Scholars@Duke
Rachael Mintz-Cole

Rachael Mintz-Cole

Assistant Professor of Anesthesiology
Anesthesiology, Critical Care Medicine

Selected Publications

Role of heat shock protein and cytokine expression as markers of clinical outcomes with glutamine-supplemented parenteral nutrition in surgical ICU patients.

Journal Article Clin Nutr · February 2020 BACKGROUND: Nutrients, such as glutamine (GLN), have been shown to effect levels of a family of protective proteins termed heat shock proteins (HSPs) in experimental and clinical critical illness. HSPs are believed to serve as extracellular inflammatory me ... Full text Link to item Cite

Transnasal Transsphenoidal Elevation of Optic Chiasm in Secondary Empty Sella Syndrome Following Prolactinoma Treatment.

Journal Article World Neurosurg · April 2018 BACKGROUND: Prolactinomas are typically treated nonsurgically with a dopamine agonist. Once the tumor shrinks, adjacent eloquent structures, such as the optic apparatus, can become skeletonized and herniate into the dilated parasellar space. CASE DESCRIPTI ... Full text Link to item Cite

β-Glucan exacerbates allergic asthma independent of fungal sensitization and promotes steroid-resistant TH2/TH17 responses.

Journal Article J Allergy Clin Immunol · January 2017 BACKGROUND: Allergic sensitization to fungi has been associated with asthma severity. As a result, it has been largely assumed that the contribution of fungi to allergic disease is mediated through their potent antigenicity. OBJECTIVE: We sought to determi ... Full text Link to item Cite

Assessing the immune status of critically ill trauma patients by flow cytometry.

Journal Article Nurs Res · 2014 BACKGROUND: Unintentional injury or trauma remains the leading cause of death among young adults. About one fifth of these trauma patients require care in an intensive care unit (ICU) because of severity of injuries and comorbidities. Patients hospitalized ... Full text Link to item Cite

Surface availability of beta-glucans is critical determinant of host immune response to Cladosporium cladosporioides.

Journal Article J Allergy Clin Immunol · July 2013 BACKGROUND: It is well accepted that mold exposure is a major contributor to the development of asthma, and beta-glucans are often used as a surrogate for mold exposure in the environment. Beta-glucans are an important component of mold spores and are reco ... Full text Link to item Cite

Dectin-1 and IL-17A suppress murine asthma induced by Aspergillus versicolor but not Cladosporium cladosporioides due to differences in β-glucan surface exposure.

Journal Article J Immunol · October 1, 2012 There is considerable evidence supporting a role for mold exposure in the pathogenesis and expression of childhood asthma. Aspergillus versicolor and Cladosporium cladosporioides are common molds that have been implicated in asthma. In a model of mold-indu ... Full text Link to item Cite

DEK proto-oncogene expression interferes with the normal epithelial differentiation program.

Journal Article Am J Pathol · January 2009 Overexpression of the DEK gene is associated with multiple human cancers, but its specific roles as a putative oncogene are not well defined. DEK transcription was previously shown to be induced by the high-risk human papillomavirus (HPV) E7 oncogene via E ... Full text Link to item Cite