Alexander Tan Limkakeng Jr.

Alexander Tan Limkakeng Jr.
Associate Professor of Surgery

My personal research interest is finding new ways to diagnose acute coronary syndrome . In particular, I am interested in novel biomarkers and precision medicine approaches to this problem. As Vice Chief of Research for the Duke Division of Emergency Medicine, I work with researchers from many fields spanning global health, innovation, clinical trials, basic discovery and translational research. The common element is time-sensitive health conditions.

Current Research Interests

Acute Coronary Syndrome, Biomarkers, Myocardial Ischemia, Precision Medicine, Septic Shock, Clinical Trials

Current Appointments & Affiliations

Associate Professor of Surgery, Surgery, Emergency Medicine, Surgery 2013

Contact Information

2301 Erwin Road, Box 3096, Durham, NC 27710
(919) 681-0196
Duke Emergency Medicine Research

Background
Education, Training, & Certifications
- M.H.S., Duke University 2012
- M.D., University of Pennsylvania 2001
Duke Appointment History
- Assistant Professor of Surgery, Surgery, Emergency Medicine, Surgery 2007 - 2013
- Instructor, Temporary in the Department of Surgery, Surgery, Emergency Medicine, Surgery 2006 - 2007
Leadership & Clinical Positions at Duke
- Vice Chief of Research
  Director, Acute Care Research Team
Academic Positions Outside Duke
- Assistant Director, American College of Emergency Physicians Emergency Medicine Basic Research Skills (EMBRS) Course. 2018
- Co-Director, American College of Emergency Physicians Research Forum. 2016 - 2018
Recognition
In the News
- JUL 11, 2017 Bass Connections
  
