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Michael Joseph Smith

Professor of Pediatrics
Pediatrics, Infectious Diseases

Selected Grants


CISA 2023 Clinical Contributing Task 1

ResearchPrincipal Investigator · Awarded by Centers for Disease Control and Prevention · 2023 - 2028

CISA 2023 Clinical Contributing Task 2

ResearchPrincipal Investigator · Awarded by Centers for Disease Control and Prevention · 2023 - 2028

Clinical and host microbiome features in the development of acute otitis media

ResearchAdvisor · Awarded by National Institute of Allergy and Infectious Diseases · 2023 - 2028

CIVICS Component C - Option 8B.2 Phase 1

ResearchInvestigator · Awarded by National Institutes of Health · 2026 - 2028

CISA 2024 RSV Infants Nirsevimab Study Task 1 - Lead

ResearchPrincipal Investigator · Awarded by Centers for Disease Control and Prevention · 2024 - 2027

MK-8228 (letermovir) PK in pediatric kidney transplant recipients

Clinical TrialPrincipal Investigator · Awarded by Merck Sharp & Dohme LLC · 2025 - 2027

Phase 1: A Safety and Immunogenicity Trial of Boost-2867 Vaccine, Via Intranasal and Intramuscular Routes

ResearchInvestigator · Awarded by Leidos Biomedical Research, Inc. · 2026 - 2026

CIVICs Component C Year 7 - Option 6

ResearchInvestigator · Awarded by National Institutes of Health · 2019 - 2026

CIVICS Component C - Option 9

ResearchInvestigator · Awarded by National Institutes of Health · 2020 - 2026

Lead Site Optional Task 1: Babies COVID-19 Vaccination

ResearchPrincipal Investigator · Awarded by Centers for Disease Control and Prevention · 2022 - 2025

Neutralizing antibody vaccine for pandemic and pre-emergent coronaviruses - Option 1

ResearchInvestigator · Awarded by National Institutes of Health · 2022 - 2025

CIVICS Component C - Option 8

ResearchInvestigator · Awarded by National Institutes of Health · 2020 - 2024

CISA COVID Peds Immunogenicity

ResearchPrincipal Investigator · Awarded by Centers for Disease Control and Prevention · 2022 - 2024

CISA 10-Pediatric COVID-19 Vaccination (Lead)

ResearchPrincipal Investigator · Awarded by Centers for Disease Control and Prevention · 2021 - 2024

Pfizer C4671026

Clinical TrialPrincipal Investigator · Awarded by Pfizer, Inc. · 2022 - 2024

Neutralizing antibody vaccine for pandemic and pre-emergent coronaviruses - Option 4

ResearchInvestigator · Awarded by National Institutes of Health · 2023 - 2024

CISA Consult 2022 Contributing Task 3

Clinical TrialPrincipal Investigator · Awarded by Centers for Disease Control and Prevention · 2022 - 2023

CISA Consult 2022 Contributing Task 1

ResearchPrincipal Investigator · Awarded by Centers for Disease Control and Prevention · 2022 - 2023

Leveraging National Healthcare Safety Network Antimicrobial Use Option to Inform, Implement and Assess Antibiotic Stewardship Activities

ResearchConsultant · Awarded by Centers for Disease Control and Prevention · 2022 - 2023

CISA RFTP Syncope Prevention Study (Lead) 2020-2022

ResearchInvestigator · Awarded by Centers for Disease Control and Prevention · 2020 - 2022

Clinical Vaccine Safety Evaluation - Contributing Site - Task COVID - Optional Task 3

ResearchCo Investigator · Awarded by Centers for Disease Control and Prevention · 2020 - 2022

FY21 and FY22 Improving Care Quality for Children 50/50

ResearchPrincipal Investigator · Awarded by University of Louisville Research Foundation, Inc. · 2020 - 2022

The impact of a provider feedback intervention on inappropriate antibiotic prescribing in Kentucky children: An interrupted time series analysis

ResearchPrincipal Investigator · Awarded by University of Louisville Research Foundation, Inc. · 2021 - 2022

Evaluating SARS-CoV2 vaccine effectiveness among health care personnel during early phase vaccination

ResearchInvestigator · Awarded by Centers for Disease Control and Prevention · 2020 - 2021

VTEU Task Area A - FY.2020.A1B1C1D1.0123 - Option 1

ResearchInvestigator · Awarded by National Institutes of Health · 2020 - 2021

Characterizing Health Disparities in the Shift to North Carolina Medicaid Managed Care

ResearchInvestigator · Awarded by Kate B. Reynolds Charitable Trust · 2020 - 2021

VTEU Protocol Implementation Option 1

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2019 - 2021

A cross-sectional analysis of inappropriate outpatient antibiotic use in children insured by Kentucky Medicaid

ResearchPrincipal Investigator · Awarded by University of Louisville Research Foundation, Inc. · 2020 - 2021

VTEU Task Area A - FY.2020.A1B1C1D1.0123 - Base

ResearchInvestigator · Awarded by National Institutes of Health · 2019 - 2020

Improving Care Quality for Children Receiving Kentucky Medicaid

ResearchPrincipal Investigator · Awarded by University of Louisville Research Foundation, Inc. · 2019 - 2020

VTEU Task Order 18-0011.B1.C1.0116-Task B Base

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2018 - 2019

VTEU RTOP FY.2019.A1B1C1D1.0103 - Task A - Base

ResearchInvestigator · Awarded by National Institutes of Health · 2018 - 2019

Improving Care Quality for Children Receiving Kentucky Medicaid

ResearchPrincipal Investigator · Awarded by University of Louisville Research Foundation, Inc. · 2017 - 2019

VTEU Task Order 16-0047.C1.0090

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2018 - 2018

VTEU Task Order 16-0047 -Task C Option 1

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2018 - 2018

External Relationships


  • Merck

This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.