Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Ph.D., University of Virginia
  • M.D., Virginia Commonwealth University 1986
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  Previous Appointments & Affiliations

  • Consulting Associate in the Department of Medicine, Medicine, Cardiology, Medicine 1994 - 2013
• Publications & Artistic Works
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  Selected Publications

  • Academic Articles

    • Paraschos, Alexander, Dwayne Callwood, Marilyn B. Wightman, James E. Tcheng, Harry R. Phillips, Gary L. Stiles, John M. Daniel, and Michael H. Sketch. “Outcomes following elective percutaneous coronary intervention without on-site surgical backup in a community hospital.” Am J Cardiol 95, no. 9 (May 1, 2005): 1091–93. https://doi.org/10.1016/j.amjcard.2004.12.066.
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    • Glotzer, T. V., R. Yee, A. S. Hellkamp, R. Marinchak, J. Cook, A. Paraschos, G. Radoslovich, et al. “Arrhythmia monitoring through pacemakers - Response.” Circulation 108, no. 15 (October 14, 2003): E109–E109.
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    • Glotzer, Taya V., Anne S. Hellkamp, John Zimmerman, Michael O. Sweeney, Raymond Yee, Roger Marinchak, James Cook, et al. “Atrial high rate episodes detected by pacemaker diagnostics predict death and stroke: report of the Atrial Diagnostics Ancillary Study of the MOde Selection Trial (MOST).” Circulation 107, no. 12 (April 1, 2003): 1614–19. https://doi.org/10.1161/01.CIR.0000057981.70380.45.
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    • Paraschos, A., and J. S. Karliner. “Receptor crosstalk: effects of prolonged carbachol exposure on beta 1-adrenoceptors and adenylyl cyclase activity in neonatal rat ventricular myocytes.” Naunyn Schmiedebergs Arch Pharmacol 350, no. 3 (September 1994): 267–76. https://doi.org/10.1007/BF00175032.
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    • Reupcke, C., A. Paraschos, N. Honbo, and J. S. Karliner. “A phorbol ester augments cAMP content and adenylyl cyclase activity in neonatal rat cardiac myocytes despite reduced beta adrenoceptor density.” Cardiovasc Res 27, no. 12 (December 1993): 2179–85. https://doi.org/10.1093/cvr/27.12.2179.
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    • Eisenberg, M. J., S. A. Rice, A. Paraschos, G. R. Caputo, and N. B. Schiller. “The clinical spectrum of patients with aneurysms of the ascending aorta.” Am Heart J 125, no. 5 Pt 1 (May 1993): 1380–85. https://doi.org/10.1016/0002-8703(93)91011-3.
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    • Paraschos, A., J. M. Gonzalez-Ros, and M. Martinez-Carrion. “Absorption filtration. A tool for the measurement of ion tracer flux in native membranes and reconstituted lipid vesicles.” Biochim Biophys Acta 733, no. 2 (September 7, 1983): 223–33. https://doi.org/10.1016/0005-2736(83)90526-6.
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    • Paraschos, A., J. M. Gonzalez-Ros, and M. Martinez-Carrion. “Acetylcholine receptor from Torpedo. Preferential solubilization and efficient reintegration into lipid vesicles.” Biochim Biophys Acta 691, no. 2 (October 7, 1982): 249–60. https://doi.org/10.1016/0005-2736(82)90414-x.
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    • Gonzalez-Ros, J. M., M. Llanillo, A. Paraschos, and M. Martinez-Carrion. “Lipid environment of acetylcholine receptor from Torpedo californica.” Biochemistry 21, no. 14 (July 6, 1982): 3467–74. https://doi.org/10.1021/bi00257a033.
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    • Farach, M. C., M. Mihovilovic, A. Paraschos, and M. Martinez-Carrion. “Effect of anti-acetylcholine receptor Fab fragments from goats on functional membrane-bound receptor.” Arch Biochem Biophys 214, no. 1 (March 1982): 140–54. https://doi.org/10.1016/0003-9861(82)90016-9.
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    • Martinez-Carrion, M., J. M. Gonzalez-Ros, M. Llanillo, and A. Paraschos. “Acetylcholine receptors from electroplax membranes: in vitro and in situ properties.” Adv Exp Med Biol 148 (1982): 209–22. https://doi.org/10.1007/978-1-4615-9281-5_17.
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    • Gonzalez-Ros, J. M., A. Paraschos, M. C. Farach, and M. Martinez-Carrion. “Characterization of acetylcholine receptor isolated from Torpedo californica electroplax through the use of an easily removable detergent, beta-D-octylglucopyranoside.” Biochim Biophys Acta 643, no. 2 (May 6, 1981): 407–20. https://doi.org/10.1016/0005-2736(81)90085-7.
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    • Gonzalez-Ros, J. M., A. Paraschos, and M. Martinez-Carrion. “Reconstitution of functional membrane-bound acetylcholine receptor from isolated Torpedo californica receptor protein and electroplax lipids.” Proc Natl Acad Sci U S A 77, no. 4 (April 1980): 1796–1800. https://doi.org/10.1073/pnas.77.4.1796.
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  • Conference Papers