  These Kits Will Save Lives, But There Is Much More Work Ahead to Stem the Opiate Epidemic
Awards & Honors
Expertise
Subject Headings
Research
Selected Grants
- Portable motion-stabilized optical coherence tomography for eye care in acute care settings awarded by National Institutes of Health 2018 - 2021
- Comparison of Dyspnea Measurement Instruments in Acute Heart Failure awarded by Heart Failure Society of America 2017 - 2019
- CCC for NHLBI Prevention and early Treatment of Acute Lung Injury PETAL Network - CLOVERS awarded by Vanderbilt University Medical Center 2017 - 2019
- CCC for NHLBI Prevention and early Treatment of Acute Lung Injury PETAL Network - VIOLET awarded by Vanderbilt University Medical Center 2017 - 2019
- Energize awarded by AstraZeneca AB 2018 - 2019
- Assessment of Clinical Performance of Troponin Assays awarded by Siemens AG 2014 - 2019
- Biomarkers for Acute Stroke Etilogy (BASE) awarded by Ischemia Care LLC 2016 - 2018
- SC2i awarded by Henry M. Jackson Foundation 2014 - 2018
- Abbott Stress-Delta Biomarkers for ACS Risk Stratification awarded by Abbott Laboratories 2014 - 2018
- MultiCenter trial of Rivaroxban for Early Discharge of Pulmonary Embolism from the ER awarded by Janssen Scientific Affairs, LLC. 2016 - 2017
- ACS Collection Study for Serum Claim awarded by Roche Diagnostics 2014 - 2017
- ARCHITECT STAT High Sensitive Troponin-I Assay Clinical Evaluation for Specimen Storage in Varying Specimen Tube Types awarded by Abbott Laboratories 2013 - 2015
- D-Dimer DVT/PE Exclusionary Sample Collection Project awarded by Siemens AG 2013 - 2015
Publications & Artistic Works
Selected Publications
- Book Sections
  - Limkakeng AT, Kemnitz MG. Globe rupture. In: Rosen and Barkin's 5-Minute Emergency Medicine Consult: Fifth Edition. 2014 Jul 7.
- Conference Papers
  - Broder JS, Jaffa E, Irons T, Peethumnongsin E, Theophanous R, Limkakeng AT, Vissoci JR, Morgan MR, Herickhoff CD, Dahl JJ. 3D Volume Ultrasound of the Right Lower Quadrant for Diagnosis of Appendicitis. Research Forum of the American-College-of-Emergency-Physicians (ACEP). 2018 Oct 1 - 2018 Oct 3. San Diego, CA.: MOSBY-ELSEVIER; 2018 Oct 1:S85-S85. Full Text Link to Item
  - Goldberg DF, Borawski JB, Limkakeng AT, Kaji AH, Ruderman BT, Fantegrossi AE, Griffin M. Utilization of Bougie Adjunct Devices in the Emergency Department: A National Emergency Airway Registry Study. Research Forum of the American-College-of-Emergency-Physicians (ACEP). 2018 Oct 1 - 2018 Oct 3. San Diego, CA.: MOSBY-ELSEVIER; 2018 Oct 1:S57-S57. Full Text Link to Item
  - Greene SJ, Mentz RJ, Limkakeng AT, Irons T, Truong T, Green CL, Nowak C, Griffin S, Leahy J, Pang PS. Comparison of Dyspnea Measurement Instruments in Acute Heart Failure: Results From the DYSPNEA-AHF Study. Research Forum of the American-College-of-Emergency-Physicians (ACEP). 2018 Oct 1 - 2018 Oct 3. San Diego, CA.: MOSBY-ELSEVIER; 2018 Oct 1:S29-S29. Full Text Link to Item
  - Limkakeng AT, Griffin M, Leahy C, Hatch A, Rowlette L, Voora D, Nixon A. Isolating Micro-Ribonucleic Acids from Peripheral Plasma to Identify Myocardial Ischemia During Stress Testing in Emergency Department Patients. Research Forum of the American-College-of-Emergency-Physicians (ACEP). 2018 Oct 1 - 2018 Oct 3. San Diego, CA.: MOSBY-ELSEVIER; 2018 Oct 1:S16-S16. Full Text Link to Item
  - Ruderman BT, Mali M, Kaji A, Borawski JB, Limkakeng AT, Kilgo R, Goldberg DF, Fantegrossi AE, Brown CA. A Comparison of Direct Versus Video Laryngoscopy for Difficult Airway Patients in the Emergency Department: A National Emergency Airway Registry Study. Research Forum of the American-College-of-Emergency-Physicians (ACEP). 2018 Oct 1 - 2018 Oct 3. San Diego, CA.: MOSBY-ELSEVIER; 2018 Oct 1:S42-S43. Full Text Link to Item
