Barbara Dudley Alexander
Professor of Medicine
Clinical research related to infectious complications of solid organ and bone marrow transplantation, with a particular interest in the treatment and rapid diagnosis of fungal disease. Training the next generation of Transplant Infectious Disease Physicians is a special focus of mine as the Principal Investigator of our Interdisciplinary T32 Training Program funded the NIH.
Current Appointments & Affiliations
- Professor of Medicine, Medicine, Infectious Diseases, Medicine 2014
- Professor of Pathology, Pathology, Clinical Science Departments 2014
Contact Information
- 315 Trent Drive, Hanes House, Room 163A, Durham, NC 27710
- Duke Box 102359, Durham, NC 27710
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alexa011@mc.duke.edu
(919) 668-0789
- Background
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Education, Training, & Certifications
- Fellow, Infectious Diseases, Medicine, Duke University 1996 - 1998
- Medical Resident, Medicine, Duke University 1993 - 1996
- M.D., East Carolina University 1993
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Previous Appointments & Affiliations
- Associate Professor of Pathology, Pathology, Clinical Science Departments 2007 - 2014
- Associate Professor of Medicine, Medicine, Infectious Diseases, Medicine 2011 - 2014
- Associate Professor of Medicine, Medicine, Infectious Diseases, Medicine 2007 - 2010
- Assistant Professor of Medicine, Medicine, Infectious Diseases, Medicine 2002 - 2007
- Associate in the Department of Medicine, Medicine, Infectious Diseases, Medicine 1999 - 2002
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Leadership & Clinical Positions at Duke
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Vice Chief, Transplant Infectious Diseases
Director, Transplant ID Fellowship Program
Head, Clinical Mycology Laboratory
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- Expertise
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Subject Headings
- Research
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Selected Grants
- Targeting the B Cell Response to Treat Antibody-Mediated Rejection awarded by National Institutes of Health 2021 - 2028
- Combined Use of Statistical Process Control and Whole Genome Sequencing to Detect and Investigate Nontuberculous Mycobacterial Clusters and Outbreaks (K08) awarded by National Institutes of Health 2021 - 2026
- A Phase 3, Multicenter, Prospective, Randomized, Double-blind Study of Two Treatment Regimens for Candidemia and/or Invasive Candidiasis: Intravenous Echinocandin followed by Oral Ibrexafungerp versus Intravenous Echinocandin followed Oral Fluconanaz awarded by Scynexis Inc 2022 - 2024
- Duke CTSA (TL1) Year 5 awarded by National Institutes of Health 2018 - 2024
- Open-Label Study to Evaluate the Efficacy and Safety of SCY-078 in Patients with Invasive Fungal Infections that are Refractory to or Intolerant of Standard Antifungal Treatment (FURII) awarded by Scynexis Inc 2016 - 2023
- Transplant Infectious Diseases Interdisciplinary Research Training Grant (TIDIRTG) awarded by National Institutes of Health 2018 - 2023
- F901318 - Aspergillus awarded by F2G Ltd 2019 - 2023
- ReSTORE - A phase 3 study of the efficacy and safety of rezafungin for injection versus intravenous caspofungin followed by optional oral fluconazole step-down in the treatment of subjects with candidemia and/or invasive candidiasis awarded by Cidara Therapeutics, Inc. 2019 - 2022
- Observational Disease Registry of Patients Treated with Systemic Mold-Active Triazoles (MAT Registry) awarded by Astellas Pharma Global Development, Inc 2017 - 2022
- Scy-078-206 awarded by Scynexis Inc 2019 - 2021
- A Phase 3, multicenter, randomized, open-label, active-controlled study to assess the efficacy and safety of maribavir treatment compared to Investigator-assigned treatment in transplant recipients with cytomegalovirus (CMV) infections that are refra awarded by Shire Human Genetics Therapies 2017 - 2021
- Non-Interventional Registry Study of Systemic Antifungal Therapy in Adult Subjects with Invasive Mucormycosis or Invasive Aspergillosis Caused by a Non-fumigatus Species (PMC Registry) awarded by Astellas Pharma Global Development, Inc 2017 - 2020
- Retrospective Observational Study to Evaluate the "Real World" Effectiveness of Posaconazole Prophylaxis in Patients with Hematological Malignancies at Duke University Hospital awarded by Merck Sharp & Dohme 2017 - 2020
- Host-derived biomarker signatures to differentiate acute viral, bacterial, and fungal infection awarded by National Institutes of Health 2017 - 2020
- GS-US-218-0108 - Upper Respiratory awarded by Gilead Sciences, Inc. 2015 - 2018
- GS-US-218-1502 - Lower Respiratory awarded by Gilead Sciences, Inc. 2015 - 2018
- Scynexis - SCY7802 awarded by Scynexis Inc 2015 - 2017
- Institutional Training Grant in Pediatric Infectious Disease awarded by National Institutes of Health 2011 - 2016
- Activity of SCY - 078 (MK-3118), a new oral glucan synthase inhibitor, against clinical Candida isolates" awarded by Scynexis Inc 2014 - 2016
- Activity of VT1161 and VT1598 Against Candida Isolates Clinically Resistant to Azole and Echinocandin Antifungal Agents awarded by Viamet Pharmaceuticals 2013 - 2016
- Longitudinal assessment of CMV and BK virus immunity in renal transplant patients awarded by National Institutes of Health 2013 - 2016
- Clinical Laboratory Diagnostics for Invasive Aspergillosis awarded by University of Florida 2010 - 2015
- Mid-Career Investigator Award: Preventing and Diagnosing Fungal Disease in Transplantation awarded by National Institutes of Health 2007 - 2013
- Microfluidic PCR Platform to Detect Microbial DNA awarded by National Institutes of Health 2005 - 2010
- Prevention & dx of fungal infxns in transplantation awarded by National Institutes of Health 2002 - 2007
- Mentored Clinical Research Scholar Program awarded by National Institutes of Health 2002 - 2006
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External Relationships
- F2G Pharmaceutical Company
- HealthTracksRx
- Infectious Diseases Board Review Course
- Infectious Diseases Society of America
- Merck & Co. USA (not assoc'd with Merck KGaA)
- Mycoses Study Group Education & Research Consortium
- UpToDate, Inc
- thermofisher
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Carugati, Manuela, Sana Arif, Debra Lynn Sudan, Bradley Henry Collins, John Carroll Haney, Jacob Niall Schroder, John Michael Reynolds, et al. “Epidemiology of surgical site infections after solid organ transplants in the period 2015-2019: A single-center retrospective cohort study.” Am J Transplant 22, no. 12 (December 2022): 3021–30. https://doi.org/10.1111/ajt.17189.Full Text Open Access Copy Link to Item
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Strand, Andrew M., Barbara D. Alexander, Eric Sarpong, Jessica Retuerto Wong, Ashley Engemann, David Rizzieri, Yuan Wu, and Melissa D. Johnson. “Real-world effectiveness of antifungal prophylaxis with posaconazole as the primary agent in patients with haematological malignancies.” Mycoses 65, no. 11 (November 2022): 1050–60. https://doi.org/10.1111/myc.13495.Full Text Link to Item
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Angulo, David A., Barbara Alexander, Riina Rautemaa-Richardson, Ana Alastruey-Izquierdo, Martin Hoenigl, Ashraf S. Ibrahim, Mahmoud A. Ghannoum, Thomas R. King, Nkechi E. Azie, and Thomas J. Walsh. “Ibrexafungerp, a Novel Triterpenoid Antifungal in Development for the Treatment of Mold Infections.” J Fungi (Basel) 8, no. 11 (October 25, 2022). https://doi.org/10.3390/jof8111121.Full Text Link to Item
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Avery, Robin K., Sophie Alain, Barbara D. Alexander, Emily A. Blumberg, Roy F. Chemaly, Catherine Cordonnier, Rafael F. Duarte, et al. “Maribavir for Refractory Cytomegalovirus Infections With or Without Resistance Post-Transplant: Results From a Phase 3 Randomized Clinical Trial.” Clin Infect Dis 75, no. 4 (September 10, 2022): 690–701. https://doi.org/10.1093/cid/ciab988.Full Text Open Access Copy Link to Item
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Ostrosky-Zeichner, L., M. H. Nguyen, J. Bubalo, B. D. Alexander, M. H. Miceli, P. G. Pappas, J. Jiang, Y. Song, and G. R. Thompson. “Multicenter Registry of Patients Receiving Systemic Mold-Active Triazoles for the Management of Invasive Fungal Infections.” Infect Dis Ther 11, no. 4 (August 2022): 1609–29. https://doi.org/10.1007/s40121-022-00661-5.Full Text Open Access Copy Link to Item
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Huggins, Jonathan P., Robert Pease, Kelly Stanly, Adrienne Workman, John Reynolds, and Barbara D. Alexander. “Safety of Inhaled Amphotericin B Lipid Complex as Antifungal Prophylaxis in Lung Transplant Recipients.” Antimicrob Agents Chemother 66, no. 6 (June 21, 2022): e0028322. https://doi.org/10.1128/aac.00283-22.Full Text Link to Item
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Heldman, Madeleine R., Olivia S. Kates, Kassem Safa, Camille N. Kotton, Ashrit Multani, Sarah J. Georgia, Julie M. Steinbrink, et al. “Delayed mortality among solid organ transplant recipients hospitalized for COVID-19.” Clin Infect Dis, February 25, 2022. https://doi.org/10.1093/cid/ciac159.Full Text Open Access Copy Link to Item
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Heldman, Madeleine R., Olivia S. Kates, Kassem Safa, Camille N. Kotton, Sarah J. Georgia, Julie M. Steinbrink, Barbara D. Alexander, et al. “Changing trends in mortality among solid organ transplant recipients hospitalized for COVID-19 during the course of the pandemic.” Am J Transplant 22, no. 1 (January 2022): 279–88. https://doi.org/10.1111/ajt.16840.Full Text Open Access Copy Link to Item
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Narayanasamy, Shanti, Adam R. Williams, Wiley A. Schell, Rebekah W. Moehring, Barbara D. Alexander, Thuy Le, Ramesh A. Bharadwaj, Michelle McGauvran, Jacob N. Schroder, and John R. Perfect. “Curvularia alcornii Aortic Pseudoaneurysm Following Aortic Valve Replacement: Case Report and Review of the Literature.” Open Forum Infect Dis 8, no. 11 (November 2021): ofab536. https://doi.org/10.1093/ofid/ofab536.Full Text Open Access Copy Link to Item
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Wingard, John R., Barbara D. Alexander, Lindsey R. Baden, Min Chen, Michele W. Sugrue, Helen L. Leather, Angela M. Caliendo, et al. “Impact of Changes of the 2020 Consensus Definitions of Invasive Aspergillosis on Clinical Trial Design: Unintended Consequences for Prevention Trials?” Open Forum Infect Dis 8, no. 10 (October 2021): ofab441. https://doi.org/10.1093/ofid/ofab441.Full Text Open Access Copy Link to Item
