Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Fellow, Infectious Diseases, Medicine, Duke University 1996 - 1998
  • Medical Resident, Medicine, Duke University 1993 - 1996
  • M.D., East Carolina University 1993
• 

  Duke Appointment History

  • Associate Professor of Pathology, Pathology, Clinical Science Departments 2007 - 2014
  • Associate Professor of Medicine, Medicine, Infectious Diseases, Medicine 2011 - 2014
  • Associate Professor of Medicine, Medicine, Infectious Diseases, Medicine 2007 - 2010
  • Assistant Professor of Medicine, Medicine, Infectious Diseases, Medicine 2002 - 2007
  • Associate in the Department of Medicine, Medicine, Infectious Diseases, Medicine 1999 - 2002
• Research
• 

  Selected Grants

  • Transplant Infectious Diseases Interdisciplinary Research Training Grant awarded by National Institutes of Health 2018 - 2023
  • Duke CTSA (KL2) awarded by National Institutes of Health 2018 - 2023
  • Duke CTSA (TL1) awarded by National Institutes of Health 2018 - 2023
  • Observational Disease Registry of Patients Treated with Systemic Mold-Active Triazoles awarded by Astellas Pharma Global Development, Inc 2017 - 2022
  • Non-Interventional Registry Study of Systemic Antifungal Therapy in Adult Subjects with Invasive Mucormycosis or Invasive Aspergillosis Caused by Non-fumigatus Species awarded by Astellas Pharma Global Development, Inc 2017 - 2020
  • Effectiveness of Posaconazole Prophylaxis in Patients with Hematological Malignancies awarded by Merck Sharp & Dohme 2017 - 2019
  • Molecular Mycology and Pathogenesis Training Program awarded by National Institutes of Health 2002 - 2019
  • Open-Label Study to Evaluate the Efficacy and Safety of SCY-078 in Patients with Invasive Fungal Infections that are Refractory to or Intolerant of Standard Antifungal Treatment (FURII) awarded by Scynexis Inc 2016 - 2019
  • Host-derived biomarker signatures to differentiate acute viral, bacterial, and fungal infection awarded by National Institutes of Health 2017 - 2019
  • SHP620-303 awarded by Shire Human Genetics Therapies 2017 - 2019
  • GS-US-218-0108 - Upper Respiratory awarded by Gilead Sciences, Inc. 2015 - 2018
  • GS-US-218-1502 - Lower Respiratory awarded by Gilead Sciences, Inc. 2015 - 2018
  • Scynexis SCY-7802 awarded by Scynexis Inc 2015 - 2017
  • Institutional Training Grant in Pediatric Infectious Disease awarded by National Institutes of Health 2011 - 2016
  • Activity of SCY - 078 (MK-3118), a new oral glucan synthase inhibitor, against clinical Candida isolates" awarded by Scynexis Inc 2014 - 2016
  • Activity of VT1161 and VT1598 against Candida isolates clinically resistant to azole and echinocandin antifungal agents awarded by Viamet Pharmaceuticals 2013 - 2016
  • Longitudinal assessment of CMV and BK virus immunity in renal transplant patients awarded by National Institutes of Health 2013 - 2016
  • Clinical Laboratory Diagnostics for Invasive Aspergillosis awarded by University of Florida 2010 - 2015
  • Mid-Career Investigator Award: Preventing and Diagnosing Fungal Disease awarded by National Institutes of Health 2007 - 2013
  • Microfluidic PCR Platform to Detect Microbial DNA awarded by National Institutes of Health 2005 - 2010
  • Prevention & dx of fungal infxns in transplantation awarded by National Institutes of Health 2002 - 2007
  • Mentored Clinical Research Scholar Program awarded by National Institutes of Health 2002 - 2006
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Schell, WA, Jones, AM, Borroto-Esoda, K, and Alexander, BD. "Antifungal Activity of SCY-078 and Standard Antifungal Agents against 178 Clinical Isolates of Resistant and Susceptible Candida Species." Antimicrobial Agents and Chemotherapy 61, no. 11 (November 2017).  Full Text
    • Lamoth, F, Chung, SJ, Damonti, L, and Alexander, BD. "Changing Epidemiology of Invasive Mold Infections in Patients Receiving Azole Prophylaxis." Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 64, no. 11 (June 2017): 1619-1621.  Full Text
    • Lockhart, SR, Ghannoum, MA, and Alexander, BD. "Establishment and Use of Epidemiological Cutoff Values for Molds and Yeasts by Use of the Clinical and Laboratory Standards Institute M57 Standard." Journal of Clinical Microbiology 55, no. 5 (May 2017): 1262-1268. (Review)  Full Text
    • Baker, AW, Lewis, SS, Alexander, BD, Chen, LF, Wallace, RJ, Brown-Elliott, BA, Isaacs, PJ, Pickett, LC, Patel, CB, Smith, PK, Reynolds, JM, Engel, J, Wolfe, CR, Milano, CA, Schroder, JN, Davis, RD, Hartwig, MG, Stout, JE, Strittholt, N, Maziarz, EK, Saullo, JH, Hazen, KC, Walczak, RJ, Vasireddy, R, Vasireddy, S, McKnight, CM, Anderson, DJ, and Sexton, DJ. "Two-Phase Hospital-Associated Outbreak of Mycobacterium abscessus: Investigation and Mitigation." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America 64, no. 7 (April 2017): 902-911.  Full Text
    • Schell, WA, Jones, AM, Garvey, EP, Hoekstra, WJ, Schotzinger, RJ, and Alexander, BD. "Fungal CYP51 Inhibitors VT-1161 and VT-1129 Exhibit Strong In Vitro Activity against Candida glabrata and C. krusei Isolates Clinically Resistant to Azole and Echinocandin Antifungal Compounds." Antimicrobial Agents and Chemotherapy 61, no. 3 (March 2017).  Full Text
    • Hemmersbach-Miller, M, Duronville, J, Sethi, S, Miller, SE, Howell, DN, Henshaw, N, Alexander, BD, and Roberts, JK. "Hemorrhagic Herpes Simplex Virus Type 1 Nephritis: An Unusual Cause of Acute Allograft Dysfunction." American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 17, no. 1 (January 2017): 287-291.  Full Text  Open Access Copy
    • Andes, DR, Safdar, N, Baddley, JW, Alexander, B, Brumble, L, Freifeld, A, Hadley, S, Herwaldt, L, Kauffman, C, Lyon, GM, Morrison, V, Patterson, T, Perl, T, Walker, R, Hess, T, Chiller, T, Pappas, PG, and TRANSNET Investigators, . "The epidemiology and outcomes of invasive Candida infections among organ transplant recipients in the United States: results of the Transplant-Associated Infection Surveillance Network (TRANSNET)." Transplant Infectious Disease : an Official Journal of the Transplantation Society 18, no. 6 (December 2016): 921-931.  Full Text
    • Abril, MK, Barnett, AS, Wegermann, K, Fountain, E, Strand, A, Heyman, BM, Blough, BA, Swaminathan, AC, Sharma-Kuinkel, B, Ruffin, F, Alexander, BD, McCall, CM, Costa, SF, Arcasoy, MO, Hong, DK, Blauwkamp, TA, Kertesz, M, Fowler, VG, and Kraft, BD. "Diagnosis of Capnocytophaga canimorsus Sepsis by Whole-Genome Next-Generation Sequencing." Open Forum Infectious Diseases 3, no. 3 (September 2016): ofw144-null.  Full Text  Open Access Copy
    • "Sun HY, et al (Clin Infect Dis 2015; 60:36–44)." Clinical Infectious Diseases 62, no. 12 (June 15, 2016): 1621.2-1621.  Full Text
    • Lamoth, F, Damonti, L, and Alexander, BD. "Role of Antifungal Susceptibility Testing in Non-Aspergillus Invasive Mold Infections." Journal of Clinical Microbiology 54, no. 6 (June 2016): 1638-1640.  Full Text
