Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Postdoctoral Research Fellow on T32 Training Grant, Stanford University, School of Medicine 2016 - 2017
  • BMT Fellowship, Stanford University, School of Medicine 2015 - 2016
  • Hematology/Oncology Fellowship, University of Pittsburgh, School of Medicine 2012 - 2015
  • Internship and Residency in Internal Medicine, St. Luke's Memorial Hospital Center 2009 - 2012
  • M.D., Seoul National University (South Korea) 2002
• 

  Medical Licensure

  • 2017-00624. North Carolina. 2017
• 

  Duke Appointment History

  • Medical Instructor in the Department of Medicine, Medicine, Hematologic Malignancies and Cellular Therapy, Medicine 2017 - 2020
• Recognition
• 

  Awards & Honors

  • Resident of the year 2011-2012. St.Luke's Hospital Residency Program. May 2012
• Expertise
• 

  Subject Headings

  • Cellular therapy
  • Immunotherapy
  • Multiple Myeloma
  • Plasma cell diseases
  • Stem Cell Transplantation
• Research
• 

  Selected Grants

  • Long Term Follow-up Protocol for Subjects Treated with Gene-Modified T Cells awarded by Celgene Corporation 2021 - 2026
  • A Phase I, Open-Label, Multi-Center, Dose Escalation and Dose Expansion Study of NKTR-255 as a single agent in relapsed or refractory hematological malignancies and in combgination with Daratumumab as a Salvage Regimen for Multiple Myeloma awarded by Nektar Therapeutics 2020 - 2025
  • Prospective, Multicenter, Open-Label, Single Arm, Phase 2 Study to Evaluate the Safety and Efficacy of Defibrotide in the Prevention of Chimeric Antigen Receptor-T-cell-associated Neurotoxicity in Subjects with Relapsed or Refractory Diffuse Large B- awarded by Jazz Pharmaceuticals 2019 - 2024
  • A Phase 3, Multicenter, Randomized, Open-Label Study to Compare the Efficacy and Safety of BB2121 Versus Standard Triplet Regimens in Subjects with Relapsed and Refractory Multiple Myeloma (RRMM) (KARMMa-3) awarded by Celgene Corporation 2019 - 2024
• 

  Fellowships, Supported Research, & Other Grants

  • KarMMa-3: a phase 3, multicenter, randomized, open-label study to compare the efficacy and safety of bb2121 versus standard triplet regimens in subjects with relapsed and refractory multiple myeloma awarded by Celgene 2019
  • Prospective, Multicenter, Open-Label, Single Arm, Phase 2 Study to Evaluate the Safety and Efficacy of Defibrotide in Prevention of CAR-T associated Neurotoxicity in Subjects with Relapsed or Refractory DLBCL receiving Axicabtagene Ciloleucel (Yescarta®) awarded by Jazz Pharmaceutical 2019
• 

  External Relationships

  • Janssen Pharmaceuticals
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Racioppi, A., Dalton, T., Ramalingam, S., Romero, K., Ren, Y., Bohannon, L., … Sung, A. D. (2021). Assessing the Feasibility of a Novel mHealth App in Hematopoietic Stem Cell Transplant Patients. Transplantation and Cellular Therapy, 27(2), 181.e1-181.e9. https://doi.org/10.1016/j.jtct.2020.10.017
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    • Choi, T., Choi, I. Y., Han, K., Jeong, S.-M., Yoo, J. E., Rhee, S. Y., … Shin, D. W. (2021). Lipid Level, Lipid Variability, and Risk of Multiple Myeloma: A Nationwide Population-Based Study of 3,527,776 Subjects. Cancers (Basel), 13(3). https://doi.org/10.3390/cancers13030540
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    • Jeong, S.-M., Choi, T., Kim, D., Han, K., Kim, S. J., Rhee, S. Y., … Shin, D. W. (2020). Association between high-density lipoprotein cholesterol level and risk of hematologic malignancy. Leukemia. https://doi.org/10.1038/s41375-020-01081-5
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    • Smith, P., Thompson, J. C., Perea, E., Wasserman, B., Bohannon, L., Racioppi, A., … Sung, A. D. (2020). Clinical and Neuroimaging Correlates of Post-Transplant Delirium. Biol Blood Marrow Transplant, 26(12), 2323–2328. https://doi.org/10.1016/j.bbmt.2020.09.016
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    • Maung, K., Ramalingam, S., Chaudhry, M., Ren, Y., Jung, S.-H., Romero, K., … Sung, A. D. (2020). Pre-transplant hepatic steatosis (fatty liver) is associated with chronic graft-vs-host disease but not mortality. Plos One, 15(9), e0238824. https://doi.org/10.1371/journal.pone.0238824
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    • Choi, T. (2019). Is autologous stem cell transplantation still relevant for multiple myeloma? Curr Opin Hematol, 26(6), 386–391. https://doi.org/10.1097/MOH.0000000000000538
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    • Diwakar, D., Choi, T., Tawbi, T. H., & Kirkwood, J. M. (2014). RE: Differential influence of vemurafenib and dabrafenib on patients' lymphocytes despite similar clinical efficacy in melanoma. Annals of Oncology, 25(8), 1670–1671. https://doi.org/10.1093/annonc/mdu196
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    • Choi, T., Ferris, S. T., Matsumoto, N., Poursine-Laurent, J., & Yokoyama, W. M. (2011). Ly49-Dependent NK Cell Licensing and Effector Inhibition Involve the Same Interaction Site on MHC Ligands. The Journal of Immunology, 186(7), 3911–3917. https://doi.org/10.4049/jimmunol.1004168
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    • Yoo, J. H., Jang, S. A., & Choi, T. (2010). Sociocultural Determinants of Negative Emotions Among Dementia Caregivers in the United States and in Korea: A Content Analysis of Online Support Groups. Howard Journal of Communications, 21(1), 1–19. https://doi.org/10.1080/10646170903501195
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    • Kim, S., Sunwoo, J. B., Yang, L., Choi, T., Song, Y.-J., French, A. R., … Yokoyama, W. M. (2008). HLA alleles determine differences in human natural killer cell responsiveness and potency. Proceedings of the National Academy of Sciences, 105(8), 3053–3058. https://doi.org/10.1073/pnas.0712229105
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  • Conference Papers

