Barbara Dudley Alexander

Barbara Dudley Alexander
Professor of Medicine

Clinical research related to infectious complications of solid organ and bone marrow transplantation, with a particular interest in the treatment and rapid diagnosis of fungal disease.

Current Appointments & Affiliations

Professor of Medicine, Medicine, Infectious Diseases, Medicine 2014
Professor of Pathology, Pathology, Clinical Science Departments 2014

Contact Information

315 Trent Drive, Hanes House, Room 163A, Durham, NC 27710
Duke Box 102359, Durham, NC 27710
alexa011@mc.duke.edu (919) 668-0789

Background
Education, Training, & Certifications
- Fellow, Infectious Diseases, Medicine, Duke University 1996 - 1998
- Medical Resident, Medicine, Duke University 1993 - 1996
- M.D., East Carolina University 1993
Duke Appointment History
- Associate Professor of Pathology, Pathology, Clinical Science Departments 2007 - 2014
- Associate Professor of Medicine, Medicine, Infectious Diseases, Medicine 2011 - 2014
- Associate Professor of Medicine, Medicine, Infectious Diseases, Medicine 2007 - 2010
- Assistant Professor of Medicine, Medicine, Infectious Diseases, Medicine 2002 - 2007
- Associate in the Department of Medicine, Medicine, Infectious Diseases, Medicine 1999 - 2002
Research
Selected Grants
- Molecular Mycology and Pathogenesis Training Program awarded by National Institutes of Health 2019 - 2024
- Transplant Infectious Diseases Interdisciplinary Research Training Grant awarded by National Institutes of Health 2018 - 2023
- Duke CTSA (KL2) awarded by National Institutes of Health 2018 - 2023
- Duke CTSA (TL1) awarded by National Institutes of Health 2018 - 2023
- Observational Disease Registry of Patients Treated with Systemic Mold-Active Triazoles 2017 - 2022
- Cidara Phase III - ReSTORE 2019 - 2022
- Scy-078-206 2019 - 2021
- F901318 - Aspergillus awarded by F2G Ltd 2019 - 2021
- Non-Interventional Registry Study of Systemic Antifungal Therapy in Adult Subjects with Invasive Mucormycosis or Invasive Aspergillosis Caused by Non-fumigatus Species 2017 - 2020
- Host-derived biomarker signatures to differentiate acute viral, bacterial, and fungal infection awarded by National Institutes of Health 2017 - 2020
- Open-Label Study to Evaluate the Efficacy and Safety of SCY-078 in Patients with Invasive Fungal Infections that are Refractory to or Intolerant of Standard Antifungal Treatment (FURII) 2016 - 2020
- SHP620-303 2017 - 2020
- Effectiveness of Posaconazole Prophylaxis in Patients with Hematological Malignancies 2017 - 2019
- GS-US-218-0108 - Upper Respiratory 2015 - 2018
- GS-US-218-1502 - Lower Respiratory 2015 - 2018
- Scynexis SCY-7802 2015 - 2017
- Institutional Training Grant in Pediatric Infectious Disease awarded by National Institutes of Health 2011 - 2016
- Activity of SCY - 078 (MK-3118), a new oral glucan synthase inhibitor, against clinical Candida isolates" 2014 - 2016
- Activity of VT1161 and VT1598 against Candida isolates clinically resistant to azole and echinocandin antifungal agents 2013 - 2016
- Longitudinal assessment of CMV and BK virus immunity in renal transplant patients awarded by National Institutes of Health 2013 - 2016
- Clinical Laboratory Diagnostics for Invasive Aspergillosis awarded by University of Florida 2010 - 2015
- Mid-Career Investigator Award: Preventing and Diagnosing Fungal Disease awarded by National Institutes of Health 2007 - 2013
- Microfluidic PCR Platform to Detect Microbial DNA awarded by National Institutes of Health 2005 - 2010
- Prevention & dx of fungal infxns in transplantation awarded by National Institutes of Health 2002 - 2007
- Mentored Clinical Research Scholar Program awarded by National Institutes of Health 2002 - 2006
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Hemmersbach-Miller, Marion, Barbara D. Alexander, Debra L. Sudan, Carl Pieper, and Kenneth E. Schmader. “Infections after kidney transplantation. Does age matter?.” Clin Transplant 33, no. 4 (April 2019). https://doi.org/10.1111/ctr.13516.
    Full Text Link to Item
  - Chung, Shimin Jasmine, Rachel Ann Miller, Nitipong Permpalung, Arthur Wakefield Baker, Louis Frederic Diehl, David Alan Rizzieri, and Barbara Dudley Alexander. “Fluoroquinolone prophylaxis reduces febrile neutropenia, bloodstream infections from mucosal translocations, and intensive care admissions in high risk hematological patients, a single center experience..” Leuk Lymphoma 60, no. 2 (February 2019): 488–92. https://doi.org/10.1080/10428194.2018.1488252.
    Full Text Link to Item
  - Mullane, Kathleen M., Drew J. Winston, Ajay Nooka, Michele I. Morris, Patrick Stiff, Michael J. Dugan, Henry Holland, et al. “A Randomized, Placebo-controlled Trial of Fidaxomicin for Prophylaxis of Clostridium difficile-associated Diarrhea in Adults Undergoing Hematopoietic Stem Cell Transplantation..” Clin Infect Dis 68, no. 2 (January 7, 2019): 196–203. https://doi.org/10.1093/cid/ciy484.
    Full Text Link to Item
  - Hemmersbach-Miller, Marion, Barbara D. Alexander, Debra L. Sudan, Carl Pieper, and Kenneth E. Schmader. “Single-center analysis of infectious complications in older adults during the first year after kidney transplantation..” Eur J Clin Microbiol Infect Dis 38, no. 1 (January 2019): 141–48. https://doi.org/10.1007/s10096-018-3405-5.
    Full Text Link to Item
  - Messina, Julia A., Cameron R. Wolfe, Marion Hemmersbach-Miller, Carmelo Milano, Jamie L. Todd, John Reynolds, Barbara D. Alexander, Wiley A. Schell, Christina A. Cuomo, and John R. Perfect. “Genomic characterization of recurrent mold infections in thoracic transplant recipients..” Transpl Infect Dis 20, no. 5 (October 2018). https://doi.org/10.1111/tid.12935.
    Full Text Link to Item
  - Messina, Julia A., Rohita Sinha, Kimberly Starr, Mehreen Arshad, Barbara D. Alexander, Nelson J. Chao, and Anthony D. Sung. “Clinical and Genomic Characterization of Recurrent Enterococcal Bloodstream Infection in Patients With Acute Leukemia..” Open Forum Infect Dis 5, no. 6 (June 2018). https://doi.org/10.1093/ofid/ofy107.
    Full Text Open Access Copy Link to Item
  - Schell, Wiley A., A. M. Jones, Katyna Borroto-Esoda, and Barbara D. Alexander. “Antifungal Activity of SCY-078 and Standard Antifungal Agents against 178 Clinical Isolates of Resistant and Susceptible Candida Species..” Antimicrob Agents Chemother 61, no. 11 (November 2017). https://doi.org/10.1128/AAC.01102-17.
    Full Text Link to Item
  - Lamoth, Frederic, Shimin J. Chung, Lauro Damonti, and Barbara D. Alexander. “Changing Epidemiology of Invasive Mold Infections in Patients Receiving Azole Prophylaxis..” Clin Infect Dis 64, no. 11 (June 1, 2017): 1619–21. https://doi.org/10.1093/cid/cix130.
    Full Text Link to Item
  - Lockhart, Shawn R., Mahmoud A. Ghannoum, and Barbara D. Alexander. “Establishment and Use of Epidemiological Cutoff Values for Molds and Yeasts by Use of the Clinical and Laboratory Standards Institute M57 Standard..” J Clin Microbiol 55, no. 5 (May 2017): 1262–68. https://doi.org/10.1128/JCM.02416-16.
