Overview
Christine Payne is the Yoh Family Professor of Mechanical Engineering and Materials Science at Duke University. Her research focuses on understanding how cells interact with nanomaterials. This includes fundamental questions of nanoparticle transport within cells, as well as applied research to understand the pulmonary response to the inhalation of nanoparticles in a manufacturing setting. Her team uses an interdisciplinary approach that includes elements of materials science, chemistry, biophysics, and lab automation. She teaches classes on the quantum mechanics and statistical mechanics of materials including a class on the “Materials Science of Science Fiction.” She earned a S.B. in Chemistry from the University of Chicago (1998) and a Ph.D. in Chemistry from the University of California, Berkeley (2003). Prof. Payne spent 2003-2006 as an NIH NRSA Postdoctoral Fellow at Harvard University. Prof. Payne has received many honors including an NIH Director’s New Innovator Award (2009) and a DARPA Young Faculty Award (2011). She is a Fellow of the Royal Society of Chemistry.
Current Appointments & Affiliations
Recent Publications
Cellular and In Vivo Response to Industrial, Food Grade, and Photocatalytic TiO2 Nanoparticles.
Journal Article J Phys Chem B · September 19, 2024 We encounter titanium dioxide nanoparticles (TiO2 NPs) throughout our daily lives in the form of food coloring, cosmetics, and industrial materials. They are used on a massive industrial scale, with over 1 million metric tons in the global market. For the ... Full text Link to item CiteHouse Dust Mite Proteins Adsorb on Multiwalled Carbon Nanotubes Forming an Allergen Corona That Intensifies Allergic Lung Disease in Mice.
Journal Article ACS nano · September 2024 The increasing use of multiwalled carbon nanotubes (MWCNTs) could increase the risk of allergic lung disease in occupational or consumer settings. We previously reported that MWCNTs exacerbated allergic lung disease in mice induced by extract from house du ... Full text CiteDNA corona on nanoparticles leads to an enhanced immunostimulatory effect with implications for autoimmune diseases.
Journal Article Proceedings of the National Academy of Sciences of the United States of America · March 2024 Autoimmune and inflammatory diseases are highly complex, limiting treatment and the development of new therapies. Recent work has shown that cell-free DNA bound to biological microparticles is linked to systemic lupus erythematosus, a prototypic autoimmune ... Full text CiteRecent Grants
Collaborative Research: Machine Learning for the Protein Corona: An Integrated, Feature-Driven Approach to Predict Nano-Bio Interactions
ResearchPrincipal Investigator · Awarded by National Science Foundation · 2024 - 2027Mechanisms of Nanoparticle Modulation of Allergen-Induced Lung Disease
ResearchPrincipal Investigator · Awarded by North Carolina State University · 2021 - 2026Engineering at the interface: Training interdisciplinary engineers at the PhD level
ResearchPrincipal Investigator · Awarded by Burroughs Wellcome Fund · 2024 - 2025View All Grants