Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Postdoctoral Research Fellow, Psychiatry, National Institutes of Health 1997 - 1998
  • Resident, Division of Child and Adolescent Psychiatry, Psychiatry, Children's Hospital of Philadelphia 1995 - 1997
  • Chief Resident, Psychiatry, Psychiatry, University of Pennsylvania, School of Medicine 1994 - 1995
  • Resident, Adult Psychiatry, Psychiatry, University of Pennsylvania, School of Medicine 1992 - 1995
  • Intern in Psychiatry, Psychiatry, University of Pennsylvania, School of Medicine 1991 - 1992
  • M.D., Rutgers, New Jersey Medical School 1991
• 

  Leadership & Clinical Positions at Duke

  • Chair, Department of Psychiatry and Behavioral Sciences
• Research
• 

  External Relationships

  • Allergan, Inc.
  • Boston Children's Hospital
  • Boston's Childrens Hospital
  • DC National Children's Hosptial
  • Sheppard Pratt Hospital
  • UpToDate
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Cyr, Marilyn, David Pagliaccio, Paula Yanes-Lukin, Martine Fontaine, Moira A. Rynn, and Rachel Marsh. “Altered network connectivity predicts response to cognitive-behavioral therapy in pediatric obsessive-compulsive disorder.” Neuropsychopharmacology 45, no. 7 (June 2020): 1232–40. https://doi.org/10.1038/s41386-020-0613-3.
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    • Cyr, Marilyn, David Pagliaccio, Paula Yanes-Lukin, Martine Fontaine, Moira A. Rynn, and Rachel Marsh. “Correction: Altered network connectivity predicts response to cognitive-behavioral therapy in pediatric obsessive-compulsive disorder.” Neuropsychopharmacology 45, no. 7 (June 2020): 1241. https://doi.org/10.1038/s41386-020-0647-6.
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    • Pagliaccio, David, Jiook Cha, Xiaofu He, Marilyn Cyr, Paula Yanes-Lukin, Pablo Goldberg, Martine Fontaine, Moira A. Rynn, and Rachel Marsh. “Structural neural markers of response to cognitive behavioral therapy in pediatric obsessive-compulsive disorder.” J Child Psychol Psychiatry, December 31, 2019. https://doi.org/10.1111/jcpp.13191.
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    • Sanchez, Amanda L., Jonathan S. Comer, Stefany Coxe, Anne Marie Albano, John Piacentini, Scott N. Compton, Golda S. Ginsburg, et al. “The Effects of Youth Anxiety Treatment on School Impairment: Differential Outcomes Across CBT, Sertraline, and their Combination.” Child Psychiatry Hum Dev 50, no. 6 (December 2019): 940–49. https://doi.org/10.1007/s10578-019-00896-3.
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    • Mufson, Laura, and Moira A. Rynn. “Primary Care: Meeting the Mental Health Care Needs of Adolescents With Depression.” J Am Acad Child Adolesc Psychiatry 58, no. 4 (April 2019): 389–91. https://doi.org/10.1016/j.jaac.2018.10.014.
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    • Albano, Anne Marie, Jonathan S. Comer, Scott N. Compton, John Piacentini, Philip C. Kendall, Boris Birmaher, John T. Walkup, et al. “Secondary Outcomes From the Child/Adolescent Anxiety Multimodal Study: Implications for Clinical Practice.” Evid Based Pract Child Adolesc Ment Health 3, no. 1 (2018): 30–41. https://doi.org/10.1080/23794925.2017.1399485.
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    • Kiff, Cara J., Stephanie Ernestus, Araceli Gonzalez, Philip C. Kendall, Anne Marie Albano, Scott N. Compton, Boris Birmaher, et al. “The Interplay of Familial and Individual Risk in Predicting Clinical Improvements in Pediatric Anxiety Disorders.” J Clin Child Adolesc Psychol 47, no. sup1 (2018): S542–54. https://doi.org/10.1080/15374416.2018.1460848.
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    • Strawn, Jeffrey R., Eric T. Dobson, Jeffrey A. Mills, Gary J. Cornwall, Dara Sakolsky, Boris Birmaher, Scott N. Compton, et al. “Placebo Response in Pediatric Anxiety Disorders: Results from the Child/Adolescent Anxiety Multimodal Study.” J Child Adolesc Psychopharmacol 27, no. 6 (August 2017): 501–8. https://doi.org/10.1089/cap.2016.0198.