    Full Text Link to Item
  - Baker, Arthur W., Sarah S. Lewis, Barbara D. Alexander, Luke F. Chen, Richard J. Wallace, Barbara A. Brown-Elliott, Pamela J. Isaacs, et al. “Two-Phase Hospital-Associated Outbreak of Mycobacterium abscessus: Investigation and Mitigation..” Clin Infect Dis 64, no. 7 (April 1, 2017): 902–11. https://doi.org/10.1093/cid/ciw877.
    Full Text Link to Item
  - Schell, W. A., A. M. Jones, E. P. Garvey, W. J. Hoekstra, R. J. Schotzinger, and B. D. Alexander. “Fungal CYP51 Inhibitors VT-1161 and VT-1129 Exhibit Strong In Vitro Activity against Candida glabrata and C. krusei Isolates Clinically Resistant to Azole and Echinocandin Antifungal Compounds..” Antimicrob Agents Chemother 61, no. 3 (March 2017). https://doi.org/10.1128/AAC.01817-16.
    Full Text Link to Item
  - Hemmersbach-Miller, M., J. Duronville, S. Sethi, S. E. Miller, D. N. Howell, N. Henshaw, B. D. Alexander, and J. K. Roberts. “Hemorrhagic Herpes Simplex Virus Type 1 Nephritis: An Unusual Cause of Acute Allograft Dysfunction..” Am J Transplant 17, no. 1 (January 2017): 287–91. https://doi.org/10.1111/ajt.14022.
    Full Text Open Access Copy Link to Item
  - Andes, David R., Nasia Safdar, John W. Baddley, Barbara Alexander, Lisa Brumble, Allison Freifeld, Susan Hadley, et al. “The epidemiology and outcomes of invasive Candida infections among organ transplant recipients in the United States: results of the Transplant-Associated Infection Surveillance Network (TRANSNET)..” Transpl Infect Dis 18, no. 6 (December 2016): 921–31. https://doi.org/10.1111/tid.12613.
    Full Text Link to Item
  - Abril, Maria K., Adam S. Barnett, Kara Wegermann, Eric Fountain, Andrew Strand, Benjamin M. Heyman, Britton A. Blough, et al. “Diagnosis of Capnocytophaga canimorsus Sepsis by Whole-Genome Next-Generation Sequencing..” Open Forum Infect Dis 3, no. 3 (September 2016). https://doi.org/10.1093/ofid/ofw144.
    Full Text Open Access Copy Link to Item
  - Sun, H. Y., B. D. Alexander, and S. Huprikar. “Erratum: Predictors of Immune Reconstitution Syndrome in Organ Transplant Recipients With Cryptococcosis: Implications for the Management of Immunosupression (Clinical Infectious Diseases (2015) 60 (36-44).” Clinical Infectious Diseases 62, no. 12 (June 15, 2016). https://doi.org/10.1093/cid/ciw246.
    Full Text
  - Lamoth, Frédéric, Lauro Damonti, and Barbara D. Alexander. “Role of Antifungal Susceptibility Testing in Non-Aspergillus Invasive Mold Infections..” J Clin Microbiol 54, no. 6 (June 2016): 1638–40. https://doi.org/10.1128/JCM.00318-16.
    Full Text Link to Item
  - Healey, Kelley R., Yanan Zhao, Winder B. Perez, Shawn R. Lockhart, Jack D. Sobel, Dimitrios Farmakiotis, Dimitrios P. Kontoyiannis, et al. “Prevalent mutator genotype identified in fungal pathogen Candida glabrata promotes multi-drug resistance..” Nat Commun 7 (March 29, 2016). https://doi.org/10.1038/ncomms11128.
    Full Text Link to Item
  - Husain, Shahid, Amparo Sole, Barbara D. Alexander, Saima Aslam, Robin Avery, Christian Benden, Eliane M. Billaud, et al. “The 2015 International Society for Heart and Lung Transplantation Guidelines for the management of fungal infections in mechanical circulatory support and cardiothoracic organ transplant recipients: Executive summary..” J Heart Lung Transplant 35, no. 3 (March 2016): 261–82. https://doi.org/10.1016/j.healun.2016.01.007.
    Full Text Link to Item
  - Swamydas, Muthulekha, Ji-Liang Gao, Timothy J. Break, Melissa D. Johnson, Martin Jaeger, Carlos A. Rodriguez, Jean K. Lim, et al. “CXCR1-mediated neutrophil degranulation and fungal killing promote Candida clearance and host survival..” Sci Transl Med 8, no. 322 (January 20, 2016). https://doi.org/10.1126/scitranslmed.aac7718.
    Full Text Link to Item
  - Lamoth, Frédéric, and Barbara D. Alexander. “Comparing Etest and Broth Microdilution for Antifungal Susceptibility Testing of the Most-Relevant Pathogenic Molds..” J Clin Microbiol 53, no. 10 (October 2015): 3176–81. https://doi.org/10.1128/JCM.00925-15.
    Full Text Link to Item
  - Lamoth, Frédéric, and Barbara D. Alexander. “Antifungal activities of SCY-078 (MK-3118) and standard antifungal agents against clinical non-Aspergillus mold isolates..” Antimicrob Agents Chemother 59, no. 7 (July 2015): 4308–11. https://doi.org/10.1128/AAC.00234-15.
    Full Text Link to Item
  - McCarty, Todd P., John W. Baddley, Thomas J. Walsh, Barbara D. Alexander, Dimitrios P. Kontoyiannis, Trish M. Perl, Randall Walker, et al. “Phaeohyphomycosis in transplant recipients: Results from the Transplant Associated Infection Surveillance Network (TRANSNET)..” Med Mycol 53, no. 5 (June 2015): 440–46. https://doi.org/10.1093/mmy/myv018.
    Full Text Link to Item
  - Lamoth, Frédéric, Barbara D. Alexander, Praveen R. Juvvadi, and William J. Steinbach. “Antifungal activity of compounds targeting the Hsp90-calcineurin pathway against various mould species..” J Antimicrob Chemother 70, no. 5 (May 2015): 1408–11. https://doi.org/10.1093/jac/dku549.
    Full Text Link to Item
  - Patel, Ravi M., Sarah Kandefer, Michele C. Walsh, Edward F. Bell, Waldemar A. Carlo, Abbot R. Laptook, Pablo J. Sánchez, et al. “Causes and timing of death in extremely premature infants from 2000 through 2011..” N Engl J Med 372, no. 4 (January 22, 2015): 331–40. https://doi.org/10.1056/NEJMoa1403489.
    Full Text Link to Item
  - Brasier, Allan R., Yingxin Zhao, Heidi M. Spratt, John E. Wiktorowicz, Hyunsu Ju, L Joseph Wheat, Lindsey Baden, et al. “Improved Detection of Invasive Pulmonary Aspergillosis Arising during Leukemia Treatment Using a Panel of Host Response Proteins and Fungal Antigens..” Plos One 10, no. 11 (2015). https://doi.org/10.1371/journal.pone.0143165.
    Full Text Link to Item
  - Sun, Hsin-Yun, Barbara D. Alexander, Shirish Huprikar, Graeme N. Forrest, Didier Bruno, G Marshall Lyon, Dannah Wray, et al. “Predictors of immune reconstitution syndrome in organ transplant recipients with cryptococcosis: implications for the management of immunosuppression..” Clin Infect Dis 60, no. 1 (January 1, 2015): 36–44. https://doi.org/10.1093/cid/ciu711.
    Full Text Link to Item
  - Wheat, L Joseph, M Hong Nguyen, Barbara D. Alexander, David Denning, Angela M. Caliendo, G Marshall Lyon, Lindsey R. Baden, et al. “Reply to "Insufficient demonstration of long-term stability of Aspergillus galactomannan"..” J Clin Microbiol 52, no. 11 (November 2014). https://doi.org/10.1128/JCM.02433-14.
    Full Text Link to Item
  - Horan, J. L., J. E. Stout, and B. D. Alexander. “Hepatitis B core antibody-positive donors in cardiac transplantation: a single-center experience..” Transpl Infect Dis 16, no. 5 (October 2014): 859–63. https://doi.org/10.1111/tid.12280.
    Full Text Link to Item
