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Amareswararao Kavuri

Postdoctoral Associate

Selected Publications

Examining the Influence of Digital Phantom Models in Virtual Imaging Trials for Tomographic Breast Imaging.

Journal Article ArXiv · February 1, 2024 PURPOSE: Digital phantoms are one of the key components of virtual imaging trials (VITs) that aims to assess and optimize new medical imaging systems and algorithms. However, these phantoms vary in their voxel resolution, appearance and structural details. ... Link to item Cite

Quantitative accuracy of lung function measurement using parametric response mapping: A virtual imaging study.

Conference Proc SPIE Int Soc Opt Eng · February 2024 Parametric response mapping (PRM) is a voxel-based quantitative CT imaging biomarker that measures the severity of chronic obstructive pulmonary disease (COPD) by analyzing both inspiratory and expiratory CT scans. Although PRM-derived measurements have be ... Full text Link to item Cite

Development and Application of a Virtual Imaging Trial Framework for Longitudinal Quantification of Emphysema in CT.

Journal Article Proc SPIE Int Soc Opt Eng · February 2024 Pulmonary emphysema is a progressive lung disease that requires accurate evaluation for optimal management. This task, possible using quantitative CT, is particularly challenging as scanner and patient attributes change over time, negatively impacting the ... Full text Link to item Cite

Virtual NLST: Towards Replicating National Lung Screening Trial

Conference Progress in Biomedical Optics and Imaging - Proceedings of SPIE · January 1, 2024 Virtual Imaging Trials, known as VITs, provide a computational substitute for clinical trials. These traditional trials tend to be sluggish, costly, and frequently deficient in definitive evidence, all the while subjecting participants to ionizing radiatio ... Full text Cite

Sources of image texture variation in tomographic breast imaging

Conference Medical Imaging 2022: Image Perception, Observer Performance, and Technology Assessment · April 5, 2022 Full text Cite

Relative Contributions of Anatomical and Quantum Noise in Signal Detection and Perception of Tomographic Digital Breast Images.

Journal Article IEEE transactions on medical imaging · November 2020 Anatomical and quantum noise inhibits detection of malignancies in clinical images such as in digital mammography (DM), digital breast tomosynthesis (DBT) and breast CT (bCT). In this work, we examine the relative influence and interactions of these two ty ... Full text Cite

On the correlation between second order texture features and human observer detection performance in digital images.

Journal Article Scientific reports · August 2020 Image texture, the relative spatial arrangement of intensity values in an image, encodes valuable information about the scene. As it stands, much of this potential information remains untapped. Understanding how to decipher textural details would afford an ... Full text Open Access Cite

Multi-step material decomposition for spectral computed tomography.

Journal Article Physics in medicine and biology · July 2019 Spectral images from photon counting detectors are being explored for material decomposition applications such as for obtaining quantitative maps of tissue types and contrast agents. While these detectors allow acquisition of multi-energy data in a single ... Full text Cite

Single-exposure contrast enhanced spectral mammography

Conference Progress in Biomedical Optics and Imaging - Proceedings of SPIE · January 1, 2019 Contrast-enhanced spectral mammography (CESM) is being implemented to overcome the limitations of conventional mammography where tumor visualization is obstructed by overlapping glandular tissue. CESM exploits the spectral properties of a contrast agent by ... Full text Cite

A sensitivity analysis on parameters that affect a multi-step material decomposition for spectral CT

Conference Progress in Biomedical Optics and Imaging - Proceedings of SPIE · January 1, 2018 When using a photon counting detector (PCD) for material decomposition problems, a major issue is the low-count rate per energy bin which may lead to high image-noise with compromised contrast and accuracy. We recently proposed a multi-step algorithmic met ... Full text Cite

Investigating the contributions of anatomical variations and quantum noise to image texture in digital breast tomosynthesis

Conference Progress in Biomedical Optics and Imaging - Proceedings of SPIE · January 1, 2018 Our previous work on DBT image texture indicates that certain texture features may impact human observer performance for the task of low-contrast mass detection. Despite this, little is yet known about these texture statistics in the context of medical ima ... Full text Cite

Interaction of anatomic and quantum noise in DBT power spectrum

Conference Progress in Biomedical Optics and Imaging - Proceedings of SPIE · January 1, 2018 In x-ray breast images, anatomical variations have been characterized by slope of the noise power spectrum (NPS) that follows an inverse power-law relationship. Prior literature has reported that this slope (β) changes with imaging modality (DBT vs. mammog ... Full text Cite

On the impact of local image texture parameters on search and localization in digital breast imaging

Conference Progress in Biomedical Optics and Imaging - Proceedings of SPIE · January 1, 2017 Understanding factors that influence search and localization of signals in tomographic breast imaging can allow for the development of efficient system design and image displays. Several acquisition, reconstruction and display parameters are known to influ ... Full text Cite