Journal ArticleAnesth Analg · March 1, 2023
BACKGROUND: The efficacy of postoperative nausea and vomiting (PONV) prevention protocols in low-income countries is not well known. Different surgical procedures, available medications, and co-occurring diseases imply that existing protocols may need vali ...
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Journal ArticlePLoS One · 2022
In Ghana, the high-risk obstetric referral system is inadequate. Delay is common and patients often arrive to receiving hospitals in compromised states. An effective referral system should include an adequately resourced referral hospital, communication ac ...
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Journal ArticleObstet Gynecol · October 1, 2021
OBJECTIVE: To assess the causes of maternal mortality at a referral hospital in Rwanda. METHODS: A secondary data analysis of 217 women with recorded maternal mortality from 2017 to 2019 was conducted among 11,308 total maternal admissions. Demographics, d ...
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Journal ArticlePan African Medical Journal One Health · January 1, 2021
Introduction: the World Health Organization recommends exclusive breastfeeding for the first six months of life. Over 85% of infants are exclusively breastfed in Rwanda, with nearly 20% of them being stunted by this age. This suggests nutritional issues st ...
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Journal ArticleA A Pract · July 2020
Dural puncture following neuraxial anesthesia can cause persistent cerebrospinal fluid leakage. A 35-year-old, 39-week gestation healthy parturient underwent cesarean delivery under spinal anesthesia. Spinal anesthesia was performed using a 25-gauge Quinck ...
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Journal ArticleA A Pract · September 15, 2019
A term baby was delivered by cesarean and found to have an unexpected large teratoma attached to its mouth. Surgical excision was planned within 24 hours. Anesthesia concern of airway control required multidisciplinary team consultation, airway and patient ...
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Journal ArticleBMC Med Educ · February 11, 2019
BACKGROUND: Frontline healthcare workers are critical to meeting the maternal, newborn and child health Sustainable Development Goals in low- and middle-income countries. The World Health Organization has identified leadership development as integral to ac ...
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Journal ArticleBMC Health Serv Res · January 25, 2019
BACKGROUND: There is little information about the current management of pain after obstetric surgery at Mulago hospital in Uganda, one of the largest hospitals in Africa with approximately 32,000 deliveries per year. The primary goal of this study was to a ...
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Journal ArticleMidwifery · June 2018
OBJECTIVE: to introduce and embed a midwife-led obstetric triage system in a busy labour ward in Accra, Ghana to improve the quality of care and to reduce delay. DESIGN: the study utilized a participatory action research design. Local staff participated in ...
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Journal ArticleBMJ Global Health · March 1, 2018
Institutional delivery has been proposed as a method for reducing maternal morbidity and mortality, but little is known about how referral hospitals in low-resource settings can best manage the expected influx of patients. In this study, we assess the impa ...
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Journal ArticleBMC Pregnancy Childbirth · July 11, 2017
BACKGROUND: Delay in receiving care significantly contributes to maternal morbidity and mortality. Much has been studied about reducing delays prior to arrival to referral facilities, but the delays incurred upon arrival to the hospital have not been descr ...
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Journal ArticleFront Public Health · 2017
Ghana, like other countries in sub-Saharan African, has limited access to surgery. One contributing factor is the inadequate number of anesthesia providers. To address this need, Kybele, Inc., a US-based non-governmental organization, partnered with the Gh ...
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Journal ArticlePLoS One · 2017
OBJECTIVE: To evaluate the cost-effectiveness of a quality improvement intervention aimed at reducing maternal and fetal mortality in Accra, Ghana. DESIGN: Quasi-experimental, time-sequence intervention, retrospective cost-effectiveness analysis. METHODS: ...
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Journal ArticleFront Public Health · 2017
INTRODUCTION: Postpartum hemorrhage (PPH) remains a global challenge, affecting thirteen million women each year. In addition, PPH is a leading cause of maternal mortality in Asia and Africa. In the U.S.A., care of critically ill patients is often practice ...
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Journal ArticleAnaesthesia · September 2016
There are few data regarding postoperative hyperglycaemia in non-diabetic compared with diabetic patients following postoperative nausea and vomiting prophylaxis with dexamethasone. Eighty-five non-diabetic patients and patients with type-2 diabetes were r ...
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Journal ArticleJ Clin Anesth · August 2016
We report the use of rotational thromboelastometry (ROTEM) to guide the management of a 29-year-old primigravida at 36weeks' gestation with portal hypertension, esophageal varices, suspected pseudocholinesterase deficiency, and steroid refractory thrombocy ...