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    • Strawn, Jeffrey R., Scott N. Compton, Brigitte Robertson, Anne Marie Albano, Mohamed Hamdani, and Moira A. Rynn. “Extended Release Guanfacine in Pediatric Anxiety Disorders: A Pilot, Randomized, Placebo-Controlled Trial.” J Child Adolesc Psychopharmacol 27, no. 1 (February 2017): 29–37. https://doi.org/10.1089/cap.2016.0132.
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    • Peris, Tara S., Scott N. Compton, Philip C. Kendall, Boris Birmaher, Joel Sherrill, John March, Elizabeth Gosch, et al. “Trajectories of change in youth anxiety during cognitive-behavior therapy.” J Consult Clin Psychol 83, no. 2 (April 2015): 239–52. https://doi.org/10.1037/a0038402.
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    • Read, Kendra L., Cara A. Settipani, Jeremy Peterman, Philip C. Kendall, Scott Compton, John Piacentini, James McCracken, et al. “Predicting Anxiety Diagnoses and Severity with the CBCL-A: Improvement Relative to Other CBCL Scales?” J Psychopathol Behav Assess 37, no. 1 (March 1, 2015): 100–111. https://doi.org/10.1007/s10862-014-9439-9.
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    • Rynn, Moira A., John T. Walkup, Scott N. Compton, Dara J. Sakolsky, Joel T. Sherrill, Sa Shen, Philip C. Kendall, et al. “Child/Adolescent anxiety multimodal study: evaluating safety.” J Am Acad Child Adolesc Psychiatry 54, no. 3 (March 2015): 180–90. https://doi.org/10.1016/j.jaac.2014.12.015.
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    • Strawn, Jeffrey R., Jeffrey A. Welge, Anna M. Wehry, Brooks Keeshin, and Moira A. Rynn. “Efficacy and tolerability of antidepressants in pediatric anxiety disorders: a systematic review and meta-analysis.” Depress Anxiety 32, no. 3 (March 2015): 149–57. https://doi.org/10.1002/da.22329.
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    • Gonzalez, Araceli, Tara S. Peris, Allison Vreeland, Cara J. Kiff, Philip C. Kendall, Scott N. Compton, Anne Marie Albano, et al. “Parental anxiety as a predictor of medication and CBT response for anxious youth.” Child Psychiatry Hum Dev 46, no. 1 (February 2015): 84–93. https://doi.org/10.1007/s10578-014-0454-6.
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    • Reyes-Portillo, Jazmin A., Laura Mufson, Laurence L. Greenhill, Madelyn S. Gould, Prudence W. Fisher, Naomi Tarlow, and Moira A. Rynn. “Web-based interventions for youth internalizing problems: a systematic review.” J Am Acad Child Adolesc Psychiatry 53, no. 12 (December 2014): 1254-1270.e5. https://doi.org/10.1016/j.jaac.2014.09.005.
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    • Crawley, Sarah A., Nicole E. Caporino, Boris Birmaher, Golda Ginsburg, John Piacentini, Anne Marie Albano, Joel Sherrill, et al. “Somatic complaints in anxious youth.” Child Psychiatry Hum Dev 45, no. 4 (August 2014): 398–407. https://doi.org/10.1007/s10578-013-0410-x.
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    • Compton, Scott N., Tara S. Peris, Daniel Almirall, Boris Birmaher, Joel Sherrill, Phillip C. Kendall, John S. March, et al. “Predictors and moderators of treatment response in childhood anxiety disorders: results from the CAMS trial.” J Consult Clin Psychol 82, no. 2 (April 2014): 212–24. https://doi.org/10.1037/a0035458.
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    • Ginsburg, Golda S., Emily M. Becker, Courtney P. Keeton, Dara Sakolsky, John Piacentini, Anne Marie Albano, Scott N. Compton, et al. “Naturalistic follow-up of youths treated for pediatric anxiety disorders.” Jama Psychiatry 71, no. 3 (March 2014): 310–18. https://doi.org/10.1001/jamapsychiatry.2013.4186.
