Chanjuan Shi | Scholars@Duke

Chanjuan Shi
Professor of Pathology

Dr. Shi is a gastrointestinal (GI)/liver pathologist. Her particular areas of interest are GI and pancreatic neuroendocrine tumors and pancreatic pathology. Her research interests include 1) Pathobiology of GI and pancreatic neuroendocrine tumors and 2) Identification of diagnostic, prognostic and therapeutic biomarkers for colorectal and pancreatic cancers

Current Appointments & Affiliations

Professor of Pathology, Pathology, Clinical Science Departments 2021
Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 2020

Contact Information

40 Duke Medicine Circle, Box 3712 DUMC, Durham, NC 27710
40 Duke Medicine Circle, Box 3712 DUMC, Durham, NC 27710
chanjuan.shi@duke.edu (919) 684-8815

Background
Education, Training, & Certifications
- Ph.D., Dalhousie University (Canada) 2002
- M.D., Zhejiang University (China) 1989
Medical Licensure
- 2019-02404. North Carolina. 2019
Previous Appointments & Affiliations
- Professor of Pathology, Pathology, Clinical Science Departments 2020
Research
External Relationships
- Q2 Solutions
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Shi, Chanjuan, Brian D. Badgwell, Heike I. Grabsch, Michael K. Gibson, Seung-Mo Hong, Priyanthi Kumarasinghe, Alfred K. Lam, et al. “Data Set for Reporting Carcinoma of the Stomach in Gastrectomy.” Archives of Pathology & Laboratory Medicine, December 17, 2021. https://doi.org/10.5858/arpa.2021-0225-oa.
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  - Shi, Chanjuan, Rachel Jug, Sarah M. Bean, William R. Jeck, and Cynthia D. Guy. “Primary hepatic neoplasms arising in cirrhotic livers can have a variable spectrum of neuroendocrine differentiation.” Hum Pathol 116 (October 2021): 63–72. https://doi.org/10.1016/j.humpath.2021.07.007.
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  - Stewart, Melissa K., Sandra L. Kavalukas, Christopher M. Bonfield, Kristen K. Ciombor, Chanjuan Shi, Lisa A. Kachnic, and Alexander T. Hawkins. “Rectothecal Fistula Secondary to a Tailgut Cyst With Malignant Transformation: An Abnormal Connection and Unusual Pathology.” The American Surgeon 87, no. 7 (July 2021): 1126–28. https://doi.org/10.1177/0003134820940733.
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  - Short, Sarah P., Jennifer M. Pilat, Caitlyn W. Barrett, Vishruth K. Reddy, Yael Haberman, Jared R. Hendren, Benjamin J. Marsh, et al. “Colonic Epithelial-Derived Selenoprotein P Is the Source for Antioxidant-Mediated Protection in Colitis-Associated Cancer.” Gastroenterology 160, no. 5 (April 2021): 1694-1708.e3. https://doi.org/10.1053/j.gastro.2020.12.059.
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  - Liang, Jiancong, Chanjuan Shi, William D. Dupont, Safia N. Salaria, Won Jae Huh, Hernan Correa, Joseph T. Roland, Roman E. Perri, and Mary Kay Washington. “Key histopathologic features in idiopathic noncirrhotic portal hypertension: an interobserver agreement study and proposal for diagnostic criteria.” Mod Pathol 34, no. 3 (March 2021): 592–602. https://doi.org/10.1038/s41379-020-00676-8.
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  - Patrinely, J Randall, Ben McGuigan, Sunandana Chandra, Sarah E. Fenton, Akansha Chowdhary, Lucy B. Kennedy, Meghan J. Mooradian, et al. “A multicenter characterization of hepatitis associated with immune checkpoint inhibitors.” Oncoimmunology 10, no. 1 (February 8, 2021): 1875639. https://doi.org/10.1080/2162402X.2021.1875639.
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  - Janssen, Boris V., Faik Tutucu, Stijn van Roessel, Volkan Adsay, Olca Basturk, Fiona Campbell, Claudio Doglioni, et al. “Amsterdam International Consensus Meeting: tumor response scoring in the pathology assessment of resected pancreatic cancer after neoadjuvant therapy.” Mod Pathol 34, no. 1 (January 2021): 4–12. https://doi.org/10.1038/s41379-020-00683-9.
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  - Trinh, Vincent Q-H, Chanjuan Shi, and Changqing Ma. “Gastric neuroendocrine tumours from long-term proton pump inhibitor users are indolent tumours with good prognosis.” Histopathology 77, no. 6 (December 2020): 865–76. https://doi.org/10.1111/his.14220.
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  - Cohen, Allison S., Jun Li, Matthew R. Hight, Eliot McKinley, Allie Fu, Adria Payne, Yang Liu, et al. “TSPO-targeted PET and Optical Probes for the Detection and Localization of Premalignant and Malignant Pancreatic Lesions.” Clin Cancer Res 26, no. 22 (November 15, 2020): 5914–25. https://doi.org/10.1158/1078-0432.CCR-20-1214.
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  - Dashti, Nooshin K., and Chanjuan Shi. “Diagnoses and Difficulties in Mesenteric Pathology.” Surg Pathol Clin 13, no. 3 (September 2020): 521–56. https://doi.org/10.1016/j.path.2020.06.001.
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  - Yohannes, Nathaniel, Jaclyn C. Watkins, Amy G. Weeks, Sarah S. Osmundson, Chanjuan Shi, and Alexandra E. Kovach. “Low-grade Appendiceal Mucinous Neoplasm and Endometriosis: Incidental Coincident Pathologies at Cesarean Section.” Int J Gynecol Pathol 39, no. 5 (September 2020): 498–502. https://doi.org/10.1097/PGP.0000000000000630.
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  - Hoskoppal, Deepthi, Jonathan I. Epstein, Allen M. Gown, Shanna A. Arnold Egloff, Jennifer B. Gordetsky, Chanjuan J. Shi, and Giovanna A. Giannico. “SATB2 protein expression by immunohistochemistry is a sensitive and specific marker of appendiceal and rectosigmoid well differentiated neuroendocrine tumours.” Histopathology 76, no. 4 (March 2020): 550–59. https://doi.org/10.1111/his.14012.
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  - Nordness, Mina F., Stephanie Hamel, Caroline M. Godfrey, Chanjuan Shi, Douglas B. Johnson, Laura W. Goff, Heather O’Dell, Roman E. Perri, and Sophoclis P. Alexopoulos. “Fatal hepatic necrosis after nivolumab as a bridge to liver transplant for HCC: Are checkpoint inhibitors safe for the pretransplant patient?” Am J Transplant 20, no. 3 (March 2020): 879–83. https://doi.org/10.1111/ajt.15617.
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  - Flys, Tamara, Dwight V. Nissley, Cassidy W. Claasen, Dana Jones, Chanjuan Shi, Laura A. Guay, Philippa Musoke, et al. “Erratum to: Sensitive Drug-Resistance Assays Reveal Long-Term Persistence of HIV-1 Variants with the K103N Nevirapine (NVP) Resistance Mutation in Some Women and Infants after the Administration of Single-Dose NVP: HIVNET 012.” The Journal of Infectious Diseases 221, no. 5 (February 2020): 855. https://doi.org/10.1093/infdis/jiz524.
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  - Das, Satya, Chanjuan Shi, Liping Du, Kamran Idrees, and Jordan Berlin. “Adenocarcinoma Ex-Goblet Cell: a Retrospective Experience.” J Gastrointest Cancer 50, no. 4 (December 2019): 709–15. https://doi.org/10.1007/s12029-018-0131-2.
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  - Delbeke, Dominique, Grace Newman, Steve Deppen, Chirayu Shah, Josephine Ndolo, Chanjuan Shi, Christina E. Bailey, Aaron C. Jessop, and Martin P. Sandler. “68Ga-DOTATATE: Significance of Uptake in the Tail of the Pancreas in Patients Without Lesions.” Clin Nucl Med 44, no. 11 (November 2019): 851–54. https://doi.org/10.1097/RLU.0000000000002757.
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  - Gowrikumar, Saiprasad, Rizwan Ahmad, Srijayaprakash Babu Uppada, Mary K. Washington, Chanjuan Shi, Amar B. Singh, and Punita Dhawan. “Correction: Upregulated claudin-1 expression promotes colitis-associated cancer by promoting β-catenin phosphorylation and activation in Notch/p-AKT-dependent manner.” Oncogene 38, no. 38 (September 2019): 6566. https://doi.org/10.1038/s41388-019-0864-9.
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  - Johnson, Douglas B., Wyatt J. McDonnell, Paula I. Gonzalez-Ericsson, Rami N. Al-Rohil, Bret C. Mobley, Joe-Elie Salem, Daniel Y. Wang, et al. “A case report of clonal EBV-like memory CD4+ T cell activation in fatal checkpoint inhibitor-induced encephalitis.” Nat Med 25, no. 8 (August 2019): 1243–50. https://doi.org/10.1038/s41591-019-0523-2.
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  - Roberts, Jordan, Safia N. Salaria, Justin Cates, Yang Wang, Cindy Vnencak-Jones, Jordan Berlin, and Chanjuan Shi. “PD-L1 Expression Patterns in Microsatellite Instability-High Intestinal Adenocarcinoma Subtypes.” Am J Clin Pathol 152, no. 3 (August 1, 2019): 384–91. https://doi.org/10.1093/ajcp/aqz052.
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  - Gowrikumar, Saiprasad, Rizwan Ahmad, Srijayaprakash Babu Uppada, Mary K. Washington, Chanjuan Shi, Amar B. Singh, and Punita Dhawan. “Upregulated claudin-1 expression promotes colitis-associated cancer by promoting β-catenin phosphorylation and activation in Notch/p-AKT-dependent manner.” Oncogene 38, no. 26 (June 2019): 5321–37. https://doi.org/10.1038/s41388-019-0795-5.
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  - Wright, Martha Frances, Justin Cates, Raul S. Gonzalez, Satya Das, Jordan D. Berlin, and Chanjuan Shi. “Impact of Peritoneal Metastasis on Survival of Patients With Small Intestinal Neuroendocrine Tumor.” Am J Surg Pathol 43, no. 4 (April 2019): 559–63. https://doi.org/10.1097/PAS.0000000000001225.
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  - Lehman, Jonathan M., Megan D. Hoeksema, Jeremy Staub, Jun Qian, Bradford Harris, J Clay Callison, Jennifer Miao, et al. “Somatostatin receptor 2 signaling promotes growth and tumor survival in small-cell lung cancer.” Int J Cancer 144, no. 5 (March 1, 2019): 1104–14. https://doi.org/10.1002/ijc.31771.
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  - Dosch, Austin R., Xizi Dai, Alexander A. Gaidarski Iii, Chanjuan Shi, Jason A. Castellanos, Michael N. VanSaun, Nipun B. Merchant, and Nagaraj S. Nagathihalli. “Src kinase inhibition restores E-cadherin expression in dasatinib-sensitive pancreatic cancer cells.” Oncotarget 10, no. 10 (February 1, 2019): 1056–69. https://doi.org/10.18632/oncotarget.26621.
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  - Numbere, Numbereye, Aaron R. Huber, Chanjuan Shi, Justin M. M. Cates, and Raul S. Gonzalez. “Should Ki67 immunohistochemistry be performed on all lesions in multifocal small intestinal neuroendocrine tumours?” Histopathology 74, no. 3 (February 2019): 424–29. https://doi.org/10.1111/his.13771.