    • Glotzer, T. V., A. S. Hellkamp, J. Zimmerman, M. Sweeney, R. Yee, R. Marinchak, J. Cook, et al. “Symptoms are an unreliable predictor of the presence of clinically important supraventricular tachycardias: Report of the atrial diagnostics ancillary study of MOST.” In Circulation, 106:603–603. LIPPINCOTT WILLIAMS & WILKINS, 2002.
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    • Moliterno, D. J., R. A. Harrington, M. W. Krucoff, P. W. Armstrong, F. VandeWerf, A. Kristinsson, W. Hui, et al. “More complete and stable reperfusion with platelet IIb/IIIa antagonism plus thrombolysis for AMI: The PARADIGM trial.” In Circulation, 94:3232–3232. AMER HEART ASSOC, 1996.
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    • PARASCHOS, A., D. K. HINES, R. MATSUO, and J. S. KARLINER. “A PHORBOL ESTER ENHANCES BOTH BETA-1-ADRENOCEPTOR DOWN-REGULATION AND ADENYLYL CYCLASE ACTIVITY.” In Circulation, 82:176–176. AMER HEART ASSOC, 1990.
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    • PARASCHOS, A., G. A. HASTINGS, and J. S. KARLINER. “RECEPTOR CROSSTALK - EFFECTS OF CARBACHOL ON BETA-1-RECEPTORS AND ADENYLYL CYCLASE ACTIVITY.” In Circulation, 82:176–176. AMER HEART ASSOC, 1990.
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    • GONZALEZROS, J. M., M. LLANILLO, A. PARASCHOS, J. A. FERRAGUT, and M. MARTINEZCARRION. “DETERGENT SOLUBILIZATION IN THE STUDY OF ACETYLCHOLINE-RECEPTOR LIPID ASSOCIATIONS.” In Biochemistry, 23:3362–3362. AMER CHEMICAL SOC, 1984.
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    • GONZALEZROS, J. M., M. LLANILLO, A. PARASCHOS, J. A. FERRAGUT, and M. MARTINEZCARRION. “DETERGENT SOLUBILIZATION IN THE STUDY OF ACETYLCHOLINE-RECEPTOR LIPID ASSOCIATIONS.” In Abstracts of Papers of the American Chemical Society, 188:88-BIOL. AMER CHEMICAL SOC, 1984.
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    • LLANILLO, M., J. M. GONZALEZROS, A. PARASCHOS, and M. MARTINEZCARRION. “FEATURES OF THE LIPID MATRIX VS ACETYLCHOLINE-RECEPTOR FUNCTIONALITY.” In Federation Proceedings, 41:1396–1396. FEDERATION AMER SOC EXP BIOL, 1982.
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    • PARASCHOS, A., J. M. GONZALEZROS, and M. MARTINEZCARRION. “REINTEGRATION OF FUNCTIONAL ACETYLCHOLINE-RECEPTOR INTO LIPID VESICLES.” In Federation Proceedings, 41:1396–1396. FEDERATION AMER SOC EXP BIOL, 1982.
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    • PARASCHOS, A., J. M. GONZALEZROS, and M. MARTINEZCARRION. “RECONSTITUTION OF BIOLOGICALLY-ACTIVE MEMBRANE-VESICLES CONTAINING PURIFIED ACETYLCHOLINE-RECEPTOR.” In Federation Proceedings, 39:1813–1813. FEDERATION AMER SOC EXP BIOL, 1980.
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