Kyle C. Strickland | Scholars@Duke

Kyle C. Strickland
Assistant Professor of Pathology

Dr. Strickland specializes in cytopathology and women's and perinatal surgical pathology. His areas of interest include epithelial and mesenchymal gynecologic neoplasia and fine needle aspiration cytology.

Current Appointments & Affiliations

Assistant Professor of Pathology, Pathology, Clinical Science Departments 2017
Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 2018

Contact Information

40 Duke Medicine Circle, Purple Zone, Rm 3418, Durham, NC 27710
Box 3712, Durham, NC 27710
kyle.strickland@duke.edu (919) 684-3205

Background
Education, Training, & Certifications
- Fellow, Women's and Perinatal Pathology, Harvard Medical School, Brigham and Women's Hospital 2016 - 2017
- Fellow, Cytopathology, Harvard Medical School, Brigham and Women's Hospital 2015 - 2016
- Resident, Anatomic Pathology, Harvard Medical School, Brigham and Women's Hospital 2013 - 2015
- MD./PhD., Medical University of South Carolina School of Medicine 2013
- B.A., College of Charleston 2005
- B.S., College of Charleston 2005
Research
Selected Grants
- Immune modulation of CaMKK2 in the ovarian tumor microenvironment awarded by American Association of Obstetricians and Gynecologists Foundation 2019 - 2020
Publications & Artistic Works
Selected Publications
- Conference Papers
  - Brouwer, J, Strickland, KC, Schmelkin, C, Kolin, D, Hecht, J, Nucci, M, Xian, W, and Crum, C. "Evidence for a Unique Endometrioid Carcinogenic Sequence in the Fallopian Tube Associated with a type II (Endometrioid) Secretory Cell Outgrowth (SCOUT)." 107th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology (USCAP). Vancouver, CANADA. March 17, 2018 - March 23, 2018.: NATURE PUBLISHING GROUP, March 1, 2018. Link to Item
  - Strickland, KC, Campbell, F, Miron, A, Howitt, BE, and Crum, C. "Detection of Tumor-Specific TP53 Signatures from Archival Endometrial Biopsies Obtained Prior to the Diagnosis of High-Grade Serous Carcinoma." 107th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology (USCAP). Vancouver, CANADA. March 17, 2018 - March 23, 2018.: NATURE PUBLISHING GROUP, March 1, 2018. Link to Item
- Journal Articles
  - Davis, M, Strickland, K, Easter, SR, Worley, M, Feltmate, C, Muto, M, Horowitz, N, Berkowitz, R, and Feldman, S. "The impact of health insurance status on the stage of cervical cancer diagnosis at a tertiary care center in Massachusetts." Gynecologic Oncology 150, no. 1 (July 2018): 67-72. Full Text
  - Meserve, EE, Strickland, KC, Miron, A, Soong, TR, Campbell, F, Howitt, BE, and Crum, CP. "Evidence of a Monoclonal Origin for Bilateral Serous Tubal Intraepithelial Neoplasia." International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists (June 12, 2018). Full Text
  - Ditzel, HM, Strickland, KC, Meserve, EE, Stover, E, Konstantinopoulos, PA, Matulonis, UA, Muto, MG, Liu, JF, Feltmate, C, Horowitz, N, Berkowitz, RS, Gupta, M, Hecht, JL, Lin, DI, Jochumsen, KM, Welch, WR, Hirsch, MS, Quade, BJ, Lee, KR, Crum, CP, Mutter, GL, Nucci, MR, and Howitt, BE. "Assessment of a Chemotherapy Response Score (CRS) System for Tubo-Ovarian High-Grade Serous Carcinoma (HGSC)." International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists (May 10, 2018). Full Text
  - Angell, TE, Vyas, CM, Barletta, JA, Cibas, ES, Cho, NL, Doherty, GM, Gawande, AA, Howitt, BE, Krane, JF, Marqusee, E, Strickland, KC, Alexander, EK, Moore, FD, and Nehs, MA. "Reasons Associated with Total Thyroidectomy as Initial Surgical Management of an Indeterminate Thyroid Nodule (Accepted)." Annals of Surgical Oncology (March 8, 2018): 1-8. Full Text