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Heldman, Madeleine R., Olivia S. Kates, Kassem Safa, Camille N. Kotton, Sarah J. Georgia, Julie M. Steinbrink, Barbara D. Alexander, et al. “COVID-19 in hospitalized lung and non-lung solid organ transplant recipients: A comparative analysis from a multicenter study.” Am J Transplant 21, no. 8 (August 2021): 2774–84. https://doi.org/10.1111/ajt.16692.Full Text Link to Item
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Steinbrink, Julie M., Rachel A. Myers, Kaiyuan Hua, Melissa D. Johnson, Jessica L. Seidelman, Ephraim L. Tsalik, Ricardo Henao, et al. “The host transcriptional response to Candidemia is dominated by neutrophil activation and heme biosynthesis and supports novel diagnostic approaches.” Genome Med 13, no. 1 (July 5, 2021): 108. https://doi.org/10.1186/s13073-021-00924-9.Full Text Open Access Copy Link to Item
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Eichenberger, Emily M., Felicia Ruffin, Michael Dagher, Reginald Lerebours, Sin-Ho Jung, Batu Sharma-Kuinkel, Andrew N. Macintyre, et al. “Bacteremia in solid organ transplant recipients as compared to immunocompetent patients: Acute phase cytokines and outcomes in a prospective, matched cohort study.” Am J Transplant 21, no. 6 (June 2021): 2113–22. https://doi.org/10.1111/ajt.16388.Full Text Open Access Copy Link to Item
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Dworetz, April R., Girija Natarajan, John Langer, Kathy Kinlaw, Jennifer R. James, Margarita Bidegain, Abhik Das, et al. “Withholding or withdrawing life-sustaining treatment in extremely low gestational age neonates.” Arch Dis Child Fetal Neonatal Ed 106, no. 3 (May 2021): 238–43. https://doi.org/10.1136/archdischild-2020-318855.Full Text Link to Item
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Baker, Arthur W., Eileen K. Maziarz, Sarah S. Lewis, Jason E. Stout, Deverick J. Anderson, Peter K. Smith, Jacob N. Schroder, et al. “Invasive Mycobacterium abscessus Complex Infection After Cardiac Surgery: Epidemiology, Management, and Clinical Outcomes.” Clin Infect Dis 72, no. 7 (April 8, 2021): 1232–40. https://doi.org/10.1093/cid/ciaa215.Full Text Link to Item
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Alexander, Barbara D., Frédéric Lamoth, Claus Peter Heussel, Cornelia Schaefer Prokop, Sujal R. Desai, C Orla Morrissey, and John W. Baddley. “Guidance on Imaging for Invasive Pulmonary Aspergillosis and Mucormycosis: From the Imaging Working Group for the Revision and Update of the Consensus Definitions of Fungal Disease from the EORTC/MSGERC.” Clin Infect Dis 72, no. Suppl 2 (March 12, 2021): S79–88. https://doi.org/10.1093/cid/ciaa1855.Full Text Link to Item
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Baker, Arthur W., and Barbara D. Alexander. “Reply to Marinelli and Rotstein.” Clin Infect Dis 72, no. 2 (January 27, 2021): 366–67. https://doi.org/10.1093/cid/ciaa605.Full Text Link to Item
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Salmanton-García, Jon, Philipp Koehler, Anupma Kindo, Iker Falces-Romero, Julio García-Rodríguez, Zdeněk Ráčil, Sharon C-A Chen, et al. “Needles in a haystack: Extremely rare invasive fungal infections reported in FungiScopeⓇ-Global Registry for Emerging Fungal Infections.” J Infect 81, no. 5 (November 2020): 802–15. https://doi.org/10.1016/j.jinf.2020.08.015.Full Text Link to Item
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Sears, Cynthia L., William G. Powderly, Paul G. Auwaerter, Barbara D. Alexander, and Thomas M. File. “Pathways to Leadership: Reflections of Recent Infectious Diseases Society of America (IDSA) Leaders During Conception and Launch of the Inclusion, Diversity, Access, and Equity Movement Within the IDSA.” J Infect Dis 222, no. Suppl 6 (September 14, 2020): S554–59. https://doi.org/10.1093/infdis/jiaa297.Full Text Link to Item
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Donnelly, J Peter, Sharon C. Chen, Carol A. Kauffman, William J. Steinbach, John W. Baddley, Paul E. Verweij, Cornelius J. Clancy, et al. “Revision and Update of the Consensus Definitions of Invasive Fungal Disease From the European Organization for Research and Treatment of Cancer and the Mycoses Study Group Education and Research Consortium.” Clin Infect Dis 71, no. 6 (September 12, 2020): 1367–76. https://doi.org/10.1093/cid/ciz1008.Full Text Open Access Copy Link to Item
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Miller, Rachel A., and Barbara D. Alexander. “Editorial: Infections of the immunocompromised host: a musing on the changing times.” Curr Opin Infect Dis 33, no. 4 (August 2020): 279–80. https://doi.org/10.1097/QCO.0000000000000660.Full Text Link to Item
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Permpalung, Nitipong, Tany Thaniyavarn, Jennifer L. Saullo, Sana Arif, Rachel A. Miller, John M. Reynolds, and Barbara D. Alexander. “Oral and Inhaled Ribavirin Treatment for Respiratory Syncytial Virus Infection in Lung Transplant Recipients.” Transplantation 104, no. 6 (June 2020): 1280–86. https://doi.org/10.1097/TP.0000000000002985.Full Text Link to Item
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Baker, Arthur W., and Barbara D. Alexander. “Reply to Authors (Drs. Marinelli and Rotstein).” Clin Infect Dis, May 23, 2020. https://doi.org/10.1093/cid/ciaa605.Full Text Link to Item
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Hemmersbach-Miller, Marion, Barbara D. Alexander, Carl F. Pieper, and Kenneth E. Schmader. “Age matters: older age as a risk factor for CMV reactivation in the CMV serostatus-positive kidney transplant recipient.” Eur J Clin Microbiol Infect Dis 39, no. 3 (March 2020): 455–63. https://doi.org/10.1007/s10096-019-03744-3.Full Text Link to Item
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Saullo, Jennifer L., Yanhong Li, Julia A. Messina, Jillian Thompson, Tara Dalton, Vinay K. Giri, Shelby D. Reed, et al. “Cytomegalovirus in Allogeneic Hematopoietic Transplantation: Impact on Costs and Clinical Outcomes Using a Preemptive Strategy.” Biol Blood Marrow Transplant 26, no. 3 (March 2020): 568–80. https://doi.org/10.1016/j.bbmt.2019.11.005.Full Text Link to Item
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Stemler, Jannik, Jon Salmanton-García, Danila Seidel, Barbara D. Alexander, Hartmut Bertz, Martin Hoenigl, Raoul Herbrecht, et al. “Risk factors and mortality in invasive Rasamsonia spp. infection: Analysis of cases in the FungiScope® registry and from the literature.” Mycoses 63, no. 3 (March 2020): 265–74. https://doi.org/10.1111/myc.13039.Full Text Link to Item
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Baker, Arthur W., Eileen K. Maziarz, Christopher J. Arnold, Melissa D. Johnson, Adrienne D. Workman, John M. Reynolds, John R. Perfect, and Barbara D. Alexander. “Invasive Fungal Infection After Lung Transplantation: Epidemiology in the Setting of Antifungal Prophylaxis.” Clin Infect Dis 70, no. 1 (January 1, 2020): 30–39. https://doi.org/10.1093/cid/ciz156.Full Text Link to Item
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McGowan, Elisabeth C., Abbot R. Laptook, Jean Lowe, Myriam Peralta-Carcelen, Dhuly Chowdhury, Rosemary D. Higgins, Susan R. Hintz, Betty R. Vohr, and Betty R. Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. “Developmental Outcomes of Extremely Preterm Infants with a Need for Child Protective Services Supervision.” J Pediatr 215 (December 2019): 41-49.e4. https://doi.org/10.1016/j.jpeds.2019.07.063.Full Text Link to Item
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Sears, Cynthia L., Thomas M. File, Barbara D. Alexander, Daniel P. McQuillen, Ann T. MacIntyre, Upton D. Allen, Jonathan A. Colasanti, et al. “Charting the Path Forward: Development, Goals and Initiatives of the 2019 Infectious Diseases Society of America Strategic Plan.” Clin Infect Dis 69, no. 12 (November 27, 2019): e1–7. https://doi.org/10.1093/cid/ciz1040.Full Text Link to Item
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Foglia, Elizabeth E., Benjamin Carper, Marie Gantz, Sara B. DeMauro, Satyan Lakshminrusimha, Michele Walsh, Barbara Schmidt, and Barbara Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. “Association between Policy Changes for Oxygen Saturation Alarm Settings and Neonatal Morbidity and Mortality in Infants Born Very Preterm.” J Pediatr 209 (June 2019): 17-22.e2. https://doi.org/10.1016/j.jpeds.2019.01.048.Full Text Link to Item
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Ryan, Rita M., Roberta L. Keller, Brenda B. Poindexter, Carl T. D’Angio, Pamela A. Shaw, Scarlett L. Bellamy, Paul E. Moore, Christopher McPherson, James M. Greenberg, and James M. PROP Investigators. “Respiratory Medications in Infants <29 Weeks during the First Year Postdischarge: The Prematurity and Respiratory Outcomes Program (PROP) Consortium.” J Pediatr 208 (May 2019): 148-155.e3. https://doi.org/10.1016/j.jpeds.2018.12.009.Full Text Link to Item
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Hemmersbach-Miller, Marion, Barbara D. Alexander, Debra L. Sudan, Carl Pieper, and Kenneth E. Schmader. “Infections after kidney transplantation. Does age matter?” Clin Transplant 33, no. 4 (April 2019): e13516. https://doi.org/10.1111/ctr.13516.Full Text Link to Item
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Chung, Shimin Jasmine, Rachel Ann Miller, Nitipong Permpalung, Arthur Wakefield Baker, Louis Frederic Diehl, David Alan Rizzieri, and Barbara Dudley Alexander. “Fluoroquinolone prophylaxis reduces febrile neutropenia, bloodstream infections from mucosal translocations, and intensive care admissions in high risk hematological patients, a single center experience.” Leuk Lymphoma 60, no. 2 (February 2019): 488–92. https://doi.org/10.1080/10428194.2018.1488252.Full Text Link to Item
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Mullane, Kathleen M., Drew J. Winston, Ajay Nooka, Michele I. Morris, Patrick Stiff, Michael J. Dugan, Henry Holland, et al. “A Randomized, Placebo-controlled Trial of Fidaxomicin for Prophylaxis of Clostridium difficile-associated Diarrhea in Adults Undergoing Hematopoietic Stem Cell Transplantation.” Clin Infect Dis 68, no. 2 (January 7, 2019): 196–203. https://doi.org/10.1093/cid/ciy484.Full Text Open Access Copy Link to Item
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Hemmersbach-Miller, Marion, Barbara D. Alexander, Debra L. Sudan, Carl Pieper, and Kenneth E. Schmader. “Single-center analysis of infectious complications in older adults during the first year after kidney transplantation.” Eur J Clin Microbiol Infect Dis 38, no. 1 (January 2019): 141–48. https://doi.org/10.1007/s10096-018-3405-5.Full Text Link to Item