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Journal ArticleInt J Gynaecol Obstet · August 2016
OBJECTIVE: To evaluate the performance of a continuous quality improvement collaboration at Ridge Regional Hospital, Accra, Ghana, that aimed to halve maternal and neonatal deaths. METHODS: In a quasi-experimental, pre- and post-intervention analysis, syst ...
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Journal ArticleInt J Obstet Anesth · May 2016
We present a case of accidental injection of tranexamic acid during spinal anesthesia for an elective cesarean delivery. Immediately following intrathecal injection of 2mL of solution, the patient complained of severe back pain, followed by muscle spasm an ...
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Journal ArticleInt J Obstet Anesth · May 2016
BACKGROUND: There are limited data about spinal dosing for cesarean delivery in preterm parturients. We investigated the hypothesis that preterm gestation is associated with an increased incidence of inadequate spinal anesthesia for cesarean delivery compa ...
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Journal ArticleAnesth Analg · March 1, 2023
BACKGROUND: The efficacy of postoperative nausea and vomiting (PONV) prevention protocols in low-income countries is not well known. Different surgical procedures, available medications, and co-occurring diseases imply that existing protocols may need vali ...
Full textLink to itemCite
Journal ArticlePLoS One · 2022
In Ghana, the high-risk obstetric referral system is inadequate. Delay is common and patients often arrive to receiving hospitals in compromised states. An effective referral system should include an adequately resourced referral hospital, communication ac ...
Full textLink to itemCite
Journal ArticleObstet Gynecol · October 1, 2021
OBJECTIVE: To assess the causes of maternal mortality at a referral hospital in Rwanda. METHODS: A secondary data analysis of 217 women with recorded maternal mortality from 2017 to 2019 was conducted among 11,308 total maternal admissions. Demographics, d ...
Full textLink to itemCite
Journal ArticlePan African Medical Journal One Health · January 1, 2021
Introduction: the World Health Organization recommends exclusive breastfeeding for the first six months of life. Over 85% of infants are exclusively breastfed in Rwanda, with nearly 20% of them being stunted by this age. This suggests nutritional issues st ...
Full textCite
Journal ArticleA A Pract · July 2020
Dural puncture following neuraxial anesthesia can cause persistent cerebrospinal fluid leakage. A 35-year-old, 39-week gestation healthy parturient underwent cesarean delivery under spinal anesthesia. Spinal anesthesia was performed using a 25-gauge Quinck ...
Full textLink to itemCite
Journal ArticleA A Pract · September 15, 2019
A term baby was delivered by cesarean and found to have an unexpected large teratoma attached to its mouth. Surgical excision was planned within 24 hours. Anesthesia concern of airway control required multidisciplinary team consultation, airway and patient ...
Full textLink to itemCite
Journal ArticleBMC Med Educ · February 11, 2019
BACKGROUND: Frontline healthcare workers are critical to meeting the maternal, newborn and child health Sustainable Development Goals in low- and middle-income countries. The World Health Organization has identified leadership development as integral to ac ...
Full textLink to itemCite
Journal ArticleBMC Health Serv Res · January 25, 2019
BACKGROUND: There is little information about the current management of pain after obstetric surgery at Mulago hospital in Uganda, one of the largest hospitals in Africa with approximately 32,000 deliveries per year. The primary goal of this study was to a ...
Full textLink to itemCite
Journal ArticleMidwifery · June 2018
OBJECTIVE: to introduce and embed a midwife-led obstetric triage system in a busy labour ward in Accra, Ghana to improve the quality of care and to reduce delay. DESIGN: the study utilized a participatory action research design. Local staff participated in ...
Full textLink to itemCite
Journal ArticleBMJ Global Health · March 1, 2018
Institutional delivery has been proposed as a method for reducing maternal morbidity and mortality, but little is known about how referral hospitals in low-resource settings can best manage the expected influx of patients. In this study, we assess the impa ...
Full textCite
Journal ArticleBMC Pregnancy Childbirth · July 11, 2017
BACKGROUND: Delay in receiving care significantly contributes to maternal morbidity and mortality. Much has been studied about reducing delays prior to arrival to referral facilities, but the delays incurred upon arrival to the hospital have not been descr ...
Full textLink to itemCite
Journal ArticleFront Public Health · 2017
Ghana, like other countries in sub-Saharan African, has limited access to surgery. One contributing factor is the inadequate number of anesthesia providers. To address this need, Kybele, Inc., a US-based non-governmental organization, partnered with the Gh ...
