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Michael Raphael Tadross

Assistant Professor of Biomedical Engineering
Biomedical Engineering

Research Interests


Our goal is to bridge the gap between the study of brain as a computational device and the search for novel neuropathological treatments. We develop technologies to manipulate molecules, cells, and synapses in the brain, and deploy these reagents in mouse models of disease.

Selected Grants


CB1 receptors mediate metaplasticity in the cerebellar circuit

ResearchPrincipal Investigator · Awarded by University of Texas Health Science Center at San Antonio · 2024 - 2028

University Training Program in Biomolecular and Tissue Engineering

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 1994 - 2027

Neuroactive steroids as novel psychiatric treatments: mechanistic studies

ResearchPrincipal Investigator · Awarded by Washington University in St. Louis · 2021 - 2026

High-resolution measurement of natural stimuli and ethologically relevant behavior as platform for understanding the nervous system

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2024 - 2026

Interrogating the cholinergic basis of opioid reinforcement with subcellular precision

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2020 - 2025

CB1 receptors mediate metaplasticity in the cerebellar circuit

ResearchPrincipal Investigator · Awarded by University of Texas Health Science Center at San Antonio · 2024 - 2028

University Training Program in Biomolecular and Tissue Engineering

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 1994 - 2027

Neuroactive steroids as novel psychiatric treatments: mechanistic studies

ResearchPrincipal Investigator · Awarded by Washington University in St. Louis · 2021 - 2026

High-resolution measurement of natural stimuli and ethologically relevant behavior as platform for understanding the nervous system

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2024 - 2026

Interrogating the cholinergic basis of opioid reinforcement with subcellular precision

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2020 - 2025

Combating obesity via cell-specific pharmacology of dopamine neurons

FellowshipPrincipal Investigator · Awarded by American Heart Association · 2023 - 2024

CIRCUIT MECHANISMS FOR DOPAMINE NEURON VULNERABILITY AND RESILIENCE IN PD

ResearchCo Investigator · Awarded by Michael J. Fox Foundation for Parkinson's Research · 2021 - 2024

GRIP Display NCBioTech

ResearchPrincipal Investigator · Awarded by North Carolina Biotechnology Center · 2023 - 2024

Neurobiology Training Program

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2019 - 2024

Parvalbumin interneurons regulate nucleus accumbens synapses and behavior

ResearchPrincipal Investigator · Awarded by Vanderbilt University Medical Center · 2021 - 2024

Cerebellar pathology in the absence of plasticity gating

ResearchPrincipal Investigator · Awarded by University of Texas Health Science Center at San Antonio · 2021 - 2024

Receptive field coordination across mosaics of diverse retinal ganglion cell types in the mammalian retina

ResearchCollaborator · Awarded by National Institutes of Health · 2020 - 2024

Evaluating cell type-specific non-dopaminergics as a Parkinson's treatment paradigm

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2021 - 2023

Striatal Microcircuit Drivers of Adaptive Learning in Habit Formation

ResearchCo Investigator · Awarded by National Institutes of Health · 2018 - 2023

Significance of excitatory and inhibitory synaptic integration by interneurons for local circuit dynamics and behavior

FellowshipCo-Sponsor · Awarded by National Institutes of Health · 2020 - 2023

Interrogating dynamics of whole-brain volumes with cell type-specific pharmacology

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2018 - 2023

DART2.0: comprehensive cell type-specific behavioral neuropharmacology

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2018 - 2022

Deconstructing the Behavioral Neuropharmacology of Parkinson's Disease

ResearchPrincipal Investigator · Awarded by Parkinson's Disease Foundation · 2017 - 2020

Interrogating brain dynamics with cell type-specific pharmacology

ResearchPrincipal Investigator · Awarded by Whitehall Foundation, Inc. · 2018 - 2019