  - Barker, Adam P., Jennifer L. Horan, E Susan Slechta, Barbara D. Alexander, and Kimberly E. Hanson. “Complexities associated with the molecular and proteomic identification of Paecilomyces species in the clinical mycology laboratory..” Med Mycol 52, no. 5 (July 2014): 537–45. https://doi.org/10.1093/mmy/myu001.
    Full Text Link to Item
  - Doligalski, C. T., K. Benedict, A. A. Cleveland, B. Park, G. Derado, P. G. Pappas, J. W. Baddley, D. W. Zaas, M. T. Harris, and B. D. Alexander. “Epidemiology of invasive mold infections in lung transplant recipients..” Am J Transplant 14, no. 6 (June 2014): 1328–33. https://doi.org/10.1111/ajt.12691.
    Full Text Link to Item
  - Lamoth, Frédéric, and Barbara D. Alexander. “Nonmolecular methods for the diagnosis of respiratory fungal infections..” Clin Lab Med 34, no. 2 (June 2014): 315–36. https://doi.org/10.1016/j.cll.2014.02.006.
    Full Text Link to Item
  - Wheat, L Joseph, M Hong Nguyen, Barbara D. Alexander, David Denning, Angela M. Caliendo, G Marshall Lyon, Lindsey R. Baden, et al. “Long-term stability at -20 °C of Aspergillus galactomannan in serum and bronchoalveolar lavage specimens..” J Clin Microbiol 52, no. 6 (June 2014): 2108–11. https://doi.org/10.1128/JCM.03500-13.
    Full Text Link to Item
  - Rosentul, Diana C., Theo S. Plantinga, Marius Farcas, Marije Oosting, Omar J. M. Hamza, William K. Scott, Barbara D. Alexander, et al. “Role of autophagy genetic variants for the risk of Candida infections..” Med Mycol 52, no. 4 (May 2014): 333–41. https://doi.org/10.1093/mmy/myt035.
    Full Text Link to Item
  - Kauffman, C. A., A. G. Freifeld, D. R. Andes, J. W. Baddley, L. Herwaldt, R. C. Walker, B. D. Alexander, et al. “Endemic fungal infections in solid organ and hematopoietic cell transplant recipients enrolled in the Transplant-Associated Infection Surveillance Network (TRANSNET)..” Transpl Infect Dis 16, no. 2 (April 2014): 213–24. https://doi.org/10.1111/tid.12186.
    Full Text Link to Item
  - Alexander, B. D., M. D. Johnson, C. D. Pfeiffer, C. Jiménez-Ortigosa, J. Catania, and R. Booker. “Erratum: Increasing echinocandin resistance in Candida glabrata: Clinical failure correlates with presence of FKS mutations and elevated minimum inhibitory concentrations (Clinical Infectious Diseases (2013) 56 (1724-32)).” Clinical Infectious Diseases 58, no. 5 (March 1, 2014). https://doi.org/10.1093/cid/cit956.
    Full Text
  - Lionakis, Michail S., Muthulekha Swamydas, Brett G. Fischer, Theo S. Plantinga, Melissa D. Johnson, Martin Jaeger, Nathaniel M. Green, et al. “CX3CR1-dependent renal macrophage survival promotes Candida control and host survival..” J Clin Invest 123, no. 12 (December 2013): 5035–51. https://doi.org/10.1172/JCI71307.
    Full Text Link to Item
  - Lyon, G Marshall, Deborah Abdul-Ali, Juergen Loeffler, P Lewis White, Brian Wickes, Monica L. Herrera, Barbara D. Alexander, et al. “Development and evaluation of a calibrator material for nucleic acid-based assays for diagnosing aspergillosis..” J Clin Microbiol 51, no. 7 (July 2013): 2403–5. https://doi.org/10.1128/JCM.00744-13.
    Full Text Link to Item
  - Alexander, Barbara D., Melissa D. Johnson, Christopher D. Pfeiffer, Cristina Jiménez-Ortigosa, Jelena Catania, Rachel Booker, Mariana Castanheira, Shawn A. Messer, David S. Perlin, and Michael A. Pfaller. “Increasing echinocandin resistance in Candida glabrata: clinical failure correlates with presence of FKS mutations and elevated minimum inhibitory concentrations..” Clin Infect Dis 56, no. 12 (June 2013): 1724–32. https://doi.org/10.1093/cid/cit136.
    Full Text Link to Item
  - Westervelt, Justin D., Barbara D. Alexander, Sylvia F. Costa, Sara E. Miller, David N. Howell, and Stephen R. Smith. “Detection of BK polyomavirus after kidney transplantation: a comparison of urine electron microscopy with plasma polymerase chain reaction..” Clin Transplant 27, no. 1 (January 2013): E42–48. https://doi.org/10.1111/ctr.12048.
    Full Text Link to Item
  - Dodds Ashley, Elizabeth, Richard Drew, Melissa Johnson, Robert Danna, Dominika Dabrowski, Valery Walker, Manishi Prasad, Barbara Alexander, George Papadopoulos, and John Perfect. “Cost of invasive fungal infections in the era of new diagnostics and expanded treatment options..” Pharmacotherapy 32, no. 10 (October 2012): 890–901. https://doi.org/10.1002/j.1875-9114.2012.01124.
    Full Text Link to Item
  - Schell, W. A., J. L. Benton, P. B. Smith, M. Poore, J. L. Rouse, D. J. Boles, M. D. Johnson, et al. “Evaluation of a digital microfluidic real-time PCR platform to detect DNA of Candida albicans in blood..” Eur J Clin Microbiol Infect Dis 31, no. 9 (September 2012): 2237–45. https://doi.org/10.1007/s10096-012-1561-6.
    Full Text Open Access Copy Link to Item
  - Plantinga, Theo S., Melissa D. Johnson, William K. Scott, Esther van de Vosse, Digna R. Velez Edwards, P Brian Smith, Barbara D. Alexander, et al. “Toll-like receptor 1 polymorphisms increase susceptibility to candidemia..” J Infect Dis 205, no. 6 (March 15, 2012): 934–43. https://doi.org/10.1093/infdis/jir867.
    Full Text Link to Item
  - Rosentul, D. C., T. S. Plantinga, W. K. Scott, B. D. Alexander, N. M. D. van de Geer, J. R. Perfect, B. J. Kullberg, M. D. Johnson, and M. G. Netea. “The impact of caspase-12 on susceptibility to candidemia..” Eur J Clin Microbiol Infect Dis 31, no. 3 (March 2012): 277–80. https://doi.org/10.1007/s10096-011-1307-x.
    Full Text Link to Item
  - Johnson, Melissa D., Theo S. Plantinga, Esther van de Vosse, Digna R. Velez Edwards, P Brian Smith, Barbara D. Alexander, John C. Yang, et al. “Cytokine gene polymorphisms and the outcome of invasive candidiasis: a prospective cohort study..” Clin Infect Dis 54, no. 4 (February 15, 2012): 502–10. https://doi.org/10.1093/cid/cir827.
    Full Text Link to Item
  - Hanson, Kimberly E., Christopher D. Pfeiffer, Erika D. Lease, Alfred H. Balch, Aimee K. Zaas, John R. Perfect, and Barbara D. Alexander. “β-D-glucan surveillance with preemptive anidulafungin for invasive candidiasis in intensive care unit patients: a randomized pilot study..” Plos One 7, no. 8 (2012). https://doi.org/10.1371/journal.pone.0042282.
    Full Text Link to Item
  - Lease, Erika D., and Barbara D. Alexander. “Fungal diagnostics in pneumonia..” Semin Respir Crit Care Med 32, no. 6 (December 2011): 663–72. https://doi.org/10.1055/s-0031-1295714.
    Full Text Link to Item
  - Alexander, Barbara D., Thomas P. Winkler, Shuai Shi, Elizabeth S. Dodds Ashley, and Anthony J. Hickey. “In vitro characterization of nebulizer delivery of liposomal amphotericin B aerosols..” Pharm Dev Technol 16, no. 6 (November 2011): 577–82. https://doi.org/10.3109/10837450.2011.591803.
    Full Text Link to Item
  - Park, Benjamin J., Peter G. Pappas, Kathleen A. Wannemuehler, Barbara D. Alexander, Elias J. Anaissie, David R. Andes, John W. Baddley, et al. “Invasive non-Aspergillus mold infections in transplant recipients, United States, 2001-2006..” Emerg Infect Dis 17, no. 10 (October 2011): 1855–64. https://doi.org/10.3201/eid1710.110087.
