Skip to main content

Barbara Dudley Alexander

Professor of Medicine
Medicine, Infectious Diseases
Duke Box 102359, Durham, NC 27710
315 Trent Drive, Hanes House, Room 163A, Durham, NC 27710

Overview


Clinical research related to infectious complications of solid organ and bone marrow transplantation, with a particular interest in the treatment and rapid diagnosis of fungal disease. Training the next generation of Transplant Infectious Disease Physicians is a special focus of mine as the Principal Investigator of our Interdisciplinary T32 Training Program funded the NIH.

Current Appointments & Affiliations


Professor of Medicine · 2014 - Present Medicine, Infectious Diseases, Medicine
Professor of Pathology · 2014 - Present Pathology, Clinical Science Departments

Recent Publications


Epidemiology of Healthcare Facility-Associated Nontuberculous Mycobacteria From 2012 Through 2020 in a 10-Hospital Network in the United States.

Journal Article Clin Infect Dis · February 4, 2026 BACKGROUND: Data on the epidemiology of healthcare facility-associated (HCFA) nontuberculous mycobacteria (NTM) are sparse. We performed a multicenter longitudinal cohort study of HCFA NTM epidemiology. METHODS: We retrospectively analyzed positive culture ... Full text Link to item Cite

Concurrent Administration of Triazoles with Chemotherapeutic and/or Immunosuppressant Agents Known to Have Moderate-to-Severe Drug-Drug Interactions in Patients with Hematologic Malignancies Hospitalized for Invasive Aspergillosis.

Journal Article Mycopathologia · January 13, 2026 BACKGROUND: Triazoles are widely used for treatment and prevention of invasive aspergillosis (IA) but can cause serious drug-drug interactions (DDIs) with chemotherapeutic (CT) and immunosuppressant (IS) agents via CYP3A4 inhibition. The frequency of triaz ... Full text Link to item Cite

Co-administration of triazoles with calcineurin or mammalian target of rapamycin inhibitors in solid organ transplant patients hospitalized with invasive aspergillosis.

Journal Article J Antimicrob Chemother · January 6, 2026 BACKGROUND: All triazoles decrease the metabolism of calcineurin inhibitors (CNIs) and mammalian target of rapamycin (mTOR) inhibitors through CYP3A4 and P-glycoprotein inhibition leading to increased exposure and the potential for serious adverse events ( ... Full text Link to item Cite
View All Publications

Recent Grants


Novel Host-Response Biomarker Diagnostics for Invasive Aspergillosis

ResearchCo-Mentor · Awarded by National Institute of Allergy and Infectious Diseases · 2024 - 2029

Tri-Institutional Molecular Mycology and Pathogenesis Training Program

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2024 - 2029

UAB - Clinical and Applied Research Strategies for the Prevention and Control of Fungal Diseases

ResearchPrincipal Investigator · Awarded by University of Alabama at Birmingham · 2023 - 2028

View All Grants

Education, Training & Certifications


East Carolina University · 1993 M.D.