Scholars@Duke
Geoffroy C Sisk

Selected Publications

Cultural Influences on the Receipt of Breast Reconstruction: A Scoping Review.

Journal Article Plast Reconstr Surg · March 1, 2025 BACKGROUND: Postmastectomy breast reconstruction can provide breast cancer patients with lasting psychosocial, functional, and body image benefits. Although sociodemographic factors affecting the receipt of breast reconstruction have been well studied, the ... Full text Link to item Cite

A Multi-institutional Analysis of a Textbook Outcome Among Patients Undergoing Microvascular Breast Reconstruction.

Journal Article Ann Plast Surg · June 1, 2024 BACKGROUND: Individual outcomes may not accurately reflect the quality of perioperative care. Textbook outcomes (TOs) are composite metrics that provide a comprehensive evaluation of hospital performance and surgical quality. This study aimed to investigat ... Full text Link to item Cite

One-Stage Deep Inferior Epigastric Perforator Flap Salvage of Infected Tissue Expanders.

Journal Article Ann Plast Surg · June 1, 2024 BACKGROUND: Tissue expander-based breast reconstruction is associated with high rates of infectious complications, often leading to tissue expander explants and delays in receipt of definitive breast reconstruction and adjuvant therapy. In this study, we d ... Full text Link to item Cite

Efficacy of Prophylactic Postoperative Antibiotics in Tissue Expander-Based Breast Reconstruction: A Propensity Score-Matched Analysis.

Journal Article Plast Reconstr Surg · March 1, 2024 BACKGROUND: Conflicting evidence exists regarding the utility of prophylactic postoperative antibiotics in tissue expander (TE)-based breast reconstruction. This study evaluated the risk of surgical-site infection between patients receiving 24 hours of per ... Full text Link to item Cite

Air or Saline? A Propensity Score-Matched Analysis on the Effect of Tissue Expander Fill on Complications in Immediate Breast Reconstruction.

Journal Article Ann Surg Oncol · October 2023 BACKGROUND: Tissue expander fill medium and volume have implications for the pressure exerted on mastectomy skin flaps. This study evaluated the influence of initial fill medium (air vs. saline) on complications in immediate breast reconstruction within a ... Full text Link to item Cite

Textbook outcomes in DIEP flap breast reconstruction: a Delphi study to establish consensus.

Journal Article Breast Cancer Res Treat · February 2023 PURPOSE: Composite measures, like textbook outcomes, may be superior to individual metrics when assessing hospital performance and quality of care. This study utilized a Delphi process to define a textbook outcome in DIEP flap breast reconstruction. METHOD ... Full text Link to item Cite

Defining the Value of Breast Reconstruction Surgeons: Quantifying Clinical Encounter and Operative Volume at an Academic Center.

Journal Article Plast Reconstr Surg Glob Open · December 2022 UNLABELLED: Despite growing rates of postmastectomy breast reconstruction, the time contribution of breast reconstruction surgeons in comprehensive breast cancer care is often poorly accounted for by hospital and healthcare systems. This study models encou ... Full text Link to item Cite

Microvascular Breast Reconstruction in the Era of Value-Based Care: Use of a Cosurgeon Is Associated with Reduced Costs, Improved Outcomes, and Added Value.

Journal Article Plast Reconstr Surg · February 1, 2022 BACKGROUND: Reducing complications while controlling costs is a central tenet of value-based health care. Bilateral microvascular breast reconstruction is a long operation with a relatively high complication rate. Using a two-surgeon team has been shown to ... Full text Link to item Cite

Advances in Autologous Breast Reconstruction

Journal Article Current Surgery Reports · January 1, 2021 Autologous breast reconstruction (ABR) in patients undergoing mastectomy is now routinely performed, and associated with high rates of success and minimal donor site morbidity. Compared to alloplastic techniques, advantages of autologous approaches include ... Full text Cite

Lymphovenous anastomosis using the venous coupler.

Journal Article J Plast Reconstr Aesthet Surg · May 2020 Full text Link to item Cite

Reconstruction of extremity long bone defects with vascularized fibula bone grafts

Journal Article Plastic and Aesthetic Research · January 1, 2019 Aim: Composite tissue defects encompassing bone and/or isolated bony defects can pose a surgical challenge; however, their reconstruction is critical for successful functional limb salvage. These cases become increasingly problematic as secondary defects, ... Full text Cite

Abdominal Wall Reconstruction: An Integrated Approach

Journal Article Seminars in Plastic Surgery · August 1, 2018 Abdominal wall reconstruction has undergone substantial evolution over the last few decades. The optimal method of repair should be tailored to each patient's unique condition; however, a general approach that integrates four major factors can be applied a ... Full text Cite

A Mobile Extracorporeal Extremity Salvage System for Replantation and Transplantation.

Journal Article Ann Plast Surg · March 2016 BACKGROUND: Traumatic amputation is the second leading cause of limb loss in the United States. The preferred treatment is salvage and replantation of the amputated limb, whenever possible, and allotransplantation is a novel procedure whereby healthy limbs ... Full text Link to item Cite

Functional Outcomes after Bilateral Hand Transplantation: A 3.5-Year Comprehensive Follow-Up.

Journal Article Plast Reconstr Surg · January 2016 BACKGROUND: Since the first successful hand transplantation in 1998, 72 patients have been operated on for unilateral/bilateral hand transplantation across 13 countries. There have been multiple studies evaluating the outcomes of hand transplantation; howe ... Full text Link to item Cite

Initial experience of dual maintenance immunosuppression with steroid withdrawal in vascular composite tissue allotransplantation.

