Scholars@Duke
Durga Borkar

Durga Borkar

Associate Professor of Ophthalmology
Ophthalmology, Vitreoretinal Diseases & Surgery

Selected Publications

Real-World Functional Outcomes and Quality of Life in Geographic Atrophy.

Journal Article Ophthalmol Retina · November 19, 2024 Terms related to geographic atrophy progression and ocular comorbidities are well documented in ophthalmology clinical notes, while terms related to vision-related quality of life and functional outcomes are rarely documented. ... Full text Link to item Cite

Systematic analysis of levels of evidence supporting American Academy of Ophthalmology Preferred Practice Pattern guidelines, 2012-2021.

Journal Article BMC Ophthalmol · March 31, 2023 BACKGROUND: Despite the increased emphasis on evidence-based medicine, the current state of evidence behind ophthalmology clinical practice guidelines is unknown. The purpose of this systematic analysis was to understand the levels of evidence (LOE) suppor ... Full text Link to item Cite

Comparison of Modified Posterior Sub-Tenon's vs. Trans-Septal Triamcinolone Injection for Non-infectious Uveitis.

Journal Article Ocul Immunol Inflamm · July 4, 2021 Purpose: To compare the safety and efficacy of trans-septal vs. modified posterior sub-Tenon's (PST) corticosteroid injections for noninfectious uveitis.Methods: Retrospective comparison of periocular triamcinolone injection by modified PST (n = 36) vs. tr ... Full text Link to item Cite

Effect of ICD-9 to ICD-10 Transition on Accuracy of Codes for Stage of Diabetic Retinopathy and Related Complications: Results from the CODER Study.

Journal Article Ophthalmol Retina · April 2021 PURPOSE: When the International Classification of Diseases 9th Revision (ICD-9) transitioned to the International Classification of Diseases 10th Revision (ICD-10), there was a marked increase in the complexity of International Classification of Diseases ( ... Full text Link to item Cite

Healthcare disparities contribute to missed follow-up visits after cataract surgery in the USA: results from the perioperative care for intraocular lens study.

Journal Article BMJ Open · March 17, 2021 OBJECTIVE: To identify factors that contribute to missed cataract surgery follow-up visits, with an emphasis on socioeconomic and demographic factors. METHODS: In this retrospective cohort study, patients who underwent cataract extraction by phacoemulsific ... Full text Link to item Cite

Incidence of Management Changes at the Postoperative Day One Visit After Pars Plana Vitrectomy for Retinal Detachment.

Journal Article Am J Ophthalmol · February 2021 PURPOSE: To evaluate the incidence of unexpected management changes on the first day after pars plana vitrectomy (PPV) for retinal detachment repair. DESIGN: Retrospective cohort study. METHODS: The medical and billing records of a large academic private p ... Full text Link to item Cite

Quantifying the educational benefit of additional cataract surgery cases in ophthalmology residency.

Journal Article J Cataract Refract Surg · November 2020 PURPOSE: To quantify the resident learning curve for cataract surgery using operative time as an indicator of surgical competency, to identify the case threshold at which marginal additional educational benefit became equivocal, and to characterize heterog ... Full text Link to item Cite

Outcomes of Eyes Lost to Follow-up with Neovascular Age-Related Macular Degeneration Receiving Intravitreal Anti-Vascular Endothelial Growth Factor.

Journal Article Ophthalmol Retina · February 2020 PURPOSE: To determine outcomes of eyes with neovascular age-related macular degeneration (nAMD) receiving intravitreal anti-vascular endothelial growth factor (VEGF) injections who return after a period of being lost to follow-up (LTFU). DESIGN: Retrospect ... Full text Link to item Cite

OCULAR HYPERTENSION AFTER INTRAVITREAL INJECTION OF 2-MG TRIAMCINOLONE.

Journal Article Retina · January 2020 PURPOSE: To report the incidence and course of ocular hypertension after intravitreal injection of 2-mg triamcinolone acetonide (IVT). METHODS: In a retrospective, consecutive series, all patients receiving 2-mg IVT at a single institution between March 1, ... Full text Link to item Cite

Clinical factors affecting operating room utilization in cataract surgery: Results from the PCIOL study.

Journal Article J Cataract Refract Surg · January 2020 PURPOSE: To identify preoperative clinical characteristics affecting cataract surgery operative time. SETTING: Academic center. DESIGN: Large-scale retrospective cohort study. METHODS: All cases of cataract extraction by phacoemulsification and intraocular ... Full text Link to item Cite

Reply.