    • Maung, K., An Chao, N. J., Corbet, K., Engemann, A. M., Gasparetto, C., Horwitz, M., … Choi, T. (2020). CLO20-049: Retrospective Study of Safety and Toxicity Profile Comparison for Propylene Glycol-Free Melphalan (Evomela®) and Generic Melphalan. In Journal of the National Comprehensive Cancer Network (Vol. 18, pp. CLO20-049). Harborside Press, LLC. https://doi.org/10.6004/jnccn.2019.7412
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    • Ramalingam, S., Siamakpour-Reihani, S., Bohannon, L., Ren, Y., Sibley, A., Nixon, A., … Sung, A. D. (2020). Phase II Trial of Pasireotide to Prevent GI Toxicity and Acute Gvhd in Allogeneic HSCT. In Biology of Blood and Marrow Transplantation (Vol. 26, pp. S48–S49). Orlando, FL: ELSEVIER SCIENCE INC.
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    • Smith, P. J., Lew, M., Lowder, Y. P., Romero, K., Thompson, J., Bohannen, L., … Sung, A. D. (2020). Cognitive Impairment in Candidates for Allogeneic Hematopoietic Stem Cell Transplantation. In Biology of Blood and Marrow Transplantation (Vol. 26, pp. S241–S241). Orlando, FL: ELSEVIER SCIENCE INC.
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    • Bohannon, L. M., Page, K. M., Ren, Y., Jung, S.-H., Giri, V. K., Lew, M. V., … Sung, A. D. (2019). Decreased Mortality after the First Year of Allogeneic Hematopoietic Stem Cell Transplant in Recipients of Umbilical Cord Blood Vs. Matched Related or Matched Unrelated Donors. In Blood (Vol. 134, pp. 4613–4613). American Society of Hematology. https://doi.org/10.1182/blood-2019-126906
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    • Giri, V. K., Kegerreis, K. G., Ren, Y., Bohannon, L. M., Lobaugh-Jin, E., Messina, J. A., … Sung, A. D. (2019). Daily Chlorhexidine Gluconate Bathing Reduces the Rate of Bloodstream Infections in Adults Undergoing Inpatient Hematopoietic Stem Cell Transplantation. In Blood (Vol. 134, pp. 2210–2210). American Society of Hematology. https://doi.org/10.1182/blood-2019-122272
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    • Lew, M. V., Ren, Y., Lowder, Y. P., Romero, K. M., Thompson, J. C., Bohannon, L. M., … Sung, A. D. (2019). Geriatric Assessment Identifies Impairments in Younger Candidates for Allogeneic Hematopoietic Stem Cell Transplantation. In Blood (Vol. 134, pp. 1984–1984). American Society of Hematology. https://doi.org/10.1182/blood-2019-127264
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    • Maung, K. K. K., Chaudhry, M., Ren, Y., Jung, S.-H., Romero, K. M., Corbet, K., … Sung, A. D. (2019). Pre-Transplant Hepatic Steatosis (fatty liver) Predicts Chronic Graft-Vs-Host Disease but Does Not Affect Mortality. In Blood (Vol. 134, pp. 5731–5731). American Society of Hematology. https://doi.org/10.1182/blood-2019-121830
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    • Choi, T., Kodali, M. K., & Weng, W.-K. (2017). Hematopoietic Cell Transplantation Provides Durable Disease Control in Patients with Double-Hit Lymphoma. In Biology of Blood and Marrow Transplantation (Vol. 23, pp. S263–S264). Elsevier BV. https://doi.org/10.1016/j.bbmt.2016.12.426
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    • Choi, T., Poursine‐Laurent, J., Matsumoto, N., & Yokoyama, W. (2008). Interaction sites on H2Dd for Ly49A‐dependent natural killer (NK) cell licensing. In The Faseb Journal (Vol. 22, pp. 672.37-672.37). San Diego, CA, USA: Federation of American Society of Experimental Biology. https://doi.org/10.1096/fasebj.22.1_supplement.672.37
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