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    • Piacentini, John, Shannon Bennett, Scott N. Compton, Phillip C. Kendall, Boris Birmaher, Anne Marie Albano, John March, et al. “24- and 36-week outcomes for the Child/Adolescent Anxiety Multimodal Study (CAMS).” J Am Acad Child Adolesc Psychiatry 53, no. 3 (March 2014): 297–310. https://doi.org/10.1016/j.jaac.2013.11.010.
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    • Beidas, Rinad S., Oliver Lindhiem, Douglas M. Brodman, Anna Swan, Matthew Carper, Colleen Cummings, Philip C. Kendall, et al. “A probabilistic and individualized approach for predicting treatment gains: an extension and application to anxiety disordered youth.” Behav Ther 45, no. 1 (January 2014): 126–36. https://doi.org/10.1016/j.beth.2013.05.001.
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    • Wei, Chiaying, Alexandra Hoff, Marianne A. Villabø, Jeremy Peterman, Philip C. Kendall, John Piacentini, James McCracken, et al. “Assessing anxiety in youth with the multidimensional anxiety scale for children.” J Clin Child Adolesc Psychol 43, no. 4 (2014): 566–78. https://doi.org/10.1080/15374416.2013.814541.
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    • Cummings, Colleen M., Nicole E. Caporino, Cara A. Settipani, Kendra L. Read, Scott N. Compton, John March, Joel Sherrill, et al. “The therapeutic relationship in cognitive-behavioral therapy and pharmacotherapy for anxious youth.” J Consult Clin Psychol 81, no. 5 (October 2013): 859–64. https://doi.org/10.1037/a0033294.
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    • Keeton, Courtney P., Golda S. Ginsburg, Kelly L. Drake, Dara Sakolsky, Philip C. Kendall, Boris Birmaher, Anne Marie Albano, et al. “Benefits of child-focused anxiety treatments for parents and family functioning.” Depress Anxiety 30, no. 9 (September 2013): 865–72. https://doi.org/10.1002/da.22055.
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    • Podell, Jennifer L., Philip C. Kendall, Elizabeth A. Gosch, Scott N. Compton, John S. March, Anne-Marie Albano, Moira A. Rynn, et al. “Therapist Factors and Outcomes in CBT for Anxiety in Youth.” Prof Psychol Res Pr 44, no. 2 (April 2013): 89–98. https://doi.org/10.1037/a0031700.
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    • Caporino, Nicole E., Douglas M. Brodman, Philip C. Kendall, Anne Marie Albano, Joel Sherrill, John Piacentini, Dara Sakolsky, et al. “Defining treatment response and remission in child anxiety: signal detection analysis using the pediatric anxiety rating scale.” J Am Acad Child Adolesc Psychiatry 52, no. 1 (January 2013): 57–67. https://doi.org/10.1016/j.jaac.2012.10.006.
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    • Rickels, Karl, Bijan Etemad, Moira A. Rynn, Falk W. Lohoff, Laura A. Mandos, and Robert Gallop. “Remission of generalized anxiety disorder after 6 months of open-label treatment with venlafaxine XR.” Psychother Psychosom 82, no. 6 (2013): 363–71. https://doi.org/10.1159/000351410.
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    • Almirall, Daniel, Scott N. Compton, Moira A. Rynn, John T. Walkup, and Susan A. Murphy. “SMARTer discontinuation trial designs for developing an adaptive treatment strategy.” J Child Adolesc Psychopharmacol 22, no. 5 (October 2012): 364–74. https://doi.org/10.1089/cap.2011.0073.
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    • Rynn, Moira A., Hilary B. Vidair, and Jennifer Urbano Blackford. “Childhood anxiety: lessons learned.” Child Adolesc Psychiatr Clin N Am 21, no. 3 (July 2012): xiii–xv. https://doi.org/10.1016/j.chc.2012.06.001.
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    • Strawn, Jeffrey R., Dara J. Sakolsky, and Moira A. Rynn. “Psychopharmacologic treatment of children and adolescents with anxiety disorders.” Child Adolesc Psychiatr Clin N Am 21, no. 3 (July 2012): 527–39. https://doi.org/10.1016/j.chc.2012.05.003.
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    • Strawn, Jeffrey R., Anna M. Wehry, Melissa P. DelBello, Moira A. Rynn, and Stephen Strakowski. “Establishing the neurobiologic basis of treatment in children and adolescents with generalized anxiety disorder.” Depress Anxiety 29, no. 4 (April 2012): 328–39. https://doi.org/10.1002/da.21913.