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Shankaran, Seetha, Edward F. Bell, Abbot R. Laptook, Shampa Saha, Nancy S. Newman, S Nadya J. Kazzi, John Barks, et al. “Weaning of Moderately Preterm Infants from the Incubator to the Crib: A Randomized Clinical Trial.” J Pediatr 204 (January 2019): 96-102.e4. https://doi.org/10.1016/j.jpeds.2018.08.079.Full Text Link to Item
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Messina, Julia A., Cameron R. Wolfe, Marion Hemmersbach-Miller, Carmelo Milano, Jamie L. Todd, John Reynolds, Barbara D. Alexander, Wiley A. Schell, Christina A. Cuomo, and John R. Perfect. “Genomic characterization of recurrent mold infections in thoracic transplant recipients.” Transpl Infect Dis 20, no. 5 (October 2018): e12935. https://doi.org/10.1111/tid.12935.Full Text Link to Item
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Messina, Julia A., Rohita Sinha, Kimberly Starr, Mehreen Arshad, Barbara D. Alexander, Nelson J. Chao, and Anthony D. Sung. “Clinical and Genomic Characterization of Recurrent Enterococcal Bloodstream Infection in Patients With Acute Leukemia.” Open Forum Infect Dis 5, no. 6 (June 2018): ofy107. https://doi.org/10.1093/ofid/ofy107.Full Text Open Access Copy Link to Item
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Adams-Chapman, Ira, Roy J. Heyne, Sara B. DeMauro, Andrea F. Duncan, Susan R. Hintz, Athina Pappas, Betty R. Vohr, et al. “Neurodevelopmental Impairment Among Extremely Preterm Infants in the Neonatal Research Network.” Pediatrics 141, no. 5 (May 2018). https://doi.org/10.1542/peds.2017-3091.Full Text Link to Item
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Bajaj, Monika, Girija Natarajan, Seetha Shankaran, Myra Wyckoff, Abbot R. Laptook, Edward F. Bell, Barbara J. Stoll, et al. “Delivery Room Resuscitation and Short-Term Outcomes in Moderately Preterm Infants.” J Pediatr 195 (April 2018): 33-38.e2. https://doi.org/10.1016/j.jpeds.2017.11.039.Full Text Link to Item
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Natarajan, Girija, Seetha Shankaran, Shampa Saha, Abbot Laptook, Abhik Das, Rosemary Higgins, Barbara J. Stoll, et al. “Antecedents and Outcomes of Abnormal Cranial Imaging in Moderately Preterm Infants.” J Pediatr 195 (April 2018): 66-72.e3. https://doi.org/10.1016/j.jpeds.2017.11.036.Full Text Link to Item
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Sarkar, Subrata, Seetha Shankaran, John Barks, Barbara T. Do, Abbot R. Laptook, Abhik Das, Namasivayam Ambalavanan, et al. “Outcome of Preterm Infants with Transient Cystic Periventricular Leukomalacia on Serial Cranial Imaging Up to Term Equivalent Age.” J Pediatr 195 (April 2018): 59-65.e3. https://doi.org/10.1016/j.jpeds.2017.12.010.Full Text Link to Item
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Laptook, Abbot R., Edward F. Bell, Seetha Shankaran, Nansi S. Boghossian, Myra H. Wyckoff, Sarah Kandefer, Michele Walsh, Shampa Saha, Rosemary Higgins, and Rosemary Generic and Moderate Preterm Subcommittees of the NICHD Neonatal Research Network. “Admission Temperature and Associated Mortality and Morbidity among Moderately and Extremely Preterm Infants.” J Pediatr 192 (January 2018): 53-59.e2. https://doi.org/10.1016/j.jpeds.2017.09.021.Full Text Link to Item
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Pappas, Athina, Ira Adams-Chapman, Seetha Shankaran, Scott A. McDonald, Barbara J. Stoll, Abbot R. Laptook, Waldemar A. Carlo, et al. “Neurodevelopmental and Behavioral Outcomes in Extremely Premature Neonates With Ventriculomegaly in the Absence of Periventricular-Intraventricular Hemorrhage.” Jama Pediatr 172, no. 1 (January 1, 2018): 32–42. https://doi.org/10.1001/jamapediatrics.2017.3545.Full Text Link to Item
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Schell, Wiley A., A. M. Jones, Katyna Borroto-Esoda, and Barbara D. Alexander. “Antifungal Activity of SCY-078 and Standard Antifungal Agents against 178 Clinical Isolates of Resistant and Susceptible Candida Species.” Antimicrob Agents Chemother 61, no. 11 (November 2017). https://doi.org/10.1128/AAC.01102-17.Full Text Link to Item
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Lamoth, Frederic, Shimin J. Chung, Lauro Damonti, and Barbara D. Alexander. “Changing Epidemiology of Invasive Mold Infections in Patients Receiving Azole Prophylaxis.” Clin Infect Dis 64, no. 11 (June 1, 2017): 1619–21. https://doi.org/10.1093/cid/cix130.Full Text Link to Item
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Lockhart, Shawn R., Mahmoud A. Ghannoum, and Barbara D. Alexander. “Establishment and Use of Epidemiological Cutoff Values for Molds and Yeasts by Use of the Clinical and Laboratory Standards Institute M57 Standard.” J Clin Microbiol 55, no. 5 (May 2017): 1262–68. https://doi.org/10.1128/JCM.02416-16.Full Text Link to Item
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Baker, Arthur W., Sarah S. Lewis, Barbara D. Alexander, Luke F. Chen, Richard J. Wallace, Barbara A. Brown-Elliott, Pamela J. Isaacs, et al. “Two-Phase Hospital-Associated Outbreak of Mycobacterium abscessus: Investigation and Mitigation.” Clin Infect Dis 64, no. 7 (April 1, 2017): 902–11. https://doi.org/10.1093/cid/ciw877.Full Text Link to Item
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Schell, W. A., A. M. Jones, E. P. Garvey, W. J. Hoekstra, R. J. Schotzinger, and B. D. Alexander. “Fungal CYP51 Inhibitors VT-1161 and VT-1129 Exhibit Strong In Vitro Activity against Candida glabrata and C. krusei Isolates Clinically Resistant to Azole and Echinocandin Antifungal Compounds.” Antimicrob Agents Chemother 61, no. 3 (March 2017). https://doi.org/10.1128/AAC.01817-16.Full Text Link to Item
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Hemmersbach-Miller, M., J. Duronville, S. Sethi, S. E. Miller, D. N. Howell, N. Henshaw, B. D. Alexander, and J. K. Roberts. “Hemorrhagic Herpes Simplex Virus Type 1 Nephritis: An Unusual Cause of Acute Allograft Dysfunction.” Am J Transplant 17, no. 1 (January 2017): 287–91. https://doi.org/10.1111/ajt.14022.Full Text Open Access Copy Link to Item
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Revankar, Sanjay G., John W. Baddley, Sharon C-A Chen, Carol A. Kauffman, Monica Slavin, Jose A. Vazquez, Carlos Seas, et al. “A Mycoses Study Group International Prospective Study of Phaeohyphomycosis: An Analysis of 99 Proven/Probable Cases.” Open Forum Infect Dis 4, no. 4 (2017): ofx200. https://doi.org/10.1093/ofid/ofx200.Full Text Open Access Copy Link to Item
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Andes, David R., Nasia Safdar, John W. Baddley, Barbara Alexander, Lisa Brumble, Allison Freifeld, Susan Hadley, et al. “The epidemiology and outcomes of invasive Candida infections among organ transplant recipients in the United States: results of the Transplant-Associated Infection Surveillance Network (TRANSNET).” Transpl Infect Dis 18, no. 6 (December 2016): 921–31. https://doi.org/10.1111/tid.12613.Full Text Link to Item
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Abril, Maria K., Adam S. Barnett, Kara Wegermann, Eric Fountain, Andrew Strand, Benjamin M. Heyman, Britton A. Blough, et al. “Diagnosis of Capnocytophaga canimorsus Sepsis by Whole-Genome Next-Generation Sequencing.” Open Forum Infect Dis 3, no. 3 (September 2016): ofw144. https://doi.org/10.1093/ofid/ofw144.Full Text Open Access Copy Link to Item
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“Sun HY, et al (Clin Infect Dis 2015; 60:36-44).” Clin Infect Dis 62, no. 12 (June 15, 2016): 1621. https://doi.org/10.1093/cid/ciw246.Full Text Link to Item
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Lamoth, Frédéric, Lauro Damonti, and Barbara D. Alexander. “Role of Antifungal Susceptibility Testing in Non-Aspergillus Invasive Mold Infections.” J Clin Microbiol 54, no. 6 (June 2016): 1638–40. https://doi.org/10.1128/JCM.00318-16.Full Text Link to Item
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Healey, Kelley R., Yanan Zhao, Winder B. Perez, Shawn R. Lockhart, Jack D. Sobel, Dimitrios Farmakiotis, Dimitrios P. Kontoyiannis, et al. “Prevalent mutator genotype identified in fungal pathogen Candida glabrata promotes multi-drug resistance.” Nat Commun 7 (March 29, 2016): 11128. https://doi.org/10.1038/ncomms11128.Full Text Open Access Copy Link to Item
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Husain, Shahid, Amparo Sole, Barbara D. Alexander, Saima Aslam, Robin Avery, Christian Benden, Eliane M. Billaud, et al. “The 2015 International Society for Heart and Lung Transplantation Guidelines for the management of fungal infections in mechanical circulatory support and cardiothoracic organ transplant recipients: Executive summary.” J Heart Lung Transplant 35, no. 3 (March 2016): 261–82. https://doi.org/10.1016/j.healun.2016.01.007.Full Text Link to Item
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Swamydas, Muthulekha, Ji-Liang Gao, Timothy J. Break, Melissa D. Johnson, Martin Jaeger, Carlos A. Rodriguez, Jean K. Lim, et al. “CXCR1-mediated neutrophil degranulation and fungal killing promote Candida clearance and host survival.” Sci Transl Med 8, no. 322 (January 20, 2016): 322ra10. https://doi.org/10.1126/scitranslmed.aac7718.Full Text Link to Item
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Lamoth, Frédéric, and Barbara D. Alexander. “Comparing Etest and Broth Microdilution for Antifungal Susceptibility Testing of the Most-Relevant Pathogenic Molds.” J Clin Microbiol 53, no. 10 (October 2015): 3176–81. https://doi.org/10.1128/JCM.00925-15.Full Text Link to Item
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Lamoth, Frédéric, and Barbara D. Alexander. “Antifungal activities of SCY-078 (MK-3118) and standard antifungal agents against clinical non-Aspergillus mold isolates.” Antimicrob Agents Chemother 59, no. 7 (July 2015): 4308–11. https://doi.org/10.1128/AAC.00234-15.Full Text Link to Item
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McCarty, Todd P., John W. Baddley, Thomas J. Walsh, Barbara D. Alexander, Dimitrios P. Kontoyiannis, Trish M. Perl, Randall Walker, et al. “Phaeohyphomycosis in transplant recipients: Results from the Transplant Associated Infection Surveillance Network (TRANSNET).” Med Mycol 53, no. 5 (June 2015): 440–46. https://doi.org/10.1093/mmy/myv018.Full Text Link to Item