Journal Article Am J Ophthalmol · December 2019 Full text Link to item Cite

Rhegmatogenous Retinal Detachment after Intravitreal Injection of Anti-Vascular Endothelial Growth Factor.

Journal Article Ophthalmology · October 2019 PURPOSE: To report the rate, risk factors, and outcomes of rhegmatogenous retinal detachment (RRD) after intravitreal injection of anti-vascular endothelial growth factor medications. DESIGN: Single-center, retrospective, consecutive review. PARTICIPANTS: ... Full text Link to item Cite

Endophthalmitis Rates and Clinical Outcomes Following Penetrating and Endothelial Keratoplasty.

Journal Article Am J Ophthalmol · September 2019 PURPOSE: To evaluate endophthalmitis rates after penetrating keratoplasty (PK) and endothelial keratoplasty (EK) and to compare clinical outcomes. DESIGN: Retrospective cohort study. METHODS: The medical and billing records of several large academic privat ... Full text Link to item Cite

Use of Telehealth Screening to Detect Diabetic Retinopathy and Other Ocular Findings in Primary Care Settings.

Journal Article Telemed J E Health · September 2019 Purpose: To determine the incidence of diabetic retinopathy (DR) and other ocular findings in previously diagnosed diabetes using telehealth retinal screening with nonmydriatic fundus photography (nFP) in primary care physicians' offices.Methods: A retrosp ... Full text Link to item Cite

Refractive Outcomes after Pars Plana Vitrectomy and Scleral Fixated Intraocular Lens with Gore-Tex Suture.

Journal Article Ophthalmol Retina · July 2019 PURPOSE: To evaluate refractive outcomes after combined pars plana vitrectomy (PPV) and scleral fixation of an intraocular lens (IOL) using Gore-Tex suture. DESIGN: Retrospective cohort study. PARTICIPANTS: Fifty-five eyes from 53 patients who underwent PP ... Full text Link to item Cite

The Impact of Prefilled Syringes on Endophthalmitis Following Intravitreal Injection of Ranibizumab.

Journal Article Am J Ophthalmol · March 2019 PURPOSE: To compare the rates of infectious endophthalmitis following intravitreal injection of ranibizumab using prefilled syringes vs conventional preparation. DESIGN: Multicenter retrospective cohort study. METHODS: All eyes receiving intravitreal injec ... Full text Link to item Cite

Incidence of Management Changes at the Postoperative Week 1 Visit after Cataract Surgery: Results from the Perioperative Care for IntraOcular Lens Study.

Journal Article Am J Ophthalmol · March 2019 PURPOSE: To ascertain the incidence of unexpected management changes at the postoperative week 1 visit in asymptomatic patients who have had an uncomplicated cataract surgery and a routine postoperative day 1 examination. DESIGN: Retrospective observationa ... Full text Link to item Cite

Outcomes of Eyes Lost to Follow-up with Proliferative Diabetic Retinopathy That Received Panretinal Photocoagulation versus Intravitreal Anti-Vascular Endothelial Growth Factor.

Journal Article Ophthalmology · March 2019 PURPOSE: To compare anatomic and functional outcomes in eyes with proliferative diabetic retinopathy (PDR) that were lost to follow-up (LTFU) for more than 6 months after treatment with either intravitreal injection (IVI) of anti-vascular endothelial growt ... Full text Link to item Cite

Reply.

Journal Article J Cataract Refract Surg · January 2019 Full text Link to item Cite

Optimization of cataract surgery follow-up: A standard set of questions can predict unexpected management changes at postoperative week one.

Journal Article PLoS One · 2019 PURPOSE: There is limited evidence to inform the optimal follow-up schedule after cataract surgery. This study aims to determine whether a standardized question set can predict unexpected management changes (UMCs) at the postoperative week one (POW1) timep ... Full text Link to item Cite

Reply.

Journal Article Am J Ophthalmol · December 2018 Full text Link to item Cite

Outcomes in resident-performed cataract surgeries with iris challenges: Results from the Perioperative Care for Intraocular Lens study.

Journal Article J Cataract Refract Surg · December 2018 PURPOSE: To assess the outcomes of resident-performed cataract surgeries with iris challenges and to compare these outcomes with similar surgeries performed by attending surgeons. SETTING: Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston ... Full text Link to item Cite

Endophthalmitis Rates after Bilateral Same-Day Intravitreal Anti-Vascular Endothelial Growth Factor Injections.

Journal Article Am J Ophthalmol · October 2018 PURPOSE: To evaluate practice patterns for bilateral same-day intravitreal anti-vascular endothelial growth factor (VEGF) injections and determine the rate of unilateral and bilateral postinjection endophthalmitis after bilateral same-day intravitreal anti ... Full text Link to item Cite

Transition time

Journal Article Retina Today · July 1, 2018 Cite

Manual red cell exchange transfusion to avert sickle cell related complications.