  - Fitzgerald R, deFilippi C, Hollander J, Peacock WF, Limkakeng AT, Breitenbeck N, Rivers J, Kareen B. OVERALL AND SEX-SPECIFIC REFERENCE RANGES FOR HIGH-SENSITIVITY TROPONIN T GEN 5 STAT IN THE UNITED STATES. 2018 Mar:A233-A233. Full Text
  - Johnston BE, Quigley CA, Griffin SM, Limkakeng AT, Darrabie MD, Cheeseman JA, Kirk AD, Elster EA. 313 Evaluation of Phenylalanine and Tyrosine Concentrations in Traumatically Injured Patients. 2017 Oct:S123-S123. Full Text
  - Limkakeng AT, Carr C, Mehrotra A, Smith L, Pajewski N, Burke GL, Wells BJ, Mahler S. 1 Chest Pain Care Patterns Across the Carolinas: Determining the Readiness for Widespread HEART Pathway Dissemination. 2017 Oct:S1-S1. Full Text
  - Ziegler CE, Painter DM, Borawski JB, Kim RJ, Kim HW, Limkakeng AT. 105 Unexpected Cardiac Magnetic Resonance Imaging Findings in Patients Presenting to the Emergency Department for Potential Acute Coronary Syndrome. 2017 Oct:S42-S42. Full Text
  - Darrabie MD, Lee J, Cheeseman J, Limkakeng AT, Vaslef SN, Sullenger BA, Kirk AD. Toll-Like Receptor Signaling as a Prognostic Tool in Trauma Patients. 2016 Oct:S159-S160. Full Text
  - Freeman D, Diskina M, Drake W, Jones A, Limkakeng AT. The Protocol Acuity Scoring Tool for Prediction of Emergency Medicine Research Study Workload. Research Forum of the American-College-of-Emergency-Physicians (ACEP). 2013 Oct 14 - 2013 Oct 15. Seattle, WA.: MOSBY-ELSEVIER; 2013 Oct 1:S150-S150. Link to Item
- Journal Articles
  - Darrabie MD, Cheeseman J, Limkakeng AT, Borawski J, Sullenger BA, Elster EA, Kirk AD, Lee J. Toll-like receptor activation as a biomarker in traumatically injured patients.(Accepted) The Journal of Surgical Research. 2018 Nov;231:270-277. PubMed Central PMCID: 30278940. Full Text Open Access Copy
  - Hocker MB, Gerardo CJ, Theiling BJ, Villani J, Donohoe R, Sandesara H, Limkakeng AT. NHAMCS Validation of Emergency Severity Index as an Indicator of Emergency Department Resource Utilization. The Western Journal of Emergency Medicine. 2018 Sep;19(5):855-862. PubMed Central PMCID: 30202499. Full Text
  - Kabrhel C, Van Hylckama Vlieg A, Muzikanski A, Singer A, Fermann GJ, Francis S, Limkakeng A, Chang AM, Giordano N, Parry B. Multicenter Evaluation of the YEARS Criteria in Emergency Department Patients Evaluated for Pulmonary Embolism. Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine. 2018 Sep;25(9):987-994. PubMed Central PMCID: 29603819. Full Text
  - Ziegler CE, Painter DM, Borawski JB, Kim RJ, Kim HW, Limkakeng AT. Unexpected Cardiac MRI Findings in Patients Presenting to the Emergency Department for Possible Acute Coronary Syndrome. Critical Pathways in Cardiology. 2018 Sep;17(3):167-171. PubMed Central PMCID: 30044259. Full Text Open Access Copy
  - Puskarich MA, Callaway C, Silbergleit R, Pines JM, Obermeyer Z, Wright DW, Hsia RY, Shah MN, Monte AA, Limkakeng AT, Meisel ZF, Levy PD. Priorities to Overcome Barriers Impacting Data Science Application in Emergency Care Research. Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine. 2018 Jul 18. PubMed Central PMCID: 30019795. Full Text
  - Parry BA, Chang AM, Schellong SM, House SL, Fermann GJ, Deadmon EK, Giordano NJ, Chang Y, Cohen J, Robak N, Singer AJ, Mulrow M, Reibling ET, Francis S, Griffin SM, Prochaska JH, Davis B, McNelis P, Delgado J, Kümpers P, Werner N, Gentile NT, Zeserson E, Wild PS, Limkakeng AT, Walters EL, LoVecchio F, Theodoro D, Hollander JE, Kabrhel C. International, multicenter evaluation of a new D-dimer assay for the exclusion of venous thromboembolism using standard and age-adjusted cut-offs. Thrombosis Research. 2018 Jun;166:63-70. PubMed Central PMCID: 29656169. Full Text Open Access Copy
