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Aatif Mairaj Husain

Professor of Neurology
Neurology, Epilepsy and Sleep
Duke Box 2720, Duke University Medical Center, Durham, NC 27710
2424 Erwin Road, Suite 1001, Office 10021, Durham, NC 27705

Current Appointments & Affiliations


Professor of Neurology · 2012 - Present Neurology, Epilepsy and Sleep, Neurology
Director of Neurodiagnostic Lab / EP-IOM Lab in the Department of Neurology · 2006 - Present Neurology, Clinical Science Departments
Division Chief, Epilepsy, Sleep, and Neurophysiology in the Department of Neurology · 2018 - Present Neurology, Clinical Science Departments
Director of Operations, Capacity, and Communication in the Department of Neurology · 2022 - Present Neurology, Clinical Science Departments
Member in the Duke Clinical Research Institute · 2017 - Present Duke Clinical Research Institute, Institutes and Centers

Recent Publications


Responsive neurostimulation detections: "Recognizing the unseen".

Journal Article Epileptic Disord · May 24, 2025 BACKGROUND: Closed-loop responsive neurostimulation (RNS) is an established non-resective neuromodulatory therapy for individuals with drug-resistant epilepsy (DRE). RNS systems are typically programmed to detect and respond to predefined seizure onset pat ... Full text Link to item Cite

Of Pilots and Copilots: The Evolving Role of Artificial Intelligence in Clinical Neurophysiology.

Journal Article Neurodiagn J · March 2025 Artificial intelligence (AI) is revolutionizing clinical neurophysiology (CNP), particularly in its applications to electroencephalography (EEG), electromyography (EMG), and polysomnography (PSG). AI enhances diagnostic accuracy and efficiency while addres ... Full text Link to item Cite

Resolving a "W-Shaped" P100 Waveform: Is It Normal or Abnormal?

Journal Article J Clin Neurophysiol · January 1, 2025 Pattern-reversal visual evoked potentials are used to assess the visual pathways. The main waveform of interest is the P100, which is best recorded with electrodes over the mid-occipital region. Most often, the P100 waveform has negative-positive-negative ... Full text Link to item Cite
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Recent Grants


A Multicenter, Open-label, Long-term, Safety, Tolerability, and Efficacy Study of XEN1101 in Adults Diagnosed With Epilepsy

Clinical TrialPrincipal Investigator · Awarded by Xenon Pharmaceuticals Inc. · 2023 - 2028

The overlap of speech production and verbal working memory

ResearchCo Investigator · Awarded by National Institute of Neurological Disorders and Stroke · 2023 - 2028

Promoting Effective Self-Management of Chronic Pain with mHealth Neurofeedback

ResearchCo Investigator · Awarded by National Institutes of Health · 2022 - 2027

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Education, Training & Certifications


Rawalpindi Medical College (India) · 1989 M.B.B.S.