    Full Text Link to Item
  - Rosentul, Diana C., Theo S. Plantinga, Marije Oosting, William K. Scott, Digna R. Velez Edwards, P Brian Smith, Barbara D. Alexander, et al. “Genetic variation in the dectin-1/CARD9 recognition pathway and susceptibility to candidemia..” J Infect Dis 204, no. 7 (October 1, 2011): 1138–45. https://doi.org/10.1093/infdis/jir458.
    Full Text Link to Item
  - Pfeiffer, Christopher D., Gregory P. Samsa, Wiley A. Schell, L Barth Reller, John R. Perfect, and Barbara D. Alexander. “Quantitation of Candida CFU in initial positive blood cultures..” J Clin Microbiol 49, no. 8 (August 2011): 2879–83. https://doi.org/10.1128/JCM.00609-11.
    Full Text Link to Item
  - Pfaller, Michael A., David Andes, Maiken C. Arendrup, Daniel J. Diekema, Ana Espinel-Ingroff, Barbara D. Alexander, Steven D. Brown, et al. “Clinical breakpoints for voriconazole and Candida spp. revisited: review of microbiologic, molecular, pharmacodynamic, and clinical data as they pertain to the development of species-specific interpretive criteria..” Diagn Microbiol Infect Dis 70, no. 3 (July 2011): 330–43. https://doi.org/10.1016/j.diagmicrobio.2011.03.002.
    Full Text Link to Item
  - Hauser, Philippe M., Jacques Bille, Cornelia Lass-Flörl, Christian Geltner, Marta Feldmesser, Michael Levi, Hitesh Patel, et al. “Multicenter, prospective clinical evaluation of respiratory samples from subjects at risk for Pneumocystis jirovecii infection by use of a commercial real-time PCR assay..” J Clin Microbiol 49, no. 5 (May 2011): 1872–78. https://doi.org/10.1128/JCM.02390-10.
    Full Text Link to Item
  - Person, Anna K., Dimitrios P. Kontoyiannis, and Barbara D. Alexander. “Fungal infections in transplant and oncology patients..” Hematol Oncol Clin North Am 25, no. 1 (February 2011): 193–213. https://doi.org/10.1016/j.hoc.2010.11.013.
    Full Text Link to Item
  - Alexander, Barbara D., Thomas P. Winkler, Shuai Shi, Elizabeth S Dodds Ashley, and Anthony J. Hickey. “Nebulizer delivery of micafungin aerosols..” Pharmacotherapy 31, no. 1 (January 2011): 52–57. https://doi.org/10.1592/phco.31.1.52.
    Full Text Link to Item
  - Park, B. J., P. G. Pappas, K. A. Wannemuehler, B. D. Alexander, E. J. Anaissie, D. R. Andes, J. W. Baddley, et al. “Invasive non-Aspergillus mold infections in transplant recipients, United States, 2001-2006.” Emerging Infectious Diseases 17, no. 10 (January 1, 2011): 1855–64. https://doi.org/10.3201/eid1710.110087.
    Full Text
  - Alexander, Barbara D., P Brian Smith, R Duane Davis, John R. Perfect, and L Barth Reller. “The (1,3){beta}-D-glucan test as an aid to early diagnosis of invasive fungal infections following lung transplantation..” J Clin Microbiol 48, no. 11 (November 2010): 4083–88. https://doi.org/10.1128/JCM.01183-10.
    Full Text Link to Item
  - Sun, Hsin-Yun, Barbara D. Alexander, Olivier Lortholary, Francoise Dromer, Graeme N. Forrest, G Marshall Lyon, Jyoti Somani, et al. “Unrecognized pretransplant and donor‐derived cryptococcal disease in organ transplant recipients..” Clin Infect Dis 51, no. 9 (November 1, 2010): 1062–69. https://doi.org/10.1086/656584.
    Full Text Open Access Copy Link to Item
  - Osawa, Ryosuke, Barbara D. Alexander, Graeme N. Forrest, G Marshall Lyon, Jyoti Somani, Ramon del Busto, Timothy L. Pruett, et al. “Geographic differences in disease expression of cryptococcosis in solid organ transplant recipients in the United States..” Ann Transplant 15, no. 4 (October 2010): 77–83.
    Link to Item
  - Alexander, B. D., W. A. Schell, A. M. Siston, C. Y. Rao, W. A. Bower, S. A. Balajee, D. N. Howell, et al. “Fatal Apophysomyces elegans infection transmitted by deceased donor renal allografts..” Am J Transplant 10, no. 9 (September 2010): 2161–67. https://doi.org/10.1111/j.1600-6143.2010.03216.x.
    Full Text Link to Item
  - Sun, Hsin-Yun, Barbara D. Alexander, Olivier Lortholary, Francoise Dromer, Graeme N. Forrest, G Marshall Lyon, Jyoti Somani, et al. “Cutaneous cryptococcosis in solid organ transplant recipients..” Med Mycol 48, no. 6 (September 2010): 785–91. https://doi.org/10.3109/13693780903496617.
    Full Text Link to Item
  - Harrison, Elizabeth, Thomas Stalhberger, Ruth Whelan, Michele Sugrue, John R. Wingard, Barbara D. Alexander, Sarah A. Follett, Paul Bowyer, David W. Denning, and David W. Aspergillus Technology Consortium (AsTeC). “Aspergillus DNA contamination in blood collection tubes..” Diagn Microbiol Infect Dis 67, no. 4 (August 2010): 392–94. https://doi.org/10.1016/j.diagmicrobio.2010.02.028.
    Full Text Link to Item
  - Pfeiffer, Christopher D., Guillermo Garcia-Effron, Aimee K. Zaas, John R. Perfect, David S. Perlin, and Barbara D. Alexander. “Breakthrough invasive candidiasis in patients on micafungin..” J Clin Microbiol 48, no. 7 (July 2010): 2373–80. https://doi.org/10.1128/JCM.02390-09.
    Full Text Link to Item
  - Baddley, John W., David R. Andes, Kieren A. Marr, Dimitrios P. Kontoyiannis, Barbara D. Alexander, Carol A. Kauffman, Robert A. Oster, et al. “Factors associated with mortality in transplant patients with invasive aspergillosis..” Clin Infect Dis 50, no. 12 (June 15, 2010): 1559–67. https://doi.org/10.1086/652768.
    Full Text Open Access Copy Link to Item
  - Person, Anna K., Dimitrios P. Kontoyiannis, and Barbara D. Alexander. “Fungal infections in transplant and oncology patients..” Infect Dis Clin North Am 24, no. 2 (June 2010): 439–59. https://doi.org/10.1016/j.idc.2010.01.002.
    Full Text Link to Item
  - Wulff-Burchfield, Elizabeth, Wiley A. Schell, Allen E. Eckhardt, Michael G. Pollack, Zhishan Hua, Jeremy L. Rouse, Vamsee K. Pamula, et al. “Microfluidic platform versus conventional real-time polymerase chain reaction for the detection of Mycoplasma pneumoniae in respiratory specimens..” Diagn Microbiol Infect Dis 67, no. 1 (May 2010): 22–29. https://doi.org/10.1016/j.diagmicrobio.2009.12.020.
    Full Text Open Access Copy Link to Item
  - Kontoyiannis, Dimitrios P., Kieren A. Marr, Benjamin J. Park, Barbara D. Alexander, Elias J. Anaissie, Thomas J. Walsh, James Ito, et al. “Prospective surveillance for invasive fungal infections in hematopoietic stem cell transplant recipients, 2001-2006: overview of the Transplant-Associated Infection Surveillance Network (TRANSNET) Database..” Clin Infect Dis 50, no. 8 (April 15, 2010): 1091–1100. https://doi.org/10.1086/651263.
    Full Text Open Access Copy Link to Item
  - Pappas, Peter G., Barbara D. Alexander, David R. Andes, Susan Hadley, Carol A. Kauffman, Alison Freifeld, Elias J. Anaissie, et al. “Invasive fungal infections among organ transplant recipients: results of the Transplant-Associated Infection Surveillance Network (TRANSNET)..” Clin Infect Dis 50, no. 8 (April 15, 2010): 1101–11. https://doi.org/10.1086/651262.
    Full Text Open Access Copy Link to Item