    • Healey, KR, Zhao, Y, Perez, WB, Lockhart, SR, Sobel, JD, Farmakiotis, D, Kontoyiannis, DP, Sanglard, D, Taj-Aldeen, SJ, Alexander, BD, Jimenez-Ortigosa, C, Shor, E, and Perlin, DS. "Prevalent mutator genotype identified in fungal pathogen Candida glabrata promotes multi-drug resistance." Nature Communications 7 (March 29, 2016): 11128-null.  Full Text
    • Husain, S, Sole, A, Alexander, BD, Aslam, S, Avery, R, Benden, C, Billaud, EM, Chambers, D, Danziger-Isakov, L, Fedson, S, Gould, K, Gregson, A, Grossi, P, Hadjiliadis, D, Hopkins, P, Luong, M-L, Marriott, DJE, Monforte, V, Muñoz, P, Pasqualotto, AC, Roman, A, Silveira, FP, Teuteberg, J, Weigt, S, Zaas, AK, Zuckerman, A, and Morrissey, O. "The 2015 International Society for Heart and Lung Transplantation Guidelines for the management of fungal infections in mechanical circulatory support and cardiothoracic organ transplant recipients: Executive summary." The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation 35, no. 3 (March 2016): 261-282.  Full Text
    • Swamydas, M, Gao, J-L, Break, TJ, Johnson, MD, Jaeger, M, Rodriguez, CA, Lim, JK, Green, NM, Collar, AL, Fischer, BG, Lee, C-CR, Perfect, JR, Alexander, BD, Kullberg, B-J, Netea, MG, Murphy, PM, and Lionakis, MS. "CXCR1-mediated neutrophil degranulation and fungal killing promote Candida clearance and host survival." Science Translational Medicine 8, no. 322 (January 2016): 322ra10-null.  Full Text
    • Lamoth, F, and Alexander, BD. "Comparing Etest and Broth Microdilution for Antifungal Susceptibility Testing of the Most-Relevant Pathogenic Molds." Journal of Clinical Microbiology 53, no. 10 (October 2015): 3176-3181.  Full Text
    • Lamoth, F, and Alexander, BD. "Antifungal activities of SCY-078 (MK-3118) and standard antifungal agents against clinical non-Aspergillus mold isolates." Antimicrobial Agents and Chemotherapy 59, no. 7 (July 2015): 4308-4311.  Full Text
    • McCarty, TP, Baddley, JW, Walsh, TJ, Alexander, BD, Kontoyiannis, DP, Perl, TM, Walker, R, Patterson, TF, Schuster, MG, Lyon, GM, Wingard, JR, Andes, DR, Park, BJ, Brandt, ME, Pappas, PG, and TRANSNET Investigators, . "Phaeohyphomycosis in transplant recipients: Results from the Transplant Associated Infection Surveillance Network (TRANSNET)." Medical mycology 53, no. 5 (June 2015): 440-446.  Full Text
    • Lamoth, F, Alexander, BD, Juvvadi, PR, and Steinbach, WJ. "Antifungal activity of compounds targeting the Hsp90-calcineurin pathway against various mould species." The Journal of Antimicrobial Chemotherapy 70, no. 5 (May 2015): 1408-1411.  Full Text
    • Brasier, AR, Zhao, Y, Spratt, HM, Wiktorowicz, JE, Ju, H, Wheat, LJ, Baden, L, Stafford, S, Wu, Z, Issa, N, Caliendo, AM, Denning, DW, Soman, K, Clancy, CJ, Nguyen, MH, Sugrue, MW, Alexander, BD, and Wingard, JR. "Improved Detection of Invasive Pulmonary Aspergillosis Arising during Leukemia Treatment Using a Panel of Host Response Proteins and Fungal Antigens." Plos One 10, no. 11 (January 2015): e0143165-null.  Full Text
    • Patel, RM, Kandefer, S, Walsh, MC, Bell, EF, Carlo, WA, Laptook, AR, Sánchez, PJ, Shankaran, S, Van Meurs, KP, Ball, MB, Hale, EC, Newman, NS, Das, A, Higgins, RD, Stoll, BJ, and Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network, . "Causes and timing of death in extremely premature infants from 2000 through 2011." The New England Journal of Medicine 372, no. 4 (January 2015): 331-340.  Full Text
    • Sun, H-Y, Alexander, BD, Huprikar, S, Forrest, GN, Bruno, D, Lyon, GM, Wray, D, Johnson, LB, Sifri, CD, Razonable, RR, Morris, MI, Stosor, V, Wagener, MM, and Singh, N. "Predictors of immune reconstitution syndrome in organ transplant recipients with cryptococcosis: implications for the management of immunosuppression." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America 60, no. 1 (January 2015): 36-44.  Full Text
    • Wheat, LJ, Nguyen, MH, Alexander, BD, Denning, D, Caliendo, AM, Lyon, GM, Baden, LR, Marty, FM, Clancy, C, Kirsch, E, Noth, P, Witt, J, Sugrue, M, and Wingard, JR. "Reply to "Insufficient demonstration of long-term stability of Aspergillus galactomannan"." Journal of Clinical Microbiology 52, no. 11 (November 2014): 4119-null. (Letter)  Full Text
    • Horan, JL, Stout, JE, and Alexander, BD. "Hepatitis B core antibody-positive donors in cardiac transplantation: a single-center experience." Transplant infectious disease : an official journal of the Transplantation Society 16, no. 5 (October 2014): 859-863.  Full Text
    • Horan, JL, Stout, JE, and Alexander, BD. "Hepatitis B core antibody-positive donors in cardiac transplantation: A single-center experience." Transplant Infectious Disease 16, no. 5 (October 1, 2014): 859-863.  Full Text
    • Barker, AP, Horan, JL, Slechta, ES, Alexander, BD, and Hanson, KE. "Complexities associated with the molecular and proteomic identification of Paecilomyces species in the clinical mycology laboratory." Medical mycology 52, no. 5 (July 2014): 537-545.  Full Text
    • Doligalski, CT, Benedict, K, Cleveland, AA, Park, B, Derado, G, Pappas, PG, Baddley, JW, Zaas, DW, Harris, MT, and Alexander, BD. "Epidemiology of invasive mold infections in lung transplant recipients." American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons 14, no. 6 (June 2014): 1328-1333.  Full Text
    • Lamoth, F, and Alexander, BD. "Nonmolecular methods for the diagnosis of respiratory fungal infections." Clinics in laboratory medicine 34, no. 2 (June 2014): 315-336. (Review)  Full Text
    • Wheat, LJ, Nguyen, MH, Alexander, BD, Denning, D, Caliendo, AM, Lyon, GM, Baden, LR, Marty, FM, Clancy, C, Kirsch, E, Noth, P, Witt, J, Sugrue, M, and Wingard, JR. "Long-term stability at -20 °C of Aspergillus galactomannan in serum and bronchoalveolar lavage specimens." Journal of Clinical Microbiology 52, no. 6 (June 2014): 2108-2111.  Full Text
    • Rosentul, DC, Plantinga, TS, Farcas, M, Oosting, M, Hamza, OJM, Scott, WK, Alexander, BD, Yang, JC, Laird, GM, Joosten, LAB, van der Meer, JWM, Perfect, JR, Kullberg, B-J, van der Ven, AJAM, Johnson, MD, and Netea, MG. "Role of autophagy genetic variants for the risk of Candida infections." Medical Mycology 52, no. 4 (May 2014): 333-341.  Full Text
    • Kauffman, CA, Freifeld, AG, Andes, DR, Baddley, JW, Herwaldt, L, Walker, RC, Alexander, BD, Anaissie, EJ, Benedict, K, Ito, JI, Knapp, KM, Lyon, GM, Marr, KA, Morrison, VA, Park, BJ, Patterson, TF, Schuster, MG, Chiller, TM, and Pappas, PG. "Endemic fungal infections in solid organ and hematopoietic cell transplant recipients enrolled in the Transplant-Associated Infection Surveillance Network (TRANSNET)." Transplant Infectious Disease : an Official Journal of the Transplantation Society 16, no. 2 (April 2014): 213-224.  Full Text
