Overview
Dr. Tadross' lab develops technologies to rapidly deliver drugs to genetically defined subsets of cells in the brain. By using these reagents in mouse models of neuropsychiatric disease, his group is mapping how specific receptors on defined cells and synapses in the brain give rise to diverse neural computations and behaviors. The approach leverages drugs currently in use to treat human neuropsychiatric disease, facilitating clinically relevant interpretation of the mapping effort.
He received his B.S. degree in Electrical & Computer Engineering at Rutgers University, an M.D.-Ph.D. degree in Biomedical Engineering at the Johns Hopkins School of Medicine, and completed his postdoctoral study in Cellular Neuroscience at Stanford University. He began his independent research program as a fellow at the HHMI Janelia Research Campus.
He received his B.S. degree in Electrical & Computer Engineering at Rutgers University, an M.D.-Ph.D. degree in Biomedical Engineering at the Johns Hopkins School of Medicine, and completed his postdoctoral study in Cellular Neuroscience at Stanford University. He began his independent research program as a fellow at the HHMI Janelia Research Campus.
Current Appointments & Affiliations
Assistant Professor in Neurosurgery
·
2025 - Present
Neurosurgery,
Neurosurgery
Assistant Professor of Biomedical Engineering
·
2025 - Present
Biomedical Engineering,
Pratt School of Engineering
Recent Publications
Behavioral state and stimulus strength regulate the role of somatostatin interneurons in stabilizing network activity.
Journal Article Cell Rep · July 22, 2025 Inhibition stabilization enables cortical circuits to encode sensory signals across diverse contexts. Somatostatin-expressing (SST) interneurons are well suited for this role through their strong recurrent connectivity with excitatory pyramidal cells. We t ... Full text Link to item CiteKetamine rescues anhedonia by cell-type- and input-specific adaptations in the nucleus accumbens.
Journal Article Neuron · May 7, 2025 Ketamine is recognized as a rapid and sustained antidepressant, particularly for major depression unresponsive to conventional treatments. Anhedonia is a common symptom of depression for which ketamine is highly efficacious, but the underlying circuits and ... Full text Link to item CiteDISENTANGLING 3D ANIMAL POSE DYNAMICS WITH SCRUBBED CONDITIONAL LATENT VARIABLES
Conference 13th International Conference on Learning Representations Iclr 2025 · January 1, 2025 Methods for tracking lab animal movements in unconstrained environments have become increasingly common and powerful tools for neuroscience. The prevailing hypothesis is that animal behavior in these environments comprises sequences of discrete stereotyped ... CiteRecent Grants
ElectroGLuE
FellowshipPrincipal Investigator · Awarded by Burroughs Wellcome Fund · 2025 - 2027DART.3-Revolutionizing Neuropsychiatric Treatment through Noninvasive, Programmable Cell-Type-Specific Neuropharmacology
ResearchPrincipal Investigator · Awarded by National Institute of Mental Health · 2024 - 2027Unmasking neuromodulatory control of locomotion
ResearchPrincipal Investigator · Awarded by Washington University in St. Louis · 2024 - 2027View All Grants
Education, Training & Certifications
Johns Hopkins University ·
2009
M.D.
Johns Hopkins University ·
2009
Ph.D.