  - Nowell, L., C. Moran, P. B. Smith, P. Seed, B. D. Alexander, C. M. Cotten, J. S. Wiener, and D. K. Benjamin. “Prevalence of renal anomalies after urinary tract infections in hospitalized infants less than 2 months of age..” J Perinatol 30, no. 4 (April 2010): 281–85. https://doi.org/10.1038/jp.2009.147.
    Full Text Open Access Copy Link to Item
  - Osawa, Ryosuke, Barbara D. Alexander, Olivier Lortholary, Françoise Dromer, Graeme N. Forrest, G Marshall Lyon, Jyoti Somani, et al. “Identifying predictors of central nervous system disease in solid organ transplant recipients with cryptococcosis..” Transplantation 89, no. 1 (January 15, 2010): 69–74. https://doi.org/10.1097/TP.0b013e3181bcda41.
    Full Text Link to Item
  - Sun, Hsin-Yun, Barbara D. Alexander, Olivier Lortholary, Francoise Dromer, Graeme N. Forrest, G Marshall Lyon, Jyoti Somani, et al. “Lipid formulations of amphotericin B significantly improve outcome in solid organ transplant recipients with central nervous system cryptococcosis..” Clin Infect Dis 49, no. 11 (December 1, 2009): 1721–28. https://doi.org/10.1086/647948.
    Full Text Link to Item
  - Radack, Kyle P., and Barbara D. Alexander. “Prophylaxis of invasive mycoses in solid organ transplantation..” Curr Infect Dis Rep 11, no. 6 (November 2009): 427–34.
    Link to Item
  - Balajee, S Arunmozhi, Rui Kano, John W. Baddley, Stephen A. Moser, Kieren A. Marr, Barbara D. Alexander, David Andes, et al. “Molecular identification of Aspergillus species collected for the Transplant-Associated Infection Surveillance Network..” J Clin Microbiol 47, no. 10 (October 2009): 3138–41. https://doi.org/10.1128/JCM.01070-09.
    Full Text Link to Item
  - Pfaller, M. A., D. J. Diekema, M. A. Ghannoum, J. H. Rex, B. D. Alexander, D. Andes, S. D. Brown, et al. “Wild-type MIC distribution and epidemiological cutoff values for Aspergillus fumigatus and three triazoles as determined by the Clinical and Laboratory Standards Institute broth microdilution methods..” J Clin Microbiol 47, no. 10 (October 2009): 3142–46. https://doi.org/10.1128/JCM.00940-09.
    Full Text Link to Item
  - Shi, Shuai, Elizabeth S Dodds Ashley, Barbara D. Alexander, and Anthony J. Hickey. “Initial characterization of micafungin pulmonary delivery via two different nebulizers and multivariate data analysis of aerosol mass distribution profiles..” Aaps Pharmscitech 10, no. 1 (2009): 129–37. https://doi.org/10.1208/s12249-009-9185-6.
    Full Text Link to Item
  - Ostrosky-Zeichner, Luis, John H. Rex, Michael A. Pfaller, Daniel J. Diekema, Barbara D. Alexander, David Andes, Steven D. Brown, et al. “Rationale for reading fluconazole MICs at 24 hours rather than 48 hours when testing Candida spp. by the CLSI M27-A2 standard method..” Antimicrob Agents Chemother 52, no. 11 (November 2008): 4175–77. https://doi.org/10.1128/AAC.00420-08.
    Full Text Link to Item
  - Alexander, Barbara D., John R. Perfect, Jennifer S. Daly, Angela Restrepo, Angela M. Tobón, Hernando Patino, Catherine J. Hardalo, and John R. Graybill. “Posaconazole as salvage therapy in patients with invasive fungal infections after solid organ transplant..” Transplantation 86, no. 6 (September 27, 2008): 791–96. https://doi.org/10.1097/TP.0b013e3181837585.
    Full Text Link to Item
  - Singh, Nina, Olivier Lortholary, Françoise Dromer, Barbara D. Alexander, Krishan L. Gupta, George T. John, Ramon del Busto, et al. “Central nervous system cryptococcosis in solid organ transplant recipients: clinical relevance of abnormal neuroimaging findings..” Transplantation 86, no. 5 (September 15, 2008): 647–51. https://doi.org/10.1097/TP.0b013e3181814e76.
    Full Text Link to Item
  - Pfaller, M. A., D. J. Diekema, L. Ostrosky-Zeichner, J. H. Rex, B. D. Alexander, D. Andes, S. D. Brown, et al. “Correlation of MIC with outcome for Candida species tested against caspofungin, anidulafungin, and micafungin: analysis and proposal for interpretive MIC breakpoints..” J Clin Microbiol 46, no. 8 (August 2008): 2620–29. https://doi.org/10.1128/JCM.00566-08.
    Full Text Link to Item
  - Alexander, B. D., E. W. Petzold, L. B. Reller, S. M. Palmer, R. D. Davis, C. W. Woods, and J. J. Lipuma. “Survival after lung transplantation of cystic fibrosis patients infected with Burkholderia cepacia complex..” Am J Transplant 8, no. 5 (May 2008): 1025–30. https://doi.org/10.1111/j.1600-6143.2008.02186.x.
    Full Text Link to Item
  - Kontoyiannis, Dimitrios P., Russell E. Lewis, Barbara D. Alexander, Olivier Lortholary, Françoise Dromer, Krishan L. Gupta, George T. John, et al. “Calcineurin inhibitor agents interact synergistically with antifungal agents in vitro against Cryptococcus neoformans isolates: correlation with outcome in solid organ transplant recipients with cryptococcosis..” Antimicrob Agents Chemother 52, no. 2 (February 2008): 735–38. https://doi.org/10.1128/AAC.00990-07.
    Full Text Link to Item
  - Singh, Nina, Barbara D. Alexander, Olivier Lortholary, Françoise Dromer, Krishan L. Gupta, George T. John, Ramon del Busto, et al. “Pulmonary cryptococcosis in solid organ transplant recipients: clinical relevance of serum cryptococcal antigen..” Clin Infect Dis 46, no. 2 (January 15, 2008): e12–18. https://doi.org/10.1086/524738.
    Full Text Link to Item
  - Shepard, Janeen R., Rachel M. Addison, Barbara D. Alexander, Phyllis Della-Latta, Michael Gherna, Gerhard Haase, Gerri Hall, et al. “Multicenter evaluation of the Candida albicans/Candida glabrata peptide nucleic acid fluorescent in situ hybridization method for simultaneous dual-color identification of C. albicans and C. glabrata directly from blood culture bottles..” J Clin Microbiol 46, no. 1 (January 2008): 50–55. https://doi.org/10.1128/JCM.01385-07.
    Full Text Link to Item
  - Alexander, B. D., and K. Hanson. “Infections in the Transplant Recipient,” December 13, 2007, 439–59. https://doi.org/10.1002/9780470751541.ch25.
    Full Text
  - Cohen-Wolkowiez, Michael, Daniel K. Benjamin, Vance G. Fowler, Kelly C. Wade, Barbara D. Alexander, Gordon Worley, Ricki F. Goldstein, and P Brian Smith. “Mortality and neurodevelopmental outcome after Staphylococcus aureus bacteremia in infants..” Pediatr Infect Dis J 26, no. 12 (December 2007): 1159–61. https://doi.org/10.1097/INF.0b013e31814620a6.
    Full Text Link to Item
  - Gellad, Z. F., B. D. Alexander, J. K. Liu, B. C. Griffith, A. M. Meyer, J. L. Johnson, and A. J. Muir. “Severity of Clostridium difficile-associated diarrhea in solid organ transplant patients..” Transpl Infect Dis 9, no. 4 (December 2007): 276–80. https://doi.org/10.1111/j.1399-3062.2007.00255.x.
    Full Text Link to Item
  - Bressler, Adam M., Keith S. Kaye, John J. LiPuma, Barbara D. Alexander, Christopher M. Moore, L Barth Reller, and Christopher W. Woods. “Risk factors for Burkholderia cepacia complex bacteremia among intensive care unit patients without cystic fibrosis: a case-control study..” Infect Control Hosp Epidemiol 28, no. 8 (August 2007): 951–58. https://doi.org/10.1086/519177.