Journal Article Asian J Transfus Sci · 2018 Sickle cell-beta thalassemia is a double heterozygous state. Red cell exchange (RCE) transfusion reduces the concentration of sickle cells without increasing the hematocrit or whole-blood viscosity. It can be performed manually or by erythrocytapheresis. R ... Full text Link to item Cite

Buccal Mucosa Exfoliative Cell Prussian Blue Stain Co-Relates with Iron Overload in β-Thalassemia Major Patients.

Journal Article Indian J Hematol Blood Transfus · December 2017 Thalassemics require regular blood transfusion therapy leading to iron overload in the body tissues, which is a major cause of morbidity and mortality in these patients. We hereby attempted to measure this iron overload by means of exfoliative cytology, a ... Full text Link to item Cite

Descemet Membrane Endothelial Keratoplasty After Failed Descemet Stripping Without Endothelial Keratoplasty.

Journal Article Cornea · July 2017 PURPOSE: To describe the clinical course, surgical experience, and postoperative outcomes of 3 patients with Fuchs endothelial dystrophy who underwent Descemet membrane endothelial keratoplasty (DMEK) after failed Descemet stripping without endothelial ker ... Full text Link to item Cite

Association Between Thyroid Disease and Uveitis: Results From the Pacific Ocular Inflammation Study.

Journal Article JAMA Ophthalmol · June 1, 2017 IMPORTANCE: Common pathophysiological mechanisms may be responsible for immune dysregulation in both thyroid disease and uveitis. Studies investigating a possible association are limited. OBJECTIVE: To determine the association between thyroid disease and ... Full text Link to item Cite

Treatment of Fuchs Endothelial Dystrophy by Descemet Stripping Without Endothelial Keratoplasty.

Conference Cornea · October 2016 PURPOSE: To evaluate the effect of deliberate removal of the central Descemet membrane on endothelial function and morphology in patients with Fuchs endothelial dystrophy (FED) and cataract undergoing phacoemulsification. METHODS: In this retrospective cas ... Full text Link to item Cite

Assessment of the Accuracy of Using ICD-9 Codes to Identify Uveitis, Herpes Zoster Ophthalmicus, Scleritis, and Episcleritis.

Conference JAMA Ophthalmol · September 1, 2016 IMPORTANCE: With the increased use of data from electronic medical records for research, it is important to validate International Classification of Diseases, Ninth Revision (ICD-9) codes for their respective diagnoses. OBJECTIVE: To assess the accuracy of ... Full text Link to item Cite

Intraocular Teratoid Medulloepithelioma Presenting With a Completely Rhabdomyosarcomatous Distant Metastasis.

Journal Article JAMA Ophthalmol · August 1, 2016 IMPORTANCE: Medulloepithelioma is the second most common primary neuroepithelial tumor of the eye. The full range of its morphologic expressions and appearances in metastases have not been fully explored. OBSERVATIONS: A patient in her 50s with glaucoma fo ... Full text Link to item Cite

Have your data and query it too: From key-value caching to big data management

Conference Proceedings of the ACM SIGMOD International Conference on Management of Data · June 26, 2016 Couchbase Server is a rethinking of the database given the current set of realities. Memory today is much cheaper than disks were when traditional databases were designed back in the 1970's, and networks are much faster and much more reliable than ever bef ... Full text Cite

Pink hypopyon in a patient with Serratia marcescens corneal ulceration

Journal Article Journal of Ophthalmic Inflammation and Infection · December 1, 2015 A 65-year-old woman presented to the emergency ward at the Massachusetts Eye and Ear Infirmary with 2 days of redness, irritation, photophobia, and diminished vision in her left eye. She was found to have a large central corneal ulcer with a small hypopyon ... Full text Cite

Association between Smoking and Uveitis: Results from the Pacific Ocular Inflammation Study.

Journal Article Ophthalmology · June 2015 PURPOSE: To assess whether cigarette smoking is associated with the development of uveitis in a population-based setting. DESIGN: Retrospective, population-based, case-control study. PARTICIPANTS: Patients aged ≥ 18 years who were seen at a Kaiser Permanen ... Full text Link to item Cite

Association between statin use and uveitis: results from the Pacific Ocular Inflammation study.