    • Kauffman, CA, Freifeld, AG, Andes, DR, Baddley, JW, Herwaldt, L, Walker, RC, Alexander, BD, Anaissie, EJ, Benedict, K, Ito, JI, Knapp, KM, Lyon, GM, Marr, KA, Morrison, VA, Park, BJ, Patterson, TF, Schuster, MG, Chiller, TM, and Pappas, PG. "Endemic fungal infections in solid organ and hematopoietic cell transplant recipients enrolled in the Transplant-Associated Infection Surveillance Network (TRANSNET)." Transplant Infectious Disease 16, no. 2 (April 2014): 213-224.  Full Text
    • "Alexander et al (Clin Infect Dis 2013; 56:1724-s32)." Clinical Infectious Diseases 58, no. 5 (March 1, 2014): 754-754.  Full Text
    • Doligalski, CT, Benedict, K, Cleveland, AA, Park, B, Derado, G, Pappas, PG, Baddley, JW, Zaas, DW, Harris, MT, and Alexander, BD. "Epidemiology of invasive mold infections in lung transplant recipients." American Journal of Transplantation 14, no. 6 (January 1, 2014): 1328-1333.  Full Text
    • Lamoth, F, and Alexander, BD. "Nonmolecular methods for the diagnosis of respiratory fungal infections." Clinics in Laboratory Medicine 34, no. 2 (January 1, 2014): 315-336. (Review)  Full Text
    • Lionakis, MS, Swamydas, M, Fischer, BG, Plantinga, TS, Johnson, MD, Jaeger, M, Green, NM, Masedunskas, A, Weigert, R, Mikelis, C, Wan, W, Lee, C-CR, Lim, JK, Rivollier, A, Yang, JC, Laird, GM, Wheeler, RT, Alexander, BD, Perfect, JR, Gao, J-L, Kullberg, B-J, Netea, MG, and Murphy, PM. "CX3CR1-dependent renal macrophage survival promotes Candida control and host survival." The Journal of Clinical Investigation 123, no. 12 (December 2013): 5035-5051.  Full Text
    • Lyon, GM, Abdul-Ali, D, Loeffler, J, White, PL, Wickes, B, Herrera, ML, Alexander, BD, Baden, LR, Clancy, C, Denning, D, Nguyen, MH, Sugrue, M, Wheat, LJ, Wingard, JR, Donnelly, JP, Barnes, R, Patterson, TF, Caliendo, AM, AsTeC, IAAM, and EAPCRI Investigators, . "Development and evaluation of a calibrator material for nucleic acid-based assays for diagnosing aspergillosis." Journal of Clinical Microbiology 51, no. 7 (July 2013): 2403-2405.  Full Text
    • Alexander, BD, Johnson, MD, Pfeiffer, CD, Jiménez-Ortigosa, C, Catania, J, Booker, R, Castanheira, M, Messer, SA, Perlin, DS, and Pfaller, MA. "Increasing echinocandin resistance in Candida glabrata: clinical failure correlates with presence of FKS mutations and elevated minimum inhibitory concentrations." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America 56, no. 12 (June 2013): 1724-1732.  Full Text
    • Westervelt, JD, Alexander, BD, Costa, SF, Miller, SE, Howell, DN, and Smith, SR. "Detection of BK polyomavirus after kidney transplantation: a comparison of urine electron microscopy with plasma polymerase chain reaction." Clin Transplant 27, no. 1 (January 2013): E42-E48.  Full Text  Link to Item
    • Westervelt, JD, Alexander, BD, Costa, SF, Miller, SE, Howell, DN, and Smith, SR. "Detection of BK polyomavirus after kidney transplantation: A comparison of urine electron microscopy with plasma polymerase chain reaction." Clinical Transplantation 27, no. 1 (2013): E42-E48.  Full Text
    • Dodds Ashley, E, Drew, R, Johnson, M, Danna, R, Dabrowski, D, Walker, V, Prasad, M, Alexander, B, Papadopoulos, G, and Perfect, J. "Cost of invasive fungal infections in the era of new diagnostics and expanded treatment options." Pharmacotherapy 32, no. 10 (October 2012): 890-901.  Full Text  Link to Item
    • Schell, WA, Benton, JL, Smith, PB, Poore, M, Rouse, JL, Boles, DJ, Johnson, MD, Alexander, BD, Pamula, VK, Eckhardt, AE, Pollack, MG, Benjamin, DK, Perfect, JR, and Mitchell, TG. "Evaluation of a digital microfluidic real-time PCR platform to detect DNA of Candida albicans in blood." European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology 31, no. 9 (September 2012): 2237-2245.  Full Text  Open Access Copy
    • Plantinga, TS, Johnson, MD, Scott, WK, van de Vosse, E, Velez Edwards, DR, Smith, PB, Alexander, BD, Yang, JC, Kremer, D, Laird, GM, Oosting, M, Joosten, LAB, van der Meer, JWM, van Dissel, JT, Walsh, TJ, Perfect, JR, Kullberg, BJ, and Netea, MG. "Toll-like receptor 1 polymorphisms increase susceptibility to candidemia." J Infect Dis 205, no. 6 (March 15, 2012): 934-943.  Full Text  Link to Item
    • Rosentul, DC, Plantinga, TS, Scott, WK, Alexander, BD, van de Geer, NMD, Perfect, JR, Kullberg, BJ, Johnson, MD, and Netea, MG. "The impact of caspase-12 on susceptibility to candidemia." European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology 31, no. 3 (March 2012): 277-280.  Full Text
    • Johnson, MD, Plantinga, TS, van de Vosse, E, Velez Edwards, DR, Smith, PB, Alexander, BD, Yang, JC, Kremer, D, Laird, GM, Oosting, M, Joosten, LAB, van der Meer, JWM, van Dissel, JT, Walsh, TJ, Perfect, JR, Kullberg, B-J, Scott, WK, and Netea, MG. "Cytokine gene polymorphisms and the outcome of invasive candidiasis: a prospective cohort study." Clin Infect Dis 54, no. 4 (February 15, 2012): 502-510.  Full Text  Link to Item
    • Hanson, KE, Pfeiffer, CD, Lease, ED, Balch, AH, Zaas, AK, Perfect, JR, and Alexander, BD. "β-D-glucan surveillance with preemptive anidulafungin for invasive candidiasis in intensive care unit patients: a randomized pilot study." Plos One 7, no. 8 (January 2012): e42282-null.  Full Text
    • Lease, ED, and Alexander, BD. "Fungal diagnostics in pneumonia." Seminars in Respiratory and Critical Care Medicine 32, no. 6 (December 13, 2011): 663-672. (Review)  Full Text
    • Alexander, BD, Winkler, TP, Shi, S, Dodds Ashley, ES, and Hickey, AJ. "In vitro characterization of nebulizer delivery of liposomal amphotericin B aerosols." Pharmaceutical development and technology 16, no. 6 (November 2011): 577-582. (Academic Article)  Full Text
    • Park, BJ, Pappas, PG, Wannemuehler, KA, Alexander, BD, Anaissie, EJ, Andes, DR, Baddley, JW, Brown, JM, Brumble, LM, Freifeld, AG, Hadley, S, Herwaldt, L, Ito, JI, Kauffman, CA, Lyon, GM, Marr, KA, Morrison, VA, Papanicolaou, G, Patterson, TF, Perl, TM, Schuster, MG, Walker, R, Wingard, JR, Walsh, TJ, and Kontoyiannis, DP. "Invasive non-Aspergillus mold infections in transplant recipients, United States, 2001-2006." Emerging Infectious Diseases 17, no. 10 (October 2011): 1855-1864.  Full Text
    • Rosentul, DC, Plantinga, TS, Oosting, M, Scott, WK, Velez Edwards, DR, Smith, PB, Alexander, BD, Yang, JC, Laird, GM, Joosten, LAB, van der Meer, JWM, Perfect, JR, Kullberg, B-J, Netea, MG, and Johnson, MD. "Genetic variation in the dectin-1/CARD9 recognition pathway and susceptibility to candidemia." The Journal of Infectious Diseases 204, no. 7 (October 2011): 1138-1145.  Full Text
    • Pfeiffer, CD, Samsa, GP, Schell, WA, Reller, LB, Perfect, JR, and Alexander, BD. "Quantitation of Candida CFU in initial positive blood cultures." Journal of Clinical Microbiology 49, no. 8 (August 2011): 2879-2883.  Full Text
    • Pfaller, MA, Andes, D, Arendrup, MC, Diekema, DJ, Espinel-Ingroff, A, Alexander, BD, Brown, SD, Chaturvedi, V, Fowler, CL, Ghannoum, MA, Johnson, EM, Knapp, CC, Motyl, MR, Ostrosky-Zeichner, L, and Walsh, TJ. "Clinical breakpoints for voriconazole and Candida spp. revisited: review of microbiologic, molecular, pharmacodynamic, and clinical data as they pertain to the development of species-specific interpretive criteria." Diagnostic Microbiology and Infectious Disease 70, no. 3 (July 2011): 330-343. (Review)  Full Text
