/med/9780199377527.003.0024.
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