  - Beri N, Daniels LB, Jaffe A, Mueller C, Anand I, Peacock WF, Hollander JE, DeFilippi C, Schreiber D, McCord J, Limkakeng AT, Wu AHB, Apple FS, Diercks DB, Nagurney JT, Nowak RM, Cannon CM, Clopton P, Neath S-X, Christenson RH, Hogan C, Vilke G, Maisel A. Copeptin to rule out myocardial infarction in Blacks versus Caucasians. European Heart Journal. Acute Cardiovascular Care. 2018 May:2048872618772500-null. PubMed Central PMCID: 29737180. Full Text
  - Peacock WF, Baumann BM, Bruton D, Davis TE, Handy B, Jones CW, Hollander JE, Limkakeng AT, Mehrotra A, Than M, Ziegler A, Dinkel C. Efficacy of High-Sensitivity Troponin T in Identifying Very-Low-Risk Patients With Possible Acute Coronary Syndrome. JAMA cardiology. 2018 Feb;3(2):104-111. PubMed PMID: 29238804. Full Text
  - de Oliveira LLH, Vissoci JRN, Machado WDL, Rodrigues CG, Limkakeng AT. Are Well-Informed Potential Trial Participants More Likely to Participate?. Journal of Empirical Research on Human Research Ethics : Jerhre. 2017 Dec;12(5):363-371. PubMed Central PMCID: 29073806. Full Text Open Access Copy
  - Gaspari R, Weekes A, Adhikari S, Noble V, Nomura JT, Theodoro D, Woo M, Atkinson P, Blehar D, Brown S, Caffery T, Douglass E, Fraser J, Haines C, Lam S, Lanspa M, Lewis M, Liebmann O, Limkakeng A, Lopez F, Platz E, Mendoza M, Minnigan H, Moore C, Novik J, Rang L, Scruggs W, Raio C. A retrospective study of pulseless electrical activity, bedside ultrasound identifies interventions during resuscitation associated with improved survival to hospital admission. A REASON Study. Resuscitation. 2017 Nov;120:103-107. PubMed PMID: 28916478. Full Text
  - Boyd LR, Borawski J, Lairet J, Limkakeng AT. Critical Care Air Transport Team severe traumatic brain injury short-term outcomes during flight for Operation Iraqi Freedom/Operation Enduring Freedom. Journal of the Royal Army Medical Corps. 2017 Oct;163(5):342-346. PubMed PMID: 28385926. Full Text
  - Borawski JB, Graff LG, Limkakeng AT. Care of the Patient with Chest Pain in the Observation Unit. Emergency medicine clinics of North America. 2017 Aug;35(3):535-547. PubMed PMID: 28711123. (Review) Full Text
  - Early, Goal-Directed Therapy for Septic Shock — A Patient-Level Meta-Analysis. New England Journal of Medicine. 2017 Jun 8;376(23):2223-2234. Full Text
  - Gaspari R, Weekes A, Adhikari S, Noble VE, Nomura JT, Theodoro D, Woo M, Atkinson P, Blehar D, Brown SM, Caffery T, Douglass E, Fraser J, Haines C, Lam S, Lanspa M, Lewis M, Liebmann O, Limkakeng A, Lopez F, Platz E, Mendoza M, Minnigan H, Moore C, Novik J, Rang L, Scruggs W, Raio C. Reply to Letter: Letter to the Editor regarding Gaspari and colleague's "Emergency department point-of-care ultrasound in out-of-hospital and in-ED cardiac arrest". Resuscitation. 2017 May;114:e7-e8. PubMed PMID: 28219757. (Letter) Full Text
  - Beri N, Marston NA, Daniels LB, Nowak RM, Schreiber D, Mueller C, Jaffe A, Diercks DB, Wettersten N, DeFilippi C, Peacock WF, Limkakeng AT, Anand I, McCord J, Hollander JE, Wu AHB, Apple FS, Nagurney JT, Berardi C, Cannon CM, Clopton P, Neath S-X, Christenson RH, Hogan C, Vilke G, Maisel A. Necessity of hospitalization and stress testing in low risk chest pain patients. The American Journal of Emergency Medicine. 2017 Feb;35(2):274-280. PubMed Central PMCID: 27847253. Full Text
  - Mehta R, Nankivil D, Zielinski DJ, Waterman G, Keller B, Limkakeng AT, Kopper R, Izatt JA, Kuo AN. Wireless, Web-Based Interactive Control of Optical Coherence Tomography with Mobile Devices. Translational vision science & technology. 2017 Jan 20;6(1):5-. PubMed PMID: 28138415. Full Text Open Access Copy