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    • Barber, J. P., M. S. Barrett, R. Gallop, M. A. Rynn, and K. Rickels. “Dr Barber and colleagues reply.” Journal of Clinical Psychiatry 73, no. 5 (January 1, 2012): 718–20. https://doi.org/10.4088/JCP.12lr07633a.
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    • Barber, Jacques P., Marna S. Barrett, Robert Gallop, Moira A. Rynn, and Karl Rickels. “Short-term dynamic psychotherapy versus pharmacotherapy for major depressive disorder: a randomized, placebo-controlled trial.” J Clin Psychiatry 73, no. 1 (January 2012): 66–73. https://doi.org/10.4088/JCP.11m06831.
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    • Ginsburg, Golda S., Philip C. Kendall, Dara Sakolsky, Scott N. Compton, John Piacentini, Anne Marie Albano, John T. Walkup, et al. “Remission after acute treatment in children and adolescents with anxiety disorders: findings from the CAMS.” J Consult Clin Psychol 79, no. 6 (December 2011): 806–13. https://doi.org/10.1037/a0025933.
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    • Vidair, Hilary B., Jazmin A. Reyes, Sa Shen, Maria A. Parrilla-Escobar, Charlotte M. Heleniak, Ilene L. Hollin, Scott Woodruff, J Blake Turner, and Moira A. Rynn. “Screening parents during child evaluations: exploring parent and child psychopathology in the same clinic.” J Am Acad Child Adolesc Psychiatry 50, no. 5 (May 2011): 441–50. https://doi.org/10.1016/j.jaac.2011.02.002.
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    • Rickels, Karl, Bijan Etemad, Sarosh Khalid-Khan, Falk W. Lohoff, Moira A. Rynn, and Robert J. Gallop. “Time to relapse after 6 and 12 months' treatment of generalized anxiety disorder with venlafaxine extended release.” Arch Gen Psychiatry 67, no. 12 (December 2010): 1274–81. https://doi.org/10.1001/archgenpsychiatry.2010.170.
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    • Kendall, Philip C., Scott N. Compton, John T. Walkup, Boris Birmaher, Anne Marie Albano, Joel Sherrill, Golda Ginsburg, et al. “Clinical characteristics of anxiety disordered youth.” J Anxiety Disord 24, no. 3 (April 2010): 360–65. https://doi.org/10.1016/j.janxdis.2010.01.009.
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    • Compton, Scott N., John T. Walkup, Anne Marie Albano, John C. Piacentini, Boris Birmaher, Joel T. Sherrill, Golda S. Ginsburg, et al. “Child/Adolescent Anxiety Multimodal Study (CAMS): rationale, design, and methods.” Child Adolesc Psychiatry Ment Health 4 (January 5, 2010): 1. https://doi.org/10.1186/1753-2000-4-1.
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    • Walkup, John T., Anne Marie Albano, John Piacentini, Boris Birmaher, Scott N. Compton, Joel T. Sherrill, Golda S. Ginsburg, et al. “Cognitive behavioral therapy, sertraline, or a combination in childhood anxiety.” N Engl J Med 359, no. 26 (December 25, 2008): 2753–66. https://doi.org/10.1056/NEJMoa0804633.
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    • Roy, Amy Krain, Roma A. Vasa, Maggie Bruck, Karin Mogg, Brendan P. Bradley, Michael Sweeney, R Lindsey Bergman, Erin B. McClure-Tone, Daniel S. Pine, and Daniel S. CAMS Team. “Attention bias toward threat in pediatric anxiety disorders.” J Am Acad Child Adolesc Psychiatry 47, no. 10 (October 2008): 1189–96. https://doi.org/10.1097/CHI.0b013e3181825ace.
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    • Rynn, M. A. “The varied manifestations of anxiety disorder.” Psychiatric Times 25, no. 2 (February 1, 2008).
    • March, John S., A Richard Entusah, Moira Rynn, Anne Marie Albano, and Karen A. Tourian. “A Randomized controlled trial of venlafaxine ER versus placebo in pediatric social anxiety disorder.” Biol Psychiatry 62, no. 10 (November 15, 2007): 1149–54. https://doi.org/10.1016/j.biopsych.2007.02.025.