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  - Das, Satya, Chanjuan Shi, Tatsuki Koyama, Yi Huang, Raul Gonzalez, Kamran Idrees, Christina Edwards Bailey, and Jordan Berlin. “Peritoneal Carcinomatosis in Well-Differentiated Small-Intestinal Neuroendocrine Tumors with Mesenteric Tumor Deposits.” J Med Surg Pathol 4, no. 1 (2019): 1–10.
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  - Shi, Chanjuan, Fong Cheng Pan, Jessica N. Kim, M Kay Washington, Chandrasekhar Padmanabhan, Christian T. Meyer, Janel L. Kopp, et al. “Differential Cell Susceptibilities to KrasG12D in the Setting of Obstructive Chronic Pancreatitis.” Cell Mol Gastroenterol Hepatol 8, no. 4 (2019): 579–94. https://doi.org/10.1016/j.jcmgh.2019.07.001.
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  - Nagathihalli, Nagaraj S., Jason A. Castellanos, Purushottam Lamichhane, Fanuel Messaggio, Chanjuan Shi, Xizi Dai, Priyamvada Rai, Xi Chen, Michael N. VanSaun, and Nipun B. Merchant. “Inverse Correlation of STAT3 and MEK Signaling Mediates Resistance to RAS Pathway Inhibition in Pancreatic Cancer.” Cancer Res 78, no. 21 (November 1, 2018): 6235–46. https://doi.org/10.1158/0008-5472.CAN-18-0634.
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  - Roberts, Jordan, Raul S. Gonzalez, Frank Revetta, and Chanjuan Shi. “Mesenteric tumour deposits arising from small-intestine neuroendocrine tumours are frequently associated with fibrosis and IgG4-expressing plasma cells.” Histopathology 73, no. 5 (November 2018): 795–800. https://doi.org/10.1111/his.13693.
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  - Srinivasan, Supriya, Tulasigeri Totiger, Chanjuan Shi, Jason Castellanos, Purushottam Lamichhane, Austin R. Dosch, Fanuel Messaggio, et al. “Tobacco Carcinogen-Induced Production of GM-CSF Activates CREB to Promote Pancreatic Cancer.” Cancer Res 78, no. 21 (November 1, 2018): 6146–58. https://doi.org/10.1158/0008-5472.CAN-18-0579.
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  - Gonzalez, Raul S., Justin M. M. Cates, and Chanjuan Shi. “Number, not size, of mesenteric tumor deposits affects prognosis of small intestinal well-differentiated neuroendocrine tumors.” Mod Pathol 31, no. 10 (October 2018): 1560–66. https://doi.org/10.1038/s41379-018-0075-x.
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  - Orr, Jordan, Robert Lockwood, Jordan Roberts, Chanjuan Shi, and Patrick Yachimski. “EUS and confocal endomicroscopic diagnosis of pancreatic acinar cell cystadenoma.” Gastrointest Endosc 88, no. 4 (October 2018): 769–70. https://doi.org/10.1016/j.gie.2018.06.003.
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  - Gibson, William E., Raul S. Gonzalez, Justin M. M. Cates, Eric Liu, and Chanjuan Shi. “Hepatic micrometastases are associated with poor prognosis in patients with liver metastases from neuroendocrine tumors of the digestive tract.” Hum Pathol 79 (September 2018): 109–15. https://doi.org/10.1016/j.humpath.2018.05.006.
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  - Singh, Kshipra, Lori A. Coburn, Mohammad Asim, Daniel P. Barry, Margaret M. Allaman, Chanjuan Shi, M Kay Washington, et al. “Ornithine Decarboxylase in Macrophages Exacerbates Colitis and Promotes Colitis-Associated Colon Carcinogenesis by Impairing M1 Immune Responses.” Cancer Res 78, no. 15 (August 1, 2018): 4303–15. https://doi.org/10.1158/0008-5472.CAN-18-0116.
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  - Alvarez, Mariano J., Prem S. Subramaniam, Laura H. Tang, Adina Grunn, Mahalaxmi Aburi, Gabrielle Rieckhof, Elena V. Komissarova, et al. “A precision oncology approach to the pharmacological targeting of mechanistic dependencies in neuroendocrine tumors.” Nat Genet 50, no. 7 (July 2018): 979–89. https://doi.org/10.1038/s41588-018-0138-4.
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  - Wang, Yang, Cindy L. Vnencak-Jones, Justin M. Cates, and Chanjuan Shi. “Deciphering Elevated Microsatellite Alterations at Selected Tetra/Pentanucleotide Repeats, Microsatellite Instability, and Loss of Heterozygosity in Colorectal Cancers.” J Mol Diagn 20, no. 3 (May 2018): 366–72. https://doi.org/10.1016/j.jmoldx.2018.02.001.
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  - Weiss, Vivian L., Colleen Kiernan, Jesse Wright, Nipun B. Merchant, Alice C. Coogan, and Chanjuan Shi. “Fine-Needle Aspiration-Based Grading of Pancreatic Neuroendocrine Neoplasms Using Ki-67: Is Accurate WHO Grading Possible on Cytologic Material?” J Am Soc Cytopathol 7, no. 3 (May 2018): 154–459. https://doi.org/10.1016/j.jasc.2018.02.001.
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  - Idrees, Kamran, Chandrasekhar Padmanabhan, Eric Liu, Yan Guo, Raul S. Gonzalez, Jordan Berlin, Kimberly B. Dahlman, R Daniel Beauchamp, and Chanjuan Shi. “Frequent BRAF mutations suggest a novel oncogenic driver in colonic neuroendocrine carcinoma.” J Surg Oncol 117, no. 2 (February 2018): 284–89. https://doi.org/10.1002/jso.24834.
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  - Means, Anna L., Tanner J. Freeman, Jing Zhu, Luke G. Woodbury, Paula Marincola-Smith, Chao Wu, Anne R. Meyer, et al. “Epithelial Smad4 Deletion Up-Regulates Inflammation and Promotes Inflammation-Associated Cancer.” Cell Mol Gastroenterol Hepatol 6, no. 3 (2018): 257–76. https://doi.org/10.1016/j.jcmgh.2018.05.006.
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  - Roberts, Jordan A., Raul S. Gonzalez, Satya Das, Jordan Berlin, and Chanjuan Shi. “Expression of PD-1 and PD-L1 in poorly differentiated neuroendocrine carcinomas of the digestive system: a potential target for anti-PD-1/PD-L1 therapy.” Hum Pathol 70 (December 2017): 49–54. https://doi.org/10.1016/j.humpath.2017.10.003.
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  - Erdogan, Begum, Mingfang Ao, Lauren M. White, Anna L. Means, Bryson M. Brewer, Lijie Yang, M Kay Washington, et al. “Cancer-associated fibroblasts promote directional cancer cell migration by aligning fibronectin.” J Cell Biol 216, no. 11 (November 6, 2017): 3799–3816. https://doi.org/10.1083/jcb.201704053.
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  - Gonzalez, Raul S., Safia N. Salaria, Caitlin D. Bohannon, Aaron R. Huber, Michael M. Feely, and Chanjuan Shi. “Immune modulator-induced changes in the gastrointestinal tract - reply.” Histopathology 71, no. 3 (September 2017): 496. https://doi.org/10.1111/his.13233.
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  - Pickup, Michael W., Philip Owens, Agnieszka E. Gorska, Anna Chytil, Fei Ye, Chanjuan Shi, Valerie M. Weaver, Raghu Kalluri, Harold L. Moses, and Sergey V. Novitskiy. “Development of Aggressive Pancreatic Ductal Adenocarcinomas Depends on Granulocyte Colony Stimulating Factor Secretion in Carcinoma Cells.” Cancer Immunol Res 5, no. 9 (September 2017): 718–29. https://doi.org/10.1158/2326-6066.CIR-16-0311.
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  - Thota, Ramya, Raul S. Gonzalez, Jordan Berlin, Dana B. Cardin, and Chanjuan Shi. “Could the PD-1 Pathway Be a Potential Target for Treating Small Intestinal Adenocarcinoma?” Am J Clin Pathol 148, no. 3 (September 1, 2017): 208–14. https://doi.org/10.1093/AJCP/AQX070.
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  - Charoenpitakchai, Mongkon, Eric Liu, Zhiguo Zhao, Tatsuki Koyama, Won Jae Huh, Jordan Berlin, Kenneth Hande, Ronald Walker, and Chanjuan Shi. “In liver metastases from small intestinal neuroendocrine tumors, SSTR2A expression is heterogeneous.” Virchows Arch 470, no. 5 (May 2017): 545–52. https://doi.org/10.1007/s00428-017-2093-3.
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  - Irabor, David O., Olayiwola A. Oluwasola, Olufemi J. Ogunbiyi, Olabiyi G. Ogun, Clement A. Okolo, Marilena Melas, Stephen B. Gruber, Chanjuan Shi, and Leon Raskin. “Microsatellite Instability Is Common in Colorectal Cancer in Native Nigerians.” Anticancer Research 37, no. 5 (May 2017): 2649–54. https://doi.org/10.21873/anticanres.11612.
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  - Gonzalez, Raul S., Safia N. Salaria, Caitlin D. Bohannon, Aaron R. Huber, Michael M. Feely, and Chanjuan Shi. “PD-1 inhibitor gastroenterocolitis: case series and appraisal of 'immunomodulatory gastroenterocolitis'.” Histopathology 70, no. 4 (March 2017): 558–67. https://doi.org/10.1111/his.13118.
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  - Fata, Cynthia R., Raul S. Gonzalez, Eric Liu, Justin M. Cates, and Chanjuan Shi. “Mesenteric Tumor Deposits in Midgut Small Intestinal Neuroendocrine Tumors Are a Stronger Indicator Than Lymph Node Metastasis for Liver Metastasis and Poor Prognosis.” Am J Surg Pathol 41, no. 1 (January 2017): 128–33. https://doi.org/10.1097/PAS.0000000000000751.
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  - Gonzalez, Raul S., Won Jae Huh, Justin M. M. Cates, Kay Washington, R Daniel Beauchamp, Robert J. Coffey, and Chanjuan Shi. “Micropapillary colorectal carcinoma: clinical, pathological and molecular properties, including evidence of epithelial-mesenchymal transition.” Histopathology 70, no. 2 (January 2017): 223–31. https://doi.org/10.1111/his.13068.
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  - Walker, Ronald, Stephen Deppen, Gary Smith, Chanjuan Shi, Jonathan Lehman, Jeff Clanton, Brandon Moore, Rena Burns, Eric L. Grogan, and Pierre P. Massion. “68Ga-DOTATATE PET/CT imaging of indeterminate pulmonary nodules and lung cancer.” Plos One 12, no. 2 (2017): e0171301. https://doi.org/10.1371/journal.pone.0171301.
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  - Wang, Yang, Chanjuan Shi, Rosana Eisenberg, and Cindy L. Vnencak-Jones. “Differences in Microsatellite Instability Profiles between Endometrioid and Colorectal Cancers: A Potential Cause for False-Negative Results?” J Mol Diagn 19, no. 1 (January 2017): 57–64. https://doi.org/10.1016/j.jmoldx.2016.07.008.