  - Limkakeng AT, Drake W, Lokhnygina Y, Meyers HP, Shogilev D, Christenson RH, Newby LK. Myocardial Ischemia on Exercise Stress Echocardiography Testing Is Not Associated with Changes in Troponin T Concentrations. The Journal of Applied Laboratory Medicine. 2017;1:532-543. (Academic Article) Full Text Open Access Copy
  - Gaspari R, Weekes A, Adhikari S, Noble VE, Nomura JT, Theodoro D, Woo M, Atkinson P, Blehar D, Brown SM, Caffery T, Douglass E, Fraser J, Haines C, Lam S, Lanspa M, Lewis M, Liebmann O, Limkakeng A, Lopez F, Platz E, Mendoza M, Minnigan H, Moore C, Novik J, Rang L, Scruggs W, Raio C. Emergency department point-of-care ultrasound in out-of-hospital and in-ED cardiac arrest. Resuscitation. 2016 Dec;109:33-39. PubMed Central PMCID: 27693280. Full Text Open Access Copy
  - Limkakeng AT, Monte AA, Kabrhel C, Puskarich M, Heitsch L, Tsalik EL, Shapiro NI. Systematic Molecular Phenotyping: A Path Toward Precision Emergency Medicine?. Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine. 2016 Oct 3;23(10):1097-1106. PubMed Central PMCID: 27288269. (Review) Full Text Open Access Copy
  - Meyers HP, Jaffa E, Smith SW, Drake W, Limkakeng AT. Evaluation of T-Wave Morphology in Patients With Left Bundle Branch Block and Suspected Acute Coronary Syndrome. The Journal of emergency medicine. 2016 Sep;51(3):229-237. PubMed PMID: 27318856. Full Text
  - Broder JS, Bhat R, Boyd JP, Ogloblin IA, Limkakeng A, Hocker MB, Drake WG, Miller T, Harringa JB, Repplinger MD. Who explicitly requests the ordering of computed tomography for emergency department patients? A multicenter prospective study. Emergency radiology. 2016 Jun;23(3):221-227. PubMed PMID: 26873604. Full Text
  - Tsalik EL, Li Y, Hudson LL, Chu VH, Himmel T, Limkakeng AT, Katz JN, Glickman SW, McClain MT, Welty-Wolf KE, Fowler VG, Ginsburg GS, Woods CW, Reed SD. Potential Cost-effectiveness of Early Identification of Hospital-acquired Infection in Critically Ill Patients. Annals of the American Thoracic Society. 2016 Mar;13(3):401-413. PubMed Central PMCID: 26700878. Full Text Open Access Copy
  - Kellum JA, Chawla LS, Keener C, Singbartl K, Palevsky PM, Pike FL, Yealy DM, Huang DT, Angus DC. The Effects of Alternative Resuscitation Strategies on Acute Kidney Injury in Patients with Septic Shock. American Journal of Respiratory and Critical Care Medicine. 2016 Feb;193(3):281-287. Full Text
  - Marston NA, Shah KS, Mueller C, Neath S-X, Christenson RH, McCord J, Nowak RM, Daniels LB, Hollander JE, Apple F, Nagurney J, Schreiber D, deFilippi C, Diercks D, Limkakeng A, Anand IS, Wu AHB, Jaffe AS, Peacock WF, Maisel AS. Serial sampling of copeptin levels improves diagnosis and risk stratification in patients presenting with chest pain: results from the CHOPIN trial. Emergency medicine journal : EMJ. 2016 Jan;33(1):23-29. PubMed PMID: 26105583. Full Text
  - Hoffman K, Butt CM, Chen A, Limkakeng AT, Stapleton HM. High Exposure to Organophosphate Flame Retardants in Infants: Associations with Baby Products. Environmental science & technology. 2015 Dec;49(24):14554-14559. PubMed PMID: 26551726. Full Text
  - Meyers HP, Limkakeng AT, Jaffa EJ, Patel A, Theiling BJ, Rezaie SR, Stewart T, Zhuang C, Pera VK, Smith SW. Validation of the modified Sgarbossa criteria for acute coronary occlusion in the setting of left bundle branch block: A retrospective case-control study. American heart journal. 2015 Dec;170(6):1255-1264. PubMed PMID: 26678648. Full Text
  - Ranney ML, Limkakeng AT, Carr B, Zink B, Kaji AH, ACEP SAEM Research Committees (approved by ACEP-SAEM Board of Directors) . Improving the Emergency Care Research Investigator Pipeline: SAEM/ACEP Recommendations. Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine. 2015 Jul;22(7):849-851. PubMed Central PMCID: 26112275. Full Text Open Access Copy