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Lamoth, Frédéric, Barbara D. Alexander, Praveen R. Juvvadi, and William J. Steinbach. “Antifungal activity of compounds targeting the Hsp90-calcineurin pathway against various mould species.” J Antimicrob Chemother 70, no. 5 (May 2015): 1408–11. https://doi.org/10.1093/jac/dku549.Full Text Link to Item
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Patel, Ravi M., Sarah Kandefer, Michele C. Walsh, Edward F. Bell, Waldemar A. Carlo, Abbot R. Laptook, Pablo J. Sánchez, et al. “Causes and timing of death in extremely premature infants from 2000 through 2011.” N Engl J Med 372, no. 4 (January 22, 2015): 331–40. https://doi.org/10.1056/NEJMoa1403489.Full Text Link to Item
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Brasier, Allan R., Yingxin Zhao, Heidi M. Spratt, John E. Wiktorowicz, Hyunsu Ju, L Joseph Wheat, Lindsey Baden, et al. “Improved Detection of Invasive Pulmonary Aspergillosis Arising during Leukemia Treatment Using a Panel of Host Response Proteins and Fungal Antigens.” Plos One 10, no. 11 (2015): e0143165. https://doi.org/10.1371/journal.pone.0143165.Full Text Open Access Copy Link to Item
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Sun, Hsin-Yun, Barbara D. Alexander, Shirish Huprikar, Graeme N. Forrest, Didier Bruno, G Marshall Lyon, Dannah Wray, et al. “Predictors of immune reconstitution syndrome in organ transplant recipients with cryptococcosis: implications for the management of immunosuppression.” Clin Infect Dis 60, no. 1 (January 1, 2015): 36–44. https://doi.org/10.1093/cid/ciu711.Full Text Link to Item
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Wheat, L Joseph, M Hong Nguyen, Barbara D. Alexander, David Denning, Angela M. Caliendo, G Marshall Lyon, Lindsey R. Baden, et al. “Reply to "Insufficient demonstration of long-term stability of Aspergillus galactomannan".” J Clin Microbiol 52, no. 11 (November 2014): 4119. https://doi.org/10.1128/JCM.02433-14.Full Text Link to Item
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Horan, J. L., J. E. Stout, and B. D. Alexander. “Hepatitis B core antibody-positive donors in cardiac transplantation: a single-center experience.” Transpl Infect Dis 16, no. 5 (October 2014): 859–63. https://doi.org/10.1111/tid.12280.Full Text Link to Item
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Barker, Adam P., Jennifer L. Horan, E Susan Slechta, Barbara D. Alexander, and Kimberly E. Hanson. “Complexities associated with the molecular and proteomic identification of Paecilomyces species in the clinical mycology laboratory.” Med Mycol 52, no. 5 (July 2014): 537–45. https://doi.org/10.1093/mmy/myu001.Full Text Link to Item
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Doligalski, C. T., K. Benedict, A. A. Cleveland, B. Park, G. Derado, P. G. Pappas, J. W. Baddley, D. W. Zaas, M. T. Harris, and B. D. Alexander. “Epidemiology of invasive mold infections in lung transplant recipients.” Am J Transplant 14, no. 6 (June 2014): 1328–33. https://doi.org/10.1111/ajt.12691.Full Text Link to Item
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Lamoth, Frédéric, and Barbara D. Alexander. “Nonmolecular methods for the diagnosis of respiratory fungal infections.” Clin Lab Med 34, no. 2 (June 2014): 315–36. https://doi.org/10.1016/j.cll.2014.02.006.Full Text Link to Item
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Wheat, L Joseph, M Hong Nguyen, Barbara D. Alexander, David Denning, Angela M. Caliendo, G Marshall Lyon, Lindsey R. Baden, et al. “Long-term stability at -20 °C of Aspergillus galactomannan in serum and bronchoalveolar lavage specimens.” J Clin Microbiol 52, no. 6 (June 2014): 2108–11. https://doi.org/10.1128/JCM.03500-13.Full Text Link to Item
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Rosentul, Diana C., Theo S. Plantinga, Marius Farcas, Marije Oosting, Omar J. M. Hamza, William K. Scott, Barbara D. Alexander, et al. “Role of autophagy genetic variants for the risk of Candida infections.” Med Mycol 52, no. 4 (May 2014): 333–41. https://doi.org/10.1093/mmy/myt035.Full Text Link to Item
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Kauffman, C. A., A. G. Freifeld, D. R. Andes, J. W. Baddley, L. Herwaldt, R. C. Walker, B. D. Alexander, et al. “Endemic fungal infections in solid organ and hematopoietic cell transplant recipients enrolled in the Transplant-Associated Infection Surveillance Network (TRANSNET).” Transpl Infect Dis 16, no. 2 (April 2014): 213–24. https://doi.org/10.1111/tid.12186.Full Text Link to Item
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Alexander, B. D., M. D. Johnson, C. D. Pfeiffer, C. Jiménez-Ortigosa, J. Catania, and R. Booker. “Erratum: Increasing echinocandin resistance in Candida glabrata: Clinical failure correlates with presence of FKS mutations and elevated minimum inhibitory concentrations (Clinical Infectious Diseases (2013) 56 (1724-32)).” Clinical Infectious Diseases 58, no. 5 (March 1, 2014): 754. https://doi.org/10.1093/cid/cit956.Full Text
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Lionakis, Michail S., Muthulekha Swamydas, Brett G. Fischer, Theo S. Plantinga, Melissa D. Johnson, Martin Jaeger, Nathaniel M. Green, et al. “CX3CR1-dependent renal macrophage survival promotes Candida control and host survival.” J Clin Invest 123, no. 12 (December 2013): 5035–51. https://doi.org/10.1172/JCI71307.Full Text Link to Item
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Lyon, G Marshall, Deborah Abdul-Ali, Juergen Loeffler, P Lewis White, Brian Wickes, Monica L. Herrera, Barbara D. Alexander, et al. “Development and evaluation of a calibrator material for nucleic acid-based assays for diagnosing aspergillosis.” J Clin Microbiol 51, no. 7 (July 2013): 2403–5. https://doi.org/10.1128/JCM.00744-13.Full Text Link to Item
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Alexander, Barbara D., Melissa D. Johnson, Christopher D. Pfeiffer, Cristina Jiménez-Ortigosa, Jelena Catania, Rachel Booker, Mariana Castanheira, Shawn A. Messer, David S. Perlin, and Michael A. Pfaller. “Increasing echinocandin resistance in Candida glabrata: clinical failure correlates with presence of FKS mutations and elevated minimum inhibitory concentrations.” Clin Infect Dis 56, no. 12 (June 2013): 1724–32. https://doi.org/10.1093/cid/cit136.Full Text Link to Item
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Westervelt, Justin D., Barbara D. Alexander, Sylvia F. Costa, Sara E. Miller, David N. Howell, and Stephen R. Smith. “Detection of BK polyomavirus after kidney transplantation: a comparison of urine electron microscopy with plasma polymerase chain reaction.” Clin Transplant 27, no. 1 (2013): E42–48. https://doi.org/10.1111/ctr.12048.Full Text Link to Item
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Dodds Ashley, Elizabeth, Richard Drew, Melissa Johnson, Robert Danna, Dominika Dabrowski, Valery Walker, Manishi Prasad, Barbara Alexander, George Papadopoulos, and John Perfect. “Cost of invasive fungal infections in the era of new diagnostics and expanded treatment options.” Pharmacotherapy 32, no. 10 (October 2012): 890–901. https://doi.org/10.1002/j.1875-9114.2012.01124.Full Text Link to Item
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Schell, W. A., J. L. Benton, P. B. Smith, M. Poore, J. L. Rouse, D. J. Boles, M. D. Johnson, et al. “Evaluation of a digital microfluidic real-time PCR platform to detect DNA of Candida albicans in blood.” Eur J Clin Microbiol Infect Dis 31, no. 9 (September 2012): 2237–45. https://doi.org/10.1007/s10096-012-1561-6.Full Text Open Access Copy Link to Item
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Plantinga, Theo S., Melissa D. Johnson, William K. Scott, Esther van de Vosse, Digna R. Velez Edwards, P Brian Smith, Barbara D. Alexander, et al. “Toll-like receptor 1 polymorphisms increase susceptibility to candidemia.” J Infect Dis 205, no. 6 (March 15, 2012): 934–43. https://doi.org/10.1093/infdis/jir867.Full Text Link to Item
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Rosentul, D. C., T. S. Plantinga, W. K. Scott, B. D. Alexander, N. M. D. van de Geer, J. R. Perfect, B. J. Kullberg, M. D. Johnson, and M. G. Netea. “The impact of caspase-12 on susceptibility to candidemia.” Eur J Clin Microbiol Infect Dis 31, no. 3 (March 2012): 277–80. https://doi.org/10.1007/s10096-011-1307-x.Full Text Open Access Copy Link to Item
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Johnson, Melissa D., Theo S. Plantinga, Esther van de Vosse, Digna R. Velez Edwards, P Brian Smith, Barbara D. Alexander, John C. Yang, et al. “Cytokine gene polymorphisms and the outcome of invasive candidiasis: a prospective cohort study.” Clin Infect Dis 54, no. 4 (February 15, 2012): 502–10. https://doi.org/10.1093/cid/cir827.Full Text Open Access Copy Link to Item
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Hanson, Kimberly E., Christopher D. Pfeiffer, Erika D. Lease, Alfred H. Balch, Aimee K. Zaas, John R. Perfect, and Barbara D. Alexander. “β-D-glucan surveillance with preemptive anidulafungin for invasive candidiasis in intensive care unit patients: a randomized pilot study.” Plos One 7, no. 8 (2012): e42282. https://doi.org/10.1371/journal.pone.0042282.Full Text Open Access Copy Link to Item
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Lease, Erika D., and Barbara D. Alexander. “Fungal diagnostics in pneumonia.” Semin Respir Crit Care Med 32, no. 6 (December 2011): 663–72. https://doi.org/10.1055/s-0031-1295714.Full Text Link to Item
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Park, Benjamin J., Peter G. Pappas, Kathleen A. Wannemuehler, Barbara D. Alexander, Elias J. Anaissie, David R. Andes, John W. Baddley, et al. “Invasive non-Aspergillus mold infections in transplant recipients, United States, 2001-2006.” Emerg Infect Dis 17, no. 10 (October 2011): 1855–64. https://doi.org/10.3201/eid1710.110087.Full Text Open Access Copy Link to Item
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Rosentul, Diana C., Theo S. Plantinga, Marije Oosting, William K. Scott, Digna R. Velez Edwards, P Brian Smith, Barbara D. Alexander, et al. “Genetic variation in the dectin-1/CARD9 recognition pathway and susceptibility to candidemia.” J Infect Dis 204, no. 7 (October 1, 2011): 1138–45. https://doi.org/10.1093/infdis/jir458.Full Text Link to Item
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Pfeiffer, Christopher D., Gregory P. Samsa, Wiley A. Schell, L Barth Reller, John R. Perfect, and Barbara D. Alexander. “Quantitation of Candida CFU in initial positive blood cultures.” J Clin Microbiol 49, no. 8 (August 2011): 2879–83. https://doi.org/10.1128/JCM.00609-11.Full Text Link to Item