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  - Salaria, Safia N., and Chanjuan Shi. “Pancreatic Neuroendocrine Tumors.” Surg Pathol Clin 9, no. 4 (December 2016): 595–617. https://doi.org/10.1016/j.path.2016.05.006.
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  - Beeghly-Fadiel, Alicia, Hung N. Luu, Liping Du, Chanjuan Shi, Dauphne P. McGavic, Alexander A. Parikh, and Leon Raskin. “Early onset pancreatic malignancies: Clinical characteristics and survival associations.” Int J Cancer 139, no. 10 (November 15, 2016): 2169–77. https://doi.org/10.1002/ijc.30273.
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  - Weiss, Vivian, Julie Dueber, Jesse P. Wright, Justin Cates, Frank Revetta, Alexander A. Parikh, Nipun B. Merchant, and Chanjuan Shi. “Immunohistochemical analysis of the Wnt/β-catenin signaling pathway in pancreatic neuroendocrine neoplasms.” World J Gastrointest Oncol 8, no. 8 (August 15, 2016): 615–22. https://doi.org/10.4251/wjgo.v8.i8.615.
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  - Wheeler, Scott R., Chanjuan Shi, Jonathan A. Holt, and Cindy L. Vnencak-Jones. “Mutation profiles of synchronous colorectal cancers from a patient with Lynch syndrome suggest distinct oncogenic pathways.” J Gastrointest Oncol 7, no. 3 (June 2016): E64–71. https://doi.org/10.21037/jgo.2016.01.07.
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  - Su, Y., J. Li, C. Shi, R. H. Hruban, and G. L. Radice. “N-cadherin functions as a growth suppressor in a model of K-ras-induced PanIN.” Oncogene 35, no. 25 (June 2016): 3335–41. https://doi.org/10.1038/onc.2015.382.
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  - Deppen, Stephen A., Eric Liu, Jeffrey D. Blume, Jeffrey Clanton, Chanjuan Shi, Laurie B. Jones-Jackson, Vipul Lakhani, et al. “Safety and Efficacy of 68Ga-DOTATATE PET/CT for Diagnosis, Staging, and Treatment Management of Neuroendocrine Tumors.” J Nucl Med 57, no. 5 (May 2016): 708–14. https://doi.org/10.2967/jnumed.115.163865.
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  - Gonzalez, Raul S., Justin M. M. Cates, Mary Kay Washington, Robert Daniel Beauchamp, Robert J. Coffey, and Chanjuan Shi. “Adenoma-like adenocarcinoma: a subtype of colorectal carcinoma with good prognosis, deceptive appearance on biopsy and frequent KRAS mutation.” Histopathology 68, no. 2 (January 2016): 183–90. https://doi.org/10.1111/his.12725.
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  - Nagathihalli, Nagaraj S., Jason A. Castellanos, Chanjuan Shi, Yugandhar Beesetty, Michelle L. Reyzer, Richard Caprioli, Xi Chen, et al. “Signal Transducer and Activator of Transcription 3, Mediated Remodeling of the Tumor Microenvironment Results in Enhanced Tumor Drug Delivery in a Mouse Model of Pancreatic Cancer.” Gastroenterology 149, no. 7 (December 2015): 1932-1943.e9. https://doi.org/10.1053/j.gastro.2015.07.058.
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  - Salaria, Safia, Anna Means, Frank Revetta, Kamran Idrees, Eric Liu, and Chanjuan Shi. “Expression of CD24, a Stem Cell Marker, in Pancreatic and Small Intestinal Neuroendocrine Tumors.” Am J Clin Pathol 144, no. 4 (October 2015): 642–48. https://doi.org/10.1309/AJCPMZY5P9TWNJJV.
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  - Gonzalez, Raul S., David A. Schwartz, and Chanjuan Shi. “Colestipol granules in the colon: macroscopic and microscopic findings.” Histopathology 67, no. 1 (July 2015): 141–42. https://doi.org/10.1111/his.12618.
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  - Sopha, Sabrina C., Flavia G. N. Rosado, J. J. Smith, Nipun B. Merchant, and Chanjuan Shi. “Hepatic uterus-like mass misdiagnosed as hepatic abscess.” Int J Surg Pathol 23, no. 2 (April 2015): 134–39. https://doi.org/10.1177/1066896914534465.
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  - Wang, Yang, Chanjuan Shi, Yuanyuan Lu, Emily J. Poulin, Jeffery L. Franklin, and Robert J. Coffey. “Loss of Lrig1 leads to expansion of Brunner glands followed by duodenal adenomas with gastric metaplasia.” Am J Pathol 185, no. 4 (April 2015): 1123–34. https://doi.org/10.1016/j.ajpath.2014.12.014.
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  - Marincola, Paula, Raul S. Gonzalez, Chanjuan Shi, Benjamin Poulose, and Alexander Parikh. “Cholangiocarcinoma arising from intraductal papillary mucinous neoplasm of the bile duct.” Am Surg 81, no. 3 (March 2015): E102–3.
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  - Shi, Chanjuan, Raul S. Gonzalez, Zhiguo Zhao, Tatsuki Koyama, Toby C. Cornish, Kenneth R. Hande, Ronald Walker, Martin Sandler, Jordan Berlin, and Eric H. Liu. “Liver metastases of small intestine neuroendocrine tumors: Ki-67 heterogeneity and World Health Organization grade discordance with primary tumors.” Am J Clin Pathol 143, no. 3 (March 2015): 398–404. https://doi.org/10.1309/AJCPQ55SKOCYFZHN.
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  - Johnson, Adam, Jesse P. Wright, Zhiguo Zhao, Tatsuki Komaya, Alexander Parikh, Nipun Merchant, and Chanjuan Shi. “Cadherin 17 is frequently expressed by 'sclerosing variant' pancreatic neuroendocrine tumour.” Histopathology 66, no. 2 (January 2015): 225–33. https://doi.org/10.1111/his.12535.
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  - Chmielecki, Juliann, Katherine E. Hutchinson, Garrett M. Frampton, Zachary R. Chalmers, Adrienne Johnson, Chanjuan Shi, Julia Elvin, et al. “Comprehensive genomic profiling of pancreatic acinar cell carcinomas identifies recurrent RAF fusions and frequent inactivation of DNA repair genes.” Cancer Discov 4, no. 12 (December 2014): 1398–1405. https://doi.org/10.1158/2159-8290.CD-14-0617.
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  - Wu, Chia-Yen C., Eileen S. Carpenter, Kenneth K. Takeuchi, Christopher J. Halbrook, Louise V. Peverley, Harold Bien, Jason C. Hall, et al. “PI3K regulation of RAC1 is required for KRAS-induced pancreatic tumorigenesis in mice.” Gastroenterology 147, no. 6 (December 2014): 1405-16.e7. https://doi.org/10.1053/j.gastro.2014.08.032.
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  - Choi, Eunyoung, Joseph T. Roland, Brittney J. Barlow, Ryan O’Neal, Amy E. Rich, Ki Taek Nam, Chanjuan Shi, and James R. Goldenring. “Cell lineage distribution atlas of the human stomach reveals heterogeneous gland populations in the gastric antrum.” Gut 63, no. 11 (November 2014): 1711–20. https://doi.org/10.1136/gutjnl-2013-305964.
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  - Kiernan, Colleen M., Liping Du, Xi Chen, James T. Broome, Chanjuan Shi, Mary F. Peters, and Carmen C. Solorzano. “Predictors of hemodynamic instability during surgery for pheochromocytoma.” Ann Surg Oncol 21, no. 12 (November 2014): 3865–71. https://doi.org/10.1245/s10434-014-3847-7.
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  - Shi, Chanjuan, and David S. Klimstra. “Pancreatic neuroendocrine tumors: pathologic and molecular characteristics.” Semin Diagn Pathol 31, no. 6 (November 2014): 498–511. https://doi.org/10.1053/j.semdp.2014.08.008.
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  - James, Samuel D., Paul E. Wise, Tania Zuluaga-Toro, David A. Schwartz, M Kay Washington, and Chanjuan Shi. “Identification of pathologic features associated with "ulcerative colitis-like" Crohn's disease.” World J Gastroenterol 20, no. 36 (September 28, 2014): 13139–45. https://doi.org/10.3748/wjg.v20.i36.13139.
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  - Gonzalez, Raul S., Eric H. Liu, JoAnn R. Alvarez, Gregory D. Ayers, M Kay Washington, and Chanjuan Shi. “Should mesenteric tumor deposits be included in staging of well-differentiated small intestine neuroendocrine tumors?” Mod Pathol 27, no. 9 (September 2014): 1288–95. https://doi.org/10.1038/modpathol.2013.232.
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  - González, Raul S., Cindy L. Vnencak-Jones, Chanjuan Shi, and Oluwole Fadare. “Endomyometriosis ("Uterus-like mass") in an XY Male: Case Report With Molecular Confirmation and Literature Review.” Int J Surg Pathol 22, no. 5 (August 2014): 421–26. https://doi.org/10.1177/1066896913501385.
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  - Mikhitarian, Kaidi, Maressa Pollen, Zhiguo Zhao, Yu Shyr, Nipun B. Merchant, Alexander Parikh, Frank Revetta, M Kay Washington, Cindy Vnencak-Jones, and Chanjuan Shi. “Epidermal growth factor receptor signaling pathway is frequently altered in ampullary carcinoma at protein and genetic levels.” Mod Pathol 27, no. 5 (May 2014): 665–74. https://doi.org/10.1038/modpathol.2013.185.
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  - Pekala, Kelly R., Xidi Ma, Peter A. Kropp, Christine P. Petersen, Courtney W. Hudgens, Christine H. Chung, Chanjuan Shi, et al. “Loss of HNF6 expression correlates with human pancreatic cancer progression.” Lab Invest 94, no. 5 (May 2014): 517–27. https://doi.org/10.1038/labinvest.2014.47.
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  - Catanzaro, Joseph M., Namratha Sheshadri, Ji-An Pan, Yu Sun, Chanjuan Shi, Jinyu Li, R Scott Powers, Howard C. Crawford, and Wei-Xing Zong. “Oncogenic Ras induces inflammatory cytokine production by upregulating the squamous cell carcinoma antigens SerpinB3/B4.” Nat Commun 5 (April 23, 2014): 3729. https://doi.org/10.1038/ncomms4729.
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  - Shi, Chanjuan, M Kay Washington, Rupesh Chaturvedi, Yiannis Drosos, Frank L. Revetta, Connie J. Weaver, Emily Buzhardt, et al. “Fibrogenesis in pancreatic cancer is a dynamic process regulated by macrophage-stellate cell interaction.” Lab Invest 94, no. 4 (April 2014): 409–21. https://doi.org/10.1038/labinvest.2014.10.
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  - Matthaei, Hanno, Jian Wu, Marco Dal Molin, Chanjuan Shi, Sven Perner, Glen Kristiansen, Philipp Lingohr, et al. “GNAS sequencing identifies IPMN-specific mutations in a subgroup of diminutive pancreatic cysts referred to as "incipient IPMNs".” Am J Surg Pathol 38, no. 3 (March 2014): 360–63. https://doi.org/10.1097/PAS.0000000000000117.