    • Hauser, PM, Bille, J, Lass-Flörl, C, Geltner, C, Feldmesser, M, Levi, M, Patel, H, Muggia, V, Alexander, B, Hughes, M, Follett, SA, Cui, X, Leung, F, Morgan, G, Moody, A, Perlin, DS, and Denning, DW. "Multicenter, prospective clinical evaluation of respiratory samples from subjects at risk for Pneumocystis jirovecii infection by use of a commercial real-time PCR assay." Journal of Clinical Microbiology 49, no. 5 (May 2011): 1872-1878.  Full Text
    • Person, AK, Kontoyiannis, DP, and Alexander, BD. "Fungal infections in transplant and oncology patients." Hematol Oncol Clin North Am 25, no. 1 (February 2011): 193-213.  Full Text  Link to Item
    • Alexander, BD, Winkler, TP, Shi, S, Ashley, ESD, and Hickey, AJ. "Nebulizer delivery of micafungin aerosols." Pharmacotherapy 31, no. 1 (January 2011): 52-57.  Full Text  Link to Item
    • Park, BJ, Pappas, PG, Wannemuehler, KA, Alexander, BD, Anaissie, EJ, Andes, DR, Baddley, JW, Brown, JM, Brumble, LM, Freifeld, AG, Hadley, S, Herwaldt, L, Ito, JI, Kauffman, CA, Lyon, GM, Marr, KA, Morrison, VA, Papanicolaou, G, Patterson, TF, Perl, TM, Schuster, MG, Walker, R, Wingard, JR, Walsh, TJ, and Kontoyiannis, DP. "Invasive non-Aspergillus mold infections in transplant recipients, United States, 2001-2006." Emerging Infectious Diseases 17, no. 10 (January 1, 2011): 1855-1864.  Full Text
    • Alexander, BD, Smith, PB, Davis, RD, Perfect, JR, and Reller, LB. "The (1,3){beta}-D-glucan test as an aid to early diagnosis of invasive fungal infections following lung transplantation." Journal of Clinical Microbiology 48, no. 11 (November 2010): 4083-4088.  Full Text
    • Sun, H-Y, Alexander, BD, Lortholary, O, Dromer, F, Forrest, GN, Lyon, GM, Somani, J, Gupta, KL, del Busto, R, Pruett, TL, Sifri, CD, Limaye, AP, John, GT, Klintmalm, GB, Pursell, K, Stosor, V, Morris, MI, Dowdy, LA, Munoz, P, Kalil, AC, Garcia-Diaz, J, Orloff, SL, House, AA, Houston, SH, Wray, D, Huprikar, S, Johnson, LB, Humar, A, Razonable, RR, Fisher, RA, Husain, S, Wagener, MM, Singh, N, and Cryptococcal Collaborative Transplant Study Group, . "Unrecognized pretransplant and donor‐derived cryptococcal disease in organ transplant recipients." Clin Infect Dis 51, no. 9 (November 1, 2010): 1062-1069.  Full Text  Open Access Copy  Link to Item
    • Osawa, R, Alexander, BD, Forrest, GN, Lyon, GM, Somani, J, del Busto, R, Pruett, TL, Sifri, CD, Limaye, AP, Klintmalm, GB, Pursell, K, Stosor, V, Morris, MI, Dowdy, LA, Kalil, AC, Garcia-Diaz, J, Orloff, SL, Houston, SH, Wray, D, Huprikar, S, Johnson, LB, Razonable, RR, Fisher, RA, Wagener, MM, Husain, S, and Singh, N. "Geographic differences in disease expression of cryptococcosis in solid organ transplant recipients in the United States." Ann Transplant 15, no. 4 (October 2010): 77-83.  Link to Item
    • Alexander, BD, Schell, WA, Siston, AM, Rao, CY, Bower, WA, Balajee, SA, Howell, DN, Moore, ZS, Noble-Wang, J, Rhyne, JA, Fleischauer, AT, Maillard, JM, Kuehnert, M, Vikraman, D, Collins, BH, Marroquin, CE, and Park, BJ. "Fatal Apophysomyces elegans infection transmitted by deceased donor renal allografts." American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons 10, no. 9 (September 2010): 2161-2167.  Full Text
    • Sun, H-Y, Alexander, BD, Lortholary, O, Dromer, F, Forrest, GN, Lyon, GM, Somani, J, Gupta, KL, Del Busto, R, Pruett, TL, Sifri, CD, Limaye, AP, John, GT, Klintmalm, GB, Pursell, K, Stosor, V, Morris, MI, Dowdy, LA, Muñoz, P, Kalil, AC, Garcia-Diaz, J, Orloff, SL, House, AA, Houston, SH, Wray, D, Huprikar, S, Johnson, LB, Humar, A, Razonable, RR, Fisher, RA, Husain, S, Wagener, MM, Singh, N, and Cryptococcal Collaborative Transplant Study Group, . "Cutaneous cryptococcosis in solid organ transplant recipients." Med Mycol 48, no. 6 (September 2010): 785-791.  Full Text  Link to Item
    • Harrison, E, Stalhberger, T, Whelan, R, Sugrue, M, Wingard, JR, Alexander, BD, Follett, SA, Bowyer, P, Denning, DW, and Aspergillus Technology Consortium (AsTeC), . "Aspergillus DNA contamination in blood collection tubes." Diagn Microbiol Infect Dis 67, no. 4 (August 2010): 392-394.  Full Text  Link to Item
    • Pfeiffer, CD, Garcia-Effron, G, Zaas, AK, Perfect, JR, Perlin, DS, and Alexander, BD. "Breakthrough invasive candidiasis in patients on micafungin." Journal of Clinical Microbiology 48, no. 7 (July 2010): 2373-2380.  Full Text
    • Baddley, JW, Andes, DR, Marr, KA, Kontoyiannis, DP, Alexander, BD, Kauffman, CA, Oster, RA, Anaissie, EJ, Walsh, TJ, Schuster, MG, Wingard, JR, Patterson, TF, Ito, JI, Williams, OD, Chiller, T, and Pappas, PG. "Factors associated with mortality in transplant patients with invasive aspergillosis." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America 50, no. 12 (June 2010): 1559-1567.  Full Text  Open Access Copy
    • Person, AK, Kontoyiannis, DP, and Alexander, BD. "Fungal infections in transplant and oncology patients." Infectious Disease Clinics of North America 24, no. 2 (June 2010): 439-459. (Review)  Full Text
    • Wulff-Burchfield, E, Schell, WA, Eckhardt, AE, Pollack, MG, Hua, Z, Rouse, JL, Pamula, VK, Srinivasan, V, Benton, JL, Alexander, BD, Wilfret, DA, Kraft, M, Cairns, CB, Perfect, JR, and Mitchell, TG. "Microfluidic platform versus conventional real-time polymerase chain reaction for the detection of Mycoplasma pneumoniae in respiratory specimens." Diagnostic Microbiology and Infectious Disease 67, no. 1 (May 2010): 22-29.  Full Text  Open Access Copy
    • Kontoyiannis, DP, Marr, KA, Park, BJ, Alexander, BD, Anaissie, EJ, Walsh, TJ, Ito, J, Andes, DR, Baddley, JW, Brown, JM, Brumble, LM, Freifeld, AG, Hadley, S, Herwaldt, LA, Kauffman, CA, Knapp, K, Lyon, GM, Morrison, VA, Papanicolaou, G, Patterson, TF, Perl, TM, Schuster, MG, Walker, R, Wannemuehler, KA, Wingard, JR, Chiller, TM, and Pappas, PG. "Prospective surveillance for invasive fungal infections in hematopoietic stem cell transplant recipients, 2001-2006: overview of the Transplant-Associated Infection Surveillance Network (TRANSNET) Database." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America 50, no. 8 (April 2010): 1091-1100.  Full Text  Open Access Copy
    • Nowell, L, Moran, C, Smith, PB, Seed, P, Alexander, BD, Cotten, CM, Wiener, JS, and Benjamin, DK. "Prevalence of renal anomalies after urinary tract infections in hospitalized infants less than 2 months of age." J Perinatol 30, no. 4 (April 2010): 281-285.  Full Text  Open Access Copy  Link to Item