    Full Text Link to Item
  - Smith, P Brian, Daniel K. Benjamin, Barbara D. Alexander, Melissa D. Johnson, Malcolm A. Finkelman, and William J. Steinbach. “Quantification of 1,3-beta-D-glucan levels in children: preliminary data for diagnostic use of the beta-glucan assay in a pediatric setting..” Clin Vaccine Immunol 14, no. 7 (July 2007): 924–25. https://doi.org/10.1128/CVI.00025-07.
    Full Text Link to Item
  - Steinbach, William J., Rachel M. Addison, Lisa McLaughlin, Quincy Gerrald, Paul L. Martin, Timothy Driscoll, Christopher Bentsen, John R. Perfect, and Barbara D. Alexander. “Prospective Aspergillus galactomannan antigen testing in pediatric hematopoietic stem cell transplant recipients..” Pediatr Infect Dis J 26, no. 7 (July 2007): 558–64. https://doi.org/10.1097/INF.0b013e3180616cbb.
    Full Text Link to Item
  - Hanson, Kimberly E., L Barth Reller, Joanne Kurtzberg, Mitchell Horwitz, Gwynn Long, and Barbara D. Alexander. “Comparison of the Digene Hybrid Capture System Cytomegalovirus (CMV) DNA (version 2.0), Roche CMV UL54 analyte-specific reagent, and QIAGEN RealArt CMV LightCycler PCR reagent tests using AcroMetrix OptiQuant CMV DNA quantification panels and specimens from allogeneic-stem-cell transplant recipients..” J Clin Microbiol 45, no. 6 (June 2007): 1972–73. https://doi.org/10.1128/JCM.02515-06.
    Full Text Link to Item
  - Ostrosky-Zeichner, L., C. Sable, J. Sobel, B. D. Alexander, G. Donowitz, V. Kan, C. A. Kauffman, et al. “Multicenter retrospective development and validation of a clinical prediction rule for nosocomial invasive candidiasis in the intensive care setting..” Eur J Clin Microbiol Infect Dis 26, no. 4 (April 2007): 271–76. https://doi.org/10.1007/s10096-007-0270-z.
    Full Text Link to Item
  - Alexander, Barbara D., Terry C. Byrne, Kelly L. Smith, Kimberly E. Hanson, Kevin J. Anstrom, John R. Perfect, and L Barth Reller. “Comparative evaluation of Etest and sensititre yeastone panels against the Clinical and Laboratory Standards Institute M27-A2 reference broth microdilution method for testing Candida susceptibility to seven antifungal agents..” J Clin Microbiol 45, no. 3 (March 2007): 698–706. https://doi.org/10.1128/JCM.01840-06.
    Full Text Link to Item
  - Hanson, Kimberly E., Barbara D. Alexander, Christopher Woods, Cathy Petti, and L Barth Reller. “Validation of laboratory screening criteria for herpes simplex virus testing of cerebrospinal fluid..” J Clin Microbiol 45, no. 3 (March 2007): 721–24. https://doi.org/10.1128/JCM.01950-06.
    Full Text Link to Item
  - Singh, Nina, Barbara D. Alexander, Olivier Lortholary, Francoise Dromer, Krishan L. Gupta, George T. John, Ramon del Busto, et al. “Cryptococcus neoformans in organ transplant recipients: impact of calcineurin-inhibitor agents on mortality..” J Infect Dis 195, no. 5 (March 1, 2007): 756–64. https://doi.org/10.1086/511438.
    Full Text Link to Item
  - Cohen-Wolkowiez, M., P. B. Smith, B. Mangum, W. J. Steinbach, B. D. Alexander, C. M. Cotten, R. H. Clark, T. J. Walsh, and D. K. Benjamin. “Neonatal Candida meningitis: significance of cerebrospinal fluid parameters and blood cultures..” J Perinatol 27, no. 2 (February 2007): 97–100. https://doi.org/10.1038/sj.jp.7211628.
    Full Text Link to Item
  - Weinberg, Jason B., Barbara D. Alexander, Joseph M. Majure, Larry W. Williams, Jason Y. Kim, Peter Vandamme, and John J. LiPuma. “Burkholderia glumae infection in an infant with chronic granulomatous disease..” Journal of Clinical Microbiology 45, no. 2 (February 2007): 662–65. https://doi.org/10.1128/JCM.02058-06.
    Full Text
  - Zaas, Aimee K., Elizabeth S. Dodds Ashley, Barbara D. Alexander, Melissa D. Johnson, and John R. Perfect. “Caspofungin for invasive candidiasis at a tertiary care medical center..” Am J Med 119, no. 11 (November 2006): 993.e1-993.e6. https://doi.org/10.1016/j.amjmed.2006.02.029.
    Full Text Link to Item
  - Anaissie, Elias J., Brahm H. Segal, John R. Graybill, Carola Arndt, John R. Perfect, Michael Kleinberg, Peter Pappas, et al. “Clinical research in the lay press: irresponsible journalism raises a huge dose of doubt..” Clin Infect Dis 43, no. 8 (October 15, 2006): 1031–39. https://doi.org/10.1086/509116.
    Full Text Link to Item
  - Hanson, Kimberly, and Barbara Alexander. “Strategies for the prevention of infection after solid organ transplantation..” Expert Rev Anti Infect Ther 4, no. 5 (October 2006): 837–52. https://doi.org/10.1586/14787210.4.5.837.
    Full Text Link to Item
  - Alexander, B. D., and M. A. Pfaller. “Contemporary tools for the diagnosis and management of invasive mycoses.” Clinical Infectious Diseases 43, no. SUPPL. 1 (August 1, 2006). https://doi.org/10.1086/504491.
    Full Text
  - Alexander, Barbara D., Elizabeth Dodds Ashley, L Barth Reller, and Shelby D. Reed. “Cost savings with implementation of PNA FISH testing for identification of Candida albicans in blood cultures..” Diagn Microbiol Infect Dis 54, no. 4 (April 2006): 277–82. https://doi.org/10.1016/j.diagmicrobio.2005.10.011.
    Full Text Link to Item
  - Alexander, B. D., E. S. Dodds Ashley, R. M. Addison, J. A. Alspaugh, N. J. Chao, and J. R. Perfect. “Non-comparative evaluation of the safety of aerosolized amphotericin B lipid complex in patients undergoing allogeneic hematopoietic stem cell transplantation..” Transpl Infect Dis 8, no. 1 (March 2006): 13–20. https://doi.org/10.1111/j.1399-3062.2006.00125.x.
    Full Text Link to Item
  - Costa, Sylvia F., and Barbara D. Alexander. “Non-Aspergillus fungal pneumonia in transplant recipients..” Clin Chest Med 26, no. 4 (December 2005): 675–vii. https://doi.org/10.1016/j.ccm.2005.06.001.
    Full Text Link to Item
  - Zaas, A. K., and B. D. Alexander. “Galactomannan and advances in fungal diagnostics.” Current Opinion in Organ Transplantation 10, no. 4 (December 1, 2005): 307–11. https://doi.org/10.1097/01.mot.0000187102.18780.b0.
    Full Text
  - Singh, Nina, Olivier Lortholary, Barbara D. Alexander, Krishan L. Gupta, George T. John, Kenneth J. Pursell, Patricia Muñoz, et al. “Antifungal management practices and evolution of infection in organ transplant recipients with cryptococcus neoformans infection..” Transplantation 80, no. 8 (October 27, 2005): 1033–39.
    Link to Item
  - Singh, Nina, Olivier Lortholary, Barbara D. Alexander, Krishan L. Gupta, George T. John, Kenneth Pursell, Patricia Munoz, et al. “Allograft loss in renal transplant recipients with cryptococcus neoformans associated immune reconstitution syndrome..” Transplantation 80, no. 8 (October 27, 2005): 1131–33.
    Link to Item
  - Razonable, Raymund R., Robert A. Brown, Atul Humar, Emma Covington, Emma Alecock, Carlos V. Paya, and Carlos V. PV16000 Study Group. “A longitudinal molecular surveillance study of human polyomavirus viremia in heart, kidney, liver, and pancreas transplant patients..” J Infect Dis 192, no. 8 (October 15, 2005): 1349–54. https://doi.org/10.1086/466532.