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Pfaller, Michael A., David Andes, Maiken C. Arendrup, Daniel J. Diekema, Ana Espinel-Ingroff, Barbara D. Alexander, Steven D. Brown, et al. “Clinical breakpoints for voriconazole and Candida spp. revisited: review of microbiologic, molecular, pharmacodynamic, and clinical data as they pertain to the development of species-specific interpretive criteria.” Diagn Microbiol Infect Dis 70, no. 3 (July 2011): 330–43. https://doi.org/10.1016/j.diagmicrobio.2011.03.002.Full Text Link to Item
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Hauser, Philippe M., Jacques Bille, Cornelia Lass-Flörl, Christian Geltner, Marta Feldmesser, Michael Levi, Hitesh Patel, et al. “Multicenter, prospective clinical evaluation of respiratory samples from subjects at risk for Pneumocystis jirovecii infection by use of a commercial real-time PCR assay.” J Clin Microbiol 49, no. 5 (May 2011): 1872–78. https://doi.org/10.1128/JCM.02390-10.Full Text Link to Item
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Person, Anna K., Dimitrios P. Kontoyiannis, and Barbara D. Alexander. “Fungal infections in transplant and oncology patients.” Hematol Oncol Clin North Am 25, no. 1 (February 2011): 193–213. https://doi.org/10.1016/j.hoc.2010.11.013.Full Text Link to Item
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Alexander, Barbara D., Thomas P. Winkler, Shuai Shi, Elizabeth S Dodds Ashley, and Anthony J. Hickey. “Nebulizer delivery of micafungin aerosols.” Pharmacotherapy 31, no. 1 (January 2011): 52–57. https://doi.org/10.1592/phco.31.1.52.Full Text Link to Item
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Alexander, Barbara D., Thomas P. Winkler, Shuai Shi, Elizabeth S. Dodds Ashley, and Anthony J. Hickey. “In vitro characterization of nebulizer delivery of liposomal amphotericin B aerosols.” Pharm Dev Technol 16, no. 6 (2011): 577–82. https://doi.org/10.3109/10837450.2011.591803.Full Text Link to Item
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Park, B. J., P. G. Pappas, K. A. Wannemuehler, B. D. Alexander, E. J. Anaissie, D. R. Andes, J. W. Baddley, et al. “Invasive non-Aspergillus mold infections in transplant recipients, United States, 2001-2006.” Emerging Infectious Diseases 17, no. 10 (January 1, 2011): 1855–64. https://doi.org/10.3201/eid1710.110087.Full Text
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Alexander, Barbara D., P Brian Smith, R Duane Davis, John R. Perfect, and L Barth Reller. “The (1,3){beta}-D-glucan test as an aid to early diagnosis of invasive fungal infections following lung transplantation.” J Clin Microbiol 48, no. 11 (November 2010): 4083–88. https://doi.org/10.1128/JCM.01183-10.Full Text Link to Item
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Sun, Hsin-Yun, Barbara D. Alexander, Olivier Lortholary, Francoise Dromer, Graeme N. Forrest, G Marshall Lyon, Jyoti Somani, et al. “Unrecognized pretransplant and donor‐derived cryptococcal disease in organ transplant recipients.” Clin Infect Dis 51, no. 9 (November 1, 2010): 1062–69. https://doi.org/10.1086/656584.Full Text Open Access Copy Link to Item
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Alexander, B. D., W. A. Schell, A. M. Siston, C. Y. Rao, W. A. Bower, S. A. Balajee, D. N. Howell, et al. “Fatal Apophysomyces elegans infection transmitted by deceased donor renal allografts.” Am J Transplant 10, no. 9 (September 2010): 2161–67. https://doi.org/10.1111/j.1600-6143.2010.03216.x.Full Text Link to Item
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Sun, Hsin-Yun, Barbara D. Alexander, Olivier Lortholary, Francoise Dromer, Graeme N. Forrest, G Marshall Lyon, Jyoti Somani, et al. “Cutaneous cryptococcosis in solid organ transplant recipients.” Med Mycol 48, no. 6 (September 2010): 785–91. https://doi.org/10.3109/13693780903496617.Full Text Link to Item
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Harrison, Elizabeth, Thomas Stalhberger, Ruth Whelan, Michele Sugrue, John R. Wingard, Barbara D. Alexander, Sarah A. Follett, Paul Bowyer, David W. Denning, and David W. Aspergillus Technology Consortium (AsTeC). “Aspergillus DNA contamination in blood collection tubes.” Diagn Microbiol Infect Dis 67, no. 4 (August 2010): 392–94. https://doi.org/10.1016/j.diagmicrobio.2010.02.028.Full Text Link to Item
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Pfeiffer, Christopher D., Guillermo Garcia-Effron, Aimee K. Zaas, John R. Perfect, David S. Perlin, and Barbara D. Alexander. “Breakthrough invasive candidiasis in patients on micafungin.” J Clin Microbiol 48, no. 7 (July 2010): 2373–80. https://doi.org/10.1128/JCM.02390-09.Full Text Link to Item
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Baddley, John W., David R. Andes, Kieren A. Marr, Dimitrios P. Kontoyiannis, Barbara D. Alexander, Carol A. Kauffman, Robert A. Oster, et al. “Factors associated with mortality in transplant patients with invasive aspergillosis.” Clin Infect Dis 50, no. 12 (June 15, 2010): 1559–67. https://doi.org/10.1086/652768.Full Text Open Access Copy Link to Item
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Person, Anna K., Dimitrios P. Kontoyiannis, and Barbara D. Alexander. “Fungal infections in transplant and oncology patients.” Infect Dis Clin North Am 24, no. 2 (June 2010): 439–59. https://doi.org/10.1016/j.idc.2010.01.002.Full Text Link to Item
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Wulff-Burchfield, Elizabeth, Wiley A. Schell, Allen E. Eckhardt, Michael G. Pollack, Zhishan Hua, Jeremy L. Rouse, Vamsee K. Pamula, et al. “Microfluidic platform versus conventional real-time polymerase chain reaction for the detection of Mycoplasma pneumoniae in respiratory specimens.” Diagn Microbiol Infect Dis 67, no. 1 (May 2010): 22–29. https://doi.org/10.1016/j.diagmicrobio.2009.12.020.Full Text Open Access Copy Link to Item
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Kontoyiannis, Dimitrios P., Kieren A. Marr, Benjamin J. Park, Barbara D. Alexander, Elias J. Anaissie, Thomas J. Walsh, James Ito, et al. “Prospective surveillance for invasive fungal infections in hematopoietic stem cell transplant recipients, 2001-2006: overview of the Transplant-Associated Infection Surveillance Network (TRANSNET) Database.” Clin Infect Dis 50, no. 8 (April 15, 2010): 1091–1100. https://doi.org/10.1086/651263.Full Text Open Access Copy Link to Item
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Pappas, Peter G., Barbara D. Alexander, David R. Andes, Susan Hadley, Carol A. Kauffman, Alison Freifeld, Elias J. Anaissie, et al. “Invasive fungal infections among organ transplant recipients: results of the Transplant-Associated Infection Surveillance Network (TRANSNET).” Clin Infect Dis 50, no. 8 (April 15, 2010): 1101–11. https://doi.org/10.1086/651262.Full Text Open Access Copy Link to Item
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Nowell, L., C. Moran, P. B. Smith, P. Seed, B. D. Alexander, C. M. Cotten, J. S. Wiener, and D. K. Benjamin. “Prevalence of renal anomalies after urinary tract infections in hospitalized infants less than 2 months of age.” J Perinatol 30, no. 4 (April 2010): 281–85. https://doi.org/10.1038/jp.2009.147.Full Text Open Access Copy Link to Item
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Osawa, Ryosuke, Barbara D. Alexander, Olivier Lortholary, Françoise Dromer, Graeme N. Forrest, G Marshall Lyon, Jyoti Somani, et al. “Identifying predictors of central nervous system disease in solid organ transplant recipients with cryptococcosis.” Transplantation 89, no. 1 (January 15, 2010): 69–74. https://doi.org/10.1097/TP.0b013e3181bcda41.Full Text Link to Item
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Osawa, Ryosuke, Barbara D. Alexander, Graeme N. Forrest, G Marshall Lyon, Jyoti Somani, Ramon del Busto, Timothy L. Pruett, et al. “Geographic differences in disease expression of cryptococcosis in solid organ transplant recipients in the United States.” Ann Transplant 15, no. 4 (2010): 77–83.Link to Item
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Sun, Hsin-Yun, Barbara D. Alexander, Olivier Lortholary, Francoise Dromer, Graeme N. Forrest, G Marshall Lyon, Jyoti Somani, et al. “Lipid formulations of amphotericin B significantly improve outcome in solid organ transplant recipients with central nervous system cryptococcosis.” Clin Infect Dis 49, no. 11 (December 1, 2009): 1721–28. https://doi.org/10.1086/647948.Full Text Link to Item
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Radack, Kyle P., and Barbara D. Alexander. “Prophylaxis of invasive mycoses in solid organ transplantation.” Curr Infect Dis Rep 11, no. 6 (November 2009): 427–34. https://doi.org/10.1007/s11908-009-0062-y.Full Text Link to Item
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Balajee, S Arunmozhi, Rui Kano, John W. Baddley, Stephen A. Moser, Kieren A. Marr, Barbara D. Alexander, David Andes, et al. “Molecular identification of Aspergillus species collected for the Transplant-Associated Infection Surveillance Network.” J Clin Microbiol 47, no. 10 (October 2009): 3138–41. https://doi.org/10.1128/JCM.01070-09.Full Text Link to Item
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Pfaller, M. A., D. J. Diekema, M. A. Ghannoum, J. H. Rex, B. D. Alexander, D. Andes, S. D. Brown, et al. “Wild-type MIC distribution and epidemiological cutoff values for Aspergillus fumigatus and three triazoles as determined by the Clinical and Laboratory Standards Institute broth microdilution methods.” J Clin Microbiol 47, no. 10 (October 2009): 3142–46. https://doi.org/10.1128/JCM.00940-09.Full Text Link to Item
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Shi, Shuai, Elizabeth S Dodds Ashley, Barbara D. Alexander, and Anthony J. Hickey. “Initial characterization of micafungin pulmonary delivery via two different nebulizers and multivariate data analysis of aerosol mass distribution profiles.” Aaps Pharmscitech 10, no. 1 (2009): 129–37. https://doi.org/10.1208/s12249-009-9185-6.Full Text Link to Item
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Ostrosky-Zeichner, Luis, John H. Rex, Michael A. Pfaller, Daniel J. Diekema, Barbara D. Alexander, David Andes, Steven D. Brown, et al. “Rationale for reading fluconazole MICs at 24 hours rather than 48 hours when testing Candida spp. by the CLSI M27-A2 standard method.” Antimicrob Agents Chemother 52, no. 11 (November 2008): 4175–77. https://doi.org/10.1128/AAC.00420-08.Full Text Link to Item
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Alexander, Barbara D., John R. Perfect, Jennifer S. Daly, Angela Restrepo, Angela M. Tobón, Hernando Patino, Catherine J. Hardalo, and John R. Graybill. “Posaconazole as salvage therapy in patients with invasive fungal infections after solid organ transplant.” Transplantation 86, no. 6 (September 27, 2008): 791–96. https://doi.org/10.1097/TP.0b013e3181837585.Full Text Link to Item