Journal Article Am J Transplant · May 2015 Current immunosuppression in VCA is largely based on the experience in solid organ transplantation. It remains unclear if steroids can be reduced safely in VCA recipients. We report on five VCA recipients who were weaned off maintenance steroids after a me ... Full text Link to item Cite

Psychosocial outcomes after bilateral hand transplantation

Journal Article Plastic and Reconstructive Surgery - Global Open · January 1, 2015 Background: Since the first successful hand transplantation in 1998, there have been multiple reports about surgical technique, transplant survival, and immunosuppression. However, very limited published data exist on psychosocial outcomes following hand t ... Full text Cite

Vascular communications between donor and recipient tissues after successful full face transplantation.

Journal Article Am J Transplant · March 2014 The vascular reorganization after facial transplantation has important implications on future surgical planning. The purpose of this study was to evaluate blood flow (BF) after full face transplantation using wide area-detector computed tomography (CT) tec ... Full text Link to item Cite

Moist dressing coverage supports proliferation and migration of transplanted skin micrografts in full-thickness porcine wounds.

Journal Article Burns · March 2014 Transplantation of skin micrografts in a 1:100 ratio regenerate the epidermis of full-thickness wounds in pigs within 14 days in a wet environment. The aim of the current study was to combine micrografts and commercially available moist dressings. We hypot ... Full text Link to item Cite

Rehabilitation following hand transplantation

Journal Article Hand · January 1, 2014 Background: Hand allotransplantation can restore motor, sensory and cosmetic functions to upper extremity amputees. Over 70 hand transplant operations have been performed worldwide, but there is little published regarding post-hand transplant rehabilitatio ... Full text Cite

Evolution of ethical debate on face transplantation.

Journal Article Plast Reconstr Surg · December 2013 BACKGROUND: Face transplantation can provide improved quality of life to severely disfigured individuals. The unique challenges of face transplantation prompted much ethical discussion even before the first clinical case. Many deemed it unethical, because ... Full text Link to item Cite

Facial allotransplantation: a 3-year follow-up report.

Journal Article J Plast Reconstr Aesthet Surg · November 2013 INTRODUCTION: Long term follow-up of face transplant patients is fundamental to our understanding of risks and benefits of this procedure. Worldwide experience has shown that function improves gradually over time. METHODS: In April of 2009, a multidiscipli ... Full text Link to item Cite

Current principles of facial allotransplantation: the Brigham and Women's Hospital Experience.

Journal Article Plast Reconstr Surg · May 2013 BACKGROUND: Facial allotransplantation is a revolutionary operation that has at last introduced the possibility of nearly normal facial restoration to patients afflicted by the most severe cases of facial disfigurement. METHODS: The facial transplantation ... Full text Link to item Cite

Vascularized composite tissue allotransplantation--state of the art.

Journal Article Clin Transplant · 2013 Vascularized composite tissue allotransplantation is a viable treatment option for injuries and defects that involve multiple layers of functional tissue. In the past 15 yr, more than 150 vascularized composite allotransplantation (VCA) surgeries have been ... Full text Link to item Cite

A bio-inspired swellable microneedle adhesive for mechanical interlocking with tissue.

Journal Article Nat Commun · 2013 Achieving significant adhesion to soft tissues while minimizing tissue damage poses a considerable clinical challenge. Chemical-based adhesives require tissue-specific reactive chemistry, typically inducing a significant inflammatory response. Staples are ... Full text Link to item Cite

Vascularized composite allotransplantation and tissue engineering.

Journal Article J Craniofac Surg · January 2013 For many living with the devastating aftermath of disfiguring facial injuries, extremity amputations, and other composite tissues defects, conventional reconstruction offers limited relief. Full restoration of the face or extremities with anatomic equivale ... Full text Link to item Cite

Novel surgical technique for full face transplantation.

Journal Article Plast Reconstr Surg · September 2012 BACKGROUND: Full face transplantation raises a new set of ethical concerns and technical difficulties when compared with partial face transplantation. Previously, it was thought that full face allografts must include bilateral superficial temporal and faci ... Full text Link to item Cite

Synchronous carotid body and thoracic paraganglioma associated with a germline SDHC mutation.

Journal Article J Vasc Surg · March 2011 Paraganglionic tumors are rare. A germline mutation responsible for a familial pattern of paragangliomas (PGLs) has been identified on the genes encoding for the subunits of succinate dehydrogenase (SDH). Manifestations of those with a succinate dehydrogen ... Full text Link to item Cite

Diapause in the pea aphid (Acyrthosiphon pisum) is a slowing but not a cessation of development.

Journal Article BMC Dev Biol · August 8, 2003 BACKGROUND: Many insects undergo a period of arrested development, called diapause, to avoid seasonally recurring adverse conditions. Whilst the phenology and endocrinology of insect diapause have been well studied, there has been comparatively little rese ... Full text Link to item Cite

A comparison of parthenogenetic and sexual embryogenesis of the pea aphid Acyrthosiphon pisum (Hemiptera: Aphidoidea).

Journal Article J Exp Zool B Mol Dev Evol · February 15, 2003 Aphids exhibit divergent modes of embryogenesis during the sexual and asexual phases of the life cycle. To explore how a single genome can give rise to these alternative developmental modes, we have initiated embryological studies of the pea aphid, Acyrtho ... Full text Link to item Cite

A comparison of parthenogenetic and sexual embryogenesis of the pea aphid Acyrthosiphon pisum (Hemiptera:Aphidoidea)

Journal Article JOURNAL OF EXPERIMENTAL ZOOLOGY PART B-MOLECULAR AND DEVELOPMENTAL EVOLUTION · 2003 Full text Cite