Journal Article Am J Ophthalmol · April 2015 PURPOSE: To assess whether there is a protective association between statin use and uveitis diagnosis. DESIGN: Retrospective, population-based case-control study. METHODS: Medical records of all patients in the Kaiser Permanente Hawaii health plan between ... Full text Link to item Cite

Use of Screening and Surveillance Colonoscopy in a Community Teaching Hospital

Conference American Journal of Gastroenterology · October 2014 Full text Cite

Cytotoxic clinical isolates of Pseudomonas aeruginosa identified during the Steroids for Corneal Ulcers Trial show elevated resistance to fluoroquinolones.

Journal Article BMC Ophthalmol · April 24, 2014 BACKGROUND: To determine the relationship between type three secretion genotype and fluoroquinolone resistance for P. aeruginosa strains isolated from microbial keratitis during the Steroids for Corneal Ulcers Trial (SCUT) and for two laboratory strains, P ... Full text Link to item Cite

Evaluation of conjunctival scarring in graft-versushost disease

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · April 1, 2014 Link to item Cite

Association between Statin Use and Uveitis: Results from the Pacific Ocular Inflammation Study

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · April 1, 2014 Link to item Cite

Association between atopy and herpetic eye disease: results from the pacific ocular inflammation study.

Journal Article JAMA Ophthalmol · March 2014 IMPORTANCE: Immune dysregulation in patients with atopy has been hypothesized to increase susceptibility to viral infections. Herpetic eye disease (due to herpes simplex and herpes zoster) is a significant cause of visual impairment, and data on an associa ... Full text Link to item Cite

Acanthamoeba, fungal, and bacterial keratitis: A comparison of risk factors and clinical features

Journal Article American Journal of Ophthalmology · January 1, 2014 Purpose To determine risk factors and clinical signs that may differentiate between bacterial, fungal, and acanthamoeba keratitis among patients presenting with presumed infectious keratitis. Design Hospital-based cross-sectional study. Methods We examined ... Full text Cite

Media coverage of medical journals: do the best articles make the news?

Journal Article PLoS One · 2014 BACKGROUND: News coverage of medical research is followed closely by many Americans and affects the practice of medicine and influence of scientific research. Prior work has examined the quality of media coverage, but no investigation has characterized the ... Full text Link to item Cite

Incidence and prevalence of uveitis: results from the Pacific Ocular Inflammation Study.

Journal Article JAMA Ophthalmol · November 2013 IMPORTANCE: Uveitis is responsible for a significant proportion of legal blindness in the United States. Currently, there are few population-based reports characterizing the epidemiology of uveitis. OBJECTIVE: To ascertain the incidence and prevalence of u ... Full text Link to item Cite

Incidence of scleritis and episcleritis: results from the Pacific Ocular Inflammation Study.

Journal Article Am J Ophthalmol · October 2013 PURPOSE: To ascertain the incidence of scleritis and episcleritis in a Hawaiian population and describe variations by age, sex, and race. DESIGN: Retrospective, population-based cohort study. METHODS: All electronic medical records for enrollees in Kaiser ... Full text Link to item Cite

A decade of reversal: an analysis of 146 contradicted medical practices.

Journal Article Mayo Clin Proc · August 2013 OBJECTIVE: To identify medical practices that offer no net benefits. METHODS: We reviewed all original articles published in 10 years (2001-2010) in one high-impact journal. Articles were classified on the basis of whether they addressed a medical practice ... Full text Link to item Cite

Emerging moxifloxacin resistance in Pseudomonas aeruginosa keratitis isolates in South India.

Journal Article Ophthalmic Epidemiol · June 2013 PURPOSE: To describe temporal trends in Pseudomonas aeruginosa resistance to moxifloxacin in keratitis isolates from South India. METHODS: The Steroids for Corneal Ulcers Trial (SCUT) was a randomized, double-masked, placebo-controlled trial assessing outc ... Full text Link to item Cite

Spectrum of ocular toxicities from epidermal growth factor receptor inhibitors and their intermediate-term follow-up: a five-year review.

Journal Article Support Care Cancer · April 2013 PURPOSE: Epidermal growth factor receptor (EGFR) inhibitors and kinases are commonly used in the treatment regimen of various solid tumors including non-small cell lung, colorectal, head and neck, breast, and pancreatic cancers. The aim of this study is to ... Full text Link to item Cite

Incidence of herpes zoster ophthalmicus: results from the Pacific Ocular Inflammation Study.

Journal Article Ophthalmology · March 2013 PURPOSE: To provide a population-based estimate of the incidence of herpes zoster ophthalmicus (HZO) with comparisons across racial, sex, and age groups, as well as to estimate the frequency of postherpetic neuralgia (PHN). DESIGN: Retrospective, populatio ... Full text Link to item Cite

Association between cytotoxic and invasive Pseudomonas aeruginosa and clinical outcomes in bacterial keratitis.