    Full Text Link to Item
  - Alexander, Barbara D., Wiley A. Schell, Jackie L. Miller, Gwynn D. Long, and John R. Perfect. “Candida glabrata fungemia in transplant patients receiving voriconazole after fluconazole..” Transplantation 80, no. 6 (September 27, 2005): 868–71.
    Link to Item
  - Ostrosky-Zeichner, Luis, Barbara D. Alexander, Daniel H. Kett, Jose Vazquez, Peter G. Pappas, Fumihiro Saeki, Paul A. Ketchum, et al. “Multicenter clinical evaluation of the (1-->3) beta-D-glucan assay as an aid to diagnosis of fungal infections in humans..” Clin Infect Dis 41, no. 5 (September 1, 2005): 654–59. https://doi.org/10.1086/432470.
    Full Text Link to Item
  - Upton, Arlo, Anja Gugel, Wendy Leisenring, Ajit Limaye, Barbara Alexander, Randall Hayden, and Kieren A. Marr. “Reproducibility of low galactomannan enzyme immunoassay index values tested in multiple laboratories..” J Clin Microbiol 43, no. 9 (September 2005): 4796–4800. https://doi.org/10.1128/JCM.43.9.4796-4800.2005.
    Full Text Link to Item
  - Zaas, Aimee K., and Barbara D. Alexander. “Echinocandins: role in antifungal therapy, 2005..” Expert Opin Pharmacother 6, no. 10 (August 2005): 1657–68. https://doi.org/10.1517/14656566.6.10.1657.
    Full Text Link to Item
  - Singh, Nina, Olivier Lortholary, Barbara D. Alexander, Krishan L. Gupta, George T. John, Kenneth Pursell, Patricia Munoz, et al. “An immune reconstitution syndrome-like illness associated with Cryptococcus neoformans infection in organ transplant recipients..” Clin Infect Dis 40, no. 12 (June 15, 2005): 1756–61. https://doi.org/10.1086/430606.
    Full Text Link to Item
  - Wiltshire, Hugh, Carlos V. Paya, Mark D. Pescovitz, Atul Humar, Edward Dominguez, Kenneth Washburn, Emily Blumberg, et al. “Pharmacodynamics of oral ganciclovir and valganciclovir in solid organ transplant recipients..” Transplantation 79, no. 11 (June 15, 2005): 1477–83.
    Link to Item
  - Dodds Ashley, Elizabeth S., and Barbara D. Alexander. “Posaconazole..” Drugs Today (Barc) 41, no. 6 (June 2005): 393–400. https://doi.org/10.1358/dot.2005.41.6.898145.
    Full Text Link to Item
  - Wilson, D. A., M. J. Joyce, L. S. Hall, L. B. Reller, G. D. Roberts, G. S. Hall, B. D. Alexander, and G. W. Procop. “Multicenter evaluation of a Candida albicans peptide nucleic acid fluorescent in situ hybridization probe for characterization of yeast isolates from blood cultures..” J Clin Microbiol 43, no. 6 (June 2005): 2909–12. https://doi.org/10.1128/JCM.43.6.2909-2912.2005.
    Full Text Link to Item
  - Alexander, Barbara D., and John R. Wingard. “Study of renal safety in amphotericin B lipid complex-treated patients..” Clin Infect Dis 40 Suppl 6 (May 1, 2005): S414–21. https://doi.org/10.1086/429335.
    Full Text Link to Item
  - Alexander, Bruce D., and Trevor J. Dines. “Chemical interactions in the surface-enhanced resonance Raman scattering of ruthenium polypyridyl complexes..” J Phys Chem B 109, no. 8 (March 3, 2005): 3310–18. https://doi.org/10.1021/jp0485690.
    Full Text Link to Item
  - Alexander, Barbara D. “Cryptococcosis after solid organ transplantation..” Transpl Infect Dis 7, no. 1 (March 2005): 1–3. https://doi.org/10.1111/j.1399-3062.2005.00079.x.
    Full Text Link to Item
  - Blankenship, Jill R., Nina Singh, Barbara D. Alexander, and Joseph Heitman. “Cryptococcus neoformans isolates from transplant recipients are not selected for resistance to calcineurin inhibitors by current immunosuppressive regimens..” J Clin Microbiol 43, no. 1 (January 2005): 464–67. https://doi.org/10.1128/JCM.43.1.464-467.2005.
    Full Text Link to Item
  - Husain, Shahid, Patricia Muñoz, Graeme Forrest, Barbara D. Alexander, Jyoti Somani, Kathleen Brennan, Marilyn M. Wagener, and Nina Singh. “Infections due to Scedosporium apiospermum and Scedosporium prolificans in transplant recipients: clinical characteristics and impact of antifungal agent therapy on outcome..” Clin Infect Dis 40, no. 1 (January 1, 2005): 89–99. https://doi.org/10.1086/426445.
    Full Text Link to Item
  - Wiltshire, Hugh, Sarapee Hirankarn, Colm Farrell, Carlos Paya, Mark D. Pescovitz, Atul Humar, Edward Dominguez, et al. “Pharmacokinetic profile of ganciclovir after its oral administration and from its prodrug, valganciclovir, in solid organ transplant recipients..” Clin Pharmacokinet 44, no. 5 (2005): 495–507. https://doi.org/10.2165/00003088-200544050-00003.
    Full Text Link to Item
  - Freeman, Richard B., Carlos Paya, Mark D. Pescovitz, Atul Humar, Ed Dominguez, Kenneth Washburn, Emily Blumberg, Barbara Alexander, Nigel Heaton, and Nigel Valganciclovir Solid Organ Transplant Study Group. “Risk factors for cytomegalovirus viremia and disease developing after prophylaxis in high-risk solid-organ transplant recipients..” Transplantation 78, no. 12 (December 27, 2004): 1765–73.
    Link to Item
  - Zaas, Aimee K., and Barbara D. Alexander. “New developments in the diagnosis and treatment of infections in lung transplant recipients..” Respir Care Clin N Am 10, no. 4 (December 2004): 531–47. https://doi.org/10.1016/j.rcc.2004.06.001.
    Full Text Link to Item
  - Boivin, Guy, Nathalie Goyette, Christian Gilbert, Noel Roberts, Katherine Macey, Carlos Paya, Mark D. Pescovitz, et al. “Absence of cytomegalovirus-resistance mutations after valganciclovir prophylaxis, in a prospective multicenter study of solid-organ transplant recipients..” J Infect Dis 189, no. 9 (May 1, 2004): 1615–18. https://doi.org/10.1086/382753.
    Full Text Link to Item
  - Woods, Christopher W., Adam M. Bressler, John J. LiPuma, Barbara D. Alexander, Dennis A. Clements, David J. Weber, Christopher M. Moore, L Barth Reller, and Keith S. Kaye. “Virulence associated with outbreak-related strains of Burkholderia cepacia complex among a cohort of patients with bacteremia..” Clin Infect Dis 38, no. 9 (May 1, 2004): 1243–50. https://doi.org/10.1086/383313.
    Full Text Link to Item
  - Humar, Atul, Carlos Paya, Mark D. Pescovitz, Ed Dominguez, Kenneth Washburn, Emily Blumberg, Barbara Alexander, Richard Freeman, Nigel Heaton, and Barbara Mueller. “Clinical utility of cytomegalovirus viral load testing for predicting CMV disease in D+/R- solid organ transplant recipients..” Am J Transplant 4, no. 4 (April 2004): 644–49. https://doi.org/10.1111/j.1600-6143.2004.00391.x.
    Full Text Link to Item
  - Paya, Carlos, Atul Humar, Ed Dominguez, Kenneth Washburn, Emily Blumberg, Barbara Alexander, Richard Freeman, Nigel Heaton, Mark D. Pescovitz, and Mark D. Valganciclovir Solid Organ Transplant Study Group. “Efficacy and safety of valganciclovir vs. oral ganciclovir for prevention of cytomegalovirus disease in solid organ transplant recipients..” Am J Transplant 4, no. 4 (April 2004): 611–20. https://doi.org/10.1111/j.1600-6143.2004.00382.x.
    Full Text Link to Item