  - Strickland, KC, Eszlinger, M, Paschke, R, Angell, TE, Alexander, EK, Marqusee, E, Nehs, MA, Jo, VY, Lowe, A, Vivero, M, Hollowell, M, Qian, X, Wieczorek, T, French, CA, Teot, LA, Cibas, ES, Lindeman, NI, Krane, JF, and Barletta, JA. "Molecular Testing of Nodules with a Suspicious or Malignant Cytologic Diagnosis in the Setting of Non-Invasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features (NIFTP)." Endocrine Pathology 29, no. 1 (March 2018): 68-74. Full Text
  - Strickland, KC, Howitt, BE, Barletta, JA, Cibas, ES, and Krane, JF. "Suggesting the cytologic diagnosis of noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP): A retrospective analysis of atypical and suspicious nodules." Cancer Cytopathology 126, no. 2 (February 2018): 86-93. Full Text Open Access Copy
  - Meserve, EEK, Mirkovic, J, Conner, JR, Yang, E, Muto, MG, Horowitz, N, Strickland, KC, Howitt, BE, and Crum, CP. "Frequency of "incidental" serous tubal intraepithelial carcinoma (STIC) in women without a history of or genetic risk factor for high-grade serous carcinoma: A six-year study." Gynecologic Oncology 146, no. 1 (July 2017): 69-73. Full Text Open Access Copy
  - Sullivan, MC, Graham, PH, Alexander, EK, Ruan, DT, Nehs, MA, Gawande, AA, Moore, FD, Howitt, BE, Strickland, KC, Krane, JF, Barletta, JA, and Cho, NL. "Prevalence of Contralateral Tumors in Patients with Follicular Variant of Papillary Thyroid Cancer." Journal of the American College of Surgeons 224, no. 6 (June 2017): 1021-1027. Full Text Open Access Copy
  - Wong, KS, Strickland, KC, Angell, TE, Nehs, MA, Alexander, EK, Cibas, ES, Krane, JF, Howitt, BE, and Barletta, JA. "The Flip Side of NIFTP: an Increase in Rates of Unfavorable Histologic Parameters in the Remainder of Papillary Thyroid Carcinomas." Endocrine pathology 28, no. 2 (June 2017): 171-176. Full Text Open Access Copy
  - Baca, SC, Wong, KS, Strickland, KC, Heller, HT, Kim, MI, Barletta, JA, Cibas, ES, Krane, JF, Marqusee, E, and Angell, TE. "Qualifiers of atypia in the cytologic diagnosis of thyroid nodules are associated with different Afirma gene expression classifier results and clinical outcomes." Cancer Cytopathology 125, no. 5 (May 2017): 313-322. Full Text Open Access Copy
  - Howitt, BE, Strickland, KC, Sholl, LM, Rodig, S, Ritterhouse, LL, Chowdhury, D, D'Andrea, AD, Matulonis, UA, and Konstantinopoulos, PA. "Clear cell ovarian cancers with microsatellite instability: A unique subset of ovarian cancers with increased tumor-infiltrating lymphocytes and PD-1/PD-L1 expression." Oncoimmunology 6, no. 2 (January 6, 2017): e1277308-null. Full Text Open Access Copy
  - Strickland, KC, Vivero, M, Jo, VY, Lowe, AC, Hollowell, M, Qian, X, Wieczorek, TJ, French, CA, Teot, LA, Sadow, PM, Alexander, EK, Cibas, ES, Barletta, JA, and Krane, JF. "Preoperative Cytologic Diagnosis of Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features: A Prospective Analysis." Thyroid : Official Journal of the American Thyroid Association 26, no. 10 (October 2016): 1466-1471. Full Text Open Access Copy
  - Ritterhouse, LL, Nowak, JA, Strickland, KC, Garcia, EP, Jia, Y, Lindeman, NI, Macconaill, LE, Konstantinopoulos, PA, Matulonis, UA, Liu, J, Berkowitz, RS, Nucci, MR, Crum, CP, Sholl, LM, and Howitt, BE. "Morphologic correlates of molecular alterations in extrauterine Müllerian carcinomas." Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 29, no. 8 (August 2016): 893-903. Full Text Open Access Copy
  - Strickland, KC, Watkins, JC, Couper, GS, Givertz, MM, and Padera, RF. "Thrombus around the redesigned HeartWare HVAD inflow cannula: A pathologic case series." The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation 35, no. 7 (July 2016): 926-930. (Letter) Full Text Open Access Copy
