Overview
I am interested in developing approaches to derive biological insight from multi-omics and biological "big" data. My areas of research include metabolic diseases like atypical diabetes, exercise, and calorie restriction. In addition to my research program, I also teach an undergraduate course called "Digital Intelligence" (https://scholars.duke.edu/course/SCISOC256) which introduces students to ethical, social, and technical aspects of emerging technologies like so-called "AI". Finally, I run an annual Ph.D. Computational Summer Fellowship through the Center for Computational Thinking (https://computationalthinking.duke.edu/phd-computational-fellowship/).
Current Appointments & Affiliations
Assistant Professor of Medicine
·
2021 - Present
Medicine, Endocrinology, Metabolism, and Nutrition,
Medicine
Member of Duke Molecular Physiology Institute
·
2021 - Present
Duke Molecular Physiology Institute,
Institutes and Centers
Recent Publications
Biological Mechanisms of Strength Preservation During Calorie Restriction-Induced Weight Loss Among Young- to Middle-Aged Adults without Obesity.
Preprint · January 30, 2026 Full text Link to item CiteNeutralizing hepatic apolipoprotein E enhances aged bone fracture healing.
Journal Article Bone Res · January 22, 2026 Advanced age impairs bone fracture healing; the underlying mechanism of this phenomenon remains unknown. We determined that apolipoprotein E (ApoE) increases with age and causes poor fracture healing. After deletion of hepatic ApoE expression (ΔApoE), 24-m ... Full text Link to item CiteCysteine S-acetylation is a widespread post-translational modification on metabolic proteins
Journal Article Npj Metabolic Health and Disease · December 1, 2025 Protein acetylation is a fundamental regulatory mechanism occurring primarily on lysine amino acids. Here we report systematic in vivo characterization of cysteine S-acetylation as a widespread post-translational modification in mammalian tissues. By devel ... Full text CiteRecent Grants
RARE and Atypical Diabetes Network (RADIANT)
ResearchInvestigator · Awarded by Baylor College of Medicine · 2018 - 2027Correction of Immune Response Improves Aged Fracture Healing
ResearchResearch Associate · Awarded by National Institutes of Health · 2020 - 2023Sfrp2 and Cardiac Progenitor Cells in Regenerative Response to Ischemic Injury
ResearchResearch Associate · Awarded by National Institutes of Health · 2005 - 2016View All Grants
Education
University of Oxford (United Kingdom) ·
2011
D.Phil.