Full textOpen AccessLink to itemCite
Journal ArticlePLoS One · 2017
OBJECTIVE: To evaluate the cost-effectiveness of a quality improvement intervention aimed at reducing maternal and fetal mortality in Accra, Ghana. DESIGN: Quasi-experimental, time-sequence intervention, retrospective cost-effectiveness analysis. METHODS: ...
Full textLink to itemCite
Journal ArticleFront Public Health · 2017
INTRODUCTION: Postpartum hemorrhage (PPH) remains a global challenge, affecting thirteen million women each year. In addition, PPH is a leading cause of maternal mortality in Asia and Africa. In the U.S.A., care of critically ill patients is often practice ...
Full textLink to itemCite
Journal ArticleAnaesthesia · September 2016
There are few data regarding postoperative hyperglycaemia in non-diabetic compared with diabetic patients following postoperative nausea and vomiting prophylaxis with dexamethasone. Eighty-five non-diabetic patients and patients with type-2 diabetes were r ...
Full textLink to itemCite
Journal ArticleJ Clin Anesth · August 2016
We report the use of rotational thromboelastometry (ROTEM) to guide the management of a 29-year-old primigravida at 36weeks' gestation with portal hypertension, esophageal varices, suspected pseudocholinesterase deficiency, and steroid refractory thrombocy ...
Full textLink to itemCite
Journal ArticleInt J Gynaecol Obstet · August 2016
OBJECTIVE: To evaluate the performance of a continuous quality improvement collaboration at Ridge Regional Hospital, Accra, Ghana, that aimed to halve maternal and neonatal deaths. METHODS: In a quasi-experimental, pre- and post-intervention analysis, syst ...
Full textOpen AccessLink to itemCite
Journal ArticleInt J Obstet Anesth · May 2016
We present a case of accidental injection of tranexamic acid during spinal anesthesia for an elective cesarean delivery. Immediately following intrathecal injection of 2mL of solution, the patient complained of severe back pain, followed by muscle spasm an ...
Full textLink to itemCite
Journal ArticleInt J Obstet Anesth · May 2016
BACKGROUND: There are limited data about spinal dosing for cesarean delivery in preterm parturients. We investigated the hypothesis that preterm gestation is associated with an increased incidence of inadequate spinal anesthesia for cesarean delivery compa ...
Full textOpen AccessLink to itemCite
Journal ArticleMiddle East J Anaesthesiol · February 2016
BACKGROUND: The unimodal approach of using pentazocine as post-cesarean section pain relief is inadequate, hence the need for a safer, easily available and more effective multimodal approach. AIM: To evaluate the effectiveness of rectal diclofenac combined ...
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Journal ArticleJ Obstet Gynaecol Can · October 2015
OBJECTIVE: In Ghana, regional referral facilities by design receive a disproportionate number of high-risk obstetric and neonatal cases and therefore have mortality rates higher than the national average. High volumes and case complexity result in these fa ...
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Journal ArticleAnesth Analg · June 2015
Featured Publication
Anesthesia providers in low-income countries may infrequently provide regional anesthesia techniques for obstetrics due to insufficient training and supplies, limited manpower, and a lack of perceived need. In 2007, Kybele, Inc. began a 5-year collaboratio ...
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Journal ArticleSouthern African Journal of Anaesthesia and Analgesia · January 1, 2015
Background: While epidural analgesia for labour pain is standard in high-resource countries, minimal to no analgesia is usually provided in low-resource countries. Intrathecal local anaesthetics provide good pain relief, but the potential impact on ambulat ...
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Journal ArticleInt J Gynaecol Obstet · January 2012
Featured Publication
OBJECTIVE: To reduce maternal and neonatal death at a large regional hospital through the use of quality improvement methodologies. METHODS: In 2007, Kybele and the Ghana Health Service formed a partnership to analyze systems and patient care processes at ...
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Journal ArticleCurr Med Res Opin · November 2011
OBJECTIVE: To assess the impact of intraoperative dexmedetomidine infusion on postoperative analgesia in women undergoing major open and laparoscopic gynecologic surgery under general anesthesia. RESEARCH DESIGN AND METHODS: A retrospective analysis of pat ...
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Journal ArticleInt J Obstet Anesth · October 2010
BACKGROUND: Ropivacaine may be the ideal spinal anesthetic for postpartum tubal ligation due to its medium duration of action, low incidence of side effects and possibly reduced post-anesthetic care unit (PACU) stay. METHODS: Two prospective up-down sequen ...