    • Pappas, PG, Alexander, BD, Andes, DR, Hadley, S, Kauffman, CA, Freifeld, A, Anaissie, EJ, Brumble, LM, Herwaldt, L, Ito, J, Kontoyiannis, DP, Lyon, GM, Marr, KA, Morrison, VA, Park, BJ, Patterson, TF, Perl, TM, Oster, RA, Schuster, MG, Walker, R, Walsh, TJ, Wannemuehler, KA, and Chiller, TM. "Invasive fungal infections among organ transplant recipients: results of the Transplant-Associated Infection Surveillance Network (TRANSNET)." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America 50, no. 8 (April 2010): 1101-1111.  Full Text  Open Access Copy
    • Osawa, R, Alexander, BD, Lortholary, O, Dromer, F, Forrest, GN, Lyon, GM, Somani, J, Gupta, KL, Del Busto, R, Pruett, TL, Sifri, CD, Limaye, AP, John, GT, Klintmalm, GB, Pursell, K, Stosor, V, Morris, MI, Dowdy, LA, Muñoz, P, Kalil, AC, Garcia-Diaz, J, Orloff, S, House, AA, Houston, S, Wray, D, Huprikar, S, Johnson, LB, Humar, A, Razonable, RR, Fisher, RA, Husain, S, Wagener, MM, and Singh, N. "Identifying predictors of central nervous system disease in solid organ transplant recipients with cryptococcosis." Transplantation 89, no. 1 (January 2010): 69-74.  Full Text
    • Sun, H-Y, Alexander, BD, Lortholary, O, Dromer, F, Forrest, GN, Lyon, GM, Somani, J, Gupta, KL, del Busto, R, Pruett, TL, Sifri, CD, Limaye, AP, John, GT, Klintmalm, GB, Pursell, K, Stosor, V, Morris, MI, Dowdy, LA, Munoz, P, Kalil, AC, Garcia-Diaz, J, Orloff, S, House, AA, Houston, S, Wray, D, Huprikar, S, Johnson, LB, Humar, A, Razonable, RR, Husain, S, and Singh, N. "Lipid formulations of amphotericin B significantly improve outcome in solid organ transplant recipients with central nervous system cryptococcosis." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America 49, no. 11 (December 2009): 1721-1728.  Full Text
    • Radack, KP, and Alexander, BD. "Prophylaxis of invasive mycoses in solid organ transplantation." Curr Infect Dis Rep 11, no. 6 (November 2009): 427-434.  Link to Item
    • Balajee, SA, Kano, R, Baddley, JW, Moser, SA, Marr, KA, Alexander, BD, Andes, D, Kontoyiannis, DP, Perrone, G, Peterson, S, Brandt, ME, Pappas, PG, and Chiller, T. "Molecular identification of Aspergillus species collected for the Transplant-Associated Infection Surveillance Network." Journal of Clinical Microbiology 47, no. 10 (October 2009): 3138-3141.  Full Text
    • Pfaller, MA, Diekema, DJ, Ghannoum, MA, Rex, JH, Alexander, BD, Andes, D, Brown, SD, Chaturvedi, V, Espinel-Ingroff, A, Fowler, CL, Johnson, EM, Knapp, CC, Motyl, MR, Ostrosky-Zeichner, L, Sheehan, DJ, Walsh, TJ, and Clinical and Laboratory Standards Institute Antifungal Testing Subcommittee, . "Wild-type MIC distribution and epidemiological cutoff values for Aspergillus fumigatus and three triazoles as determined by the Clinical and Laboratory Standards Institute broth microdilution methods." Journal of Clinical Microbiology 47, no. 10 (October 2009): 3142-3146.  Full Text
    • Shi, S, Ashley, ES, Alexander, BD, and Hickey, AJ. "Initial characterization of micafungin pulmonary delivery via two different nebulizers and multivariate data analysis of aerosol mass distribution profiles." AAPS PharmSciTech 10, no. 1 (2009): 129-137. (Academic Article)  Full Text
    • Ostrosky-Zeichner, L, Rex, JH, Pfaller, MA, Diekema, DJ, Alexander, BD, Andes, D, Brown, SD, Chaturvedi, V, Ghannoum, MA, Knapp, CC, Sheehan, DJ, and Walsh, TJ. "Rationale for reading fluconazole MICs at 24 hours rather than 48 hours when testing Candida spp. by the CLSI M27-A2 standard method." Antimicrobial Agents and Chemotherapy 52, no. 11 (November 2008): 4175-4177.  Full Text
    • Alexander, BD, Perfect, JR, Daly, JS, Restrepo, A, Tobón, AM, Patino, H, Hardalo, CJ, and Graybill, JR. "Posaconazole as salvage therapy in patients with invasive fungal infections after solid organ transplant." Transplantation 86, no. 6 (September 27, 2008): 791-796.  Full Text  Link to Item
    • Singh, N, Lortholary, O, Dromer, F, Alexander, BD, Gupta, KL, John, GT, del Busto, R, Klintmalm, GB, Somani, J, Lyon, GM, Pursell, K, Stosor, V, Munoz, P, Limaye, AP, Kalil, AC, Pruett, TL, Garcia-Diaz, J, Humar, A, Houston, S, House, AA, Wray, D, Orloff, S, Dowdy, LA, Fisher, RA, Heitman, J, Wagener, MM, Husain, S, and Cryptococcal Collaborative Transplant Study Group, . "Central nervous system cryptococcosis in solid organ transplant recipients: clinical relevance of abnormal neuroimaging findings." Transplantation 86, no. 5 (September 2008): 647-651.  Full Text
    • Pfaller, MA, Diekema, DJ, Ostrosky-Zeichner, L, Rex, JH, Alexander, BD, Andes, D, Brown, SD, Chaturvedi, V, Ghannoum, MA, Knapp, CC, Sheehan, DJ, and Walsh, TJ. "Correlation of MIC with outcome for Candida species tested against caspofungin, anidulafungin, and micafungin: analysis and proposal for interpretive MIC breakpoints." Journal of Clinical Microbiology 46, no. 8 (August 2008): 2620-2629.  Full Text
    • Alexander, BD, Petzold, EW, Reller, LB, Palmer, SM, Davis, RD, Woods, CW, and Lipuma, JJ. "Survival after lung transplantation of cystic fibrosis patients infected with Burkholderia cepacia complex." Am J Transplant 8, no. 5 (May 2008): 1025-1030.  Full Text  Link to Item
    • Kontoyiannis, DP, Lewis, RE, Alexander, BD, Lortholary, O, Dromer, F, Gupta, KL, John, GT, Del Busto, R, Klintmalm, GB, Somani, J, Lyon, GM, Pursell, K, Stosor, V, Munoz, P, Limaye, AP, Kalil, AC, Pruett, TL, Garcia-Diaz, J, Humar, A, Houston, S, House, AA, Wray, D, Orloff, S, Dowdy, LA, Fisher, RA, Heitman, J, Albert, ND, Wagener, MM, and Singh, N. "Calcineurin inhibitor agents interact synergistically with antifungal agents in vitro against Cryptococcus neoformans isolates: correlation with outcome in solid organ transplant recipients with cryptococcosis." Antimicrobial Agents and Chemotherapy 52, no. 2 (February 2008): 735-738.  Full Text
    • Shepard, JR, Addison, RM, Alexander, BD, Della-Latta, P, Gherna, M, Haase, G, Hall, G, Johnson, JK, Merz, WG, Peltroche-Llacsahuanga, H, Stender, H, Venezia, RA, Wilson, D, Procop, GW, Wu, F, and Fiandaca, MJ. "Multicenter evaluation of the Candida albicans/Candida glabrata peptide nucleic acid fluorescent in situ hybridization method for simultaneous dual-color identification of C. albicans and C. glabrata directly from blood culture bottles." Journal of Clinical Microbiology 46, no. 1 (January 2008): 50-55.  Full Text
    • Singh, N, Alexander, BD, Lortholary, O, Dromer, F, Gupta, KL, John, GT, del Busto, R, Klintmalm, GB, Somani, J, Lyon, GM, Pursell, K, Stosor, V, Muñoz, P, Limaye, AP, Kalil, AC, Pruett, TL, Garcia-Diaz, J, Humar, A, Houston, S, House, AA, Wray, D, Orloff, S, Dowdy, LA, Fisher, RA, Heitman, J, Wagener, MM, and Husain, S. "Pulmonary cryptococcosis in solid organ transplant recipients: clinical relevance of serum cryptococcal antigen." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America 46, no. 2 (January 2008): e12-e18.  Full Text
    • Alexander, BD, and Hanson, K. "Infections in the Transplant Recipient." (December 13, 2007): 439-459. (Chapter)  Full Text
    • Cohen-Wolkowiez, M, Benjamin, DK, Fowler, VG, Wade, KC, Alexander, BD, Worley, G, Goldstein, RF, and Smith, PB. "Mortality and neurodevelopmental outcome after Staphylococcus aureus bacteremia in infants." The Pediatric Infectious Disease Journal 26, no. 12 (December 2007): 1159-1161.  Full Text