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    • Rynn, Moira A., Mark A. Riddle, Paul P. Yeung, and Nadia R. Kunz. “Efficacy and safety of extended-release venlafaxine in the treatment of generalized anxiety disorder in children and adolescents: two placebo-controlled trials.” Am J Psychiatry 164, no. 2 (February 2007): 290–300. https://doi.org/10.1176/ajp.2007.164.2.290.
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    • Khalid-Khan, Sarosh, Maria-Paz Santibanez, Carolyn McMicken, and Moira A. Rynn. “Social anxiety disorder in children and adolescents: epidemiology, diagnosis, and treatment.” Paediatr Drugs 9, no. 4 (2007): 227–37. https://doi.org/10.2165/00148581-200709040-00004.
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    • Feiger, Alan D., Karl Rickels, Moira A. Rynn, Dan L. Zimbroff, and Donald S. Robinson. “Selegiline transdermal system for the treatment of major depressive disorder: an 8-week, double-blind, placebo-controlled, flexible-dose titration trial.” J Clin Psychiatry 67, no. 9 (September 2006): 1354–61. https://doi.org/10.4088/jcp.v67n0905.
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    • Rynn, Moira A., Jacques P. Barber, Sarosh Khalid-Khan, Lynne Siqueland, Michelle Dembiski, Kevin S. McCarthy, and Robert Gallop. “The psychometric properties of the MASC in a pediatric psychiatric sample.” J Anxiety Disord 20, no. 2 (2006): 139–57. https://doi.org/10.1016/j.janxdis.2005.01.004.
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    • Snyderman, Steven H., Moira A. Rynn, and Karl Rickels. “Open-label pilot study of ziprasidone for refractory generalized anxiety disorder.” J Clin Psychopharmacol 25, no. 5 (October 2005): 497–99. https://doi.org/10.1097/01.jcp.0000177853.15910.de.
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    • Rynn, Moira A., and Olga Brawman-Mintzer. “Generalized anxiety disorder: acute and chronic treatment.” Cns Spectr 9, no. 10 (October 2004): 716–23. https://doi.org/10.1017/s1092852900022367.
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    • Snyderman, Steven H., Moira A. Rynn, Kevin Bellew, and Karl Rickels. “Paroxetine in the treatment of generalised anxiety disorder.” Expert Opin Pharmacother 5, no. 8 (August 2004): 1799–1806. https://doi.org/10.1517/14656566.5.8.1799.
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    • Ambrosini, P. J., J. Elia, and M. A. Rynn. “49th Annual Meeting of the American Academy of Child & Adolescent Psychiatry. 22-27 October 2002, San Francisco, CA, USA.” Expert Opin Pharmacother 4, no. 4 (April 2003): 591–94. https://doi.org/10.1517/14656566.4.4.591.
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    • Baldassano, C. F., C. Ballas, S. M. Datto, D. Kim, L. Littman, J. O’Reardon, and M. A. Rynn. “Ziprasidone-associated mania: a case series and review of the mechanism.” Bipolar Disord 5, no. 1 (February 2003): 72–75. https://doi.org/10.1034/j.1399-5618.2003.02258.x.
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    • O’Reardon, John P., James M. Hetznecker, Moira A. Rynn, Claudia F. Baldassano, and Martin P. Szuba. “Desipramine toxicity with terbinafine.” Am J Psychiatry 159, no. 3 (March 2002): 492. https://doi.org/10.1176/appi.ajp.159.3.492.
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    • Rynn, M. A., L. Siqueland, and K. Rickels. “Placebo-controlled trial of sertraline in the treatment of children with generalized anxiety disorder.” Am J Psychiatry 158, no. 12 (December 2001): 2008–14. https://doi.org/10.1176/appi.ajp.158.12.2008.
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    • Rickels, K., and M. A. Rynn. “What is generalized anxiety disorder?” J Clin Psychiatry 62 Suppl 11 (2001): 4–12.
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    • Bushnell, Greta A., Scott N. Compton, Stacie B. Dusetzina, Bradley N. Gaynes, M Alan Brookhart, John T. Walkup, Moira A. Rynn, and Til Stürmer. “Treating Pediatric Anxiety: Initial Use of SSRIs and Other Antianxiety Prescription Medications.” J Clin Psychiatry 79, no. 1 (n.d.). https://doi.org/10.4088/JCP.16m11415.