  - Wong, KS, Angell, TE, Strickland, KC, Alexander, EK, Cibas, ES, Krane, JF, and Barletta, JA. "Noninvasive Follicular Variant of Papillary Thyroid Carcinoma and the Afirma Gene-Expression Classifier." Thyroid : Official Journal of the American Thyroid Association 26, no. 7 (July 2016): 911-915. Full Text Open Access Copy
  - Strickland, KC, Howitt, BE, Shukla, SA, Rodig, S, Ritterhouse, LL, Liu, JF, Garber, JE, Chowdhury, D, Wu, CJ, D'Andrea, AD, Matulonis, UA, and Konstantinopoulos, PA. "Association and prognostic significance of BRCA1/2-mutation status with neoantigen load, number of tumor-infiltrating lymphocytes and expression of PD-1/PD-L1 in high grade serous ovarian cancer." Oncotarget 7, no. 12 (March 2016): 13587-13598. Full Text Open Access Copy
  - Strickland, KC, Nucci, MR, Esselen, KM, Muto, MG, Chopra, S, George, S, and Howitt, BE. "Solitary Fibrous Tumor of the Uterus Presenting With Lung Metastases: A Case Report." International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 35, no. 1 (January 2016): 25-29. Full Text Open Access Copy
  - Howitt, BE, Shukla, SA, Sholl, LM, Ritterhouse, LL, Watkins, JC, Rodig, S, Stover, E, Strickland, KC, D'Andrea, AD, Wu, CJ, Matulonis, UA, and Konstantinopoulos, PA. "Association of Polymerase e-Mutated and Microsatellite-Instable Endometrial Cancers With Neoantigen Load, Number of Tumor-Infiltrating Lymphocytes, and Expression of PD-1 and PD-L1." Jama Oncology 1, no. 9 (December 2015): 1319-1323. Full Text Open Access Copy
  - Strickland, KC, Howitt, BE, Marqusee, E, Alexander, EK, Cibas, ES, Krane, JF, and Barletta, JA. "The Impact of Noninvasive Follicular Variant of Papillary Thyroid Carcinoma on Rates of Malignancy for Fine-Needle Aspiration Diagnostic Categories." Thyroid : Official Journal of the American Thyroid Association 25, no. 9 (September 2015): 987-992. Full Text Open Access Copy
  - Strickland, KC, Krupenko, NI, and Krupenko, SA. "Molecular mechanisms underlying the potentially adverse effects of folate." Clinical chemistry and laboratory medicine 51, no. 3 (March 2013): 607-616. (Review) Full Text Open Access Copy
  - Tsybovsky, Y, Malakhau, Y, Strickland, KC, and Krupenko, SA. "The mechanism of discrimination between oxidized and reduced coenzyme in the aldehyde dehydrogenase domain of Aldh1l1." Chemico-biological interactions 202, no. 1-3 (February 2013): 62-69. Full Text Open Access Copy
  - Strickland, KC, Holmes, RS, Oleinik, NV, Krupenko, NI, and Krupenko, SA. "Phylogeny and evolution of aldehyde dehydrogenase-homologous folate enzymes." Chemico-biological interactions 191, no. 1-3 (May 2011): 122-128. Full Text Open Access Copy
  - Strickland, KC, Krupenko, NI, Dubard, ME, Hu, CJ, Tsybovsky, Y, and Krupenko, SA. "Enzymatic properties of ALDH1L2, a mitochondrial 10-formyltetrahydrofolate dehydrogenase." Chemico-biological interactions 191, no. 1-3 (May 2011): 129-136. Full Text Open Access Copy
  - Krupenko, NI, Dubard, ME, Strickland, KC, Moxley, KM, Oleinik, NV, and Krupenko, SA. "ALDH1L2 is the mitochondrial homolog of 10-formyltetrahydrofolate dehydrogenase." The Journal of Biological Chemistry 285, no. 30 (July 2010): 23056-23063. Full Text Open Access Copy
  - Strickland, KC, Hoeferlin, LA, Oleinik, NV, Krupenko, NI, and Krupenko, SA. "Acyl carrier protein-specific 4'-phosphopantetheinyl transferase activates 10-formyltetrahydrofolate dehydrogenase." The Journal of biological chemistry 285, no. 3 (January 2010): 1627-1633. Full Text Open Access Copy
  - Dellis, S, Strickland, KC, McCrary, WJ, Patel, A, Stocum, E, and Wright, CF. "Protein interactions among the vaccinia virus late transcription factors." Virology 329, no. 2 (November 2004): 328-336. Full Text Open Access Copy

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Education, Training, & Certifications

Selected Grants

Selected Publications

Conference Papers

Journal Articles