    • Gellad, ZF, Alexander, BD, Liu, JK, Griffith, BC, Meyer, AM, Johnson, JL, and Muir, AJ. "Severity of Clostridium difficile-associated diarrhea in solid organ transplant patients." Transpl Infect Dis 9, no. 4 (December 2007): 276-280.  Full Text  Link to Item
    • Bressler, AM, Kaye, KS, LiPuma, JJ, Alexander, BD, Moore, CM, Reller, LB, and Woods, CW. "Risk factors for Burkholderia cepacia complex bacteremia among intensive care unit patients without cystic fibrosis: a case-control study." Infect Control Hosp Epidemiol 28, no. 8 (August 2007): 951-958.  Full Text  Link to Item
    • Smith, PB, Benjamin, DK, Alexander, BD, Johnson, MD, Finkelman, MA, and Steinbach, WJ. "Quantification of 1,3-beta-D-glucan levels in children: preliminary data for diagnostic use of the beta-glucan assay in a pediatric setting." Clinical and Vaccine Immunology : Cvi 14, no. 7 (July 2007): 924-925.  Full Text
    • Steinbach, WJ, Addison, RM, McLaughlin, L, Gerrald, Q, Martin, PL, Driscoll, T, Bentsen, C, Perfect, JR, and Alexander, BD. "Prospective Aspergillus galactomannan antigen testing in pediatric hematopoietic stem cell transplant recipients." Pediatr Infect Dis J 26, no. 7 (July 2007): 558-564.  Full Text  Link to Item
    • Hanson, KE, Reller, LB, Kurtzberg, J, Horwitz, M, Long, G, and Alexander, BD. "Comparison of the Digene Hybrid Capture System Cytomegalovirus (CMV) DNA (version 2.0), Roche CMV UL54 analyte-specific reagent, and QIAGEN RealArt CMV LightCycler PCR reagent tests using AcroMetrix OptiQuant CMV DNA quantification panels and specimens from allogeneic-stem-cell transplant recipients." Journal of Clinical Microbiology 45, no. 6 (June 2007): 1972-1973.  Full Text
    • Ostrosky-Zeichner, L, Sable, C, Sobel, J, Alexander, BD, Donowitz, G, Kan, V, Kauffman, CA, Kett, D, Larsen, RA, Morrison, V, Nucci, M, Pappas, PG, Bradley, ME, Major, S, Zimmer, L, Wallace, D, Dismukes, WE, and Rex, JH. "Multicenter retrospective development and validation of a clinical prediction rule for nosocomial invasive candidiasis in the intensive care setting." Eur J Clin Microbiol Infect Dis 26, no. 4 (April 2007): 271-276.  Full Text  Link to Item
    • Alexander, BD, Byrne, TC, Smith, KL, Hanson, KE, Anstrom, KJ, Perfect, JR, and Reller, LB. "Comparative evaluation of Etest and sensititre yeastone panels against the Clinical and Laboratory Standards Institute M27-A2 reference broth microdilution method for testing Candida susceptibility to seven antifungal agents." Journal of Clinical Microbiology 45, no. 3 (March 2007): 698-706.  Full Text
    • Hanson, KE, Alexander, BD, Woods, C, Petti, C, and Reller, LB. "Validation of laboratory screening criteria for herpes simplex virus testing of cerebrospinal fluid." Journal of Clinical Microbiology 45, no. 3 (March 2007): 721-724.  Full Text
    • Singh, N, Alexander, BD, Lortholary, O, Dromer, F, Gupta, KL, John, GT, del Busto, R, Klintmalm, GB, Somani, J, Lyon, GM, Pursell, K, Stosor, V, Munoz, P, Limaye, AP, Kalil, AC, Pruett, TL, Garcia-Diaz, J, Humar, A, Houston, S, House, AA, Wray, D, Orloff, S, Dowdy, LA, Fisher, RA, Heitman, J, Wagener, MM, Husain, S, and Cryptococcal Collaborative Transplant Study Group, . "Cryptococcus neoformans in organ transplant recipients: impact of calcineurin-inhibitor agents on mortality." The Journal of Infectious Diseases 195, no. 5 (March 2007): 756-764.  Full Text
    • Cohen-Wolkowiez, M, Smith, PB, Mangum, B, Steinbach, WJ, Alexander, BD, Cotten, CM, Clark, RH, Walsh, TJ, and Benjamin, DK. "Neonatal Candida meningitis: significance of cerebrospinal fluid parameters and blood cultures." Journal of Perinatology : Official Journal of the California Perinatal Association 27, no. 2 (February 2007): 97-100.  Full Text
    • Weinberg, JB, Alexander, BD, Majure, JM, Williams, LW, Kim, JY, Vandamme, P, and LiPuma, JJ. "Burkholderia glumae infection in an infant with chronic granulomatous disease." Journal of Clinical Microbiology 45, no. 2 (February 2007): 662-665.  Full Text
    • Zaas, AK, Dodds Ashley, ES, Alexander, BD, Johnson, MD, and Perfect, JR. "Caspofungin for invasive candidiasis at a tertiary care medical center." The American Journal of Medicine 119, no. 11 (November 2006): 993.e1-993.e6.  Full Text
    • Anaissie, EJ, Segal, BH, Graybill, JR, Arndt, C, Perfect, JR, Kleinberg, M, Pappas, P, Benjamin, D, Rubin, R, Aberg, JA, Adderson, EE, Adler-Shohet, FC, Akan, H, Akova, M, Almyroudis, NG, Alexander, BD, Andes, D, Arrieta, A, Baddley, JW, Barron, MA, Belzberg, H, Boucher, HW, Boyce, TG, Casadevall, A, Chandrasekar, PH, Cleary, JD, Cordonnier, C, Cornely, OA, Cuenca-Estrella, M, Daly, JS, Daoura, N, Denning, DW, dePauw, B, de Repentigny, L, Dignani, MC, Dismukes, WE, Donnelly, JP, Donowitz, GR, Dupont, B, Drusano, G, Ellis, M, Espinel-Ingroff, A, Fishman, JA, Fleming, R, Forrest, G, Ghannoum, M, Goldman, M, Grazziutti, M, Greene, JN, Greenberg, RN, Gubbins, PO, Hadley, S, Herbrecht, R, Hiemenz, JW, Hope, W, Hospenthal, DR, Husain, S, Ito, JI, Jacobson, RM, Johnson, M, Keating, MR, Kett, DH, Knapp, K, Kontoyiannis, DP, Krcmery, VC, Larsen, R, Laverdiere, M, Ljungman, P, Lortholary, O, Maertens, J, Marriott, D, Mattiuzzi, G, McGinnis, MR, Morris, M, Nucci, M, Odds, FC, Pankey, GA, Patterson, T, Pfaller, M, Razonable, RR, Reboli, AC, Rinaldi, MG, Roberts, GD, Rodriguez Tudela, JL, Rotstein, C, Ruhnke, M, Schuster, M, Shoham, S, Sia, IG, Siebel, N, Silviera, F, Singh, N, Sobel, J, Solomkin, JS, Sorrell, TC, Steinbach, WJ, Temesgen, Z, Tortorano, A, Vartivarian, S, VerWeij, P, Viscoli, C, Viviani, MA, Walker, RC, Wheat, JL, Wiley, J, Williamson, P, Wingard, JR, Yu, VL, and Zaoutis, T. "Clinical research in the lay press: irresponsible journalism raises a huge dose of doubt." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America 43, no. 8 (October 2006): 1031-1039.  Full Text
    • Alexander, BD, Ashley, ED, Reller, LB, and Reed, SD. "Cost savings with implementation of PNA FISH testing for identification of Candida albicans in blood cultures." Diagnostic Microbiology and Infectious Disease 54, no. 4 (April 2006): 277-282.  Full Text
    • Alexander, BD, Dodds Ashley, ES, Addison, RM, Alspaugh, JA, Chao, NJ, and Perfect, JR. "Non-comparative evaluation of the safety of aerosolized amphotericin B lipid complex in patients undergoing allogeneic hematopoietic stem cell transplantation." Transpl Infect Dis 8, no. 1 (March 2006): 13-20.  Full Text  Link to Item
    • Alexander, BD, and Pfaller, MA. "Contemporary tools for the diagnosis and management of invasive mycoses." Clinical Infectious Diseases 43, no. SUPPL. 1 (2006): S15-S27.  Full Text
    • Hanson, K, and Alexander, B. "Strategies for the prevention of infection after solid organ transplantation." Expert Review of Anti-Infective Therapy 4, no. 5 (2006): 837-852.  Full Text