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  • Book Sections

    • Strawn, J. R., E. T. Dobson, A. B. Ramesh, S. A. Berger, and M. A. Rynn. “Pharmacologic treatment of pediatric anxiety disorders.” In Pediatric Anxiety Disorders, 359–84, 2019. https://doi.org/10.1016/B978-0-12-813004-9.00017-7.
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    • Heleniak, C. M., T. Kaur, K. D. Ghalib, and M. A. Rynn. “Tricyclic Antidepressants and Monoamine Oxidase Inhibitors for the Treatment of Child and Adolescent Psychiatric Disorders.” In Pharmacotherapy of Child and Adolescent Psychiatric Disorders: Third Edition, 105–29, 2012. https://doi.org/10.1002/9781119958338.ch7.
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    • Vidair, H. B., and M. A. Rynn. “Childhood anxiety disorders: Best treatment options and practice.” In Anxiety Disorders: Theory, Research, and Clinical Perspectives, 306–22, 2010. https://doi.org/10.1017/CBO9780511777578.029.
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  • Conference Papers

    • Duarte, Cristiane S., Maria C. Zerrate, and Moira A. Rynn. “47.0 Bringing Evidence-Based Treatment to Emerging Adults With Anxiety Disorders in Three Clinical Settings: The Youth Anxiety Center.” In Journal of the American Academy of Child & Adolescent Psychiatry, 55:S71–72. Elsevier BV, 2016. https://doi.org/10.1016/j.jaac.2016.07.719.
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    • Fitzgerald, Kate D., Rachel Marsh, and Moira A. Rynn. “21.0 Abnormal Neural Substrate for Performance Monitoring in Pediatric Obsessive-Compulsive Disorder: Implications for Understanding Treatment Response.” In Journal of the American Academy of Child & Adolescent Psychiatry, 55:S290–S290. Elsevier BV, 2016. https://doi.org/10.1016/j.jaac.2016.07.237.
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    • Marsh, Rachel, Emily J. Steinberg, Pablo H. Goldberg, Paula Yanes-Lukin, Dylan Braun, Chiaying Wei, Christa D. Labouliere, and Moira A. Rynn. “21.1 COGNITIVE-BEHAVIORAL THERAPY–BASED CHANGES IN CONTROL AND REWARD CIRCUITS IN PEDIATRIC OBSESSIVE-COMPULSIVE DISORDER.” In Journal of the American Academy of Child & Adolescent Psychiatry, 55:S290–S290. Elsevier BV, 2016. https://doi.org/10.1016/j.jaac.2016.07.238.
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    • Mufson, Laura, and Moira A. Rynn. “Interpersonal Psychotherapy for Depression: Understanding the Core of the Interpersonal Psychotherapy for Depressed Adolescents Model and Its Adaptations.” In Journal of the American Academy of Child & Adolescent Psychiatry, 55:S38–S38. Elsevier BV, 2016. https://doi.org/10.1016/j.jaac.2016.07.582.
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    • Van Ameringen, M., M. A. Rynn, T. K. Murphy, and F. Mandel. “Influence of gender on the clinical presentation of generalized anxiety disorder, and response to treatment with Pregabalin.” In European Psychiatry, 23:S221–22. Cambridge University Press (CUP), 2008. https://doi.org/10.1016/j.eurpsy.2008.01.390.
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    • Emslie, G. J., R. L. Findling, M. A. Rynn, R. N. Marcus, L. A. Fernandes, M. F. D’Amico, and S. A. Hardy. “Efficacy and safety of nefazadone in the treatment of adolescents with major depressive disorder.” In Journal of Child and Adolescent Psychopharmacology, 12:299–299. MARY ANN LIEBERT INC PUBL, 2002.
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    • Bates, Noelle A., Moira A. Rynn, Daniel H. Conway, Harold W. Lischner, Nicole Hahnlen, and Mark L. Bagarazzi. “Assessment of Psychiatric Comorbidity in Children Infected with Human Immunodeficiency Virus, Type 1.” In Pediatric Research, 45:13A-13A. Springer Science and Business Media LLC, 1999. https://doi.org/10.1203/00006450-199904020-00082.
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