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  - Ellison, Trevor A., Christopher L. Wolfgang, Chanjuan Shi, John L. Cameron, Peter Murakami, Liew Jun Mun, Aatur D. Singhi, et al. “A single institution's 26-year experience with nonfunctional pancreatic neuroendocrine tumors: a validation of current staging systems and a new prognostic nomogram.” Ann Surg 259, no. 2 (February 2014): 204–12. https://doi.org/10.1097/SLA.0b013e31828f3174.
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  - Shi, Chanjuan, Nipun Merchant, Guy Newsome, David M. Goldenberg, and David V. Gold. “Differentiation of pancreatic ductal adenocarcinoma from chronic pancreatitis by PAM4 immunohistochemistry.” Arch Pathol Lab Med 138, no. 2 (February 2014): 220–28. https://doi.org/10.5858/arpa.2013-0056-OA.
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  - Yachimski, Patrick, Chanjuan Shi, James C. Slaughter, and Mary Kay Washington. “Endoscopic mucosal resection of Barrett's esophagus detects high prevalence of subsquamous intestinal metaplasia.” World J Gastrointest Endosc 5, no. 12 (December 16, 2013): 590–94. https://doi.org/10.4253/wjge.v5.i12.590.
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  - Chi, M., K. Mikhitarian, C. Shi, and L. W. Goff. “Management of combined hepatocellular-cholangiocarcinoma: A case report and literature review.” Gastrointestinal Cancer Research 5, no. 6 (November 1, 2013): 199–202.
  - McCall, Chad M., Chanjuan Shi, Toby C. Cornish, David S. Klimstra, Laura H. Tang, Olca Basturk, Liew Jun Mun, et al. “Grading of well-differentiated pancreatic neuroendocrine tumors is improved by the inclusion of both Ki67 proliferative index and mitotic rate.” Am J Surg Pathol 37, no. 11 (November 2013): 1671–77. https://doi.org/10.1097/PAS.0000000000000089.
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  - Ayers, Katie, Chanjuan Shi, Kay Washington, and Patrick Yachimski. “Expert pathology review and endoscopic mucosal resection alters the diagnosis of patients referred to undergo therapy for Barrett's esophagus.” Surg Endosc 27, no. 8 (August 2013): 2836–40. https://doi.org/10.1007/s00464-013-2830-x.
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  - O’Neal, Ryan L., Ki Taek Nam, Bonnie J. LaFleur, Brittney Barlow, Koji Nozaki, Hyuk-Joon Lee, Woo Ho Kim, et al. “Human epididymis protein 4 is up-regulated in gastric and pancreatic adenocarcinomas.” Hum Pathol 44, no. 5 (May 2013): 734–42. https://doi.org/10.1016/j.humpath.2012.07.017.
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  - Kawamoto, Satomi, Pamela T. Johnson, Chanjuan Shi, Aatur D. Singhi, Ralph H. Hruban, Christopher L. Wolfgang, Barish H. Edil, and Elliot K. Fishman. “Pancreatic neuroendocrine tumor with cystlike changes: evaluation with MDCT.” Ajr Am J Roentgenol 200, no. 3 (March 2013): W283–90. https://doi.org/10.2214/AJR.12.8941.
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  - Sopha, Sabrina C., Purva Gopal, Nipun B. Merchant, Frank L. Revetta, David V. Gold, Kay Washington, and Chanjuan Shi. “Diagnostic and therapeutic implications of a novel immunohistochemical panel detecting duodenal mucosal invasion by pancreatic ductal adenocarcinoma.” Int J Clin Exp Pathol 6, no. 11 (2013): 2476–86.
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  - Singhi, Aatur D., Linda C. Chu, Armanda D. Tatsas, Chanjuan Shi, Trevor A. Ellison, Elliot K. Fishman, Satomi Kawamoto, et al. “Cystic pancreatic neuroendocrine tumors: a clinicopathologic study.” Am J Surg Pathol 36, no. 11 (November 2012): 1666–73. https://doi.org/10.1097/PAS.0b013e31826a0048.
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  - Deery, Sarah, Robert Yates, Jessica Hata, Chanjuan Shi, and Alexander A. Parikh. “Gastric adenocarcinoma associated with gastritis cystica profunda in an unoperated stomach.” Am Surg 78, no. 8 (August 2012): E379–80.
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  - McCall, Chad M., Chanjuan Shi, Alison P. Klein, Björn Konukiewitz, Barish H. Edil, Trevor A. Ellison, Christopher L. Wolfgang, Richard D. Schulick, Günter Klöppel, and Ralph H. Hruban. “Serotonin expression in pancreatic neuroendocrine tumors correlates with a trabecular histologic pattern and large duct involvement.” Hum Pathol 43, no. 8 (August 2012): 1169–76. https://doi.org/10.1016/j.humpath.2011.09.014.
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  - Shi, Chanjuan, and Kay Washington. “Molecular testing in colorectal cancer: diagnosis of Lynch syndrome and personalized cancer medicine.” Am J Clin Pathol 137, no. 6 (June 2012): 847–59. https://doi.org/10.1309/AJCPI83DINULUJNI.
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  - Yachida, Shinichi, Efsevia Vakiani, Catherine M. White, Yi Zhong, Tyler Saunders, Richard Morgan, Roeland F. de Wilde, et al. “Small cell and large cell neuroendocrine carcinomas of the pancreas are genetically similar and distinct from well-differentiated pancreatic neuroendocrine tumors.” Am J Surg Pathol 36, no. 2 (February 2012): 173–84. https://doi.org/10.1097/PAS.0b013e3182417d36.
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  - Shi, Chanjuan, and Ralph H. Hruban. “Intraductal papillary mucinous neoplasm.” Hum Pathol 43, no. 1 (January 2012): 1–16. https://doi.org/10.1016/j.humpath.2011.04.003.
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  - Kawamoto, Satomi, Chanjuan Shi, Ralph H. Hruban, Michael A. Choti, Richard D. Schulick, Elliot K. Fishman, and Stanley S. Siegelman. “Small serotonin-producing neuroendocrine tumor of the pancreas associated with pancreatic duct obstruction.” Ajr Am J Roentgenol 197, no. 3 (September 2011): W482–88. https://doi.org/10.2214/AJR.10.5428.
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  - Park, J. Y., T. C. Cornish, D. Lam-Himlin, C. Shi, and E. Montgomery. “In response.” American Journal of Surgical Pathology 35, no. 8 (August 1, 2011): 1244–45. https://doi.org/10.1097/PAS.0b013e31821e898c.
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  - Heaphy, Christopher M., Roeland F. de Wilde, Yuchen Jiao, Alison P. Klein, Barish H. Edil, Chanjuan Shi, Chetan Bettegowda, et al. “Altered telomeres in tumors with ATRX and DAXX mutations.” Science 333, no. 6041 (July 22, 2011): 425. https://doi.org/10.1126/science.1207313.
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  - Meriden, Zina, Chanjuan Shi, Barish H. Edil, Trevor Ellison, Christopher L. Wolfgang, Toby C. Cornish, Richard D. Schulick, and Ralph H. Hruban. “Hyaline globules in neuroendocrine and solid-pseudopapillary neoplasms of the pancreas: a clue to the diagnosis.” Am J Surg Pathol 35, no. 7 (July 2011): 981–88. https://doi.org/10.1097/PAS.0b013e31821a9a14.
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  - Jiao, Yuchen, Chanjuan Shi, Barish H. Edil, Roeland F. de Wilde, David S. Klimstra, Anirban Maitra, Richard D. Schulick, et al. “DAXX/ATRX, MEN1, and mTOR pathway genes are frequently altered in pancreatic neuroendocrine tumors.” Science 331, no. 6021 (March 4, 2011): 1199–1203. https://doi.org/10.1126/science.1200609.
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  - Xiong, Wei, and Chanjuan Shi. “Images in clinical medicine. Malignant pericardial effusion.” N Engl J Med 364, no. 9 (March 3, 2011): e18. https://doi.org/10.1056/NEJMicm1009066.
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  - Hong, Seung-Mo, Christopher M. Heaphy, Chanjuan Shi, Soo-Heang Eo, HyungJun Cho, Alan K. Meeker, James R. Eshleman, Ralph H. Hruban, and Michael Goggins. “Telomeres are shortened in acinar-to-ductal metaplasia lesions associated with pancreatic intraepithelial neoplasia but not in isolated acinar-to-ductal metaplasias.” Mod Pathol 24, no. 2 (February 2011): 256–66. https://doi.org/10.1038/modpathol.2010.181.
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  - Kern, Scott E., Chanjuan Shi, and Ralph H. Hruban. “The complexity of pancreatic ductal cancers and multidimensional strategies for therapeutic targeting.” J Pathol 223, no. 2 (January 2011): 295–306. https://doi.org/10.1002/path.2813.
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  - Gold, David V., Michael Goggins, David E. Modrak, Guy Newsome, Mengling Liu, Chanjuan Shi, Ralph H. Hruban, and David M. Goldenberg. “Detection of early-stage pancreatic adenocarcinoma.” Cancer Epidemiol Biomarkers Prev 19, no. 11 (November 2010): 2786–94. https://doi.org/10.1158/1055-9965.EPI-10-0667.
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  - Lam-Himlin, Dora, Jason Y. Park, Toby C. Cornish, Chanjuan Shi, and Elizabeth Montgomery. “Morphologic characterization of syndromic gastric polyps.” Am J Surg Pathol 34, no. 11 (November 2010): 1656–62. https://doi.org/10.1097/PAS.0b013e3181f2b1f1.
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  - Park, Jason Y., Toby C. Cornish, Dora Lam-Himlin, Chanjuan Shi, and Elizabeth Montgomery. “Gastric lesions in patients with autoimmune metaplastic atrophic gastritis (AMAG) in a tertiary care setting.” Am J Surg Pathol 34, no. 11 (November 2010): 1591–98. https://doi.org/10.1097/PAS.0b013e3181f623af.
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  - Shi, Chanjuan, Stanley S. Siegelman, Satomi Kawamoto, Christopher L. Wolfgang, Richard D. Schulick, Anirban Maitra, and Ralph H. Hruban. “Pancreatic duct stenosis secondary to small endocrine neoplasms: a manifestation of serotonin production?” Radiology 257, no. 1 (October 2010): 107–14. https://doi.org/10.1148/radiol.10100046.
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  - Shi, Chanjuan, Jennifer R. Scudiere, Toby C. Cornish, Dora Lam-Himlin, Jason Y. Park, Michael R. Fox, and Elizabeth A. Montgomery. “Clear cell change in colonic tubular adenoma and corresponding colonic clear cell adenocarcinoma is associated with an altered mucin core protein profile.” Am J Surg Pathol 34, no. 9 (September 2010): 1344–50. https://doi.org/10.1097/PAS.0b013e3181ec0810.
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  - Kamiyama, Hirohiko, Mihoko Kamiyama, Seung-Mo Hong, Collins A. Karikari, Ming-Tseh Lin, Michael W. Borges, Margaret Griffith, et al. “In vivo and in vitro propagation of intraductal papillary mucinous neoplasms.” Lab Invest 90, no. 5 (May 2010): 665–73. https://doi.org/10.1038/labinvest.2010.51.
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  - Scudiere, Jennifer R., Chanjuan Shi, Ralph H. Hruban, Joseph M. Herman, Elliot K. Fishman, Richard D. Schulick, Christopher L. Wolfgang, et al. “Sclerosing mesenteritis involving the pancreas: a mimicker of pancreatic cancer.” Am J Surg Pathol 34, no. 4 (April 2010): 447–53. https://doi.org/10.1097/PAS.0b013e3181d325c0.
