https://orcid.org/0000-0001-5868-0529
Overview
Clinical research related to infectious complications of solid organ and bone marrow transplantation, with a particular interest in the treatment and rapid diagnosis of fungal disease. Training the next generation of Transplant Infectious Disease Physicians is a special focus of mine as the Principal Investigator of our Interdisciplinary T32 Training Program funded the NIH.
Current Duke Appointments & Affiliations
Professor of Medicine
·
2014 - Present
Medicine, Infectious Diseases,
Medicine
Professor of Pathology
·
2014 - Present
Pathology,
Clinical Science Departments
Recent Scholarly Works
Organ-specific differences in the epidemiology of cytomegalovirus infections in high-risk (cytomegalovirus donor seropositive, recipient seronegative) solid organ transplant recipients with prolonged follow-up: A 10-year experience.
Journal article Am J Transplant · March 26, 2026 Cytomegalovirus (CMV) causes significant morbidity in CMV donor seropositive/recipient seronegative (D+R-) solid organ transplant recipients, but organ-specific differences in CMV epidemiology and the utility of laboratory surveillance after prophylaxis (S ... Full text Link to item CiteFungal diagnostic stewardship in immunocompromised populations: a focus on molds and dimorphic fungi.
Journal article Clin Microbiol Rev · March 12, 2026 SUMMARYInvasive fungal diseases cause severe illness and death in immunocompromised patients. Antifungal use is increasingly common, as is fungal diagnostic testing. However, these efforts have not been guided by traditional stewardship efforts akin to tho ... Full text Link to item CiteOlorofim in combination with azole antifungals: results from the Phase 2 salvage therapy study.
Journal article J Antimicrob Chemother · March 4, 2026 BACKGROUND: Olorofim is an antifungal agent with a novel mechanism of action against Aspergillus spp., rare moulds and dimorphic fungi. Preclinical studies reported unidirectional antagonism between olorofim and mould-active azoles (e.g. azoles other than ... Full text Link to item CiteRecent Grants
Novel Host-Response Biomarker Diagnostics for Invasive Aspergillosis
ResearchCo-Mentor · Awarded by National Institute of Allergy and Infectious Diseases · 2024 - 2029Tri-Institutional Molecular Mycology and Pathogenesis Training Program
Inst. Training Prgm or CMEMentor · Awarded by National Institute of Allergy and Infectious Diseases · 2024 - 2029UAB - Clinical and Applied Research Strategies for the Prevention and Control of Fungal Diseases
ResearchPrincipal Investigator · Awarded by University of Alabama at Birmingham · 2023 - 2028View All Grants
Education
East Carolina University ·
1993
M.D.