Overview
Dr. Margeaux W. Marbrey received her PhD from Baylor College of Medicine while studying how progesterone signaling regulates implantation in a spatiotemporal manner under the mentorship of Dr. Francesco DeMayo. Dr. Marbrey then completed a postdoctoral fellowship at the University of North Carolina Chapel Hill School of Medicine with Dr. Kathleen Caron discerning effects of toxicants, environmental exposures, and tobacco products on pregnancy health, timing, and disease.
The chief aim of the Marbrey Laboratory is to understand molecular regulators of early and mid pregnancy success using exposure paradigms and cutting-edge models to further understand human reproduction, promote healthy pregnancies, and improve patient care. The Marbrey laboratory builds upon Dr. Marbrey's strong experience using innovative models and exposure systems to answer important questions in pregnancy that ultimately lead to public health awareness, risk assessment, and preserved lives of mother and baby.
The chief aim of the Marbrey Laboratory is to understand molecular regulators of early and mid pregnancy success using exposure paradigms and cutting-edge models to further understand human reproduction, promote healthy pregnancies, and improve patient care. The Marbrey laboratory builds upon Dr. Marbrey's strong experience using innovative models and exposure systems to answer important questions in pregnancy that ultimately lead to public health awareness, risk assessment, and preserved lives of mother and baby.
Current Appointments & Affiliations
Assistant Professor in Obstetrics and Gynecology
·
2023 - Present
Obstetrics and Gynecology, Reproductive Sciences,
Obstetrics and Gynecology
Assistant Professor in the Division of Environmental Science and Policy
·
2024 - Present
Environmental Sciences and Policy,
Nicholas School of the Environment
Recent Publications
AHR activated placental adrenomedullin: A plausible factor in smoke-induced preeclampsia protection.
Journal Article Placenta · June 26, 2025 INTRODUCTION: The placenta develops as trophectoderm cells invade and secrete peptides to remodel the maternal vasculature. Impaired invasion can lead to preeclampsia. Maternal smoking during pregnancy can cause miscarriage and fetal developmental problems ... Full text Link to item CiteCoumestrol induces oxidative stress and impairs migration and embryonic growth.
Journal Article Reproduction · July 1, 2023 IN BRIEF: Healthy development of the placenta is dependent on trophoblast cell migration and reduced oxidative stress presence. This article describes how a phytoestrogen found in spinach and soy causes impaired placental development during pregnancy. ABST ... Full text Link to item CiteThe role of epithelial progesterone receptor isoforms in embryo implantation.
Journal Article iScience · December 17, 2021 The loss of uterine epithelial progesterone receptor (PGR) is crucial for successful embryo implantation in both humans and mice. The two major isoforms PGRA and PGRB have divergent functions under both physiological and pathological conditions. The presen ... Full text Link to item CiteRecent Grants
Investigating Implications of E-Cigarettes on Pregnancy Success and Reproductive Fitness
ResearchPrincipal Investigator · Awarded by Eunice Kennedy Shriver National Institute of Child Health and Human Development · 2023 - 2026View All Grants
Education, Training & Certifications
Baylor, College of Medicine ·
2016
Ph.D.