  - Shah KS, Marston NA, Mueller C, Neath S-X, Christenson RH, McCord J, Nowak RM, Vilke GM, Daniels LB, Hollander JE, Apple FS, Cannon CM, Nagurney J, Schreiber D, deFilippi C, Hogan CJ, Diercks DB, Limkakeng A, Anand IS, Wu AHB, Clopton P, Jaffe AS, Peacock WF, Maisel AS. Midregional proadrenomedullin predicts mortality and major adverse cardiac events in patients presenting with chest pain: results from the CHOPIN trial. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine. 2015 May;22(5):554-563. PubMed PMID: 25908114. Full Text
  - Limkakeng AT, de Oliveira LLH, Moreira T, Phadtare A, Garcia Rodrigues C, Hocker MB, McKinney R, Voils CI, Pietrobon R. Systematic review and metasummary of attitudes toward research in emergency medical conditions. J Med Ethics. 2014 Jun;40(6):401-408. PubMed PMID: 23665997. (Review) Full Text Open Access Copy Link to Item
  - Hertz JT, Reardon JM, Rodrigues CG, de Andrade L, Limkakeng AT, Bloomfield GS, Lynch CA. Acute myocardial infarction in sub-Saharan Africa: the need for data. Plos One. 2014 Jan;9(5):e96688-null. PubMed Central PMCID: 24816222. (Review) Full Text
  - Chavez J, Srinivasan A, Ely S, Drake W, Freeman D, Borawski J, Chandra A, Limkakeng AT. Thrombolysis in myocardial infarction risk score in an observation unit setting. Crit Pathw Cardiol. 2013 Sep;12(3):137-140. PubMed PMID: 23892944. Full Text Open Access Copy Link to Item
  - Maisel A, Mueller C, Neath S-X, Christenson RH, Morgenthaler NG, McCord J, Nowak RM, Vilke G, Daniels LB, Hollander JE, Apple FS, Cannon C, Nagurney JT, Schreiber D, deFilippi C, Hogan C, Diercks DB, Stein JC, Headden G, Limkakeng AT, Anand I, Wu AHB, Papassotiriou J, Hartmann O, Ebmeyer S, Clopton P, Jaffe AS, Peacock WF. Copeptin helps in the early detection of patients with acute myocardial infarction: primary results of the CHOPIN trial (Copeptin Helps in the early detection Of Patients with acute myocardial INfarction). J Am Coll Cardiol. 2013 Jul 9;62(2):150-160. PubMed PMID: 23643595. Full Text Link to Item
  - Ely S, Chandra A, Mani G, Drake W, Freeman D, Limkakeng AT. Utility of observation units for young emergency department chest pain patients. J Emerg Med. 2013 Feb;44(2):306-312. PubMed PMID: 22975283. Full Text Open Access Copy Link to Item
  - Ely S, Chandra A, Mani G, Drake W, Freeman D, Limkakeng AT. Utility of observation units for young Emergency Department chest pain patients. Journal of Emergency Medicine. 2013;44(2):306-312. Full Text Open Access Copy
  - Limkakeng A, Phadtare A, Shah J, Vaghasia M, Wei DY, Shah A, Pietrobon R. Willingness to participate in clinical trials among patients of Chinese heritage: a meta-synthesis. Plos One. 2013;8(1):e51328-null. PubMed PMID: 23349672. Full Text Open Access Copy Link to Item
  - Anderson KL, Limkakeng A, Damuth E, Chandra A. Cardiac evaluation for structural abnormalities may not be required in patients presenting with syncope and a normal ECG result in an observation unit setting. Annals of Emergency Medicine. 2012 Oct;60(4):478-84.e1. PubMed Central PMCID: 22632775. Full Text
  - Hocker MB, Villani JJ, Borawski JB, Evans CS, Nelson SM, Gerardo CJ, Limkakeng AT. Dental visits to a North Carolina emergency department: a painful problem. N C Med J. 2012 Sep;73(5):346-351. PubMed PMID: 23189415. Link to Item
  - Limkakeng AT, Glickman SW, Shofer F, Mani G, Drake W, Freeman D, Ascher S, Pietrobon R, Cairns CB. Are patients with longer emergency department wait times less likely to consent to research?. Acad Emerg Med. 2012 Apr;19(4):396-401. PubMed PMID: 22506943. Full Text Open Access Copy Link to Item
  - Limkakeng AT, Drake W, Mani G, Freeman D, Best R, Newby LK, Chandra A. Left ventricular dysfunction screening in hypertensive patients with N-terminal pro-B-type natriuretic peptide and electrocardiogram. Am J Emerg Med. 2012 Jan;30(1):214-217. PubMed PMID: 21185671. Full Text Open Access Copy Link to Item
