Overview
Miguel A. Materin, MD serves as Division Chief of Ocular Oncology, Professor of Ophthalmology, Professor of Radiation Oncology at Duke Eye Center.
His full-time clinical practice involves diagnosis and treatment of patients with ocular tumors. He specializes in ocular melanoma, retinoblastoma, choroidal hemangioma, retinal hemangioblastoma, ocular metastases, astrocytic retinal tumors and tumors related to other conditions or syndromes, such as von Hippel Lindau disease, Tuberous Sclerosis among others.
Dr. Materin joined Duke in September 2016 from Yale University School of Medicine where he was an Associate Professor of Ophthalmology & Visual Science, and Director of Ophthalmic Oncology at Smilow Cancer Hospital at Yale New Haven.
Prior to his appointment at Yale, he was the Director of Diagnostic Studies and Research Fellows for the Ocular Oncology Service at Wills Eye Hospital at Thomas Jefferson University in Philadelphia, where he completed his fellowship in ocular oncology in 1999.
He is an internationally recognized ocular oncologist who has more than 100 publications in peer-reviewed literature, including journals and book chapters. Dr. Materin has been invited as a visiting professor in the U.S., Canada, Israel, Spain, Brazil, Puerto Rico, Argentina, and has given more than 300 lectures.
Dr. Materin received the Achievement Award and Senior Achievement Award from the American Academy of Ophthalmology. He is a Member of Merit of Clinica Barraquer (Barcelona, Spain) and Colombian Society of Ophthalmology. He is an active member of the International Society of Ocular Oncology, American Academy of Ophthalmology, Pan American Association of Ophthalmology.
Dr. Materin served on the education committee of the American Association of Ocular Oncology and Pathology and is past-President of the Pan American Society of Ocular Oncology. He is a Panel Member of the National Comprehensive Cancer Network for Uveal Melanoma.
Current Appointments & Affiliations
Recent Publications
Yttrium-90 (90Y) brachytherapy for squamous carcinoma: Treatment of the conjunctiva, cornea, and sclera.
Journal Article Am J Ophthalmol Case Rep · December 2024 PURPOSE: Patients with conjunctival squamous cell carcinoma that present with persisting disease or recurrence following topical chemotherapy and/or surgery especially when invading the sclera are challenging to treat. Herein, we describe the use of high-d ... Full text Link to item Cite15-Gene Expression Profile and PRAME as Integrated Prognostic Test for Uveal Melanoma: First Report of Collaborative Ocular Oncology Group Study No. 2 (COOG2.1).
Journal Article J Clin Oncol · October 2024 PURPOSEValidated and accurate prognostic testing is critical for precision medicine in uveal melanoma (UM). Our aims were to (1) prospectively validate an integrated prognostic classifier combining a 15-gene expression profile (15-GEP) and PRAME RNA expres ... Full text Link to item CiteMelanocytic Nevus of the Superior Conjunctival Fornix: A Case Report.
Journal Article Case Rep Ophthalmol · 2024 INTRODUCTION: Conjunctival nevi are benign tumors that are commonly located at the nasal or temporal limbus and rarely in the fornix or tarsus. We report a case of a patient presenting with a solitary compound cystic nevus of the conjunctival fornix in the ... Full text Link to item CiteRecent Grants
A Phase 3 Randomized, Masked, Controlled Trial to Evaluate Efficacy and Safety of Belzupacap Sarotalocan (AU-011) Treatment Compared to Sham Control in Subjects with Primary Indeterminate Lesions or Small Choroidal Melanoma
Clinical TrialPrincipal Investigator · Awarded by Aura Biosciences, Inc. · 2024 - 2029Retinoblastoma Patient Clinical Database and Tissue Repository
ResearchPrincipal Investigator · Awarded by Children's Hospital Los Angeles · 2024 - 2025View All Grants