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Amy Martha Pastva

Professor in Orthopaedic Surgery
Orthopaedic Surgery, Physical Therapy
DUMC 104002, Durham, NC 27710
311 Trent Drive, Durham, NC 27710

Overview


The major themes that embody Dr. Pastva's scholarly pursuits include:  a) mechanisms of physical reserve and resilience; b) rehabilitation strategies for improving the health and function of individuals living with chronic cardiovascular and pulmonary diseases and/or surviving critical illness; and c) pedagogical strategies that will optimize health professions curricula to address clinical practice expectations in aging and acute or critical illness. In addition to her faculty appointments, she is Director of Research in the Physical Therapy Division, a Senior Fellow in the Duke Center for the Study of Aging and Human Development, a Duke Pepper Older American Independence Center (OAIC) Scholar, and co-lead of the Center’s Health and Mobility Measures Core. She serves as an advisor in Duke Health's Cardiovascular and Pulmonary Physical Therapy Residency Program. She also serves on the American Physical Therapy Association’s ICU Rehabilitation Clinical Guideline Development Group, on the Research Committee of its Cardiovascular and Pulmonary Academy, and on the Editorial Board of the Physical Therapy & Rehabilitation Journal.

Current Appointments & Affiliations


Professor in Orthopaedic Surgery · 2022 - Present Orthopaedic Surgery, Physical Therapy, Orthopaedic Surgery
Professor in Medicine · 2022 - Present Medicine, Pulmonary, Allergy, and Critical Care Medicine, Medicine
Professor in Population Health Sciences · 2022 - Present Population Health Sciences, Basic Science Departments
Professor in Cell Biology · 2022 - Present Cell Biology, Basic Science Departments
Member of the Duke Cancer Institute · 2023 - Present Duke Cancer Institute, Institutes and Centers
Member in the Duke Clinical Research Institute · 2023 - Present Duke Clinical Research Institute, Institutes and Centers

Recent Publications


Circulating Biomarkers as Predictors of Improvement in Physical Function in Hospitalized Older Adults With Geriatric Syndromes: Findings From the REHAB-HF Trial.

Journal Article Circ Heart Fail · January 7, 2026 BACKGROUND: Biomarkers in heart failure (HF) provide mechanistic and prognostic insights, but their role in predicting treatment response is less understood. We evaluated whether multiple baseline biomarker profiles from the REHAB-HF trial (Rehabilitation ... Full text Link to item Cite

Understanding Patient and Care Partner Experiences With Rehabilitation After Hospitalization for Advanced Heart Failure: "I Was Thinking I'd Just Be Like I Was Before I Got This".

Journal Article Phys Ther · December 6, 2025 IMPORTANCE: Advanced Heart failure (HF) is a life-limiting condition that frequently necessitates hospitalization and subsequent post-acute rehabilitation for older adults. Despite high rates of post-acute care utilization, a notable gap exists in understa ... Full text Link to item Cite

Sex Differences in Efficacy of Multidomain Rehabilitation Among Older Adults With Acute HF: The REHAB-HF Trial.

Journal Article JACC Heart Fail · November 2025 BACKGROUND: A multidomain physical rehabilitation intervention (REHAB-HF [Rehabilitation Therapy in Older Acute Heart Failure Patients] intervention) has been associated with significant improvements in physical function and quality of life (QOL) among old ... Full text Link to item Cite
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Recent Grants


Remotely Monitored, Mobile health-supported High Intensity Interval Training after COVID-19 Critical Illness (REMM HIIT-Covid19)

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2021 - 2027

Physical Rehabilitation for Older Patients with Acute HFpEF-The REHAB-HFpEF Trial - Site Administration

Clinical TrialIntervention Coordinator · Awarded by Wake Forest University Health Sciences · 2023 - 2027

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Education, Training & Certifications


University of Alabama, Birmingham · 2004 Ph.D.