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Singh, Nina, Olivier Lortholary, Françoise Dromer, Barbara D. Alexander, Krishan L. Gupta, George T. John, Ramon del Busto, et al. “Central nervous system cryptococcosis in solid organ transplant recipients: clinical relevance of abnormal neuroimaging findings.” Transplantation 86, no. 5 (September 15, 2008): 647–51. https://doi.org/10.1097/TP.0b013e3181814e76.Full Text Link to Item
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Pfaller, M. A., D. J. Diekema, L. Ostrosky-Zeichner, J. H. Rex, B. D. Alexander, D. Andes, S. D. Brown, et al. “Correlation of MIC with outcome for Candida species tested against caspofungin, anidulafungin, and micafungin: analysis and proposal for interpretive MIC breakpoints.” J Clin Microbiol 46, no. 8 (August 2008): 2620–29. https://doi.org/10.1128/JCM.00566-08.Full Text Link to Item
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Alexander, B. D., E. W. Petzold, L. B. Reller, S. M. Palmer, R. D. Davis, C. W. Woods, and J. J. Lipuma. “Survival after lung transplantation of cystic fibrosis patients infected with Burkholderia cepacia complex.” Am J Transplant 8, no. 5 (May 2008): 1025–30. https://doi.org/10.1111/j.1600-6143.2008.02186.x.Full Text Link to Item
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Kontoyiannis, Dimitrios P., Russell E. Lewis, Barbara D. Alexander, Olivier Lortholary, Françoise Dromer, Krishan L. Gupta, George T. John, et al. “Calcineurin inhibitor agents interact synergistically with antifungal agents in vitro against Cryptococcus neoformans isolates: correlation with outcome in solid organ transplant recipients with cryptococcosis.” Antimicrob Agents Chemother 52, no. 2 (February 2008): 735–38. https://doi.org/10.1128/AAC.00990-07.Full Text Link to Item
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Singh, Nina, Barbara D. Alexander, Olivier Lortholary, Françoise Dromer, Krishan L. Gupta, George T. John, Ramon del Busto, et al. “Pulmonary cryptococcosis in solid organ transplant recipients: clinical relevance of serum cryptococcal antigen.” Clin Infect Dis 46, no. 2 (January 15, 2008): e12–18. https://doi.org/10.1086/524738.Full Text Link to Item
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Shepard, Janeen R., Rachel M. Addison, Barbara D. Alexander, Phyllis Della-Latta, Michael Gherna, Gerhard Haase, Gerri Hall, et al. “Multicenter evaluation of the Candida albicans/Candida glabrata peptide nucleic acid fluorescent in situ hybridization method for simultaneous dual-color identification of C. albicans and C. glabrata directly from blood culture bottles.” J Clin Microbiol 46, no. 1 (January 2008): 50–55. https://doi.org/10.1128/JCM.01385-07.Full Text Link to Item
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Cohen-Wolkowiez, Michael, Daniel K. Benjamin, Vance G. Fowler, Kelly C. Wade, Barbara D. Alexander, Gordon Worley, Ricki F. Goldstein, and P Brian Smith. “Mortality and neurodevelopmental outcome after Staphylococcus aureus bacteremia in infants.” Pediatr Infect Dis J 26, no. 12 (December 2007): 1159–61. https://doi.org/10.1097/INF.0b013e31814620a6.Full Text Link to Item
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Gellad, Z. F., B. D. Alexander, J. K. Liu, B. C. Griffith, A. M. Meyer, J. L. Johnson, and A. J. Muir. “Severity of Clostridium difficile-associated diarrhea in solid organ transplant patients.” Transpl Infect Dis 9, no. 4 (December 2007): 276–80. https://doi.org/10.1111/j.1399-3062.2007.00255.x.Full Text Link to Item
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Bressler, Adam M., Keith S. Kaye, John J. LiPuma, Barbara D. Alexander, Christopher M. Moore, L Barth Reller, and Christopher W. Woods. “Risk factors for Burkholderia cepacia complex bacteremia among intensive care unit patients without cystic fibrosis: a case-control study.” Infect Control Hosp Epidemiol 28, no. 8 (August 2007): 951–58. https://doi.org/10.1086/519177.Full Text Link to Item
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Smith, P Brian, Daniel K. Benjamin, Barbara D. Alexander, Melissa D. Johnson, Malcolm A. Finkelman, and William J. Steinbach. “Quantification of 1,3-beta-D-glucan levels in children: preliminary data for diagnostic use of the beta-glucan assay in a pediatric setting.” Clin Vaccine Immunol 14, no. 7 (July 2007): 924–25. https://doi.org/10.1128/CVI.00025-07.Full Text Link to Item
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Steinbach, William J., Rachel M. Addison, Lisa McLaughlin, Quincy Gerrald, Paul L. Martin, Timothy Driscoll, Christopher Bentsen, John R. Perfect, and Barbara D. Alexander. “Prospective Aspergillus galactomannan antigen testing in pediatric hematopoietic stem cell transplant recipients.” Pediatr Infect Dis J 26, no. 7 (July 2007): 558–64. https://doi.org/10.1097/INF.0b013e3180616cbb.Full Text Link to Item
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Hanson, Kimberly E., L Barth Reller, Joanne Kurtzberg, Mitchell Horwitz, Gwynn Long, and Barbara D. Alexander. “Comparison of the Digene Hybrid Capture System Cytomegalovirus (CMV) DNA (version 2.0), Roche CMV UL54 analyte-specific reagent, and QIAGEN RealArt CMV LightCycler PCR reagent tests using AcroMetrix OptiQuant CMV DNA quantification panels and specimens from allogeneic-stem-cell transplant recipients.” J Clin Microbiol 45, no. 6 (June 2007): 1972–73. https://doi.org/10.1128/JCM.02515-06.Full Text Link to Item
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Ostrosky-Zeichner, L., C. Sable, J. Sobel, B. D. Alexander, G. Donowitz, V. Kan, C. A. Kauffman, et al. “Multicenter retrospective development and validation of a clinical prediction rule for nosocomial invasive candidiasis in the intensive care setting.” Eur J Clin Microbiol Infect Dis 26, no. 4 (April 2007): 271–76. https://doi.org/10.1007/s10096-007-0270-z.Full Text Link to Item
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Alexander, Barbara D., Terry C. Byrne, Kelly L. Smith, Kimberly E. Hanson, Kevin J. Anstrom, John R. Perfect, and L Barth Reller. “Comparative evaluation of Etest and sensititre yeastone panels against the Clinical and Laboratory Standards Institute M27-A2 reference broth microdilution method for testing Candida susceptibility to seven antifungal agents.” J Clin Microbiol 45, no. 3 (March 2007): 698–706. https://doi.org/10.1128/JCM.01840-06.Full Text Link to Item
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Hanson, Kimberly E., Barbara D. Alexander, Christopher Woods, Cathy Petti, and L Barth Reller. “Validation of laboratory screening criteria for herpes simplex virus testing of cerebrospinal fluid.” J Clin Microbiol 45, no. 3 (March 2007): 721–24. https://doi.org/10.1128/JCM.01950-06.Full Text Link to Item
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Singh, Nina, Barbara D. Alexander, Olivier Lortholary, Francoise Dromer, Krishan L. Gupta, George T. John, Ramon del Busto, et al. “Cryptococcus neoformans in organ transplant recipients: impact of calcineurin-inhibitor agents on mortality.” J Infect Dis 195, no. 5 (March 1, 2007): 756–64. https://doi.org/10.1086/511438.Full Text Link to Item
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Cohen-Wolkowiez, M., P. B. Smith, B. Mangum, W. J. Steinbach, B. D. Alexander, C. M. Cotten, R. H. Clark, T. J. Walsh, and D. K. Benjamin. “Neonatal Candida meningitis: significance of cerebrospinal fluid parameters and blood cultures.” J Perinatol 27, no. 2 (February 2007): 97–100. https://doi.org/10.1038/sj.jp.7211628.Full Text Link to Item
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Weinberg, Jason B., Barbara D. Alexander, Joseph M. Majure, Larry W. Williams, Jason Y. Kim, Peter Vandamme, and John J. LiPuma. “Burkholderia glumae infection in an infant with chronic granulomatous disease.” J Clin Microbiol 45, no. 2 (February 2007): 662–65. https://doi.org/10.1128/JCM.02058-06.Full Text Link to Item
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Alexander, B. D., and K. Hanson. “Infections in the Transplant Recipient,” January 1, 2007, 439–59. https://doi.org/10.1002/9780470751541.ch25.Full Text
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Zaas, Aimee K., Elizabeth S. Dodds Ashley, Barbara D. Alexander, Melissa D. Johnson, and John R. Perfect. “Caspofungin for invasive candidiasis at a tertiary care medical center.” Am J Med 119, no. 11 (November 2006): 993.e1-993.e6. https://doi.org/10.1016/j.amjmed.2006.02.029.Full Text Link to Item
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Anaissie, Elias J., Brahm H. Segal, John R. Graybill, Carola Arndt, John R. Perfect, Michael Kleinberg, Peter Pappas, et al. “Clinical research in the lay press: irresponsible journalism raises a huge dose of doubt.” Clin Infect Dis 43, no. 8 (October 15, 2006): 1031–39. https://doi.org/10.1086/509116.Full Text Link to Item
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Hanson, Kimberly, and Barbara Alexander. “Strategies for the prevention of infection after solid organ transplantation.” Expert Rev Anti Infect Ther 4, no. 5 (October 2006): 837–52. https://doi.org/10.1586/14787210.4.5.837.Full Text Link to Item
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Alexander, B. D., and M. A. Pfaller. “Contemporary tools for the diagnosis and management of invasive mycoses.” Clinical Infectious Diseases 43, no. SUPPL. 1 (August 1, 2006). https://doi.org/10.1086/504491.Full Text
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Alexander, Barbara D., Elizabeth Dodds Ashley, L Barth Reller, and Shelby D. Reed. “Cost savings with implementation of PNA FISH testing for identification of Candida albicans in blood cultures.” Diagn Microbiol Infect Dis 54, no. 4 (April 2006): 277–82. https://doi.org/10.1016/j.diagmicrobio.2005.10.011.Full Text Link to Item
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Alexander, B. D., E. S. Dodds Ashley, R. M. Addison, J. A. Alspaugh, N. J. Chao, and J. R. Perfect. “Non-comparative evaluation of the safety of aerosolized amphotericin B lipid complex in patients undergoing allogeneic hematopoietic stem cell transplantation.” Transpl Infect Dis 8, no. 1 (March 2006): 13–20. https://doi.org/10.1111/j.1399-3062.2006.00125.x.Full Text Link to Item
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Costa, Sylvia F., and Barbara D. Alexander. “Non-Aspergillus fungal pneumonia in transplant recipients.” Clin Chest Med 26, no. 4 (December 2005): 675–vii. https://doi.org/10.1016/j.ccm.2005.06.001.Full Text Link to Item
