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Paul Hofmann

Assoc Dir, DCRI
Duke Clinical Research Institute
Box 104785, Durham, NC 27710
300 West Morgan St., Suite 800, Durham, NC 27701

Current Duke Appointments & Affiliations


Recent Scholarly Works


Predictors of ischemic stroke and major bleeding among patients with atrial fibrillation in clinical practice.

Journal article Am Heart J · October 2026 BACKGROUND: Numerous risk scores exist to quantify the risk of ischemic stroke risk in patients with atrial fibrillation or flutter (AF/AFL). However, how these tools perform in cohorts or those already on oral anticoagulation (OAC) therapy is unclear. MET ... Full text Link to item Cite

Evaluation, treatment, and outcomes in patients with possible severe aortic stenosis.

Journal article Am Heart J · October 2026 BACKGROUND: Severe aortic stenosis (AS) is associated with significant morbidity and mortality. Prior reports suggest that severe AS is under-recognized and undertreated. METHODS: Retrospective analysis of the Duke Echocardiography Laboratory Database of i ... Full text Link to item Cite

Clinical Patterns and Appropriateness of Apixaban Dosing in Patients With Atrial Fibrillation.

Journal article JACC Adv · June 29, 2026 BACKGROUND: Apixaban is a direct oral anticoagulant for stroke prevention in patients with atrial fibrillation (AF) or atrial flutter (AFL), with dose reduction being recommended based on age, body weight, and creatinine. OBJECTIVES: The objective of the s ... Full text Link to item Cite
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Recent Grants


Power of Bayesian Methods, RCTs, and Decision Models to Inform CRT Uncertainties

ResearchStatistical Programmer · Awarded by National Institutes of Health · 2016 - 2023

SOLI - Solithromycin Pediatric Development Program (Phase 2/3)- Labor & Sub Cost

Clinical TrialStatistical Programmer · Awarded by Cempra Pharmaceuticals, Inc. · 2016 - 2018

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