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  - Shi, Chanjuan, Alison P. Klein, Michael Goggins, Anirban Maitra, Marcia Canto, Syed Ali, Richard Schulick, Emily Palmisano, and Ralph H. Hruban. “Increased Prevalence of Precursor Lesions in Familial Pancreatic Cancer Patients.” Clin Cancer Res 15, no. 24 (December 15, 2009): 7737–43. https://doi.org/10.1158/1078-0432.CCR-09-0004.
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  - Shi, Chanjuan, Arjun Chandrasekaran, Paul J. Thuluvath, Collins Karikari, Pedram Argani, Michael Goggins, Anirban Maitra, and James R. Eshleman. “Ultrasensitive detection of KRAS2 mutations in bile and serum from patients with biliary tract carcinoma using LigAmp technology.” J Mol Diagn 11, no. 6 (November 2009): 583–89. https://doi.org/10.2353/jmoldx.2009.090061.
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  - Koorstra, Jan-Bart M., Seung-Mo Hong, Chanjuan Shi, Alan K. Meeker, Ji Kon Ryu, George Johan A. Offerhaus, Michael G. Goggins, Ralph H. Hruban, and Anirban Maitra. “Widespread activation of the DNA damage response in human pancreatic intraepithelial neoplasia.” Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc 22, no. 11 (November 2009): 1439–45. https://doi.org/10.1038/modpathol.2009.114.
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  - Taube, Janis M., Shanaz Begum, Chanjuan Shi, James R. Eshleman, and William H. Westra. “Benign nodal nevi frequently harbor the activating V600E BRAF mutation.” Am J Surg Pathol 33, no. 4 (April 2009): 568–71. https://doi.org/10.1097/PAS.0b013e31818a64fb.
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  - Shi, Chanjuan, Ralph H. Hruban, and Alison P. Klein. “Familial pancreatic cancer.” Arch Pathol Lab Med 133, no. 3 (March 2009): 365–74. https://doi.org/10.5858/133.3.365.
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  - Chanjuan Shi, Pedram, and Pedram Argani. “Synchronous primary perianal Paget's disease and rectal adenocarcinoma: report of a hitherto undescribed phenomenon.” Int J Surg Pathol 17, no. 1 (February 2009): 42–45. https://doi.org/10.1177/1066896908316069.
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  - Shi, Chanjuan, Seung-Mo Hong, Phillip Lim, Hirohiko Kamiyama, Mehtab Khan, Robert A. Anders, Michael Goggins, Ralph H. Hruban, and James R. Eshleman. “KRAS2 mutations in human pancreatic acinar-ductal metaplastic lesions are limited to those with PanIN: implications for the human pancreatic cancer cell of origin.” Mol Cancer Res 7, no. 2 (February 2009): 230–36. https://doi.org/10.1158/1541-7786.MCR-08-0206.
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  - Shi, Chanjuan, Jason A. Daniels, and Ralph H. Hruban. “Molecular characterization of pancreatic neoplasms.” Adv Anat Pathol 15, no. 4 (July 2008): 185–95. https://doi.org/10.1097/PAP.0b013e31817bf57d.
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  - Shi, Chanjuan, Noriyoshi Fukushima, Tadayoshi Abe, Yansong Bian, Li Hua, Brian J. Wendelburg, Charles J. Yeo, Ralph H. Hruban, Michael G. Goggins, and James R. Eshleman. “Sensitive and quantitative detection of KRAS2 gene mutations in pancreatic duct juice differentiates patients with pancreatic cancer from chronic pancreatitis, potential for early detection.” Cancer Biol Ther 7, no. 3 (March 2008): 353–60. https://doi.org/10.4161/cbt.7.3.5362.
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  - Shi, Chanjuan, Antony R. Parker, Li Hua, Craig N. Morrell, Soo Chin Lee, Viswanath Bandaru, J Stephen Dumler, T. C. Wu, and James R. Eshleman. “Anti-gene padlocks eliminate Escherichia coli based on their genotype.” J Antimicrob Chemother 61, no. 2 (February 2008): 262–72. https://doi.org/10.1093/jac/dkm482.
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  - Rogers, Carmelle D., Noriyoshi Fukushima, Norihiro Sato, Chanjuan Shi, Nijaguna Prasad, Steven R. Hustinx, Hiroyuki Matsubayashi, et al. “Differentiating pancreatic lesions by microarray and QPCR analysis of pancreatic juice RNAs.” Cancer Biol Ther 5, no. 10 (October 2006): 1383–89. https://doi.org/10.4161/cbt.5.10.3323.
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  - Church, Jessica D., Dana Jones, Tamara Flys, Donald Hoover, Natalia Marlowe, Shu Chen, Chanjuan Shi, et al. “Sensitivity of the ViroSeq HIV-1 genotyping system for detection of the K103N resistance mutation in HIV-1 subtypes A, C, and D.” J Mol Diagn 8, no. 4 (September 2006): 430–32. https://doi.org/10.2353/jmoldx.2006.050148.
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  - Bertolesi, G. E., R. Walia Da Silva, C. A. B. Jollimore, C. Shi, S. Barnes, and M. E. M. Kelly. “Ca(v)3.1 splice variant expression during neuronal differentiation of Y-79 retinoblastoma cells.” Neuroscience 141, no. 1 (August 11, 2006): 259–68. https://doi.org/10.1016/j.neuroscience.2006.03.067.
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  - Rubio-Viqueira, Belen, Antonio Jimeno, George Cusatis, Xianfeng Zhang, Christine Iacobuzio-Donahue, Collins Karikari, Chanjusn Shi, et al. “An in vivo platform for translational drug development in pancreatic cancer.” Clin Cancer Res 12, no. 15 (August 1, 2006): 4652–61. https://doi.org/10.1158/1078-0432.CCR-06-0113.
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  - Parker, Antony R., Oliver M. Sieber, Chanjuan Shi, Li Hua, Masashi Takao, Ian P. Tomlinson, and James R. Eshleman. “Cells with pathogenic biallelic mutations in the human MUTYH gene are defective in DNA damage binding and repair.” Carcinogenesis 26, no. 11 (November 2005): 2010–18. https://doi.org/10.1093/carcin/bgi166.
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  - Flys, Tamara, Dwight V. Nissley, Cassidy W. Claassen, Dana Jones, Chanjuan Shi, Laura A. Guay, Philippa Musoke, et al. “Sensitive drug-resistance assays reveal long-term persistence of HIV-1 variants with the K103N nevirapine (NVP) resistance mutation in some women and infants after the administration of single-dose NVP: HIVNET 012.” J Infect Dis 192, no. 1 (July 1, 2005): 24–29. https://doi.org/10.1086/430742.
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  - Vessey, John P., Chanjuan Shi, Christine Ab Jollimore, Kelly T. Stevens, Miguel Coca-Prados, Steven Barnes, and Melanie Em Kelly. “Hyposmotic activation of ICl,swell in rabbit nonpigmented ciliary epithelial cells involves increased ClC-3 trafficking to the plasma membrane.” Biochem Cell Biol 82, no. 6 (December 2004): 708–18. https://doi.org/10.1139/o04-107.
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  - Shi, Chanjuan, Susan H. Eshleman, Dana Jones, Noriyoshi Fukushima, Li Hua, Antony R. Parker, Charles J. Yeo, Ralph H. Hruban, Michael G. Goggins, and James R. Eshleman. “LigAmp for sensitive detection of single-nucleotide differences.” Nat Methods 1, no. 2 (November 2004): 141–47. https://doi.org/10.1038/nmeth713.
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  - Shi, Chanjuan, Anna Szczesniak, Lucy Mao, Christine Jollimore, Miguel Coca-Prados, Orlando Hung, and Melanie E. M. Kelly. “A3 adenosine and CB1 receptors activate a PKC-sensitive Cl- current in human nonpigmented ciliary epithelial cells via a G beta gamma-coupled MAPK signaling pathway.” Br J Pharmacol 139, no. 3 (June 2003): 475–86. https://doi.org/10.1038/sj.bjp.0705266.
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  - Bertolesi, Gabriel E., Christine A. B. Jollimore, Chanjuan Shi, Lindsy Elbaum, Eileen M. Denovan-Wright, Steven Barnes, and Melanie E. M. Kelly. “Regulation of alpha1G T-type calcium channel gene (CACNA1G) expression during neuronal differentiation.” Eur J Neurosci 17, no. 9 (May 2003): 1802–10. https://doi.org/10.1046/j.1460-9568.2003.02618.x.
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  - Bertolesi, Gabriel E., Chanjuan Shi, Lindsy Elbaum, Christine Jollimore, Gabriela Rozenberg, Steven Barnes, and Melanie E. M. Kelly. “The Ca(2+) channel antagonists mibefradil and pimozide inhibit cell growth via different cytotoxic mechanisms.” Mol Pharmacol 62, no. 2 (August 2002): 210–19. https://doi.org/10.1124/mol.62.2.210.
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  - Thoreson, Wallace B., Jennifer S. Ryan, Chanjuan Shi, Melanie E. Kelly, Eric J. Bryson, Myron L. Toews, Tracy L. Ediger, and David M. Chacko. “Lysophosphatidic acid receptor signaling in mammalian retinal pigment epithelial cells.” Investigative Ophthalmology & Visual Science 43, no. 7 (July 2002): 2450–61.
  - Shi, Chanjuan, Steven Barnes, Miguel Coca-Prados, and Melanie E. M. Kelly. “Protein tyrosine kinase and protein phosphatase signaling pathways regulate volume-sensitive chloride currents in a nonpigmented ciliary epithelial cell line.” Invest Ophthalmol Vis Sci 43, no. 5 (May 2002): 1525–32.
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  - Ryan, J. S., C. Shi, and M. E. Kelly. “Patch-clamp recording methods for examining adrenergic regulation of potassium currents in ocular epithelial cells.” Methods Mol Biol 126 (2000): 391–407. https://doi.org/10.1385/1-59259-684-3:391.
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  - Shi, C., J. S. Ryan, A. S. French, M. Coca-Prados, and M. E. Kelly. “Hyposmotically activated chloride channels in cultured rabbit non-pigmented ciliary epithelial cells.” J Physiol 521 Pt 1 (November 15, 1999): 57–67. https://doi.org/10.1111/j.1469-7793.1999.00057.x.
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- Book Sections
  - Klimstra, D., N. Adsay, R. H. Hruban, G. Rindi, A. Couvelard, S. La Rosa, A. D. Singhi, et al. “Neuroendocrine Neoplasms, Pancreas.” In Digestive System Tumours. Who Press, 2019.
  - Shi, Chanjuan, E. Woltering, D. T. Beyer, D. Klimstra, K. Malin, E. Bergsland, and K. Washington. “Neuroendocrine tumors of the colon and the rectum.” In AJCC Cancer Staging Manual, edited by A. B. Amin. Springer, 2018.
  - Shi, Chanjuan, and J. S. Thomas. “Molecular testing in colorectal cancer.” In Diagnostic Molecular Pathology A Guide to Applied Molecular Testing, edited by W. Coleman and G. Tsongalis. Academic Press, 2016.
