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Andrea Gail Nackley

Associate Professor in Anesthesiology
Anesthesiology
Box 3094, Mail Sort #50, Durham, NC 27710
3 Genome Court, #6120, Durham, NC 27710

Selected Grants


Pharmacological Sciences Training Program

Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2025 - 2030

Neuro-immune modulation of pain in health and disease

ResearchCo Investigator · Awarded by National Institute of Dental and Craniofacial Research · 2022 - 2027

Identification and validation of LPA/LPAR signaling in temporomandibular disorder pain

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2024 - 2027

Development of Adrb3 Antagonists for the Treatment of Pain

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2023 - 2026

Integrated Training in Anesthesiology Research

Inst. Training Prgm or CMEMentor · Awarded by National Institute of General Medical Sciences · 1996 - 2026

A novel clinically- relevant mouse model of chronic overlapping pain conditions for screening analgesics

ResearchPrincipal Investigator · Awarded by National Institute of Neurological Disorders and Stroke · 2022 - 2025

Peripherally-targeted Adrb3 Antagonists for the Treatment of Pain

ResearchPrincipal Investigator · Awarded by University of North Carolina - Chapel Hill · 2023 - 2025

Vestibulodynia: Understanding Pathophysiology and Determining Appropriate Treatments (Vestibulodynia: UPDATe)

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2018 - 2025

MicroRNA 374 as an Epigenetic Regulator of Chronic Pain

FellowshipPrincipal Investigator · Awarded by National Institute of Neurological Disorders and Stroke · 2023 - 2025

ASPET SURF Institutional Award

Inst. Training Prgm or CMEParticipating Faculty Member · Awarded by American Society for Pharmacology and Experimental Therapeutics · 2018 - 2025

Inflammatory Mediators Associated with Resolution of Pain in Distinct Vestibulodynia Subtypes

ResearchPrincipal Investigator · Awarded by National Vulvodynia Association · 2023 - 2024

Defining the role of peripheral Adrb3 in chronic pain and inflammation

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2019 - 2024

Assay Development for characterization of Adrb3 antagonists as pain therapeutics

ResearchPrincipal Investigator · Awarded by Research Triangle Institute International · 2021 - 2023

A novel clinically- relevant mouse model of chronic overlapping pain conditions for screening analgesics

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2022 - 2023

Defining the role of adipocyte-specific Adrb3 in chronic pain

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2018 - 2019

Proteins, MicroRNAs and Genes Associated with TMD and Overlapping Pain Conditions

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2016 - 2018

External Relationships


  • Adaptix LLC
  • NIH Center for Scientific Review
  • US Patent: 9,943,466 B1. ¿Biocompatible Dental Putty Formulations for Controlled Release of Bupivacaine.¿
  • US Provisional Patent: 63/141,794

This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.