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Alexander J. Hartemink

Professor of Computer Science
Computer Science
Box 90129, Durham, NC 27708-0129
308 Research Drive, LSRC D239, Durham, NC 27708-0129

Overview


Computational biology, machine learning, Bayesian statistics, transcriptional regulation, genomics and epigenomics, graphical models, Bayesian networks, hidden Markov models, systems biology, computational neurobiology, classification, feature selection

Current Appointments & Affiliations


Professor of Computer Science · 2013 - Present Computer Science, Trinity College of Arts & Sciences
Professor of Biology · 2013 - Present Biology, Trinity College of Arts & Sciences
Bass Fellow · 2014 - Present Computer Science, Trinity College of Arts & Sciences

In the News


Published January 10, 2022
Babs Wise: Paving the Road to a Rhodes
Published February 22, 2016
12 Duke Graduates Named Fulbright Scholars
Published January 6, 2015
Genomics Team Wins $5.9 Million Grant

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Recent Publications


Inferring differential protein binding from time-series chromatin accessibility data.

Journal Article Bioinformatics advances · January 2025 MotivationDue to internal and external factors, the epigenomic landscape is constantly changing in ways that are linked to changes in gene expression. Chromatin accessibility data, such as MNase-seq, provide valuable insights into this landscape a ... Full text Cite
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Recent Grants


Methods to Elucidate the Dynamic Interplay of Transcriptional Regulation and Chromatin Occupancy

ResearchPrincipal Investigator · Awarded by National Institute of General Medical Sciences · 2021 - 2026

Elucidating the Molecular Basis of Cellular Metal Stress by using Mass Spectrometry-Based Proteomic Methods

ResearchCollaborator · Awarded by National Institute of General Medical Sciences · 2022 - 2026

IRES Track 1 IRTG Engaged in Dissecting and Reengineering the Regulatory Genome

ResearchMentor · Awarded by National Science Foundation · 2019 - 2023

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Education, Training & Certifications


Massachusetts Institute of Technology · 2001 Ph.D.
University of Oxford (United Kingdom) · 1996 M.Phil.
Duke University · 1994 B.S.