  - Shi, Chanjuan, and Kay Washington. “Gastrointestinal Neuroendocrine Tumors.” In Color Atlas and Synopsis: Gastrointestinal Pathology, edited by S. Y. Xiao. McGraw Hill Professional, 2015.
  - Shi, Chanjuan, and Kay Washington. “Manifestations of immunodeficiency in the gastrointestinal tract.” In Odze and Goldblum Surgical Pathology of the GI Tract, Liver, Biliary Tract and Pancreas Expert Consult - Online and Print, edited by R. Odze and J. Goldblum. Saunders, 2014.
  - Shi, C., and M. K. Washington. “Gastrointestinal and hepatic involvement in immunodeficiencies and systemic disease of childhood.” In Pathology of Pediatric Gastrointestinal and Liver Disease, 155–95, 2014. https://doi.org/10.1007/978-3-642-54053-0_5.
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  - Shi, C., and E. Liu. “Anatomy, Histology, and Function of the Pancreas.” In Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease Mechanisms, 2229–42, 2014. https://doi.org/10.1016/B978-0-12-386456-7.04902-9.
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  - Wentz, S. C., and C. Shi. “Pancreatic Cancer and Its Precursor Lesions.” In Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease Mechanisms, 2251–64, 2014. https://doi.org/10.1016/B978-0-12-386456-7.04904-2.
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  - Shi, C., J. S. Macdonald, and J. D. Berlin. “Unusual Cancers of the Pancreas.” In Textbook of Uncommon Cancer, 409–21, 2012. https://doi.org/10.1002/9781118464557.ch29.
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  - Shi, Chanjuan, E. A. Montgomery, and C. A. Iacobuzio-Donahue. “Non-Neoplastic and Inflammatory Disorders of the Small Bowel.” In Gastrointestinal and Liver Pathology, edited by C. A. Iacobuzi-Donahue and E. A. Montgomery. Saunders, 2011.
- Conference Papers
  - Srinivasan, S., X. Dai, S. Mehra, C. Shi, R. Dawra, N. Merchant, M. VanSaun, and N. S. Nagathihalli. “CREB Activation is Regulated by CXCL12 in Chronic Pancreatitis.” In Pancreas, 48:1527–1527. LIPPINCOTT WILLIAMS & WILKINS, 2019.
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  - Khurram, Muhammad S., Won Jae Huh, and Chanjuan Shi. “Expression of Stem Cell Markers in the Histologic Sub-Types of Ampullary Carcinomas.” In Laboratory Investigation, 98:274–75. NATURE PUBLISHING GROUP, 2018.
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  - Roberts, Jordan Andrew, Raul S. Gonzalez, Frank Revetta, and Chanjuan Shi. “Mesenteric Tumor Deposits Arising from Small Intestinal Neuroendocrine Tumors are Frequently Associated with Sclerosis and IgG4-Expressing Plasma Cells.” In Modern Pathology, 31:298–298. NATURE PUBLISHING GROUP, 2018.
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  - Balko, Justin M., Daniel Y. Wang, Yu Wang, Rami Al-Rohil, Margaret Compton, Jeffery A. Sosman, Igor Puzanov, et al. “Abstract 588: Advanced molecular characterization of severe autoimmune toxicities associated with checkpoint inhibitor therapies.” In Clinical Research (Excluding Clinical Trials). American Association for Cancer Research, 2017. https://doi.org/10.1158/1538-7445.am2017-588.
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  - Gibson, William, Raul S. Gonzalez, Eric Liu, and Chanjuan Shi. “Microscopic Tumor Deposits in the Liver Are Frequently Present in Patients with Liver Metastases from Digestive Neuroendocrine Tumors.” In Modern Pathology, 30:172A-172A. NATURE PUBLISHING GROUP, 2017.
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  - Means, Anna L., Tanner J. Freeman, Connie J. Weaver, Chanjuan Shi, Mary K. Washington, Bronson C. Wessinger, Tasia Brown, et al. “Abstract A16: Smad4 pathways modulate induction of the chemokine Ccl20 and repress inflammation-induced carcinogenesis in mouse colon.” In Understanding the Origins of Colorectal Neoplasia. American Association for Cancer Research, 2017. https://doi.org/10.1158/1538-7445.crc16-a16.
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  - Lamichhane, P., N. S. Nagathihalli, J. Castellanos, C. Shi, C. Roberts, M. Vansaun, and N. Merchant. “MEK Resistance via Amphiregulin Mediated EGFR-STAT3 Activation in Pancreatic Cancer.” In Pancreas, 45:1518–1518. LIPPINCOTT WILLIAMS & WILKINS, 2016.
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  - Means, A. L., F. C. Pan, J. Kim, C. Shi, M. K. Washington, J. Kopp, M. Sander, M. Gannon, R. D. Beauchamp, and C. V. Wright. “Kras Mutation Imparts Neoplastic Potential on Duct Cells but Not Acinar Cells in a Mouse Model of Obstructive Chronic Pancreatitis.” In Pancreas, 45:1525–1525. LIPPINCOTT WILLIAMS & WILKINS, 2016.
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  - Srinivasan, S., C. Shi, C. Roberts, M. Vansaun, N. Merchant, and N. S. Nagathihalli. “Blocking DNA Damage Repair Improves Efficacy of Therapeutics in Pancreatic Cancer.” In Pancreas, 45:1539–1539. LIPPINCOTT WILLIAMS & WILKINS, 2016.
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  - Padmanabhan, C., E. Liu, K. Dahlman, J. Berlin, R. Gonzalez, Y. Guo, C. Shi, and K. Idrees. “Frequent BRAF Mutations in Colonic High-Grade Neuroendocrine Carcinoma.” In Annals of Surgical Oncology, 23:S92–93. SPRINGER, 2016.
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  - Wang, Y., C. L. Vnencak-Jones, and C. Shi. “Deciphering EMAST and MSI in Colorectal Cancers.” In Journal of Molecular Diagnostics, 17:819–819. ELSEVIER SCIENCE INC, 2015.
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  - Weiss, Vivian, Justin Cates, Alexander Parikh, Nipun Merchant, and Chanjuan Shi. “Expression of Wnt/Beta-Catenin Signaling Pathway in Pancreatic Neuroendocrine Neoplasms.” In Laboratory Investigation, 95:198A-198A. NATURE PUBLISHING GROUP, 2015.
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  - Catanzaro, Joseph, Namratha Sheshadri, Ji-An Pan, Yu Sun, Chanjuan Shi, Jinyu Li, Scott Powers, Howard Crawford, and Wei-Xing Zong. “Abstract A23: Oncogenic Ras induces inflammatory cytokine production by upregulating squamous cell carcinoma antigen (SerpinB3).” In Ras Effectors Basic Biology. American Association for Cancer Research, 2014. https://doi.org/10.1158/1557-3125.rasonc14-a23.
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  - Chmielecki, J., K. E. Hutchinson, G. M. Frampton, Z. R. Chalmers, A. Johnson, C. Shi, J. Elvin, et al. “250 Comprehensive genomic profiling of pancreatic acinar cell carcinomas identifies recurrent RAF fusions and frequent inactivation of DNA repair genes.” In European Journal of Cancer, 50:84–84. Elsevier BV, 2014. https://doi.org/10.1016/s0959-8049(14)70376-4.
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  - Nagathihalli, N., K. Honnenahally, H. Tanjore, F. Revetta, X. Chen, J. Castellanos, C. Shi, and N. Merchant. “Smoking-Induced DNA Damage Results in ATM-Dependent Phosphorylation of Histone H2AX in Pancreatic Cancer.” In Pancreas, 43:1394–1394. LIPPINCOTT WILLIAMS & WILKINS, 2014.
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  - Miller, Vincent A., Juliann Chmielecki, Katherine Hutchinson, Garrett Michael Frampton, Siraj M. Ali, Jeffrey S. Ross, Chanjuan Shi, et al. “Next-generation sequencing (NGS)-based profiling of pancreatic acinar cell carcinoma for identification of a recurrent SND1-BRAF fusion.” In Journal of Clinical Oncology, 32:11029–11029. American Society of Clinical Oncology (ASCO), 2014. https://doi.org/10.1200/jco.2014.32.15_suppl.11029.
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  - Shi, Chanjuan, Kenneth Hande, Ronald Walker, Martin Sandlers, Jordan Berlin, and Eric Liu. “Tumor Heterogeneity in Small Intestine Neuroendocrine Tumors Metastatic to the Liver.” In Pancreas, 43:504–504. LIPPINCOTT WILLIAMS & WILKINS, 2014.
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  - Basturk, Olca, Laura Tang, Ralph H. Hruban, Volkan Adsay, Zhaohai Yang, Alyssa M. Krasinskas, Efsevia Vakiani, et al. “Poorly differentiated neuroendocrine carcinomas of the pancreas: a clinicopathologic analysis of 44 cases.” In Am J Surg Pathol, 38:437–47, 2014. https://doi.org/10.1097/PAS.0000000000000169.
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  - Basturk, O., V. Adsay, R. H. Hruban, Z. Yang, T. J. Giordano, C. Shi, B. Saka, and D. S. Klimstra. “Pancreatic Acinar Cell Carcinomas with Prominent Neuroendocrine Differentiation: Clinicopathologic Analysis of a Distinct and Diagnostically Challenging Neoplasm.” In Modern Pathology, 27:447A-447A. NATURE PUBLISHING GROUP, 2014.
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  - Basturk, O., V. Adsay, R. H. Hruban, Z. Yang, T. J. Giordano, C. Shi, B. Saka, and D. S. Klimstra. “Pancreatic Acinar Cell Carcinomas with Prominent Neuroendocrine Differentiation: Clinicopathologic Analysis of a Distinct and Diagnostically Challenging Neoplasm.” In Laboratory Investigation, 94:447A-447A. NATURE PUBLISHING GROUP, 2014.
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  - Gonzalez, R. S., M. K. Washington, and C. Shi. “Clinical, Pathologic, and Molecular Features of Colorectal Carcinoma with Micropapillary Features.” In Laboratory Investigation, 94:175A-176A. NATURE PUBLISHING GROUP, 2014.
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  - Gonzalez, R. S., M. K. Washington, and C. Shi. “Adenoma-Like Adenocarcinoma: A Subtype of Colorectal Carcinoma with Good Prognosis, Deceptive Appearance on Biopsy, and Frequent KRAS Mutation.” In Laboratory Investigation, 94:175A-175A. NATURE PUBLISHING GROUP, 2014.
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  - Gonzalez, R. S., M. K. Washington, and C. Shi. “Clinical, Pathologic, and Molecular Features of Colorectal Carcinoma with Micropapillary Features.” In Modern Pathology, 27:175A-176A. NATURE PUBLISHING GROUP, 2014.
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  - Gonzalez, R. S., M. K. Washington, and C. Shi. “Adenoma-Like Adenocarcinoma: A Subtype of Colorectal Carcinoma with Good Prognosis, Deceptive Appearance on Biopsy, and Frequent KRAS Mutation.” In Modern Pathology, 27:175A-175A. NATURE PUBLISHING GROUP, 2014.
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  - Salaria, S. N., C. Shi, and K. Washington. “Histologic Spectrum of Bile Duct Injury in Prolonged Cholestatic Drug Reaction.” In Modern Pathology, 27:427A-427A. NATURE PUBLISHING GROUP, 2014.