    • Costa, SF, and Alexander, BD. "Non-Aspergillus fungal pneumonia in transplant recipients." Clin Chest Med 26, no. 4 (December 2005): 675-vii. (Review)  Full Text  Link to Item
    • Razonable, RR, Brown, RA, Humar, A, Covington, E, Alecock, E, Paya, CV, and PV16000 Study Group, . "A longitudinal molecular surveillance study of human polyomavirus viremia in heart, kidney, liver, and pancreas transplant patients." The Journal of Infectious Diseases 192, no. 8 (October 2005): 1349-1354.  Full Text
    • Singh, N, Lortholary, O, Alexander, BD, Gupta, KL, John, GT, Pursell, K, Munoz, P, Klintmalm, GB, Stosor, V, delBusto, R, Limaye, AP, Somani, J, Lyon, M, Houston, S, House, AA, Pruett, TL, Orloff, S, Humar, A, Dowdy, L, Garcia-Diaz, J, Fisher, RA, Husain, S, and Cryptococcal Collaborative Transplant Study Group, . "Allograft loss in renal transplant recipients with cryptococcus neoformans associated immune reconstitution syndrome." Transplantation 80, no. 8 (October 2005): 1131-1133.  Full Text
    • Singh, N, Lortholary, O, Alexander, BD, Gupta, KL, John, GT, Pursell, KJ, Muñoz, P, Klintmalm, GB, Stosor, V, Del Busto, R, Limaye, AP, Somani, J, Lyon, M, Houston, S, House, AA, Pruett, TL, Orloff, S, Humar, A, Dowdy, LA, Garcia-Diaz, J, Kalil, AC, Fisher, RA, Heitman, J, and Husain, S. "Antifungal management practices and evolution of infection in organ transplant recipients with cryptococcus neoformans infection." Transplantation 80, no. 8 (October 2005): 1033-1039.  Full Text
    • Alexander, BD, Schell, WA, Miller, JL, Long, GD, and Perfect, JR. "Candida glabrata fungemia in transplant patients receiving voriconazole after fluconazole." Transplantation 80, no. 6 (September 27, 2005): 868-871.  Link to Item
    • Ostrosky-Zeichner, L, Alexander, BD, Kett, DH, Vazquez, J, Pappas, PG, Saeki, F, Ketchum, PA, Wingard, J, Schiff, R, Tamura, H, Finkelman, MA, and Rex, JH. "Multicenter clinical evaluation of the (1-->3) beta-D-glucan assay as an aid to diagnosis of fungal infections in humans." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America 41, no. 5 (September 2005): 654-659.  Full Text
    • Upton, A, Gugel, A, Leisenring, W, Limaye, A, Alexander, B, Hayden, R, and Marr, KA. "Reproducibility of low galactomannan enzyme immunoassay index values tested in multiple laboratories." Journal of Clinical Microbiology 43, no. 9 (September 2005): 4796-4800.  Full Text
    • Zaas, AK, and Alexander, BD. "Echinocandins: role in antifungal therapy, 2005." Expert Opin Pharmacother 6, no. 10 (August 2005): 1657-1668. (Review)  Full Text  Link to Item
    • Dodds Ashley, ES, and Alexander, BD. "Posaconazole." Drugs of today (Barcelona, Spain : 1998) 41, no. 6 (June 2005): 393-400. (Review)  Full Text
    • Singh, N, Lortholary, O, Alexander, BD, Gupta, KL, John, GT, Pursell, K, Munoz, P, Klintmalm, GB, Stosor, V, del Busto, R, Limaye, AP, Somani, J, Lyon, M, Houston, S, House, AA, Pruett, TL, Orloff, S, Humar, A, Dowdy, L, Garcia-Diaz, J, Kalil, AC, Fisher, RA, Husain, S, and Cryptococcal Collaborative Transplant Study Group, . "An immune reconstitution syndrome-like illness associated with Cryptococcus neoformans infection in organ transplant recipients." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America 40, no. 12 (June 2005): 1756-1761.  Full Text
    • Wilson, DA, Joyce, MJ, Hall, LS, Reller, LB, Roberts, GD, Hall, GS, Alexander, BD, and Procop, GW. "Multicenter evaluation of a Candida albicans peptide nucleic acid fluorescent in situ hybridization probe for characterization of yeast isolates from blood cultures." Journal of Clinical Microbiology 43, no. 6 (June 2005): 2909-2912.  Full Text
    • Wiltshire, H, Paya, CV, Pescovitz, MD, Humar, A, Dominguez, E, Washburn, K, Blumberg, E, Alexander, B, Freeman, R, Heaton, N, Zuideveld, KP, and Valganciclovir Solid Organ Transplant Study Group, . "Pharmacodynamics of oral ganciclovir and valganciclovir in solid organ transplant recipients." Transplantation 79, no. 11 (June 2005): 1477-1483.  Full Text
    • Alexander, BD, and Wingard, JR. "Study of renal safety in amphotericin B lipid complex-treated patients." Clin Infect Dis 40 Suppl 6 (May 1, 2005): S414-S421.  Full Text  Link to Item
    • Alexander, BD, and Dines, TJ. "Chemical interactions in the surface-enhanced resonance Raman scattering of ruthenium polypyridyl complexes." J Phys Chem B 109, no. 8 (March 3, 2005): 3310-3318.  Full Text  Link to Item
    • Alexander, BD. "Cryptococcosis after solid organ transplantation." Transpl Infect Dis 7, no. 1 (March 2005): 1-3.  Full Text  Link to Item
    • Blankenship, JR, Singh, N, Alexander, BD, and Heitman, J. "Cryptococcus neoformans isolates from transplant recipients are not selected for resistance to calcineurin inhibitors by current immunosuppressive regimens." Journal of Clinical Microbiology 43, no. 1 (January 2005): 464-467.  Full Text
    • Husain, S, Muñoz, P, Forrest, G, Alexander, BD, Somani, J, Brennan, K, Wagener, MM, and Singh, N. "Infections due to Scedosporium apiospermum and Scedosporium prolificans in transplant recipients: clinical characteristics and impact of antifungal agent therapy on outcome." Clinical Infectious Diseases: an Official Publication of the Infectious Diseases Society of America 40, no. 1 (January 2005): 89-99.  Full Text
    • Wiltshire, H, Hirankarn, S, Farrell, C, Paya, C, Pescovitz, MD, Humar, A, Dominguez, E, Washburn, K, Blumberg, E, Alexander, B, Freeman, R, Heaton, N, and Valganciclovir Solid Organ Transplant Study Group, . "Pharmacokinetic profile of ganciclovir after its oral administration and from its prodrug, valganciclovir, in solid organ transplant recipients." Clinical Pharmacokinetics 44, no. 5 (January 2005): 495-507.  Full Text
    • Zaas, AK, and Alexander, BD. "Galactomannan and advances in fungal diagnostics." Current Opinion in Organ Transplantation 10, no. 4 (2005): 307-311.  Full Text
    • Freeman, RB, Paya, C, Pescovitz, MD, Humar, A, Dominguez, E, Washburn, K, Blumberg, E, Alexander, B, Heaton, N, and Valganciclovir Solid Organ Transplant Study Group, . "Risk factors for cytomegalovirus viremia and disease developing after prophylaxis in high-risk solid-organ transplant recipients." Transplantation 78, no. 12 (December 2004): 1765-1773.  Full Text
    • Zaas, AK, and Alexander, BD. "New developments in the diagnosis and treatment of infections in lung transplant recipients." Respir Care Clin N Am 10, no. 4 (December 2004): 531-547. (Review)  Full Text  Link to Item
    • Boivin, G, Goyette, N, Gilbert, C, Roberts, N, Macey, K, Paya, C, Pescovitz, MD, Humar, A, Dominguez, E, Washburn, K, Blumberg, E, Alexander, B, Freeman, R, Heaton, N, and Covington, E. "Absence of cytomegalovirus-resistance mutations after valganciclovir prophylaxis, in a prospective multicenter study of solid-organ transplant recipients." The Journal of Infectious Diseases 189, no. 9 (May 2004): 1615-1618.  Full Text