  - Lodge, Barbara Alexander, Elizabeth Dodds Ashley, Mark P. Steele, and John R. Perfect. “Aspergillus fumigatus empyema, arthritis, and calcaneal osteomyelitis in a lung transplant patient successfully treated with posaconazole..” J Clin Microbiol 42, no. 3 (March 2004): 1376–78. https://doi.org/10.1128/jcm.42.3.1376-1378.2004.
    Full Text Link to Item
  - Alexander, Bruce D., and Trevor J. Dines. “Ab initio calculations and normal coordinate analysis of ruthenium tris-alpha-diimine complexes..” Inorg Chem 43, no. 1 (January 12, 2004): 342–50. https://doi.org/10.1021/ic034721l.
    Full Text Link to Item
  - Friedman, N Deborah, Neeraja B. Peterson, William T. Sumner, and Barbara D. Alexander. “Spontaneous dermal abscesses and ulcers as a result of Serratia marcescens..” J Am Acad Dermatol 49, no. 2 Suppl Case Reports (August 2003): S193–94. https://doi.org/10.1067/mjd.2003.312.
    Full Text Link to Item
  - Friedman, N. D., N. B. Peterson, W. T. Sumner, and B. D. Alexander. “Spontaneous dermal abscesses and ulcers as a result of serratia marcescens.” Journal of the American Academy of Dermatology 49, no. 2 B (August 1, 2003): 193–94.
  - Husain, Shahid, Barbara D. Alexander, Patricia Munoz, Robin K. Avery, Sally Houston, Timothy Pruett, Richard Jacobs, et al. “Opportunistic mycelial fungal infections in organ transplant recipients: emerging importance of non-Aspergillus mycelial fungi..” Clin Infect Dis 37, no. 2 (July 15, 2003): 221–29. https://doi.org/10.1086/375822.
    Full Text Link to Item
  - Stryjewski, Martin E., John J. LiPuma, Robert H. Messier, L Barth Reller, and Barbara D. Alexander. “Sepsis, multiple organ failure, and death due to Pandoraea pnomenusa infection after lung transplantation..” J Clin Microbiol 41, no. 5 (May 2003): 2255–57. https://doi.org/10.1128/jcm.41.5.2255-2257.2003.
    Full Text Link to Item
  - Singh, Nina, Robin K. Avery, Patricia Munoz, Timothy L. Pruett, Barbara Alexander, Richard Jacobs, Jan G. Tollemar, et al. “Trends in risk profiles for and mortality associated with invasive aspergillosis among liver transplant recipients..” Clin Infect Dis 36, no. 1 (January 1, 2003): 46–52. https://doi.org/10.1086/345441.
    Full Text Link to Item
  - Alexander, Barbara D. “Prophylaxis of invasive mycoses in solid organ transplantation..” Curr Opin Infect Dis 15, no. 6 (December 2002): 583–89. https://doi.org/10.1097/01.qco.0000044776.05458.54.
    Full Text Link to Item
  - Alexander, B. D. “Diagnosis of fungal infection: new technologies for the mycology laboratory..” Transpl Infect Dis 4 Suppl 3 (2002): 32–37.
    Link to Item
  - Alexander, B. D., J. E. Stout, L. B. Reller, and C. D. Hamilton. “Hospital management of tuberculosis in a region with a low incidence of tuberculosis and a high prevalence of nontuberculous mycobacteria..” Infect Control Hosp Epidemiol 22, no. 11 (November 2001): 715–17. https://doi.org/10.1086/501851.
    Full Text Link to Item
  - Alexander, B. D., and V. F. Tapson. “Infectious complications of lung transplantation..” Transpl Infect Dis 3, no. 3 (September 2001): 128–37.
    Link to Item
  - Smith, S. R., D. W. Butterly, B. D. Alexander, and A. Greenberg. “Viral infections after renal transplantation..” Am J Kidney Dis 37, no. 4 (April 2001): 659–76.
    Link to Item
  - Stout, J. E., J. R. McDonald, J. J. Engemann, B. D. Alexander, and C. D. Hamilton. “Conditions associated with pulmonary non-tuberculous mycobacteria (NTM) in a tertiary care hospital in the Southeastern US.” Clinical Infectious Diseases 31, no. 1 (July 1, 2000): 311–311.
    Link to Item
  - Palmer, S. M., B. D. Alexander, L. L. Sanders, L. J. Edwards, L. B. Reller, R. D. Davis, and V. F. Tapson. “Significance of blood stream infection after lung transplantation: analysis in 176 consecutive patients..” Transplantation 69, no. 11 (June 15, 2000): 2360–66.
    Link to Item
  - Dictar, M. O., E. Maiolo, B. Alexander, N. Jacob, and M. T. Verón. “Mycoses in the transplanted patient..” Med Mycol 38 Suppl 1 (2000): 251–58.
    Link to Item
  - Alexander, B. D., J. E. Stout, L. B. Reller, and C. D. Hamilton. “Hospital management of patients suspected of pulmonary TB in a high incidence area for MOTT..” American Journal of Respiratory and Critical Care Medicine 159, no. 3 (March 1, 1999): A304–A304.
    Link to Item
  - Alexander, B. D., S. M. Palmer, V. F. Tapson, R. D. Davis, and L. B. Reller. “Bacteremia and fungemia in lung transplant recipients at Duke University Medical Center..” American Journal of Respiratory and Critical Care Medicine 159, no. 3 (March 1, 1999): A738–A738.
    Link to Item
  - Alexander, B. D., and J. R. Perfect. “Antifungal resistance trends towards the year 2000. Implications for therapy and new approaches..” Drugs 54, no. 5 (November 1997): 657–78. https://doi.org/10.2165/00003495-199754050-00002.
    Full Text Link to Item
- Book Sections
  - Perfect, J. R., B. D. Alexander, and W. A. Schell. “Phaeohyphomycoses (brown-black moulds).” In Essentials of Clinical Mycology: Second Edition, 305–17, 2011. https://doi.org/10.1007/978-1-4419-6640-7_17.
    Full Text
- Conference Papers
  - Lamoth, F., and B. D. Alexander. “Antifungal Susceptibility Testing to Predict Appropriate Initial Antifungal Therapy and Outcome in non-Aspergillus Invasive Mold Infections.” In Mycoses, 58:171–171. WILEY-BLACKWELL, 2015.
    Link to Item
  - Sun, H. Y., B. D. Alexander, and Nina Singh. “Early-Onset Cryptococcosis in Solid Organ Transplant (SOT) Recipients..” In American Journal of Transplantation, 10:96–96. WILEY-BLACKWELL PUBLISHING, INC, 2010.
    Link to Item
  - Pal, J. D., B. D. Alexander, A. J. Lodge, L. Blue, and C. A. Milano. “51: Successful Management of Pump Pocket Infections in Patients with Implanted Left Ventricular Assist Devices.” In The Journal of Heart and Lung Transplantation, 28:S82–83. Elsevier BV, 2009. https://doi.org/10.1016/j.healun.2008.11.728.
    Full Text
  - Singh, Nina, O. Lortholary, B. D. Alexander, and S. Husain. “CNS cryptococcal lesions in solid organ transplant recipients with cryptococcosis.” In American Journal of Transplantation, 8:183–183. BLACKWELL PUBLISHING, 2008.
    Link to Item
  - Gellad, Ziad F., Barbara D. Alexander, Jesse K. Liu, Brian C. Griffith, Angela M. Meyer, Jeff L. Johnson, and Andrew J. Muir. “Severity of Clostridium difficile associated diarrhea in solid-organ transplant patients.” In American Journal of Gastroenterology, 101:S198–S198. NATURE PUBLISHING GROUP, 2006.
    Link to Item
  - Ashley, E. S. D., B. D. Alexander, J. R. Perfect, and R. H. Drew. “Cost-avoidance associated with infectious diseases clinical research..” In Pharmacotherapy, 23:415–415. PHARMACOTHERAPY PUBLICATIONS INC, 2003.
    Link to Item

Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.

Education, Training, & Certifications

Duke Appointment History

Selected Grants

Selected Publications

Academic Articles

Book Sections

Conference Papers