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Ana Maria Gaca

Consulting Associate in the Department of Radiology
Radiology, Pediatric Radiology
Box 3808 Med Ctr, Durham, NC 27710
Dept of Radiology, Durham, NC 27710

Selected Publications


Successful treatment of pediatric histiocytic sarcoma using abbreviated high-risk leukemia chemotherapy.

Journal Article Pediatr Blood Cancer · October 2014 Histiocytic sarcoma (HS) is a malignant tumor composed of proliferating cells of histiocytic origin. True HS is exceedingly rare, particularly in pediatric patients. These tumors are frequently aggressive, and outcome for patients with HS has traditionally ... Full text Link to item Cite

Comparison of conventional and simulated reduced-tube current MDCT for evaluation of suspected appendicitis in the pediatric population.

Journal Article AJR Am J Roentgenol · September 2013 OBJECTIVE: The purpose of this study was to compare CT with conventional and simulated reduced-tube current in the evaluation for acute appendicitis in children. MATERIALS AND METHODS: Validated noise-addition (tube current-reduction) software was used to ... Full text Link to item Cite

MLL duplication in a pediatric patient with B-cell lymphoblastic lymphoma.

Journal Article J Pediatr Hematol Oncol · April 2012 Lymphoblastic lymphoma is the second most common type of non-Hodgkin lymphoma seen in children. Approximately, 90% of lymphoblastic lymphomas arise from T cells, with the remaining 10% being B-cell-lineage derived. Although T-cell lymphoblastic lymphoma mo ... Full text Link to item Cite

Lung nodule detection in pediatric chest CT: quantitative relationship between image quality and radiologist performance.

Journal Article Med Phys · May 2011 PURPOSE: To determine the quantitative relationship between image quality and radiologist performance in detecting small lung nodules in pediatric CT. METHODS: The study included clinical chest CT images of 30 pediatric patients (0-16 years) scanned at tub ... Full text Link to item Cite

Evaluation of wedging of lower thoracic and upper lumbar vertebral bodies in the pediatric population.

Journal Article AJR Am J Roentgenol · February 2010 OBJECTIVE: Anterior wedging of thoracolumbar vertebral bodies is often seen in children. The purpose of our study was to show whether mild anterior wedging of pediatric thoracolumbar junction vertebral bodies can be seen as a normal variant, rather than as ... Full text Link to item Cite

Basketball injuries in children.

Journal Article Pediatr Radiol · December 2009 Basketball is a popular, worldwide sport played outdoors and indoors year-round. Patterns of injury are related to abrupt changes in the athlete's direction, jumping, contact between athletes, the hard playing surface and paucity of protective equipment. I ... Full text Link to item Cite

A young patient with polyarthralgia and hearing loss: a case report of Muenke syndrome.

Journal Article Skeletal Radiol · October 2009 There are few reports of the typical radiographic findings in the hands and feet of patients with Muenke syndrome. We present a case report of a young girl with Muenke syndrome, whose diagnosis was made following the observation of coalitions and coned epi ... Full text Link to item Cite

Enhancing pediatric safety: assessing and improving resident competency in life-threatening events with a computer-based interactive resuscitation tool.

Journal Article Pediatr Radiol · July 2009 BACKGROUND: Though rare, allergic reactions occur as a result of administration of low osmolality nonionic iodinated contrast material to pediatric patients. Currently available resuscitation aids are inadequate in guiding radiologists' initial management ... Full text Link to item Cite

Pediatric MDCT: towards assessing the diagnostic influence of dose reduction on the detection of small lung nodules.

Journal Article Acad Radiol · July 2009 RATIONALE AND OBJECTIVES: The purpose of this study was to evaluate the effect of reduced tube current (dose) on lung nodule detection in pediatric multidetector array computed tomography (MDCT). MATERIALS AND METHODS: The study included normal clinical ch ... Full text Link to item Cite

Three-dimensional simulation of lung nodules for paediatric multidetector array CT.

Journal Article Br J Radiol · May 2009 The purpose of this study was to develop and validate a technique for three-dimensional (3D) modelling of small lung nodules on paediatric multidetector array computed tomography (MDCT) images. Clinical images were selected from 21 patients (<18 years old) ... Full text Link to item Cite

Aberrant course of the umbilical vein in a newborn with Cornelia de Lange syndrome.

Journal Article Pediatr Radiol · April 2009 Congenital anomalies of the umbilical vein are rare. We describe an aberrant course of the umbilical vein discovered by identifying an unusual umbilical venous catheter course on abdominal radiography in a patient with Cornelia de Lange syndrome. The umbil ... Full text Link to item Cite

The radiology perspective: needs and tools for management of life-threatening events.

Journal Article Pediatr Radiol · November 2008 Studies have shown that life-threatening contrast agent reactions in adults are very rare, and even less common in children. The rarity of severe allergic reactions to contrast material challenges educators to achieve radiology resident competency in this ... Full text Link to item Cite

Repair of congenital heart disease: a primer--Part 2.