Journal Article JAMA Ophthalmol · February 2013 OBJECTIVES: To determine whether cytotoxic and invasive Pseudomonas aeruginosa strains differentially influence clinical presentation, outcomes, or therapeutic response in bacterial keratitis. METHODS: Pseudomonas aeruginosa isolates from the National Eye ... Full text Link to item Cite

Analysis of Unsymmetrical fault using Symmetrical component for Improvement of Overcurrent Protection Scheme

Conference 2013 INTERNATIONAL CONFERENCE ON COMPUTER COMMUNICATION AND INFORMATICS · January 1, 2013 Link to item Cite

Design and synthesis of p-hydroxybenzohydrazide derivatives for their antimycobacterial activity

Journal Article Journal of the Korean Chemical Society · April 20, 2012 The main mycobacterial infection in human is tuberculosis caused by Mycobacterium tuberculosis. Tuberculosis is the leading infectious cause of death in the world. Therefore there is continuing and compelling need for new and improved treatment for tubercu ... Full text Cite

Unilateral multicystic dysplasia in an ectopic kidney.

Journal Article Indian J Pathol Microbiol · 2011 Full text Link to item Cite

Synthesis and biological evaluation of schiff bases of cinchophen as antimicrobial agents

Journal Article International Journal of ChemTech Research · December 1, 2009 Cinchophen (I) was synthesized from pyruvic acid, aniline and benzaldehyde by Doebner synthesis. Cinchophen acid chloride (II) was synthesised from cinchophen and oxalyl chloride by acylation reaction. The 2-phenylquinoline-4- carboxylic acid amide (III) w ... Cite

Simultaneous estimation of paracetamol and promethazine hydrochloride in pharmaceutical formulations by a RP-HPLC method

Journal Article International Journal of ChemTech Research · December 1, 2009 A rapid and sensitive high performance liquid chromatography method for determination of paracetamol and promethazine hydrochloride has been developed. The chromatography system used a reversed phase C18 column (HiQ Sil C18, 5μ, 250 mm x 4.6 mm). The sampl ... Cite

Longstanding lupus vulgaris with basal cell carcinoma.

Journal Article Indian J Pathol Microbiol · 2009 Full text Link to item Cite

Multicenter clinical trials on a novel polyherbal formulation in allergic rhinitis.

Journal Article Int J Clin Pharmacol Res · 2004 Allergic rhinitis is the most frequently occurring immunological disorder. It affects men, women and children and represents significant cost in terms of suffering and loss of productivity. Allergy is termed as an excessive reaction to an environmental all ... Link to item Cite

Techniques of selective cannulation and sphincterotomy.

Conference Endoscopy · August 2003 Selective access into the desired duct followed by incision of the sphincter, i. e. sphincterotomy, forms the cornerstone of any endoscopic intervention within the pancreaticobiliary system. The apprehensive beginner's performance and hesitance is aggravat ... Full text Link to item Cite

Capsule endoscopy diagnosis of ileal anglodysplasia.

Journal Article Indian J Gastroenterol · 2003 A 59-year-old lady presented with iron-deficiency anemia secondary to occult gastrointestinal bleeding, which had needed multiple transfusions over five years. Standard investigations for gastrointestinal bleeding were normal. Capsule endoscopy, a new tech ... Link to item Cite

Effects of intranasal administration of norethisterone on folliculogenesis, cervical mucus, vaginal cytology, endometrial morphology and reproductive-endocrine profile in women.

Journal Article Contraception · September 1991 The effects of intranasal administration of norethisterone (NET) on menstrual cycle length, folliculogenesis, serum levels of estradiol, FSH, LH and progesterone, vaginal cytology, cervical mucus and endometrial morphology were studied in 8 volunteers (age ... Full text Link to item Cite

Electrostatic charge measurements on initiators and explosive powders

Journal Article Propellants, Explosives, Pyrotechnics · January 1, 1983 New mechanical handling system for simulating the handling of explosive powders in the explosives factories have been designed, developed and successfully used for measurements of electrostatic charges under actual working conditions. The results of some o ... Full text Cite

Chronic otitis media.

Journal Article Q Med Rev · January 1980 Link to item Cite

Glossopharyngeal neuralgia

Journal Article Indian Journal of Otolaryngology · March 1, 1978 Idiopathic glossopharyngeal neuralgia is rare. The diagnosis is not difficult and treatment is only surgical. The cervical approach is the best for the condition. We have had no recurrences so far during 1 to 2 years followup. Excision of tonsils and/or el ... Full text Cite