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Alberto Bartesaghi

Associate Professor of Computer Science
Computer Science
308 Research Drive, LSRC D338, Durham, NC 27708-0129

Research Interests


Image analysis, data science, computer vision, machine learning, image reconstruction, cryo-electron microscopy, protein structure

Selected Grants


Structural and Functional Analysis of Nucleocytoplasmic Protein O-Glycosyltransferases in Plants

ResearchCollaborator · Awarded by National Institute of General Medical Sciences · 2023 - 2027

Mechanisms of LRRK2 Mediated Neurotoxicity

ResearchCollaborating Investigator · Awarded by National Institutes of Health · 2018 - 2026

Mechanistic Insights into the Plant Disease Resistance Mediated by NPR1

ResearchCo Investigator · Awarded by National Institute of General Medical Sciences · 2022 - 2026

Molecular elucidation of the Francisella tularensis virulence mechanism

ResearchCo Investigator · Awarded by National Institutes of Health · 2021 - 2026

CC* Data Storage - Flexible Affordable Scalable Technology for Research Storage - FAST-Research Storage

ResearchCo-Principal Investigator · Awarded by National Science Foundation · 2022 - 2025

Structural and Functional Analysis of Nucleocytoplasmic Protein O-Glycosyltransferases in Plants

ResearchCollaborator · Awarded by National Institute of General Medical Sciences · 2023 - 2027

Mechanisms of LRRK2 Mediated Neurotoxicity

ResearchCollaborating Investigator · Awarded by National Institutes of Health · 2018 - 2026

Mechanistic Insights into the Plant Disease Resistance Mediated by NPR1

ResearchCo Investigator · Awarded by National Institute of General Medical Sciences · 2022 - 2026

Molecular elucidation of the Francisella tularensis virulence mechanism

ResearchCo Investigator · Awarded by National Institutes of Health · 2021 - 2026

CC* Data Storage - Flexible Affordable Scalable Technology for Research Storage - FAST-Research Storage

ResearchCo-Principal Investigator · Awarded by National Science Foundation · 2022 - 2025

A Hybrid Computational Platform for High-resolution Structure Determination Using Cryo-EM

ResearchPrincipal Investigator · Awarded by National Institute of General Medical Sciences · 2021 - 2025

Multi-task learning to map proteins inside cells at near-atomic resolution

ResearchPrincipal Investigator · Awarded by Chan Zuckerberg Initiative · 2021 - 2025

Structural characterization of HIV-1 fusion using time resolved cryo-electron tomography (TR-cryo-ET)

ResearchPrincipal Investigator · Awarded by National Institute of Environmental Health Sciences · 2021 - 2022

Structural studies of virulence activation in Francisella tularensis

FellowshipCollaborator · Awarded by National Institutes of Health · 2020 - 2022

Cryo-EM Investigation of Protein Structures

ResearchPrincipal Investigator · Awarded by Syngenta Corp Protection, LLC · 2021 - 2022

Structural Elucidation of the Novel RNA Polymerase Underlying Francisella Tularensis Virulence

ResearchCollaborating Investigator · Awarded by National Institutes of Health · 2020 - 2022

Bioinformatics and Computational Biology Training Program

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2005 - 2021

Structural Analysis of Env During HIV-1 Maturation Using In-situ Cryo-electron Tomography

ResearchPrincipal Investigator · Awarded by National Institute of Environmental Health Sciences · 2019 - 2020