Journal Article Radiology · July 2008 This review, the second of two parts, describes the repair of aortic arch anomalies, left-to-right shunts, valvular disease, tetralogy of Fallot, and truncus arteriosus. Cardiac transplantation is also discussed. Advances in the surgical management of cong ... Full text Link to item Cite

Radiologists' agreement when using a 10-point scale to report abdominal radiographic findings of necrotizing enterocolitis in neonates and infants.

Journal Article AJR Am J Roentgenol · July 2008 OBJECTIVE: The purpose of this study was to evaluate radiologists' agreement when using a 10-point scale of abnormal findings designed to standardize reporting of abdominal radiographs in neonates or infants with suspected necrotizing enterocolitis. MATERI ... Full text Link to item Cite

Repair of congenital heart disease: a primer-part 1.

Journal Article Radiology · June 2008 Advances in the surgical management of congenital heart disease have led to enhanced patient survival and quality of life. Improvements in technology in computed tomography and magnetic resonance imaging have resulted in increasing use of cross-sectional i ... Full text Link to item Cite

Radiation doses from small-bowel follow-through and abdomen/pelvis MDCT in pediatric Crohn disease.

Journal Article Pediatr Radiol · March 2008 BACKGROUND: The onset of Crohn disease (CD) can occur in childhood. Imaging, which often involves radiation, is frequent in CD both for disease diagnosis and follow-up. However, information regarding radiation dose for contemporary CT and fluoroscopy is no ... Full text Link to item Cite

Radiation doses from small-bowel follow-through and abdominopelvic MDCT in Crohn's disease.

Journal Article AJR Am J Roentgenol · November 2007 OBJECTIVE: The purpose of our study was to compare organ and effective doses for small-bowel follow-through (SBFT) and abdominopelvic MDCT in adults with Crohn's disease, to retrospectively evaluate the number of radiographic examinations performed for Cro ... Full text Link to item Cite

Enhancing pediatric safety: using simulation to assess radiology resident preparedness for anaphylaxis from intravenous contrast media.

Journal Article Radiology · October 2007 PURPOSE: To prospectively develop and test a simulation model for assessing radiology resident preparedness for pediatric life-threatening events in the radiology environment. MATERIALS AND METHODS: This study was institutional review board approved. Ninet ... Full text Link to item Cite

Osteosarcomatosis.

Journal Article Pediatr Radiol · July 2007 Full text Link to item Cite

Successful treatment of pediatric histiocytic sarcoma using abbreviated high-risk leukemia chemotherapy.

Journal Article Pediatr Blood Cancer · October 2014 Histiocytic sarcoma (HS) is a malignant tumor composed of proliferating cells of histiocytic origin. True HS is exceedingly rare, particularly in pediatric patients. These tumors are frequently aggressive, and outcome for patients with HS has traditionally ... Full text Link to item Cite

Comparison of conventional and simulated reduced-tube current MDCT for evaluation of suspected appendicitis in the pediatric population.

Journal Article AJR Am J Roentgenol · September 2013 OBJECTIVE: The purpose of this study was to compare CT with conventional and simulated reduced-tube current in the evaluation for acute appendicitis in children. MATERIALS AND METHODS: Validated noise-addition (tube current-reduction) software was used to ... Full text Link to item Cite

MLL duplication in a pediatric patient with B-cell lymphoblastic lymphoma.

Journal Article J Pediatr Hematol Oncol · April 2012 Lymphoblastic lymphoma is the second most common type of non-Hodgkin lymphoma seen in children. Approximately, 90% of lymphoblastic lymphomas arise from T cells, with the remaining 10% being B-cell-lineage derived. Although T-cell lymphoblastic lymphoma mo ... Full text Link to item Cite

Lung nodule detection in pediatric chest CT: quantitative relationship between image quality and radiologist performance.

Journal Article Med Phys · May 2011 PURPOSE: To determine the quantitative relationship between image quality and radiologist performance in detecting small lung nodules in pediatric CT. METHODS: The study included clinical chest CT images of 30 pediatric patients (0-16 years) scanned at tub ... Full text Link to item Cite

Evaluation of wedging of lower thoracic and upper lumbar vertebral bodies in the pediatric population.

Journal Article AJR Am J Roentgenol · February 2010 OBJECTIVE: Anterior wedging of thoracolumbar vertebral bodies is often seen in children. The purpose of our study was to show whether mild anterior wedging of pediatric thoracolumbar junction vertebral bodies can be seen as a normal variant, rather than as ... Full text Link to item Cite

Basketball injuries in children.

Journal Article Pediatr Radiol · December 2009 Basketball is a popular, worldwide sport played outdoors and indoors year-round. Patterns of injury are related to abrupt changes in the athlete's direction, jumping, contact between athletes, the hard playing surface and paucity of protective equipment. I ... Full text Link to item Cite

A young patient with polyarthralgia and hearing loss: a case report of Muenke syndrome.

