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Chanjuan Shi

Professor of Pathology
Pathology
40 Duke Medicine Circle, Box 3712 DUMC, Durham, NC 27710
40 Duke Medicine Circle, Box 3712 DUMC, Durham, NC 27710

Overview


Dr. Shi is a gastrointestinal (GI)/liver pathologist. Her particular areas of interest are GI and pancreatic neuroendocrine tumors and pancreatic pathology. Her research interests include 1)  Pathobiology of GI and pancreatic neuroendocrine tumors and 2) Identification of diagnostic, prognostic and therapeutic biomarkers for colorectal and pancreatic cancers

Current Duke Appointments & Affiliations


Professor of Pathology · 2021 - Present Pathology, Clinical Science Departments
Member of the Duke Cancer Institute · 2020 - Present Duke Cancer Institute, Institutes and Centers

Recent Scholarly Works


Changes in the 6th edition of the World Health Organization classification of tumours of the digestive system.

Journal article Histopathology · June 2026 The 6th Edition of the WHO Classification of Digestive System Tumours represents a significant update to the 5th edition. It integrates pathological, new molecular, and clinical insights to refine the taxonomy of digestive system neoplasms. The revised cla ... Full text Link to item Cite

Serotonin Expression and β-Cell Phenotype Are Associated With Indolent Behavior in Pancreatic Neuroendocrine Tumors With Sclerosing Morphology.

Journal article J Surg Oncol · June 2026 BACKGROUND AND OBJECTIVES: ARX and PDX1 transcription factors have been considered indicators of the cell of origin for pancreatic neuroendocrine tumors (PanNETs). Some PanNETs show dense fibrosis (sclerosing morphology) and an association with serotonin e ... Full text Link to item Cite
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Recent Grants


Biomarker validation for intraductal papillary mucinous neoplasms of the pancreas

ResearchInvestigator · Awarded by National Cancer Institute · 2018 - 2028

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Education


Dalhousie University (Canada) · 2002 Ph.D.
Zhejiang University (China) · 1989 M.D.