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  - Salaria, S. N., C. Shi, and K. Washington. “Histologic Spectrum of Bile Duct Injury in Prolonged Cholestatic Drug Reaction.” In Laboratory Investigation, 94:427A-427A. NATURE PUBLISHING GROUP, 2014.
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  - Castellanos, J., N. Nagathihalli, E. McKinley, Y. Beesetty, C. Shi, H Charles Manning, and N. Merchant. “Imaging Modalities to Assay Molecular Biomarkers of Resistance in Pancreatic Cancer.” In Pancreas, 42:1341–1341. LIPPINCOTT WILLIAMS & WILKINS, 2013.
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  - Ciombor, Kristen Keon, Natasha G. Deane, Keeli B. Lewis, Xi Chen, Bing Zhang, Mary Kay Washington, Chanjuan Shi, and R Daniel Beauchamp. “Colorectal cancer gene expression profiling using nanostring nCounter analysis.” In Journal of Clinical Oncology, Vol. 31. AMER SOC CLINICAL ONCOLOGY, 2013.
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  - Liu, E., K. Mikhitarian, F. Revetta, and C. Shi. “Expression of Serotonin, FGF2, beta-Catenin, E-Cadherin and Cadherin 17 in Primary and Metastatic Well-Differentiated Neuroendocrine Tumors of the Small Intestine.” In Pancreas, 42:378–378. LIPPINCOTT WILLIAMS & WILKINS, 2013.
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  - Liu, E., K. Mikhitarian, F. Revetta, and C. Shi. “Activation of EGFR and c-Met Signaling Pathways in Well-Differentiated Neuroendocrine Tumors of the Small Intestine.” In Pancreas, 42:377–78. LIPPINCOTT WILLIAMS & WILKINS, 2013.
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  - Basturk, O., Z. Yang, L. H. Tang, R. Hruban, C. McCall, V. Adsay, A. Krasinskas, et al. “Increased (> 20%) Ki67 Proliferation Index in Morphologically Well Differentiated Pancreatic Neuroendocrine Tumors (PanNETs) Correlates with Decreased Overall Survival.” In Laboratory Investigation, 93:423A-423A. NATURE PUBLISHING GROUP, 2013.
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  - Basturk, O., Z. Yang, L. H. Tang, R. Hruban, C. McCall, V. Adsay, A. Krasinskas, et al. “Increased (> 20%) Ki67 Proliferation Index in Morphologically Well Differentiated Pancreatic Neuroendocrine Tumors (PanNETs) Correlates with Decreased Overall Survival.” In Modern Pathology, 26:423A-423A. NATURE PUBLISHING GROUP, 2013.
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  - Dueber, J. C., and C. Shi. “Nuclear Accumulation of beta-Catenin in Well-Differentiated Pancreatic Neuroendocrine Tumors from Patients with Familial Adenomatous Polyposis.” In Modern Pathology, 26:423A-423A. NATURE PUBLISHING GROUP, 2013.
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  - Dueber, J. C., and C. Shi. “Nuclear Accumulation of beta-Catenin in Well-Differentiated Pancreatic Neuroendocrine Tumors from Patients with Familial Adenomatous Polyposis.” In Laboratory Investigation, 93:423A-423A. NATURE PUBLISHING GROUP, 2013.
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  - Gilger, M. A., L. Cassani, E. Lindsey, F. Revetta, E. Liu, and C. Shi. “Well Differentiated Neuroendocrine Tumors of the Duodenum: A Clinicopathologic Profile and Somatostatin Receptor 2 Expression.” In Laboratory Investigation, 93:151A-151A. NATURE PUBLISHING GROUP, 2013.
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  - Gilger, M. A., L. Cassani, E. Lindsey, F. Revetta, E. Liu, and C. Shi. “Well Differentiated Neuroendocrine Tumors of the Duodenum: A Clinicopathologic Profile and Somatostatin Receptor 2 Expression.” In Modern Pathology, 26:151A-151A. NATURE PUBLISHING GROUP, 2013.
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  - Gonzalez, R. S., E. H. Liu, M. K. Washington, and C. Shi. “Should Mesenteric Tumor Deposits Be Included in Staging of Small Intestine Neuroendocrine Tumors?” In Laboratory Investigation, 93:151A-151A. NATURE PUBLISHING GROUP, 2013.
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  - Gonzalez, R. S., E. H. Liu, M. K. Washington, and C. Shi. “Should Mesenteric Tumor Deposits Be Included in Staging of Small Intestine Neuroendocrine Tumors?” In Modern Pathology, 26:151A-151A. NATURE PUBLISHING GROUP, 2013.
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  - Johnson, A. S., and C. Shi. “Intestinal Markers Are Expressed in Pancreatic Well-Differentiated Neuroendocrine Tumors and Associated with Sclerosing Variant.” In Laboratory Investigation, 93:426A-426A. NATURE PUBLISHING GROUP, 2013.
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  - Johnson, A. S., and C. Shi. “Intestinal Markers Are Expressed in Pancreatic Well-Differentiated Neuroendocrine Tumors and Associated with Sclerosing Variant.” In Modern Pathology, 26:426A-426A. NATURE PUBLISHING GROUP, 2013.
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  - McKinley, E. T., D. Tang, N. Merchant, C. Shi, H. L. Moses, and H. C. Manning. “Translocator protein (TSPO) as an imaging target in pancreatic cancer.” In Journal of Nuclear Medicine, 54:17–17. SOC NUCLEAR MEDICINE INC, 2013.
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  - Wentz, S. C., C. Shi, C. M. McCall, R. Sharma, and R. H. Hruban. “Tumor-Infiltrating Lymphocytes Do Not Affect Ki-67 Labeling Index in a Series of Pancreatic Neuroendocrine Tumors (PanNETs).” In Laboratory Investigation, 93:432A-433A. NATURE PUBLISHING GROUP, 2013.
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  - Wentz, S. C., C. Shi, C. M. McCall, R. Sharma, and R. H. Hruban. “Tumor-Infiltrating Lymphocytes Do Not Affect Ki-67 Labeling Index in a Series of Pancreatic Neuroendocrine Tumors (PanNETs).” In Modern Pathology, 26:432A-433A. NATURE PUBLISHING GROUP, 2013.
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  - Nagathihalli, N., Y. Beesetty, C. Shi, and N. Merchant. “Cross-Talk Between STAT3 and MAPK Signaling in Pancreatic Cancer.” In Pancreas, 41:1389–1389. LIPPINCOTT WILLIAMS & WILKINS, 2012.
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  - Shi, C., R. Chaturvedi, F. Revetta, K. T. Wilson, M. K. Washington, and A. L. Means. “The Pancreatic Tumor Microenvironment Comprises Discrete Domains and is Regulated by Crosstalk Between PSCs and Tissue Macrophages.” In Pancreas, 41:1403–1403. LIPPINCOTT WILLIAMS & WILKINS, 2012.
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  - Kawamoto, S., P. Johnson, C. Shi, R. Hruban, and E. Fishman. “Cystic Neuroendocrine Tumor of the Pancreas: CT Features and Differentiation From Other Pancreatic Cystic Masses.” In American Journal of Roentgenology, Vol. 198. AMER ROENTGEN RAY SOC, 2012.
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  - McCall, C. M., C. Shi, T. Ellison, R. H. Hruban, C. Wolfgang, R. Schulick, M. Choti, D. Klimstra, O. Basturk, and B. H. Edil. “Ki-67 Proliferation Index and Mitotic Rate Discordance in Pancreatic Neuroendocrine Tumors Correlates with Aggressive Histologic Features and Decreased Overall Survival.” In Laboratory Investigation, 92:446A-447A. NATURE PUBLISHING GROUP, 2012.
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  - McCall, C. M., C. Shi, T. Ellison, R. H. Hruban, C. Wolfgang, R. Schulick, M. Choti, D. Klimstra, O. Basturk, and B. H. Edil. “Ki-67 Proliferation Index and Mitotic Rate Discordance in Pancreatic Neuroendocrine Tumors Correlates with Aggressive Histologic Features and Decreased Overall Survival.” In Modern Pathology, 25:446A-447A. NATURE PUBLISHING GROUP, 2012.
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  - Mikhitarian, K., N. Merchant, F. Revetta, and C. Shi. “Expression of Amphiregulin, Epidermal Growth Factor Receptor (EGFR) and Phosphorylated EGFR in Ampullary Carcinoma.” In Modern Pathology, 25:447A-447A. NATURE PUBLISHING GROUP, 2012.
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  - Mikhitarian, K., N. Merchant, F. Revetta, and C. Shi. “Expression of Amphiregulin, Epidermal Growth Factor Receptor (EGFR) and Phosphorylated EGFR in Ampullary Carcinoma.” In Laboratory Investigation, 92:447A-447A. NATURE PUBLISHING GROUP, 2012.
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  - Pollen, M. T., C. L. Vnencak-Jones, K. Mikhitarian, N. Merchant, and C. Shi. “Mutational Profiling in Ampullary Adenocarcinomas Using the 'SNaPSHOT' Platform.” In Laboratory Investigation, 92:175A-176A. NATURE PUBLISHING GROUP, 2012.
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  - Pollen, M. T., C. L. Vnencak-Jones, K. Mikhitarian, N. Merchant, and C. Shi. “Mutational Profiling in Ampullary Adenocarcinomas Using the 'SNaPSHOT' Platform.” In Modern Pathology, 25:175A-176A. NATURE PUBLISHING GROUP, 2012.
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  - Wentz, S. C., P. Gopal, N. B. Merchant, F. L. Revetta, D. V. Gold, M. K. Washington, and C. Shi. “Detection of Duodenal Mucosal Invasion by Pancreatic Ductal Adenocarcinoma: A Novel Immunopanel with Prognostic and Therapeutic Implications.” In Laboratory Investigation, 92:185A-185A. NATURE PUBLISHING GROUP, 2012.
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  - Wentz, S. C., P. Gopal, N. B. Merchant, F. L. Revetta, D. V. Gold, M. K. Washington, and C. Shi. “Detection of Duodenal Mucosal Invasion by Pancreatic Ductal Adenocarcinoma: A Novel Immunopanel with Prognostic and Therapeutic Implications.” In Modern Pathology, 25:185A-185A. NATURE PUBLISHING GROUP, 2012.
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  - Liu, E., K. Mikhitarian, F. Revetta, and C. Shi. “Activation of EGFR and c-Met Signaling Pathways in Well-Differentiated Neuroendocrine Tumors of the Small Intestine.” In Neuroendocrinology, 96:9–9. KARGER, 2012.
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  - Liu, E., K. Mikhitarian, F. Revetta, and C. Shi. “Differential Expression of Markers in a Midgut Carcinoid Tissue Microarray.” In Neuroendocrinology, 96:8–8. KARGER, 2012.
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  - Nagathihalli, N. S., Y. Beesetty, M. Reyzer, C. Shi, R. Caprioli, and N. B. Merchant. “STAT3 Mediates Regulation of the Tumor Microenvironment in Pancreatic Cancer.” In Pancreas, 40:1342–1342. LIPPINCOTT WILLIAMS & WILKINS, 2011.
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  - Gopal, P., T. C. Cornish, N. B. Merchant, R. H. Hruban, and C. Shi. “Immunohistochemical Assessment of DCBLD2 and PDZD3 Expression in Pancreatic Ductal Adenocarcinoma.” In Laboratory Investigation, 91:360A-361A. NATURE PUBLISHING GROUP, 2011.