Journal Article Skeletal Radiol · October 2009 There are few reports of the typical radiographic findings in the hands and feet of patients with Muenke syndrome. We present a case report of a young girl with Muenke syndrome, whose diagnosis was made following the observation of coalitions and coned epi ... Full text Link to item Cite

Enhancing pediatric safety: assessing and improving resident competency in life-threatening events with a computer-based interactive resuscitation tool.

Journal Article Pediatr Radiol · July 2009 BACKGROUND: Though rare, allergic reactions occur as a result of administration of low osmolality nonionic iodinated contrast material to pediatric patients. Currently available resuscitation aids are inadequate in guiding radiologists' initial management ... Full text Link to item Cite

Pediatric MDCT: towards assessing the diagnostic influence of dose reduction on the detection of small lung nodules.

Journal Article Acad Radiol · July 2009 RATIONALE AND OBJECTIVES: The purpose of this study was to evaluate the effect of reduced tube current (dose) on lung nodule detection in pediatric multidetector array computed tomography (MDCT). MATERIALS AND METHODS: The study included normal clinical ch ... Full text Link to item Cite

Three-dimensional simulation of lung nodules for paediatric multidetector array CT.

Journal Article Br J Radiol · May 2009 The purpose of this study was to develop and validate a technique for three-dimensional (3D) modelling of small lung nodules on paediatric multidetector array computed tomography (MDCT) images. Clinical images were selected from 21 patients (<18 years old) ... Full text Link to item Cite

Aberrant course of the umbilical vein in a newborn with Cornelia de Lange syndrome.

Journal Article Pediatr Radiol · April 2009 Congenital anomalies of the umbilical vein are rare. We describe an aberrant course of the umbilical vein discovered by identifying an unusual umbilical venous catheter course on abdominal radiography in a patient with Cornelia de Lange syndrome. The umbil ... Full text Link to item Cite

The radiology perspective: needs and tools for management of life-threatening events.

Journal Article Pediatr Radiol · November 2008 Studies have shown that life-threatening contrast agent reactions in adults are very rare, and even less common in children. The rarity of severe allergic reactions to contrast material challenges educators to achieve radiology resident competency in this ... Full text Link to item Cite

Repair of congenital heart disease: a primer--Part 2.

Journal Article Radiology · July 2008 This review, the second of two parts, describes the repair of aortic arch anomalies, left-to-right shunts, valvular disease, tetralogy of Fallot, and truncus arteriosus. Cardiac transplantation is also discussed. Advances in the surgical management of cong ... Full text Link to item Cite

Radiologists' agreement when using a 10-point scale to report abdominal radiographic findings of necrotizing enterocolitis in neonates and infants.

Journal Article AJR Am J Roentgenol · July 2008 OBJECTIVE: The purpose of this study was to evaluate radiologists' agreement when using a 10-point scale of abnormal findings designed to standardize reporting of abdominal radiographs in neonates or infants with suspected necrotizing enterocolitis. MATERI ... Full text Link to item Cite

Repair of congenital heart disease: a primer-part 1.

Journal Article Radiology · June 2008 Advances in the surgical management of congenital heart disease have led to enhanced patient survival and quality of life. Improvements in technology in computed tomography and magnetic resonance imaging have resulted in increasing use of cross-sectional i ... Full text Link to item Cite

Radiation doses from small-bowel follow-through and abdomen/pelvis MDCT in pediatric Crohn disease.

Journal Article Pediatr Radiol · March 2008 BACKGROUND: The onset of Crohn disease (CD) can occur in childhood. Imaging, which often involves radiation, is frequent in CD both for disease diagnosis and follow-up. However, information regarding radiation dose for contemporary CT and fluoroscopy is no ... Full text Link to item Cite

Radiation doses from small-bowel follow-through and abdominopelvic MDCT in Crohn's disease.

Journal Article AJR Am J Roentgenol · November 2007 OBJECTIVE: The purpose of our study was to compare organ and effective doses for small-bowel follow-through (SBFT) and abdominopelvic MDCT in adults with Crohn's disease, to retrospectively evaluate the number of radiographic examinations performed for Cro ... Full text Link to item Cite

Enhancing pediatric safety: using simulation to assess radiology resident preparedness for anaphylaxis from intravenous contrast media.

Journal Article Radiology · October 2007 PURPOSE: To prospectively develop and test a simulation model for assessing radiology resident preparedness for pediatric life-threatening events in the radiology environment. MATERIALS AND METHODS: This study was institutional review board approved. Ninet ... Full text Link to item Cite

Osteosarcomatosis.

Journal Article Pediatr Radiol · July 2007 Full text Link to item Cite

Intestinal malrotation in neonates with nonbilious emesis.

Journal Article J Perinatol · June 2006 Intestinal malrotation is a relatively uncommon condition with diverse outcomes. Familiarity with variations in the presentation of malrotation is imperative as early diagnosis and prompt subsequent surgical intervention are essential to optimizing outcome ... Full text Link to item Cite