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Zaas, A. K., and B. D. Alexander. “Galactomannan and advances in fungal diagnostics.” Current Opinion in Organ Transplantation 10, no. 4 (December 1, 2005): 307–11. https://doi.org/10.1097/01.mot.0000187102.18780.b0.Full Text
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Singh, Nina, Olivier Lortholary, Barbara D. Alexander, Krishan L. Gupta, George T. John, Kenneth J. Pursell, Patricia Muñoz, et al. “Antifungal management practices and evolution of infection in organ transplant recipients with cryptococcus neoformans infection.” Transplantation 80, no. 8 (October 27, 2005): 1033–39. https://doi.org/10.1097/01.tp.0000173774.74388.49.Full Text Link to Item
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Singh, Nina, Olivier Lortholary, Barbara D. Alexander, Krishan L. Gupta, George T. John, Kenneth Pursell, Patricia Munoz, et al. “Allograft loss in renal transplant recipients with cryptococcus neoformans associated immune reconstitution syndrome.” Transplantation 80, no. 8 (October 27, 2005): 1131–33. https://doi.org/10.1097/01.tp.0000180530.17683.02.Full Text Link to Item
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Razonable, Raymund R., Robert A. Brown, Atul Humar, Emma Covington, Emma Alecock, Carlos V. Paya, and Carlos V. PV16000 Study Group. “A longitudinal molecular surveillance study of human polyomavirus viremia in heart, kidney, liver, and pancreas transplant patients.” J Infect Dis 192, no. 8 (October 15, 2005): 1349–54. https://doi.org/10.1086/466532.Full Text Link to Item
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Alexander, Barbara D., Wiley A. Schell, Jackie L. Miller, Gwynn D. Long, and John R. Perfect. “Candida glabrata fungemia in transplant patients receiving voriconazole after fluconazole.” Transplantation 80, no. 6 (September 27, 2005): 868–71. https://doi.org/10.1097/01.tp.0000173771.47698.7b.Full Text Link to Item
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Ostrosky-Zeichner, Luis, Barbara D. Alexander, Daniel H. Kett, Jose Vazquez, Peter G. Pappas, Fumihiro Saeki, Paul A. Ketchum, et al. “Multicenter clinical evaluation of the (1-->3) beta-D-glucan assay as an aid to diagnosis of fungal infections in humans.” Clin Infect Dis 41, no. 5 (September 1, 2005): 654–59. https://doi.org/10.1086/432470.Full Text Link to Item
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Upton, Arlo, Anja Gugel, Wendy Leisenring, Ajit Limaye, Barbara Alexander, Randall Hayden, and Kieren A. Marr. “Reproducibility of low galactomannan enzyme immunoassay index values tested in multiple laboratories.” J Clin Microbiol 43, no. 9 (September 2005): 4796–4800. https://doi.org/10.1128/JCM.43.9.4796-4800.2005.Full Text Link to Item
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Zaas, Aimee K., and Barbara D. Alexander. “Echinocandins: role in antifungal therapy, 2005.” Expert Opin Pharmacother 6, no. 10 (August 2005): 1657–68. https://doi.org/10.1517/14656566.6.10.1657.Full Text Link to Item
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Singh, Nina, Olivier Lortholary, Barbara D. Alexander, Krishan L. Gupta, George T. John, Kenneth Pursell, Patricia Munoz, et al. “An immune reconstitution syndrome-like illness associated with Cryptococcus neoformans infection in organ transplant recipients.” Clin Infect Dis 40, no. 12 (June 15, 2005): 1756–61. https://doi.org/10.1086/430606.Full Text Link to Item
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Wiltshire, Hugh, Carlos V. Paya, Mark D. Pescovitz, Atul Humar, Edward Dominguez, Kenneth Washburn, Emily Blumberg, et al. “Pharmacodynamics of oral ganciclovir and valganciclovir in solid organ transplant recipients.” Transplantation 79, no. 11 (June 15, 2005): 1477–83. https://doi.org/10.1097/01.tp.0000164512.99703.ad.Full Text Link to Item
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Dodds Ashley, Elizabeth S., and Barbara D. Alexander. “Posaconazole.” Drugs Today (Barc) 41, no. 6 (June 2005): 393–400. https://doi.org/10.1358/dot.2005.41.6.898145.Full Text Link to Item
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Wilson, D. A., M. J. Joyce, L. S. Hall, L. B. Reller, G. D. Roberts, G. S. Hall, B. D. Alexander, and G. W. Procop. “Multicenter evaluation of a Candida albicans peptide nucleic acid fluorescent in situ hybridization probe for characterization of yeast isolates from blood cultures.” J Clin Microbiol 43, no. 6 (June 2005): 2909–12. https://doi.org/10.1128/JCM.43.6.2909-2912.2005.Full Text Link to Item
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Alexander, Barbara D., and John R. Wingard. “Study of renal safety in amphotericin B lipid complex-treated patients.” Clin Infect Dis 40 Suppl 6 (May 1, 2005): S414–21. https://doi.org/10.1086/429335.Full Text Link to Item
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Alexander, Bruce D., and Trevor J. Dines. “Chemical interactions in the surface-enhanced resonance Raman scattering of ruthenium polypyridyl complexes.” J Phys Chem B 109, no. 8 (March 3, 2005): 3310–18. https://doi.org/10.1021/jp0485690.Full Text Link to Item
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Alexander, Barbara D. “Cryptococcosis after solid organ transplantation.” Transpl Infect Dis 7, no. 1 (March 2005): 1–3. https://doi.org/10.1111/j.1399-3062.2005.00079.x.Full Text Link to Item
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Blankenship, Jill R., Nina Singh, Barbara D. Alexander, and Joseph Heitman. “Cryptococcus neoformans isolates from transplant recipients are not selected for resistance to calcineurin inhibitors by current immunosuppressive regimens.” J Clin Microbiol 43, no. 1 (January 2005): 464–67. https://doi.org/10.1128/JCM.43.1.464-467.2005.Full Text Link to Item
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Husain, Shahid, Patricia Muñoz, Graeme Forrest, Barbara D. Alexander, Jyoti Somani, Kathleen Brennan, Marilyn M. Wagener, and Nina Singh. “Infections due to Scedosporium apiospermum and Scedosporium prolificans in transplant recipients: clinical characteristics and impact of antifungal agent therapy on outcome.” Clin Infect Dis 40, no. 1 (January 1, 2005): 89–99. https://doi.org/10.1086/426445.Full Text Link to Item
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Wiltshire, Hugh, Sarapee Hirankarn, Colm Farrell, Carlos Paya, Mark D. Pescovitz, Atul Humar, Edward Dominguez, et al. “Pharmacokinetic profile of ganciclovir after its oral administration and from its prodrug, valganciclovir, in solid organ transplant recipients.” Clin Pharmacokinet 44, no. 5 (2005): 495–507. https://doi.org/10.2165/00003088-200544050-00003.Full Text Link to Item
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Freeman, Richard B., Carlos Paya, Mark D. Pescovitz, Atul Humar, Ed Dominguez, Kenneth Washburn, Emily Blumberg, Barbara Alexander, Nigel Heaton, and Nigel Valganciclovir Solid Organ Transplant Study Group. “Risk factors for cytomegalovirus viremia and disease developing after prophylaxis in high-risk solid-organ transplant recipients.” Transplantation 78, no. 12 (December 27, 2004): 1765–73. https://doi.org/10.1097/01.tp.0000142619.01510.a5.Full Text Link to Item
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Zaas, Aimee K., and Barbara D. Alexander. “New developments in the diagnosis and treatment of infections in lung transplant recipients.” Respir Care Clin N Am 10, no. 4 (December 2004): 531–47. https://doi.org/10.1016/j.rcc.2004.06.001.Full Text Link to Item
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Sturgeon, Cord, Stanley P. L. Leong, and Quan-Yang Duh. “Laparoscopic surgery for melanoma metastases to the adrenal gland.” Expert Review of Anticancer Therapy 4, no. 5 (October 2004): 837–41. https://doi.org/10.1586/14737140.4.5.837.Full Text
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Boivin, Guy, Nathalie Goyette, Christian Gilbert, Noel Roberts, Katherine Macey, Carlos Paya, Mark D. Pescovitz, et al. “Absence of cytomegalovirus-resistance mutations after valganciclovir prophylaxis, in a prospective multicenter study of solid-organ transplant recipients.” J Infect Dis 189, no. 9 (May 1, 2004): 1615–18. https://doi.org/10.1086/382753.Full Text Link to Item
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Woods, Christopher W., Adam M. Bressler, John J. LiPuma, Barbara D. Alexander, Dennis A. Clements, David J. Weber, Christopher M. Moore, L Barth Reller, and Keith S. Kaye. “Virulence associated with outbreak-related strains of Burkholderia cepacia complex among a cohort of patients with bacteremia.” Clin Infect Dis 38, no. 9 (May 1, 2004): 1243–50. https://doi.org/10.1086/383313.Full Text Link to Item
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Humar, Atul, Carlos Paya, Mark D. Pescovitz, Ed Dominguez, Kenneth Washburn, Emily Blumberg, Barbara Alexander, Richard Freeman, Nigel Heaton, and Barbara Mueller. “Clinical utility of cytomegalovirus viral load testing for predicting CMV disease in D+/R- solid organ transplant recipients.” Am J Transplant 4, no. 4 (April 2004): 644–49. https://doi.org/10.1111/j.1600-6143.2004.00391.x.Full Text Link to Item
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Paya, Carlos, Atul Humar, Ed Dominguez, Kenneth Washburn, Emily Blumberg, Barbara Alexander, Richard Freeman, Nigel Heaton, Mark D. Pescovitz, and Mark D. Valganciclovir Solid Organ Transplant Study Group. “Efficacy and safety of valganciclovir vs. oral ganciclovir for prevention of cytomegalovirus disease in solid organ transplant recipients.” Am J Transplant 4, no. 4 (April 2004): 611–20. https://doi.org/10.1111/j.1600-6143.2004.00382.x.Full Text Link to Item
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Lodge, Barbara Alexander, Elizabeth Dodds Ashley, Mark P. Steele, and John R. Perfect. “Aspergillus fumigatus empyema, arthritis, and calcaneal osteomyelitis in a lung transplant patient successfully treated with posaconazole.” J Clin Microbiol 42, no. 3 (March 2004): 1376–78. https://doi.org/10.1128/JCM.42.3.1376-1378.2004.Full Text Link to Item
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Alexander, Bruce D., and Trevor J. Dines. “Ab initio calculations and normal coordinate analysis of ruthenium tris-alpha-diimine complexes.” Inorg Chem 43, no. 1 (January 12, 2004): 342–50. https://doi.org/10.1021/ic034721l.Full Text Link to Item
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Friedman, N Deborah, Neeraja B. Peterson, William T. Sumner, and Barbara D. Alexander. “Spontaneous dermal abscesses and ulcers as a result of Serratia marcescens.” J Am Acad Dermatol 49, no. 2 Suppl Case Reports (August 2003): S193–94. https://doi.org/10.1067/mjd.2003.312.Full Text Link to Item