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  - Gopal, P., T. C. Cornish, N. B. Merchant, R. H. Hruban, and C. Shi. “Immunohistochemical Assessment of DCBLD2 and PDZD3 Expression in Pancreatic Ductal Adenocarcinoma.” In Modern Pathology, 24:360A-361A. NATURE PUBLISHING GROUP, 2011.
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  - McCall, C. M., C. Shi, A. P. Klein, G. Kloppel, B. Konukiewicz, B. H. Edil, T. Ellison, and R. H. Hruban. “Serotonin Expression in Pancreatic Neuroendocrine Tumors Correlates with a Trabecular Histologic Pattern and Fewer Lymph Node Metastases.” In Laboratory Investigation, 91:369A-369A. NATURE PUBLISHING GROUP, 2011.
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  - McCall, C. M., C. Shi, A. P. Klein, G. Kloppel, B. Konukiewicz, B. H. Edil, T. Ellison, and R. H. Hruban. “Serotonin Expression in Pancreatic Neuroendocrine Tumors Correlates with a Trabecular Histologic Pattern and Fewer Lymph Node Metastases.” In Modern Pathology, 24:369A-369A. NATURE PUBLISHING GROUP, 2011.
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  - Meriden, Z., C. Shi, B. Edil, T. Ellison, C. Wolfgang, R. Schulick, and R. H. Hruban. “Hyaline Globules in Neuroendocrine and Solid-Pseudopapillary Neoplasms of the Pancreas: A Clue to the Diagnosis.” In Laboratory Investigation, 91:369A-369A. NATURE PUBLISHING GROUP, 2011.
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  - Meriden, Z., C. Shi, B. Edil, T. Ellison, C. Wolfgang, R. Schulick, and R. H. Hruban. “Hyaline Globules in Neuroendocrine and Solid-Pseudopapillary Neoplasms of the Pancreas: A Clue to the Diagnosis.” In Modern Pathology, 24:369A-369A. NATURE PUBLISHING GROUP, 2011.
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  - Vnencak-Jones, C., Z. Su, L. Fohn, C. Coffin, A. Gonzalez, D. Itani, C. Shi, J. Sosman, and W. Pao. “A Personalized Medicine Approach to Lung Cancer and Melanoma.” In Laboratory Investigation, 91:447A-447A. NATURE PUBLISHING GROUP, 2011.
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  - Vnencak-Jones, C., Z. Su, L. Fohn, C. Coffin, A. Gonzalez, D. Itani, C. Shi, J. Sosman, and W. Pao. “A Personalized Medicine Approach to Lung Cancer and Melanoma.” In Modern Pathology, 24:447A-447A. NATURE PUBLISHING GROUP, 2011.
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  - Cornish, T. C., D. Lam-Himlin, J. Y. Park, C. Shi, and E. Montgomery. “Endoscopic Treatment Is Safe and Effective for High-Grade Dysplasia in Barrett's Esophagus.” In Modern Pathology, 23:141A-141A. NATURE PUBLISHING GROUP, 2010.
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  - Cornish, T. C., D. Lam-Himlin, J. Y. Park, C. Shi, and E. Montgomery. “Endoscopic Treatment Is Safe and Effective for High-Grade Dysplasia in Barrett's Esophagus.” In Laboratory Investigation, 90:141A-141A. NATURE PUBLISHING GROUP, 2010.
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  - Hong, S. -. M., C. M. Heaphy, C. Shi, H. J. Cho, A. K. Meeker, J. R. Eshleman, R. H. Hruban, and M. Goggins. “Telomeres Are Shortened in Acinar to Ductal Metaplasia (ADM) Lesions Associated with Pancreatic Intraepithelial Neoplasias (PanINs) but Not in Isolated ADMs.” In Modern Pathology, 23:148A-148A. NATURE PUBLISHING GROUP, 2010.
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  - Hong, S. -. M., C. M. Heaphy, C. Shi, H. J. Cho, A. K. Meeker, J. R. Eshleman, R. H. Hruban, and M. Goggins. “Telomeres Are Shortened in Acinar to Ductal Metaplasia (ADM) Lesions Associated with Pancreatic Intraepithelial Neoplasias (PanINs) but Not in Isolated ADMs.” In Laboratory Investigation, 90:148A-148A. NATURE PUBLISHING GROUP, 2010.
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  - Lam-Himlin, D., J. Y. Park, T. Cornish, C. Shi, and E. Montgomery. “Morphologic Characterization of Gastric Polyps in Juvenile Polyposis and Peutz-Jeghers' Syndromes Versus Gastric Hyperplastic Polyps.” In Laboratory Investigation, 90:152A-153A. NATURE PUBLISHING GROUP, 2010.
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  - Lam-Himlin, D., J. Y. Park, T. Cornish, C. Shi, and E. Montgomery. “Morphologic Characterization of Gastric Polyps in Juvenile Polyposis and Peutz-Jeghers' Syndromes Versus Gastric Hyperplastic Polyps.” In Modern Pathology, 23:152A-153A. NATURE PUBLISHING GROUP, 2010.
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  - Park, J. Y., T. Cornish, D. Lam-Himlin, C. Shi, and E. Montgomery. “Lesions Arising in the Setting of Autoimmune Metaplastic Atrophic Gastritis (AMAG) in an Urban Tertiary Care Setting.” In Modern Pathology, 23:161A-161A. NATURE PUBLISHING GROUP, 2010.
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  - Park, J. Y., T. Cornish, D. Lam-Himlin, C. Shi, and E. Montgomery. “Lesions Arising in the Setting of Autoimmune Metaplastic Atrophic Gastritis (AMAG) in an Urban Tertiary Care Setting.” In Laboratory Investigation, 90:161A-161A. NATURE PUBLISHING GROUP, 2010.
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  - Shi, C., J. R. Scudiere, T. Cornish, D. Lam-Himlin, J. Y. Park, and E. Montgomery. “"Clear Cell Change" in Colonic Tubular Adenoma and Corresponding Colonic Clear Cell Adenocarcinoma Is Associated with Decreased MUC2 and MUC5 Expression.” In Modern Pathology, 23:167A-167A. NATURE PUBLISHING GROUP, 2010.
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  - Shi, C., J. R. Scudiere, T. Cornish, D. Lam-Himlin, J. Y. Park, and E. Montgomery. “"Clear Cell Change" in Colonic Tubular Adenoma and Corresponding Colonic Clear Cell Adenocarcinoma Is Associated with Decreased MUC2 and MUC5 Expression.” In Laboratory Investigation, 90:167A-167A. NATURE PUBLISHING GROUP, 2010.
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  - Shi, C., S. S. Siegelman, S. Kawamoto, C. L. Wolfgang, R. D. Schulick, A. Maitra, and R. H. Hruban. “Dramatic Pancreatic Duct Strictures Secondary to Small Endocrine Neoplasms: A Manifestation of Serotonin Production?” In Modern Pathology, 23:371A-371A. NATURE PUBLISHING GROUP, 2010.
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  - Shi, C., S. S. Siegelman, S. Kawamoto, C. L. Wolfgang, R. D. Schulick, A. Maitra, and R. H. Hruban. “Dramatic Pancreatic Duct Strictures Secondary to Small Endocrine Neoplasms: A Manifestation of Serotonin Production?” In Laboratory Investigation, 90:371A-371A. NATURE PUBLISHING GROUP, 2010.
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  - Shi, C., A. P. Klein, M. Goggins, M. Canto, R. Schulick, E. Palmisano, and R. H. Hruban. “Patients with Familial Pancreatic Cancer Have More and Higher Grade Precursor Lesions Than Do Patients with Sporadic Pancreatic Cancer.” In Modern Pathology, 22:322A-322A. NATURE PUBLISHING GROUP, 2009.
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  - Shi, C., A. P. Klein, M. Goggins, M. Canto, R. Schulick, E. Palmisano, and R. H. Hruban. “Patients with Familial Pancreatic Cancer Have More and Higher Grade Precursor Lesions Than Do Patients with Sporadic Pancreatic Cancer.” In Laboratory Investigation, 89:322A-322A. NATURE PUBLISHING GROUP, 2009.
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  - Shi, C., S. -. M. Hong, P. Lim, J. R. Eshleman, M. Goggins, and R. H. Hruban. “Immunohistochemical and Molecular Characterization of Incipient Intraductal Papillary Mucinous Neoplasms.” In Laboratory Investigation, 89:321A-322A. NATURE PUBLISHING GROUP, 2009.
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  - Shi, C., S. -. M. Hong, P. Lim, J. R. Eshleman, M. Goggins, and R. H. Hruban. “Immunohistochemical and Molecular Characterization of Incipient Intraductal Papillary Mucinous Neoplasms.” In Modern Pathology, 22:321A-322A. NATURE PUBLISHING GROUP, 2009.
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  - Taube, J., W. Westra, S. Begum, C. Shi, and J. Eshleman. “BENIGN NODAL NEVI FREQUENTLY HARBOR THE ACTIVATING V600E BRAF MUTATION.” In Journal of Cutaneous Pathology, 36:108–108. WILEY-BLACKWELL PUBLISHING, INC, 2009.
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  - Shi, C., S. -. M. Hong, P. Lim, H. Kamiyama, A. Goggins, R. H. Hruban, and J. R. Eshleman. “KRAS2 gene mutations in acinar-ductal metaplasia in the pancreas: Pancreatic neoplasia may start prior to pancreatic Intraepithelial neoplasia lesions.” In Modern Pathology, 21:316A-316A. NATURE PUBLISHING GROUP, 2008.
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  - Shi, C., S. -. M. Hong, P. Lim, H. Kamiyama, M. Goggins, R. H. Hruban, and J. R. Eshleman. “KRAS2 gene mutations in acinar-ductal metaplasia in the pancreas: Pancreatic neoplasia may start prior to pancreatic intraepithelial neoplasia lesions.” In Laboratory Investigation, 88:316A-316A. NATURE PUBLISHING GROUP, 2008.
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  - Shi, C., N. Fukushima, T. Abe, Y. Bian, B. Wendelburg, L. Hua, C. J. Yeo, R. Hruban, M. Goggins, and J. R. Eshleman. “LigAmp analysis of KRAS mutations in pancreatic duct juice from patients with pancreatic cancer and chronic pancreatitis.” In Journal of Molecular Diagnostics, 7:684–684. AMER SOC INVESTIGATIVE PATHOLOGY, INC, 2005.
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  - Chandrasekharan, A., C. Shi, P. J. Thuluvath, H. Wistuba, C. A. Karikari, P. Argani, M. G. Goggins, J. R. Eshleman, and A. Maitra. “Ultrasensitive detection of KRAS mutations in bile and serum from patients with biliary cancer using LigAmp technology.” In Modern Pathology, 18:277A-277A. NATURE PUBLISHING GROUP, 2005.
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  - Chandrasekharan, A., C. Shi, P. J. Thuluvath, I. L. Wistuba, C. A. Karikari, P. Argani, M. G. Goggins, J. R. Eshleman, and A. Maitra. “Ultrasensitive detection of KRAS mutations in bile and serum from patients with biliary cancer using LigAmp technology.” In Laboratory Investigation, 85:277A-277A. NATURE PUBLISHING GROUP, 2005.
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