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Journal ArticleAnesth Analg · February 2008
Featured Publication
The Episure AutoDetect syringe, a spring-loaded syringe, is a new loss-of-resistance syringe with an internal compression spring that applies constant pressure on the plunger. In this pilot study, we compared the spring-loaded syringe with the standard gla ...
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Journal ArticleCan J Anaesth · August 2007
PURPOSE: To describe the anesthetic and peripartum management of a parturient with paroxysmal nocturnal hemoglobinuria complicated by severe preeclampsia, review the pathophysiology of this condition, rationale for thromboembolic prophylaxis, and its impli ...
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Journal ArticleAmbulatory Surgery · March 1, 2007
Purpose: To test the hypothesis that using remifentanil during nitrous oxide-sevoflurane anesthetic would be associated with less postoperative nausea and vomiting (PONV) compared to a similar technique with fentanyl. Scope: Sixty patients undergoing outpa ...
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Journal ArticleBr J Anaesth · May 2006
We present a case of torsion dystonia in a 35-yr-old primigravida who presented for a Caesarean section under general anaesthesia. She had limb contractures and severe kyphoscoliosis associated with limited respiratory reserve and function. General anaesth ...
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Journal ArticleEur J Anaesthesiol · April 2006
BACKGROUND AND OBJECTIVE: We compared the dose requirement and side effect profile of total intravenous anaesthesia using Diprivan to generic propofol at a specific anaesthetic target level utilizing the bispectral index monitor to determine efficacy diffe ...
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Journal ArticleAnesth Analg · February 2006
We randomized 94 patients undergoing cesarean delivery with spinal anesthesia to receive transcutaneous acupoint electrical stimulation using the ReliefBand at the P6 point (active group) or an active ReliefBand applied to the dorsum of the wrist (sham con ...
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Journal ArticleJ Clin Anesth · February 2005
STUDY OBJECTIVES: To compare the effectiveness of treating established postoperative nausea and vomiting (PONV) with an antiemetic acting at a different receptor with that of treating PONV with the antiemetic used for prophylaxis. DESIGN: Analysis of data ...
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Journal ArticleAnesth Analg · January 2005
Postpartum bilateral tubal ligation (PPBTL) causes postoperative pain. We designed this study to determine the efficacy of 50 microg intrathecal morphine for analgesia after PPBTL. Sixty-five women received spinal anesthesia with 12.75 mg hyperbaric bupiva ...
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Journal ArticleAnaesthesia · November 2004
Changes in the tracheal tube tip to carina distance were measured by radiographic screening following various head postures in 45 children undergoing cardiac catheterisation under general anaesthesia who were intubated via nasal and oral routes. Extension ...
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Journal ArticleBr J Anaesth · October 2002
We describe a case of a 36-yr-old patient who presented at 14 weeks gestation with multifocal dysrrhythmic episodes. Despite treatment with anti-arrythmic agents and an implantable cardioverter defibrillator (ICD) in situ, she continued to experience persi ...
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Journal ArticleCan J Anaesth · 2002
Featured Publication
PURPOSE: To examine if ilioinguinal-iliohypogastric nerve block could reduce the need for post-Cesarean delivery morphine analgesia and thus reduce the incidence of opioid related adverse-effects. METHODS: A multi-level technique for performing the nerve b ...
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Journal ArticleAnesth Analg · September 2000
In this preliminary investigation, we evaluated the safety and analgesic efficacy of IV remifentanil for labor pain. Four women were studied, and then the trial was terminated because administration of this novel synthetic opioid produced significant mater ...
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Journal ArticleAnesthesiology · August 2000
BACKGROUND: The combined spinal-epidural (CSE) technique using bupivicaine-fentanyl has become an established method of pain control during parturition. One limitation is the relatively short duration of effective analgesia produced by bupivicaine-fentanyl ...
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Journal ArticleAnaesthesia · November 1999
Sixty ASA physical status I and II, premedicated patients were administered propofol 2 mg x kg-1 and remifentanil 2 microg x kg-1 (group R), alfentanil 50 microg x kg-1 (group A) or suxamethonium 1 mg x kg-1 (group S) as a rapid bolus. One minute after stu ...
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Journal ArticleAnaesthesia · November 1999
Sixty ASA I and II patients, premedicated with midazolam, were administered propofol 2 mg x kg-1 and remifentanil 3 microg x kg-1 (group R3), remifentanil 4 microg x kg-1 (group R4) and remifentanil 5 microg x kg-1 (group R5). Laryngoscopy and intubation w ...
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