    • Woods, CW, Bressler, AM, LiPuma, JJ, Alexander, BD, Clements, DA, Weber, DJ, Moore, CM, Reller, LB, and Kaye, KS. "Virulence associated with outbreak-related strains of Burkholderia cepacia complex among a cohort of patients with bacteremia." Clin Infect Dis 38, no. 9 (May 1, 2004): 1243-1250.  Full Text  Link to Item
    • Humar, A, Paya, C, Pescovitz, MD, Dominguez, E, Washburn, K, Blumberg, E, Alexander, B, Freeman, R, Heaton, N, and Mueller, B. "Clinical utility of cytomegalovirus viral load testing for predicting CMV disease in D+/R- solid organ transplant recipients." American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons 4, no. 4 (April 2004): 644-649.  Full Text
    • Paya, C, Humar, A, Dominguez, E, Washburn, K, Blumberg, E, Alexander, B, Freeman, R, Heaton, N, Pescovitz, MD, and Valganciclovir Solid Organ Transplant Study Group, . "Efficacy and safety of valganciclovir vs. oral ganciclovir for prevention of cytomegalovirus disease in solid organ transplant recipients." American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons 4, no. 4 (April 2004): 611-620.  Full Text
    • Lodge, BA, Ashley, ED, Steele, MP, and Perfect, JR. "Aspergillus fumigatus empyema, arthritis, and calcaneal osteomyelitis in a lung transplant patient successfully treated with posaconazole." Journal of Clinical Microbiology 42, no. 3 (March 2004): 1376-1378.  Full Text
    • Alexander, BD, and Dines, TJ. "Ab initio calculations and normal coordinate analysis of ruthenium tris-alpha-diimine complexes." Inorg Chem 43, no. 1 (January 12, 2004): 342-350.  Full Text  Link to Item
    • Friedman, ND, Peterson, NB, Sumner, WT, and Alexander, BD. "Spontaneous dermal abscesses and ulcers as a result of Serratia marcescens." J Am Acad Dermatol 49, no. 2 Suppl Case Reports (August 2003): S193-S194.  Full Text  Link to Item
    • Stryjewski, ME, LiPuma, JJ, Messier, RH, Reller, LB, and Alexander, BD. "Sepsis, multiple organ failure, and death due to Pandoraea pnomenusa infection after lung transplantation." Journal of Clinical Microbiology 41, no. 5 (May 2003): 2255-2257.  Full Text
    • Friedman, ND, Peterson, NB, Sumner, WT, and Alexander, BD. "Spontaneous dermal abscesses and ulcers as a result of serratia marcescens." Journal of the American Academy of Dermatology 49, no. 2 B (2003): S193-S194.
    • Singh, N, Avery, RK, Munoz, P, Pruett, TL, Alexander, B, Jacobs, R, Tollemar, JG, Dominguez, EA, Yu, CM, Paterson, DL, Husain, S, Kusne, S, and Linden, P. "Trends in risk profiles for and mortality associated with invasive aspergillosis among liver transplant recipients." Clinical Infectious Diseases 36, no. 1 (2003): 46-52.  Full Text
    • Alexander, BD. "Prophylaxis of invasive mycoses in solid organ transplantation." Current Opinion in Infectious Diseases 15, no. 6 (December 2002): 583-589. (Review)  Full Text
    • Alexander, BD. "Diagnosis of fungal infection: new technologies for the mycology laboratory." Transpl Infect Dis 4 Suppl 3 (2002): 32-37. (Review)  Link to Item
    • Alexander, BD, Stout, JE, Reller, LB, and Hamilton, CD. "Hospital management of tuberculosis in a region with a low incidence of tuberculosis and a high prevalence of nontuberculous mycobacteria." Infect Control Hosp Epidemiol 22, no. 11 (November 2001): 715-717.  Full Text  Link to Item
    • Alexander, BD, and Tapson, VF. "Infectious complications of lung transplantation." Transplant Infectious Disease : an Official Journal of the Transplantation Society 3, no. 3 (September 2001): 128-137. (Review)  Full Text
    • Smith, SR, Butterly, DW, Alexander, BD, and Greenberg, A. "Viral infections after renal transplantation." Am J Kidney Dis 37, no. 4 (April 2001): 659-676. (Review)  Link to Item
    • Stout, JE, McDonald, JR, Engemann, JJ, Alexander, BD, and Hamilton, CD. "Conditions associated with pulmonary non-tuberculous mycobacteria (NTM) in a tertiary care hospital in the Southeastern US." CLINICAL INFECTIOUS DISEASES 31, no. 1 (July 2000): 311-311.  Link to Item
    • Palmer, SM, Alexander, BD, Sanders, LL, Edwards, LJ, Reller, LB, Davis, RD, and Tapson, VF. "Significance of blood stream infection after lung transplantation: analysis in 176 consecutive patients." Transplantation 69, no. 11 (June 15, 2000): 2360-2366.  Link to Item
    • Dictar, MO, Maiolo, E, Alexander, B, Jacob, N, and Verón, MT. "Mycoses in the transplanted patient." Medical Mycology 38, no. SUPPL. 1 (2000): 251-258.
    • Alexander, BD, Palmer, SM, Tapson, VF, Davis, RD, and Reller, LB. "Bacteremia and fungemia in lung transplant recipients at Duke University Medical Center." AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 159, no. 3 (March 1999): A738-A738.  Link to Item
    • Alexander, BD, Stout, JE, Reller, LB, and Hamilton, CD. "Hospital management of patients suspected of pulmonary TB in a high incidence area for MOTT." AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 159, no. 3 (March 1999): A304-A304.  Link to Item
    • Alexander, BD, and Perfect, JR. "Antifungal resistance trends towards the year 2000. Implications for therapy and new approaches." Drugs 54, no. 5 (November 1997): 657-678. (Review)  Link to Item
    • Husain, S, Alexander, BD, Munoz, P, Avery, RK, Houston, S, Pruett, T, Jacobs, R, Dominguez, EA, Tollemar, JG, Baumgarten, K, Yu, CM, Wagener, MM, Linden, P, Kusne, S, and Singh, N. "Opportunistic mycelial fungal infections in organ transplant recipients: emerging importance of non-Aspergillus mycelial fungi." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America 37, no. 2 (July 9, 2003): 221-229.  Full Text

  • Book Sections

    • Perfect, JR, Alexander, BD, and Schell, WA. "Phaeohyphomycoses (brown-black moulds)." In Essentials of Clinical Mycology: Second Edition, 305-317. January 1, 2011.  Full Text

  • Conference Papers

    • Lamoth, F, and Alexander, BD. "Antifungal Susceptibility Testing to Predict Appropriate Initial Antifungal Therapy and Outcome in non-Aspergillus Invasive Mold Infections." October 2015.  Link to Item
    • Sun, HY, Alexander, BD, Singh, N, and Gp, CCT. "Early-Onset Cryptococcosis in Solid Organ Transplant (SOT) Recipients." April 2010.  Link to Item
    • Pal, JD, Alexander, BD, Lodge, AJ, Blue, L, and Milano, CA. "Successful Management of Pump Pocket Infections in Patients with Implanted Left Ventricular Assist Devices." February 2009.  Full Text  Link to Item
    • Singh, N, Lortholary, O, Alexander, BD, and Husain, S. "CNS cryptococcal lesions in solid organ transplant recipients with cryptococcosis." May 2008.  Link to Item
    • Gellad, ZF, Alexander, BD, Liu, JK, Griffith, BC, Meyer, AM, Johnson, JL, and Muir, AJ. "Severity of Clostridium difficile associated diarrhea in solid-organ transplant patients." September 2006.  Link to Item
    • Ashley, ESD, Alexander, BD, Perfect, JR, and Drew, RH. "Cost-avoidance associated with infectious diseases clinical research." March 2003.  Link to Item

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