  - Chandra A, Sieck S, Hocker M, Gerardo CJ, Villani J, Harrison D, Boardwine A, Limkakeng A. An observation unit may help improve an institution's Press Ganey satisfaction score. Crit Pathw Cardiol. 2011 Jun;10(2):104-106. PubMed PMID: 21988951. Full Text Link to Item
  - Chandra A, Nicks B, Maniago E, Nouh A, Limkakeng A. A multicenter analysis of the ED diagnosis of pneumonia. Am J Emerg Med. 2010 Oct;28(8):862-865. PubMed PMID: 20887906. Full Text Link to Item
  - Limkakeng AT, Chandra A. Impact of renal dysfunction on acute coronary syndrome evaluation in observation unit patients. Am J Emerg Med. 2010 Jul;28(6):658-662. PubMed PMID: 20637379. Full Text Open Access Copy Link to Item
  - Chandra A, Lindsell CJ, Limkakeng A, Diercks DB, Hoekstra JW, Hollander JE, Kirk JD, Peacock WF, Gibler WB, Pollack CV, EMCREG i*trACS Investigators . Emergency physician high pretest probability for acute coronary syndrome correlates with adverse cardiovascular outcomes. Acad Emerg Med. 2009 Aug;16(8):740-748. PubMed PMID: 19673712. Full Text Link to Item
  - Limkakeng AT, Glickman SW, Cairns CB, Chandra A. Unsuspected pulmonary embolism in observation unit patients. West J Emerg Med. 2009 Aug;10(3):130-134. PubMed PMID: 19718369. Link to Item
  - Takakuwa KM, Shofer FS, Limkakeng AT, Hollander JE. Preferences for cardiac tests and procedures may partially explain sex but not race disparities. Am J Emerg Med. 2008 Jun;26(5):545-550. PubMed PMID: 18534282. Full Text Link to Item
  - Limkakeng AT, Halpern E, Takakuwa KM. Sixty-four-slice multidetector computed tomography: the future of ED cardiac care. Am J Emerg Med. 2007 May;25(4):450-458. PubMed PMID: 17499666. (Review) Full Text Link to Item
  - Sherman SC, Limkakeng A. Xanthogranulomatous pyelonephritis with a nephrocutaneous fistula. J Emerg Med. 2005 Oct;29(3):337-338. PubMed PMID: 16183456. Full Text Link to Item
  - Limkakeng A, Gibler WB, Pollack C, Hoekstra JW, Sites F, Shofer FS, Tiffany B, Wilke E, Hollander JE. Combination of Goldman risk and initial cardiac troponin I for emergency department chest pain patient risk stratification. Acad Emerg Med. 2001 Jul;8(7):696-702. PubMed PMID: 11435183. Link to Item
- Other Articles
  - A Randomized Trial of Protocol-Based Care for Early Septic Shock. New England Journal of Medicine. 2014 May;370(18):1683-1693. Full Text Open Access Copy
  - Limkakeng A, Broder JS, Theiling BJ. Chicken or egg? Risks of misattribution of cause-effect relationships in studies of association. Acad Emerg Med. 2013 Sep;20(9):965-. PubMed PMID: 23981076. (Letter) Full Text Link to Item
  - Limkakeng AT. Emergency Medicine national conventions: a medical student's perspective. J Emerg Med. 2002 Aug;23(2):211-212. PubMed PMID: 12359299. Link to Item
Scholarly, Clinical, & Service Activities
Presentations & Appearances
Outreach & Engaged Scholarship
- Bass Connections Faculty Team Member . Stemming the Opiate Epidemic through Education and Outreach. August 2017 - May 2018 2017 - 2018
Service to the Profession
- Co-Director. American College of Emergency Physicians Scientific Assembly Research Forum. American College of Emergency Physicians. 2015 - 2017 2015 - 2017

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Education, Training, & Certifications

Duke Appointment History

Leadership & Clinical Positions at Duke

Academic Positions Outside Duke

In the News

Awards & Honors

Subject Headings

Selected Grants

Selected Publications

Book Sections

Conference Papers

Journal Articles

Other Articles

Presentations & Appearances

Outreach & Engaged Scholarship

Service to the Profession