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Husain, Shahid, Barbara D. Alexander, Patricia Munoz, Robin K. Avery, Sally Houston, Timothy Pruett, Richard Jacobs, et al. “Opportunistic mycelial fungal infections in organ transplant recipients: emerging importance of non-Aspergillus mycelial fungi.” Clin Infect Dis 37, no. 2 (July 15, 2003): 221–29. https://doi.org/10.1086/375822.Full Text Link to Item
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Stryjewski, Martin E., John J. LiPuma, Robert H. Messier, L Barth Reller, and Barbara D. Alexander. “Sepsis, multiple organ failure, and death due to Pandoraea pnomenusa infection after lung transplantation.” J Clin Microbiol 41, no. 5 (May 2003): 2255–57. https://doi.org/10.1128/JCM.41.5.2255-2257.2003.Full Text Link to Item
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Singh, Nina, Robin K. Avery, Patricia Munoz, Timothy L. Pruett, Barbara Alexander, Richard Jacobs, Jan G. Tollemar, et al. “Trends in risk profiles for and mortality associated with invasive aspergillosis among liver transplant recipients.” Clin Infect Dis 36, no. 1 (January 1, 2003): 46–52. https://doi.org/10.1086/345441.Full Text Link to Item
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Alexander, Barbara D. “Prophylaxis of invasive mycoses in solid organ transplantation.” Curr Opin Infect Dis 15, no. 6 (December 2002): 583–89. https://doi.org/10.1097/00001432-200212000-00005.Full Text Link to Item
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Alexander, B. D. “Diagnosis of fungal infection: new technologies for the mycology laboratory.” Transpl Infect Dis 4 Suppl 3 (2002): 32–37. https://doi.org/10.1034/j.1399-3062.4.s3.5.x.Full Text Link to Item
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Alexander, B. D., J. E. Stout, L. B. Reller, and C. D. Hamilton. “Hospital management of tuberculosis in a region with a low incidence of tuberculosis and a high prevalence of nontuberculous mycobacteria.” Infect Control Hosp Epidemiol 22, no. 11 (November 2001): 715–17. https://doi.org/10.1086/501851.Full Text Link to Item
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Alexander, B. D., and V. F. Tapson. “Infectious complications of lung transplantation.” Transpl Infect Dis 3, no. 3 (September 2001): 128–37. https://doi.org/10.1034/j.1399-3062.2001.003003128.x.Full Text Link to Item
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Smith, S. R., D. W. Butterly, B. D. Alexander, and A. Greenberg. “Viral infections after renal transplantation.” Am J Kidney Dis 37, no. 4 (April 2001): 659–76. https://doi.org/10.1016/s0272-6386(01)80114-1.Full Text Link to Item
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Stout, J. E., J. R. McDonald, J. J. Engemann, B. D. Alexander, and C. D. Hamilton. “Conditions associated with pulmonary non-tuberculous mycobacteria (NTM) in a tertiary care hospital in the Southeastern US.” Clinical Infectious Diseases 31, no. 1 (July 1, 2000): 311–311.Link to Item
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Palmer, S. M., B. D. Alexander, L. L. Sanders, L. J. Edwards, L. B. Reller, R. D. Davis, and V. F. Tapson. “Significance of blood stream infection after lung transplantation: analysis in 176 consecutive patients.” Transplantation 69, no. 11 (June 15, 2000): 2360–66. https://doi.org/10.1097/00007890-200006150-00025.Full Text Link to Item
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Dictar, M. O., E. Maiolo, B. Alexander, N. Jacob, and M. T. Verón. “Mycoses in the transplanted patient.” Med Mycol 38 Suppl 1 (2000): 251–58.Link to Item
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Alexander, B. D., J. E. Stout, L. B. Reller, and C. D. Hamilton. “Hospital management of patients suspected of pulmonary TB in a high incidence area for MOTT.” American Journal of Respiratory and Critical Care Medicine 159, no. 3 (March 1, 1999): A304–A304.Link to Item
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Alexander, B. D., S. M. Palmer, V. F. Tapson, R. D. Davis, and L. B. Reller. “Bacteremia and fungemia in lung transplant recipients at Duke University Medical Center.” American Journal of Respiratory and Critical Care Medicine 159, no. 3 (March 1, 1999): A738–A738.Link to Item
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Alexander, B. D., and J. R. Perfect. “Antifungal resistance trends towards the year 2000. Implications for therapy and new approaches.” Drugs 54, no. 5 (November 1997): 657–78. https://doi.org/10.2165/00003495-199754050-00002.Full Text Link to Item
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Book Sections
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Fishman, J. A., S. F. Costa, and B. D. Alexander. “Infection in kidney transplant recipients.” In Kidney Transplantation - Principles and Practice, 517–38, 2019. https://doi.org/10.1016/B978-0-323-53186-3.00031-0.Full Text
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Perfect, J. R., B. D. Alexander, and W. A. Schell. “Phaeohyphomycoses (brown-black moulds).” In Essentials of Clinical Mycology: Second Edition, 305–17, 2011. https://doi.org/10.1007/978-1-4419-6640-7_17.Full Text
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Pfeiffer, Christopher D., John R. Perfect, and Barbara D. Alexander. “Current Controversies in the Treatment of Fungal Infections.” In Principles and Practice of Cancer Infectious Diseases, 301–16. Humana Press, 2011. https://doi.org/10.1007/978-1-60761-644-3_27.Full Text
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Singh, Nina, and Barbara D. Alexander. “Cryptococcosis in Transplant Recipients.” In CRYPTOCOCCUS: FROM HUMAN PATHOGEN TO MODEL YEAST, 507–14, 2011.Link to Item
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Hanson, Kimberly E., Barbara D. Alexander, and John Perfect. “Drug Resistance in Cryptococcus neoformans.” In Antimicrobial Drug Resistance, 967–85. Humana Press, 2009. https://doi.org/10.1007/978-1-60327-595-8_20.Full Text
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Conference Papers
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Heldman, M. R., O. S. Kates, A. Multani, J. M. Steinbrink, A. V. Lewis, B. D. Alexander, O. E. Beaird, et al. “A Multicenter Prospective Registry Study of Lung Transplant Recipients Hospitalized with COVID-19.” In Journal of Heart and Lung Transplantation, 40:S141–S141, 2021.Link to Item
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Steinbrink, Julie Marie, Rachel Myers, Melissa D. Johnson, Barbara D. Alexander, and Micah T. McClain. “Transcriptomic approaches elucidate novel aspects of the host immune response to candidemia.” In Journal of Immunology, Vol. 204, 2020.Link to Item
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Permpalung, N., T. Thaniyavarn, J. H. Saullo, S. Arif, R. A. Miller, J. M. Reynolds, and B. D. Alexander. “Impact of Respiratory Syncytial Virus Infection on Bronchiolitis Obliterans Syndrome in Lung Transplant Recipients.” In The Journal of Heart and Lung Transplantation, 38:S312–13. Elsevier BV, 2019. https://doi.org/10.1016/j.healun.2019.01.788.Full Text
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Messina, Julia A., Anthony D. Sung, Nelson J. Chao, and Barbara D. Alexander. “The Timing and Epidemiology of Enterococcus Faecium and E. Faecalis Bloodstream Infections (BSI) in Patients with Acute Leukemia Receiving Chemotherapy.” In Blood, Vol. 130. AMER SOC HEMATOLOGY, 2017.Link to Item
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Maziarz, E. K., A. W. Baker, C. B. Patel, P. Patel, C. A. Milano, J. N. Schroder, M. A. Daneshmand, B. D. Alexander, and C. R. Wolfe. “Invasive Mycobacterium abscessus Infection in Heart Transplant Recipients.” In Journal of Heart and Lung Transplantation, 36:S25–S25. ELSEVIER SCIENCE INC, 2017.Link to Item
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Wolfe, C. R., A. W. Baker, C. B. Patel, P. A. Patel, C. A. Milano, J. N. Schroder, M. A. Daneshmand, B. D. Alexander, and E. K. Maziarz. “Mycobacterium Abscessus Infection in Patients with Ventricular Assist Devices.” In Journal of Heart and Lung Transplantation, 36:S257–S257. ELSEVIER SCIENCE INC, 2017.Link to Item
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Lamoth, F., and B. D. Alexander. “Antifungal Susceptibility Testing to Predict Appropriate Initial Antifungal Therapy and Outcome in non-Aspergillus Invasive Mold Infections.” In Mycoses, 58:171–171. WILEY-BLACKWELL, 2015.Link to Item
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Sun, H. Y., B. D. Alexander, and Nina Singh. “Early-Onset Cryptococcosis in Solid Organ Transplant (SOT) Recipients.” In American Journal of Transplantation, 10:96–96. WILEY-BLACKWELL PUBLISHING, INC, 2010.Link to Item
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Pal, J. D., B. D. Alexander, A. J. Lodge, L. Blue, and C. A. Milano. “51: Successful Management of Pump Pocket Infections in Patients with Implanted Left Ventricular Assist Devices.” In The Journal of Heart and Lung Transplantation, 28:S82–83. Elsevier BV, 2009. https://doi.org/10.1016/j.healun.2008.11.728.Full Text
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Singh, Nina, O. Lortholary, B. D. Alexander, and S. Husain. “CNS cryptococcal lesions in solid organ transplant recipients with cryptococcosis.” In American Journal of Transplantation, 8:183–183. BLACKWELL PUBLISHING, 2008.Link to Item
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Gellad, Ziad F., Barbara D. Alexander, Jesse K. Liu, Brian C. Griffith, Angela M. Meyer, Jeff L. Johnson, and Andrew J. Muir. “Severity of Clostridium difficile Associated Diarrhea in Solid-Organ Transplant Patients.” In American Journal of Gastroenterology, 101:S198–S198. Ovid Technologies (Wolters Kluwer Health), 2006. https://doi.org/10.14309/00000434-200609001-00458.Full Text
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Razonable, Raymund R., Robert A. Brown, Atul Humar, Emma Covington, Emma Alecock, Carlos V. Paya, and Carlos V. PV16000 Study Group. “Herpesvirus infections in solid organ transplant patients at high risk of primary cytomegalovirus disease.” In J Infect Dis, 192:1331–39, 2005. https://doi.org/10.1086/466529.Full Text Link to Item
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Ashley, E. S. D., B. D. Alexander, J. R. Perfect, and R. H. Drew. “Cost-avoidance associated with infectious diseases clinical research.” In Pharmacotherapy, 23:415–415. PHARMACOTHERAPY PUBLICATIONS INC, 2003.Link to Item
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